scholarly journals Ovarian Fibroma with Serous Cystadenoma—An Unusual Combination: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
P. S. Jayalakshmy ◽  
Usha Poothiode ◽  
G. Krishna ◽  
P. L. Jayalakshmy
Keyword(s):  
English Literature ◽  
Mucinous Cystadenoma ◽  
Ovarian Tumour ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Stromal Tumors ◽  
Extensive Search ◽  
Different Types ◽  
Serous Tumors ◽  
Sex Cord Stromal Tumors

Surface epithelial tumors account for more than 90% of ovarian tumors, of which serous tumors comprise 46%. Sex-cord stromal tumors constitute 8% of ovarian tumors, fibroma being the commonest, comprising 70% in this category. Combination of different types of tumors can occur in ovary with most common being Mucinous cystadenoma and Brenner tumour. We report a case of a very rare combination of ovarian tumour-Fibroma with Serous cystadenoma of the ovary. This combination is not mentioned in any standard textbooks or reference books of gynaecologic pathology. Extensive search of the English Literature showed only one reported case with this combination of ovarian tumors. To the best of our knowledge, this is the second case to be reported in English Literature.

scholarly journals Distribution of various histopathological types of ovarian tumors: A study of 212 cases from a tertiary care center of Eastern Uttar Pradesh

2019 ◽  
Vol 11 (01) ◽  
pp. 075-081 ◽  
Author(s):  
Neha Gupta ◽  
Mahima Yadav ◽  
Vikas Gupta ◽  
Deepshikha Chaudhary ◽  
Shashikant C. U. Patne
Keyword(s):  
Germ Cell ◽  
Who Classification ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Germ Cell Tumors ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Care Hospital ◽  
Stromal Tumors ◽  
Sex Cord Stromal Tumors

Abstract BACKGROUND: Ovarian tumors are one of the leading cancers in females with variable pathological types. This study describes the distribution, clinical and pathological details of various histopathological types of ovarian tumors in a tertiary care hospital in North India. MATERIALS AND METHODS: A retrospective data of 3 years were collected for ovarian tumors submitted to the pathology department of a tertiary care hospital. Data were classified according to the latest World Health Organization (WHO) Classification into epithelial tumors, germ cell tumors, sex cord–stromal tumors, and others. RESULTS: A total of 212 cases of ovarian tumors were studied, 186 were unilateral and 26 were bilateral. Resection specimen, part of specimen, and block review formed 80.2%, 15.1%, 4.7%, respectively. Epithelial tumors formed the majority in 71.7% of cases followed by germ cell tumors (22.2%), sex cord–stromal tumors (3.8%) and others (2.3%). Maximum number of cases in the respective groups occurred in the age groups 31–40, 21–30, 51–60, and 41–50 years, respectively. Overall, benign tumors were 63.7%, malignant tumors were 31.1%, and borderline were 5.2%. The most common histopathological type of benign and malignant tumor was benign serous cystadenoma (18.8%) and serous carcinoma (9.9%), respectively. CONCLUSION: In the present study, ovarian tumors were classified according to the WHO classification, epithelial and germ cell tumors were the major types of ovarian tumors. Benign epithelial tumor formed the majority with 46.2% cases. Serous cystadenoma and mature cystic teratoma were the predominant type of epithelial and germ cell tumors, respectively.

Immunoexpression of Inhibin α Subunit, Inhibin/Activin βA Subunit and CD99 in Ovarian Tumors

2000 ◽  
Vol 124 (4) ◽  
pp. 563-569 ◽  
Author(s):  
Yoon-La Choi ◽  
Hy-Sook Kim ◽  
Geunghwan Ahn
Keyword(s):  
Differential Diagnosis ◽  
Granulosa Cell ◽  
Mucinous Carcinoma ◽  
Ovarian Tumors ◽  
Serous Carcinoma ◽  
Α Subunit ◽  
Stromal Tumors ◽  
Epithelial Tumors ◽  
Krukenberg Tumors ◽  
Sex Cord Stromal Tumors

Abstract Objective.—Anti–inhibin α and inhibin/activin βA subunit and anti-CD99 monoclonal antibodies (mAbs) have recently been demonstrated to be able to label ovarian granulosa cells; thus, they may be of value in the diagnosis of granulosa cell tumors. The present study aimed to determine what combination of these mAbs may be useful for the differential diagnosis of sex cord–stromal tumors of ovary. Design.—Immunohistochemical analyses with anti–inhibin α and inhibin/activin βA subunit antibody and anti-CD99 mAb were performed on 42 ovarian tumors, including sex cord–stromal tumors (29), ovarian epithelial cancers (10), and Krukenberg tumors (3). Results.—All sex cord–stromal tumors were positive for inhibin α subunit, and 17 cases (58.6%) of sex cord–stromal tumors were immunoreactive for inhibin/activin βA subunit. Epithelial tumors and Krukenberg tumors were all negative for inhibin/activin βA subunit except mucinous carcinoma, which showed strong cytoplasmic immunoreactivity. All sex cord–stromal tumors except one granulosa cell tumor showed membranous staining for CD99. A case of serous carcinoma and a case of mucinous carcinoma were positive for CD99, and the remaining epithelial tumors and Krukenberg tumor were all negative for CD99. Conclusions.—The results of immunohistochemical analysis, together with literature review, suggest that inhibin α subunit may be a useful diagnostic marker for sex cord–stromal tumor of the ovary. In addition, anti-CD99 antibody may be useful for the differential diagnosis between ovarian tumors. Inhibin/activin βA subunit has a limited usefulness in the differential diagnosis of ovarian tumor because of its wider immunoreactivity for both sex cord–stromal tumors and mucinous carcinomas. The differential diagnosis of sex cord–stromal tumors of the ovary would be better made with a combined use of both anti–inhibin α subunit and anti-CD99 mAbs.

The Coexistence Of Two Different Epithelial Ovarian Tumors: A Rare Case

2021 ◽  
Vol 17 ◽  
Author(s):  
Ömer Faruk Topaloğlu ◽  
Emine Uysal ◽  
Zeliha Esin Çelik ◽  
Çetin Çelik
Keyword(s):  
Ovarian Tumor ◽  
Cystic Lesion ◽  
Mucinous Cystadenoma ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Lumbar Region ◽  
Fluid Content ◽  
Tumor Subtypes ◽  
Epithelial Tumors ◽  
The Right

Background: Epithelial tumors are the most common subgroup and are seen in 60-70% of all ovarian tumors. Serous cystadenoma and mucinous cystadenoma are the most common benign epithelial tumors. Serous cystadenomas are ovarian tumors with the highest bilateral incidence. The coexistence of tumors with different histopathology in the ovaries is extremely rare and has only been reported in a few cases in the literature. We present a case of bilateral ovarian tumor that was diagnosed as serous and mucinous cystadenoma after laparoscopic surgery. Case report: A 45-year-old female patient was admitted to our center with swelling in the pelvic region and pain in the left lumbar region. US imaging showed a cystic lesion in the right adnexal area, 4x2cm in size, well-circumscribed, containing a few thin septa, and a low echo fluid content. A cystic lesion with 6x4cm sized multilocular, well-circumscribed, slightly high echo fluid content was observed in the left adnexal area. On CT, a complex cystic lesion measuring 6x4cm was observed in the left adnexal area, pushing the left ureter laterally and causing the hydroureter. In addition, a 4x2cm cystic lesion was observed in the right adnexal area and hydroureter was observed on the right side proximal to this lesion. Both lesions were removed by surgery. On histopathologic examination, the left-sided cystic lesion was diagnosed as mucinous cystadenoma, and the right-sided cystic lesion was diagnosed as serous cystadenoma. Conclusion: The coexistence of different ovarian tumor subtypes is rare. In this article, we presented a case in which serous and mucinous cystadenoma lesions were seen together for the fourth time in the literature, according to our knowledge.

scholarly journals Primary Mesenteric Sertoli-Leydig Cell Tumor: A Case Report and Review of the Literature

2008 ◽  
Vol 2008 ◽  
pp. 1-3 ◽  
Author(s):  
Amel Trabelsi ◽  
Soumaya Ben Abdelkarim ◽  
Mohamed Hadfi ◽  
Ridha Fatnaci ◽  
Wided Stita ◽  
...  
Keyword(s):  
Case Report ◽  
Leydig Cell ◽  
English Literature ◽  
Leydig Cell Tumor ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Stromal Tumors ◽  
Sex Cord Stromal Tumors

The occurrence of primary sex cord-stromal tumors at extraovarian sites is exceedingly rare. We report a new case of Sertoli-Leydig cell tumor in the mesentery of a 78-year-old woman who presented with occlusive syndrome and reviewed the previously reported cases of extraovarian sex cord-stromal tumors in the English literature.

scholarly journals CLINICOPATHOLOGICAL STUDY OF OVARIAN NEOPLASMS – AN INSTITUTIONAL PERSPECTIVE

2021 ◽  
pp. 72-76
Author(s):  
VASUNDARA GARDAS ◽  
PRASANTHI CHERUKURI ◽  
SUMERA SALOMI
Keyword(s):  
Ovarian Neoplasms ◽  
Germ Cell Tumors ◽  
Diagnostic Techniques ◽  
Serous Cystadenoma ◽  
Research Data ◽  
Medical Sciences ◽  
Institutional Perspective ◽  
Epithelial Tumor ◽  
Stromal Tumors ◽  
Sex Cord Stromal Tumors

Objective: The objective of the study was to know the frequency and histomorphological patterns of ovarian neoplasms concerning age. Methods: A 2-year retrospective study was done in the pathology department, GITAM Institute of Medical Sciences and Research. Data were retrieved from laboratory records, H & E slides of ovarian biopsies of diagnosed neoplasms were screened. Results: During the study period, 70 ovarian neoplasms were reported. Ovarian tumors were categorized according to the WHO classification. In this study surface, epithelial tumors were most common at 87.14% followed by germ cell tumors at 11.42% and sex cord-stromal tumors at 1.42%. Serous cystadenoma was the most common benign surface epithelial tumor. Conclusion: Histopathology is the gold standard for diagnosing ovarian neoplasms. Newer diagnostic techniques such as immunohistochemistry and morphometric analysis help decide management and prognosis.

Unexpected borderline ovarian tumours (BOT) in late pregnancy: challenges in management and review of literature

2020 ◽  
Vol 13 (12) ◽  
pp. e237970
Author(s):  
Elizabeth Ande ◽  
Silky Jain ◽  
Schahrazed Rouabhi ◽  
Wai Yoong
Keyword(s):  
Elective Caesarean Section ◽  
Mucinous Cystadenoma ◽  
Late Pregnancy ◽  
Ovarian Tumour ◽  
Serous Cystadenoma ◽  
Reproductive Age ◽  
Third Trimester ◽  
Borderline Ovarian Tumour ◽  
Younger Women ◽  
Ovarian Tumours

This case report describes a right-sided borderline ovarian tumour diagnosed unexpectedly following suspected torsion in the third trimester of pregnancy. The patient had had a right mucinous cystadenoma and left serous cystadenoma in her previous pregnancy and underwent bilateral ovarian cystectomy at the time of her first elective caesarean section. The management of borderline ovarian tumours is generally difficult in younger women of reproductive age and is made more complex by pregnancy. The authors share the challenges of managing this condition in pregnancy together with a review of the literature.

scholarly journals Clinicopathological analysis of ovarian tumors: a two year retrospective study

2019 ◽  
Vol 8 (8) ◽  
pp. 3015
Author(s):  
Kanika Chandra ◽  
Neetu Arora
Keyword(s):  
Age Distribution ◽  
Germ Cell Tumors ◽  
Ovarian Tumour ◽  
Serous Cystadenoma ◽  
Good Prognosis ◽  
Ovarian Tumors ◽  
Malignant Tumours ◽  
Ovarian Tumours ◽  
Heterogeneous Neoplasm ◽  
Risk Of Malignancy

Background: Ovarian tumours are a heterogeneous neoplasm with a varied clinical, morphological and histological feature. Increasing mortality rate due to ovarian cancers has been reported in recent years. Ovarian tumours in post-menopausal females have high risk of malignancy and it has a very poor outcome. The aim and objective of this study was to determine clinical and histopathological spectrum and the frequency and age distribution of various ovarian tumors.Methods: It is a retrospective observational study of patients with ovarian tumors in the department of obstetrics and gynecology, SGRRI of Medical Health & Sciences and Hospital from January 2016 to December 2017 in a total number of 86 patients. All specimens were sent to pathology department and categorised according to WHO  hispathological classification.Results: Out of 86 cases examined, 64 cases were benign (74.4%), 3 cases were borderline (3.4%) and 19 cases were malignant (22.2%). Majority of the ovarian tumors (73.4%) were seen in the age group of 20 to 50 years. Most commonly encountered benign ovarian tumour was serous cystadenoma (58.1%). Surface epithelial tumors were the commonest tumors (64%) followed by germ cell tumors (29%).Conclusions: A variety of benign and malignant tumours of ovary were reported in this study. Early diagnosis and appropriate treatment of ovarian neoplasms favour the good prognosis. Most common benign tumour encountered in this study was serous cystadenoma.

scholarly journals Preoperative Differentiation of Benign and Malignant Non-epithelial Ovarian Tumors: Clinical Features and Tumor Markers

2020 ◽  
Vol 42 (09) ◽  
pp. 555-561
Author(s):  
Tiago Augusto Gomes ◽  
Elizabeth Aparecida Campos ◽  
Adriana Yoshida ◽  
Luís Otavio Sarian ◽  
Liliana Aparecida Lucci de Angelo Andrade ◽  
...  
Keyword(s):  
Germ Cell ◽  
Clinical Features ◽  
Germ Cell Tumors ◽  
Serum Levels ◽  
Cell Tumor ◽  
Ovarian Tumors ◽  
Stromal Tumors ◽  
Fertility Sparing ◽  
Sex Cord Stromal Tumors ◽  
Sex Cord Stromal Tumor

Abstract Objective To evaluate the role of clinical features and preoperative measurement of cancer antigen 125 (CA125), human epididymis protein (HE4), and carcinoembryonic antigen (CEA) serum levels in women with benign and malignant non-epithelial ovarian tumors. Methods One hundred and nineteen consecutive women with germ cell, sex cord-stromal, and ovarian leiomyomas were included in this study. The preoperative levels of biomarkers were measured, and then surgery and histopathological analysis were performed. Information about the treatment and disease recurrence were obtained from the medical files of patients. Results Our sample included 71 women with germ cell tumors (64 benign and 7 malignant), 46 with sex cord-stromal tumors (32 benign and 14 malignant), and 2 with ovarian leiomyomas. Among benign germ cell tumors, 63 were mature teratomas, and, among malignant, four were immature teratomas. The most common tumors in the sex cord-stromal group were fibromas (benign) and granulosa cell tumor (malignant). The biomarker serum levels were not different among benign and malignant non-epithelial ovarian tumors. Fertility-sparing surgeries were performed in 5 (71.4%) women with malignant germ cell tumor. Eleven (78.6%) patients with malignant sex cord-stromal tumors were treated with fertility-sparing surgeries. Five women (71.4%) with germ cell tumors and only 1 (7.1%) with sex cord-stromal tumor were treated with chemotherapy. One woman with germ cell tumor recurred and died of the disease and one woman with sex cord-stromal tumor recurred. Conclusion Non-epithelial ovarian tumors were benign in the majority of cases, and the malignant cases were diagnosed at initial stages with good prognosis. The measurements of CA125, HE4, and CEA serum levels were not useful in the preoperative diagnosis of these tumors.

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