Boric Acid Catalyzed Convenient Synthesis of Benzimidazoles in Aqueous Media

Synthesis of benzimidazoles has been developed by theo-phenylenediamine with aldehydes using boric acid an efficient catalyst under mild reaction conditions in aqueous media. The product is applicable to aryl and heteroaryl aldehydes. This reaction led to the formation of benzimidazoles new derivatives in good yields. The FT-IR,19F-NMR,1H-NMR,13C-NMR spectra and elemental analysis confirm the structure of compounds.

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Thermo-mechanical and surface properties of POSS reinforced structurally different diamine cured epoxy nanocomposites

RSC Advances ◽

10.1039/c4ra06211f ◽

2014 ◽

Vol 4 (85) ◽

pp. 45433-45441 ◽

Cited By ~ 21

Author(s):

K. Sethuraman ◽

P. Prabunathan ◽

M. Alagar

Keyword(s):

Bisphenol A ◽

Surface Properties ◽

Nmr Spectra ◽

Epoxy Nanocomposites ◽

H Nmr ◽

Ft Ir ◽

C Nmr

In the present study three structurally different diamines namely bisphenol-A based ether diamine, octane diol based ether diamine, and capron based diamine were synthesized and characterized using FT-IR, 1H-NMR and 13C-NMR spectra.

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Synthesis of New Imidazolidine and Tetrahydropyrimidine Derivatives

Advances in Chemistry ◽

10.1155/2014/834641 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Hamid Beyzaei ◽

Reza Aryan ◽

Zahra Keshtegar

Keyword(s):

Ring Opening ◽

Reaction Times ◽

Reaction Conditions ◽

Ir Spectrometry ◽

H Nmr ◽

Chemical Structures ◽

Thioamide Group ◽

Solvent Free Conditions ◽

Ft Ir ◽

C Nmr

Synthesis of new imidazolidine and tetrahydropyrimidine derivatives 3a, b and 4a–c as cyclic 1,3-diamines under two reaction conditions (A and B) is described. Under reaction conditions-A, a suspension of (E)-2-cyano-2-(oxazolidin-2-ylidene)ethanethioamide 1 (1 eq.) and diaminoalkanes 2a–e (2 eq.) in absolute ethanol is heated under reflux for 16–22 h to afford 3a, b and 4a–c. Alternatively, under reaction conditions-B, a solution of thioamide 1 (1 eq.) in diaminoalkanes 2a–e (3 eq.) is stirred under solvent-free conditions at room temperature for 3 days to give desired products. Reaction conditions-A for having higher yields, shorter reaction times, and required less diamines is more effective than reaction conditions-B. Oxazolidine ring opening is observed by reacting compound 1 with all of the diamines 2a–e, but the thioamide group only reacts with nonbulky diamines 2a, b. The chemical structures of novel compounds were confirmed by 1H NMR, 13C NMR, elemental analysis, and FT-IR spectrometry.

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Microwave-Assisted Hydrogenation of Codeine in Aqueous Media

ISRN Organic Chemistry ◽

10.5402/2012/104975 ◽

2012 ◽

Vol 2012 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

F. Taktak ◽

I. Bulduk

Keyword(s):

Aqueous Solution ◽

Aqueous Media ◽

One Pot ◽

H Nmr ◽

Microwave Assisted ◽

Analysis Technique ◽

Purity Analysis ◽

Ft Ir ◽

Elemental Analysis Technique ◽

C Nmr

An efficient one-pot microwave-assisted hydrogenation of codeine was achieved in aqueous solution. This technique is simple, fast, environmentally friendly, and highly efficient. Structure of produced dihydrocodeine was approved by using FT-IR, 1H NMR, 13C NMR, EIMS, and elemental analysis technique. Its purity analysis was performed by using HPLC and assay analysis was performed by using potentiometric titration methods.

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ChemInform Abstract: Boric Acid Catalyzed Convenient Synthesis of 2-Amino-3,5-dicarbonitrile-6-thio-pyridines in Aqueous Media.

ChemInform ◽

10.1002/chin.201025122 ◽

2010 ◽

Vol 41 (25) ◽

pp. no-no

Author(s):

Pravin V. Shinde ◽

Swapnil S. Sonar ◽

Bapurao B. Shingate ◽

Murlidhar S. Shingare

Keyword(s):

Boric Acid ◽

Aqueous Media ◽

Convenient Synthesis ◽

Acid Catalyzed

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Para toluenesulfonic acid-catalyzed one-pot, three-component synthesis of benzo[5,6]chromeno[3,2-c]quinoline compounds in aqueous medium

Heterocyclic Communications ◽

10.1515/hc-2020-0128 ◽

2021 ◽

Vol 27 (1) ◽

pp. 90-99

Author(s):

Naser Sadeghpour Orang ◽

Hadi Soltani ◽

Mehdi Ghiamirad ◽

Mehdi Ahmadi Sabegh

Keyword(s):

Thermal Conditions ◽

Reaction Conditions ◽

One Pot ◽

Mass Spectral ◽

H Nmr ◽

Toluenesulfonic Acid ◽

Ft Ir ◽

High Yields ◽

Arylglyoxal Monohydrates ◽

C Nmr

Abstract A new series of benzo[5,6]chromeno[3,2-c]quinoline derivatives were successfully synthesized using various arylglyoxal monohydrates, quinoline-2,4-dione, and β-naphthol in H2O:EtOH (2:1) as a green solvent in the presence of catalytic amounts p-toluenesulfonic acid as a mild catalyst under reflux conditions with high yields (83–92%). The reaction conditions were optimized in different solvents at variable thermal conditions, and the optimized reaction condition for this synthesis has been reported. The structures of all new products were defined by 1H-NMR, 13C-NMR, FT-IR, mass spectral data, and HRMS.

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Synthesis, Characterization and Antibacterial Activity of Schiff Bases and their Metal Complexes Derived from 4-Acyl-1-phenyl-3-methyl-2-pyrazolin-5-ones and 2-Amino-4(4'-methylphenyl)-thiazole

E-Journal of Chemistry ◽

10.1155/2010/163264 ◽

2010 ◽

Vol 7 (4) ◽

pp. 1396-1406 ◽

Cited By ~ 9

Author(s):

A. S. Thakar ◽

K. K. Singh ◽

K. T. Joshi ◽

A. M. Pancholi ◽

K. S. Pandya

Keyword(s):

Antibacterial Activity ◽

Schiff Bases ◽

Elemental Analysis ◽

Mass Spectra ◽

Nmr Spectra ◽

Electrical Conductance ◽

H Nmr ◽

Infrared Spectral ◽

Ft Ir ◽

C Nmr

4-Acyl-1-phenyl-3-methyl-2-pyrazolin-5-ones condensed with 2-amino-4(4'-methylphenyl)-thiazole to form Schiff base. These Schiff bases from complexes of type ML22H2O (M=Mn, Fe, Co, Ni and Cu). Elemental analysis, magnetic susceptibility, electrical conductance, electronic and Infrared spectral data suggested octahedral structure for the complexes. All the compounds were tested for their antibacterial activity. The result indicates that the growth of the tested organism was inhibited by most of the compounds. These Schiff bases are characterized by elemental analysis, mass spectra,1H-NMR spectra,13C NMR spectra and FT IR spectra.

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Synthesis and NMR Studies of Some Steroidal Isoxazoles

Zeitschrift für Naturforschung B ◽

10.1515/znb-1992-0620 ◽

1992 ◽

Vol 47 (6) ◽

pp. 891-897 ◽

Cited By ~ 3

Author(s):

Sergio Giacopello ◽

Mónica E. Deluca ◽

Alicia M. Seldes

Keyword(s):

Nmr Spectra ◽

Two Dimensional ◽

Model Compounds ◽

Nmr Studies ◽

Reaction Conditions ◽

Related Model ◽

H Nmr ◽

Short Synthesis ◽

Nmr Methods ◽

C Nmr

A short synthesis of 17α-pregna-2,4-dien-[2,3-d]isoxazol-17β-ol (1) is described using mild reaction conditions and with a high overall yield. The equilibrium between keto-enolic forms has been studied by 1H NMR methods. Complete assignments of all the resonances in the 1H and 13C NMR spectra of Danazol have been made using a variety of one and two-dimensional correlation methods. 13C NMR spectra of all the intermediate and related model compounds were also assigned.

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Convenient Synthesis of the 2,5-di-Substituted 1,3,4-Oxadiazole Derivatives under Microwave

International Letters of Chemistry Physics and Astronomy ◽

10.18052/www.scipress.com/ilcpa.30.159 ◽

2014 ◽

Vol 30 ◽

pp. 159-166

Author(s):

Dipti L. Namera ◽

Umed C. Bhoya

Keyword(s):

Experimental Data ◽

Cinnamic Acid ◽

Elemental Analysis ◽

H Nmr ◽

Microwave Assisted ◽

Convenient Synthesis ◽

Oxadiazole Derivatives ◽

Ft Ir ◽

Microwave Assisted Method ◽

C Nmr

We have reported some novel 1,3,4-oxadiazole synthesized by conventional method as well as microwave assisted method. The reaction of different substituted cinnamic acid 2a-o with 2-(4-chlorophenyl) acetohydrazide by using phosphoric anhydride as catalyst, yielded a series of 2,5-di-substituted 1,3,4-oxadiazole 6a-o. The structures of all synthesized compounds are well characterized by Mass, FT-IR, 1H NMR, 13C NMR and elemental analysis. After obtaining experimental data regarding the yield and the time taken for the synthesis by both the methods, conventional and microwave assisted method, it was proved that the microwave assisted method is convenient for synthesis of this type of 2,5-di-substituted 1,3,4-oxadiazole 6a-o.

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Synthesis and Nitration of 7-Hydroxy-4-Methyl Coumarin via Pechmann Condensation Using Eco-Friendly Medias

International Letters of Chemistry Physics and Astronomy ◽

10.18052/www.scipress.com/ilcpa.69.66 ◽

2016 ◽

Vol 69 ◽

pp. 66-73 ◽

Cited By ~ 7

Author(s):

Fadia Al Haj Hussien ◽

Mohammad Keshe ◽

Khaled Alzobar ◽

Joumaa Merza ◽

Ayman Karam

Keyword(s):

Biological Activity ◽

Coumarin Derivatives ◽

Melting Points ◽

Efficient Catalyst ◽

Amberlyst 15 ◽

H Nmr ◽

Pechmann Condensation ◽

Solvent Free Conditions ◽

Ft Ir ◽

C Nmr

A nitro coumarin derivatives has been synthesized via nitration of 7-hydroxy-4-methyl coumarin wich was synthesized via Pechmann condensation resorcinol with a β-ketoester using Amberlyst-15 as a green and efficient catalyst and by caring out the reaction of resorcinol and ethyl acetoacetate (with 1: 1 mol ratio) in the presence of 0.2 g of Amberlyst-15 at 110°C under solvent-free conditions. These nitro coumarin derivatives have biological activity and momentousness in the industrial fields. The purified products were measured the melting points and characterized by spectral methods: FT-IR,1H-NMR ,13C-NMR.

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