scholarly journals Gastric Electrical Stimulation for the Treatment of Obesity: From Entrainment to Bezoars—A Functional Review

2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Martin P. Mintchev

Growing worldwide obesity epidemic has prompted the development of two main treatment streams: (a) conservative approaches and (b) invasive techniques. However, only invasive surgical methods have delivered significant and sustainable benefits. Therefore, contemporary research exploration has focused on the development of minimally invasive gastric manipulation methods featuring a safe but reliable and long-term sustainable weight loss effect similar to the one delivered by bariatric surgeries. This antiobesity approach is based on placing external devices in the stomach ranging from electrodes for gastric electrical stimulation to temporary intraluminal bezoars for gastric volume displacement for a predetermined amount of time. The present paper examines the evolution of these techniques from invasively implantable units to completely noninvasive patient-controllable implements, from a functional, rather than from the traditional, parametric point of view. Comparative discussion over the available pilot and clinical studies related to gastric electrical stimulation outlines the promises and the fallacies of this concept as a reliable alternative anti-obesity strategy.

2000 ◽  
Vol 95 (9) ◽  
pp. 2447-2447 ◽  
Author(s):  
Thomas L. Abell ◽  
Jean Luo ◽  
Hani M. Rashed ◽  
Paula Eaton ◽  
Guy Voller ◽  
...  

Endoscopy ◽  
2020 ◽  
Vol 52 (05) ◽  
pp. C5-C5
Author(s):  
Shanshan Shen ◽  
Hui Luo ◽  
Cicily Vachaparambil ◽  
Parit Mekaroonkamol ◽  
Mohamed M. Abdelfatah ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
pp. 109-114
Author(s):  
Elżbieta Hanna Szafranko

AbstractAny building construction undertaking is inseparable from the environment in which it will be executed. Among all buildings, the most difficult ones from the point of view of nature protection are those which have been classified as having a considerable impact on the environment. Roads and road infrastructure are a particular case. Construction of roads or railroads and their subsequent long-term use lead to many changes in the environment. When planning such building projects, it is recommended to develop variant solutions in order to choose the one that would be least harmful to the environment, and then to submit them to an objective assessment. To facilitate the selection of an optimal solution, assessment indicators are developed. However, it needs to be remembered that a factor perceived as a negative one in the immediate assessment might generate positive consequences on a broader scale and vice versa. Hence, an assessment of the impacts on the environment caused by building projects should be viewed in the context of indirect (global) and direct (local) effects. This article will present a model analysis of the impacts caused by a fragment of a road, including local and global effects measured by the indicator method. This method has been developed by the author of this article, who believes that it enables the user to make a complex analysis, while the graphic presentation it involves, discussed in the conclusions to this paper, helps to decide easily which factors are decisive in the final assessment of the analysed project.


2020 ◽  
Vol 21 (17) ◽  
pp. 6056
Author(s):  
Barbara Ghinassi ◽  
Angela Di Baldassarre ◽  
Gianmaria D’Addazio ◽  
Tonino Traini ◽  
Mauro Andrisani ◽  
...  

The health of peri-implant soft tissues is important for the long-term success rate of dental implants and the surface topography is pivotal in influencing it. Thus, the aim of this study was to evaluate, in human patients, the inflammatory mucosal microenvironment in the tissue surrounding a new, nanoscale, laser-treated healing abutment characterized by engineered nanopores versus a standard machined-surface. Analyses of anti- and pro-inflammatory markers, cytokeratins, desmosomal proteins and scanning electron microscopy were performed in 30 soft-tissue biopsies retrieved during second-stage surgery. The results demonstrate that the soft tissue surrounding the laser-treated surface was characterized by a lower grade of inflammation than the one facing the machined-surface, which, in turn, showed a disrupted epithelium and altered desmosomes. Moreover, higher adhesion of the epithelial cells on the laser-treated surface was detected compared to the machined one. In conclusion, the laser-treated surface topography seems to play an important role not only in cell adhesion, but also on the inflammatory makers’ expression of the soft tissue microenvironment. Thus, from a clinical point of view, the use of this kind of topography may be of crucial importance not only on healing abutments but also on prosthetic ones.


2017 ◽  
Vol 152 (5) ◽  
pp. S729 ◽  
Author(s):  
Thomas Abell ◽  
Archana Kedar ◽  
Abigail Stocker ◽  
Karen Beatty ◽  
Lindsay McElmurray ◽  
...  

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