scholarly journals A Case of Almost Painless Herpes Zoster Presenting with Symptoms of Cystitis, Penile Numbness, and Acute Vestibular Failure

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Hussain Al-Sardar
Keyword(s):  
Herpes Zoster ◽  
Peripheral Nerves ◽  
The Elderly ◽  
Tricyclic Antidepressant ◽  
Risk Of Infection ◽  
Significant Morbidity ◽  
Unilateral Lesion ◽  
Cutaneous Eruption ◽  
Varicella Zoster ◽  
Chicken Pox

Herpes zoster (shingles) is an acute, painful, vesicular, and cutaneous eruption caused by varicella zoster virus, the same virus which causes chicken pox. It is due to the reactivation of the virus which remains dormant in sensory ganglions following chicken pox. It is usually confined to a single dermatome but may involve 2-3 dermatomes. Typically, it is a unilateral lesion which can affect both cranial and peripheral nerves. It is usually a self-limiting disease; however, it may cause significant morbidity especially in the elderly. It is more common in older people and individuals with immunocompromised conditions. Antiviral drugs can shorten the duration and the severity of the illness and need to be started as soon as possible after the appearance of the rash. Gabapentin and tricyclic antidepressant are effective in postherpetic neuralgia. Vaccine can reduce the risk of infection and its associated pain. Typically, it occurs once in a lifetime, but some individuals may have more than one episode.

scholarly journals Herpes zoster (Shingles)

2018 ◽  
Vol 60 (4) ◽  
pp. 28-30 ◽  
Author(s):  
M. H. Motswaledi
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
The Elderly ◽  
Spinal Ganglia ◽  
Specific Cell ◽  
Varicella Zoster ◽  
Chicken Pox ◽  
Physical Trauma ◽  
Age Related ◽  
Thoracic Spinal

Herpes zoster or Shingles is caused by varicella-zoster virus (VZV), the same virus that causes chicken-pox (varicella).Primary infection with varicella-zoster virus causes chicken-pox (varicella), then the virus persists in nerve ganglia of sensory but rarely motor nerves, in a latent stage.If the virus gets reactivated it causes herpes zoster, which presents as painful vesicles following a dermatome. It is more common in the elderly and the immunocompromised.Herpes zoster is a common skin and mucous membrane disease caused by reactivation of latent varicella zoster virus, which had lodged previously in nerve ganglia.Trigeminal nerve nuclei and thoracic spinal ganglia are the most commonly affected.Reactivation of latent varicella-zoster virus can be triggered by old age, that is why herpes zoster is common in the elderly, above 60 years of age. This is due to age related decline in specific cell mediated immune response to VZV. Other triggering factors are malignancies malnutrition, emotional stress, physical trauma, chronic diseases like diabetes mellitus and immunosuppression from drugs and HIV.¹,²

scholarly journals Sudden, Intense, Unexpected and Negative Emotions are a Reactivation Factor of Herpes Zoster

2019 ◽  
Vol 2 (1) ◽  
pp. 21-24
Author(s):  
Patricia Lago-López ◽  
◽  
María José Parrado-Alonso ◽  
Beatriz Villar-Fernández ◽  
Teresa Isabel Calheiros-Cruz ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Negative Emotions ◽  
Varicella Zoster ◽  
Chicken Pox

Herpes zoster is caused by a reactivation of residual varicella zoster virus (VZV) which remains latent in the nerve ganglia, after primary chicken pox. Zoster or girdle refers to occurrence of the disease in a segmental distribution.

scholarly journals Case Report: When Shingles Disrupts Bladder Function

2020 ◽  
Vol 3 (1) ◽  
pp. 95-97
Author(s):  
Aaron Campeas ◽  
◽  
Eric J. Basile ◽  
◽  
◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Dorsal Root ◽  
Rare Complication ◽  
Bladder Function ◽  
Buttock Pain ◽  
Varicella Zoster ◽  
Chicken Pox ◽  
Double Stranded Dna ◽  
Left Buttock ◽  
Vesicular Rash

Varicella Zoster (shingles) virus is a double stranded DNA in the Herpesviridae family that can present as both chicken pox and as shingles. The virus enters through the respiratory system, replicating in the nasopharynx, and causes a viremia upon primary infection. Varicella Zoster spreads to other organs and often lies dormant in the dorsal root ganglion. Reactivation of the virus is more common in older or immunocompromised patients and often presents as a painful vesicular rash in a unilateral dermatomal distribution with possible concurrent radiculopathy. A rare complication of herpes zoster is urinary dysfunction. We report a case of a 42-year-old patient diagnosed with herpes zoster whose primary complaint was left buttock pain and a maculovesicular rash in the S2-S4 dermatomal distribution. She was prescribed Valacyclovir and began to experience urinary retention two days after starting the medication.

scholarly journals Herpes zoster in the radial nerve distribution in an 8 years old healthy child-a case report

2017 ◽  
Vol 5 (3) ◽  
pp. 1123
Author(s):  
Hala Edris ◽  
Abdullah Abualiat ◽  
Ayed Al Mordy
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Radial Nerve ◽  
Dorsal Root ◽  
Primary Infection ◽  
The Body ◽  
Varicella Zoster ◽  
Chicken Pox ◽  
Nerve Ganglion ◽  
Common Area

Varicella zoster is an omnipresent virus which commonly affects childhood as chicken pox. Although the primary infection is self-limiting and seldom severe, the virus remains dormant in the body. The virus resides in the dorsal root or cranial nerve ganglion and reactivation may occur years later as herpes zoster or "Shingles". Herpes zoster (HZ) can occur at any age but is rare in childhood and adolescents. Old aged and immunosuppressed subjects are at risk for developing the disease. The most common area involved in HZ is the trunk (dermatomes innervated by the thoracic nerves) and rarely presents exclusively in the upper extremity. We report a case of HZ isolated to the radial nerve distribution in a healthy 8 years boy. The reported case reveals the importance of considering zoster infection in young age, or uncommon sites when evaluating the onset of pain in a dermatomal distribution specially if associated with vesiculobullous rash.

scholarly journals Herpes Zoster Onset 9 Years After First Varicella Zoster Vaccination in an 11-year-old Child - A Case Report

2019 ◽  
Vol 15 (4) ◽  
pp. 265-267
Author(s):  
Kerasia-Maria Plachouri ◽  
Despoina Gkentzi ◽  
Anastasia Varvarigou ◽  
Sophia Georgiou ◽  
Gabriel Dimitriou
Keyword(s):  
Herpes Zoster ◽  
Elderly Population ◽  
Pediatric Patients ◽  
Varicella Vaccine ◽  
The Elderly ◽  
Published Data ◽  
Healthy Children ◽  
Case Presentation ◽  
Varicella Zoster ◽  
National Immunization

Background: Herpes zoster (HZ) tends to affect the elderly population and immunocompromised younger patients. However, HZ cases in healthy children have also been reported. Objective: This paper is a reminder to physicians, that Herpes Zoster can still be present in children, even in the era after the development of the varicella vaccine and its introduction in the national immunization programs globally. Methods: We present the case of an immunocompetent 11-year old vaccinated male patient, who developed a HZ infection. The child had received two doses of the VZV vaccination (Varivax®), nine years (first dose) and six years (second dose) prior to the infection. Results: Together with the case presentation, we summarize in this report the most recent published data, concerning the HZ prevalence in healthy varicella zoster vaccinated children. Conclusion: Vaccinated pediatric patients are not completely free of risk concerning HZ. Physicians, especially pediatricians and dermatologists, should be alert in order to recognize and treat HZ early, so as to avoid further complications.

scholarly journals AGE PECULIARITIES OF HERPES ZOSTER CLINIC

2019 ◽  
Vol 24 (4) ◽  
pp. 156-159
Author(s):  
D. M. Polyakova ◽  
V. V. Nikiforov ◽  
Murad Z. Shakhmardanov
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Clinical Symptoms ◽  
Clinical Course ◽  
The Elderly ◽  
Viral Disease ◽  
Economic Conditions ◽  
Virus Diagnosis ◽  
Varicella Zoster ◽  
Potential Risk Factors

Herpes zoster is a viral disease that occurs as a result of reactivation of Varicella zoster virus and is characterized by damage to the skin, nervous tissue. This disease develops as a secondary endogenous infection in individuals who have previously had chickenpox. Potential risk factors for herpes zoster are old age, the presence in patients of cancer and / or hematological diseases, diabetes, HIV infection, drug immunosuppression. Changes in socio-economic conditions are accompanied by pathomorphosis of diseases. This fully applies to the infection caused by Varicella zoster virus. Diagnosis of herpes zoster in the prodromal period is difficult, since there are no characteristic bubble rashes. Late diagnosis leads to delayed medical care. The clinical differences of herpes zoster in 78 patients of different age categories were studied: up to 60 years, and after 60 years. The terms of diagnosis, duration of prehospital and hospital stages, clinical symptoms, presence of concomitant pathology and complications were studied. It was shown that the diagnosis of herpes zoster at the prehospital stage was established only in half of the patients, which led to late hospitalization and may have contributed to the development of complications. Among the features of the clinical course, a lower incidence of concomitant pathology and adequate immunoreactivity were noted in persons under the age of 60 years, compared with patients over the age of 60 years. It is assumed that the reactivation of Varicella zoster virus, which is associated in the elderly with immunosuppression against the background of combined chronic somatic pathology, in young people may be due to other reasons, among which may be, including the features of the pathogen.

Antiviral Therapy in Herpes Zoster: A Review

1997 ◽  
Vol 8 (6_suppl) ◽  
pp. 37-42 ◽  
Author(s):  
J Marley
Keyword(s):  
Chronic Pain ◽  
Herpes Zoster ◽  
Antiviral Therapy ◽  
Antiviral Agents ◽  
The Elderly ◽  
Post Herpetic Neuralgia ◽  
Latent Form ◽  
Varicella Zoster ◽  
Better Than ◽  
The Continuum

Herpes zoster is a disease caused by reactivation of the latent form of the varicella zoster virus (VZV). It is usually seen in adults, occurring mainly in the elderly. The acute phase of the disease is characterized by a rash, which is typically accompanied by pain. In some patients the pain may persist after the rash has healed, and may last for many months or years. Three antiviral agents are currently available to treat herpes zoster: aciclovir, its prodrug valaciclovir, and famciclovir. All three are effective in accelerating healing of the rash, and reducing the patient's period of infectivity. These antiviral agents also impact on the chronic pain associated with herpes zoster but appear to differ in their efficacy. Two different measures of chronic pain have been used in clinical studies: post-herpetic neuralgia (PHN) which refers to the pain occurring after the rash has healed, and zoster-associated pain (ZAP), defined as the continuum of pain occurring after the onset of herpes zoster (i.e. making no distinction between acute pain and PHN). Famciclovir has been shown to significantly reduce the risk and duration of PHN in patients over 50 years old. In another study famciclovir was shown to be significantly more effective than aciclovir in relieving ZAP when treatment was taken within 48 h of the onset of herpes zoster. Valaciclovir was also found to be better than aciclovir in reducing the duration of ZAP, but it is unclear whether this improvement over aciclovir also applied to PHN. Elderly patients therefore benefit from antiviral therapy, which should be initiated as early as possible, and can significantly reduce the risk and duration of the chronic pain associated with herpes zoster.

Immunology of Varicella Immunization in the Elderly

2000 ◽  
Vol 34 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Carla K Raeder ◽  
Mary S Hayney
Keyword(s):  
Immune Response ◽  
Herpes Zoster ◽  
English Language ◽  
Varicella Vaccine ◽  
The Elderly ◽  
Cell Mediated Immunity ◽  
Elderly Individuals ◽  
Medline Search ◽  
Varicella Zoster ◽  
Age Related

OBJECTIVE: To review the varicella-zoster virus (VZV) and herpes zoster disease and to summarize published reports on the use of the live-attenuated varicella zoster vaccine to enhance cell-mediated immunity in elderly individuals. DATA SOURCE: A MEDLINE search (1966–August 1999) for English-language clinical studies and review articles pertaining to VZV and the live-attenuated varicella vaccine was conducted; references obtained from these publications were subsequently reviewed for additional relevant articles. STUDY SELECTION AND DATA EXTRACTION: Representative clinical trials were summarized and relevant information was selected to assist in the understanding of VZV, the subsequent immune response, and the live-attenuated varicella vaccine. DATA SYNTHESIS: The physiologic, age-related decline in VZV cell–mediated immunity has been shown to be restored on administration of live-attenuated varicella vaccine. Various studies report serum anti-VZV antibody concentrations, and production of interferon-gamma were increased following vaccination. Concentrations subsequently returned to baseline one year after vaccination. Increase in responder cell frequency, a measure of cell-mediated immunity, has been reported to last up to four years after vaccination, at concentrations similar or superior to those observed following herpes zoster. CONCLUSIONS: Enhancement of cell-mediated immune response in elderly individuals through vaccination with live-attenuated varicella vaccine is a possible measure to protect this population from herpes zoster and to attenuate its complications. A summary of immunogenicity studies to identify the immune response to live-attenuated varicella vaccine in the elderly is presented. The absolute clinical significance, as well as appropriate administration guidelines of this prophylactic intervention, will become evident following forthcoming large, masked, placebo-controlled trials.

scholarly journals AGE PECULIARITIES OF HERPES ZOSTER CLINIC

2019 ◽  
Vol 24 (4) ◽  
pp. 156-159
Author(s):  
D. M. Polyakova ◽  
V. V. Nikiforov ◽  
Murad Z. Shakhmardanov
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Clinical Symptoms ◽  
Clinical Course ◽  
The Elderly ◽  
Viral Disease ◽  
Economic Conditions ◽  
Virus Diagnosis ◽  
Varicella Zoster ◽  
Potential Risk Factors

Herpes zoster is a viral disease that occurs as a result of reactivation of Varicella zoster virus and is characterized by damage to the skin, nervous tissue. This disease develops as a secondary endogenous infection in individuals who have previously had chickenpox. Potential risk factors for herpes zoster are old age, the presence in patients of cancer and / or hematological diseases, diabetes, HIV infection, drug immunosuppression. Changes in socio-economic conditions are accompanied by pathomorphosis of diseases. This fully applies to the infection caused by Varicella zoster virus. Diagnosis of herpes zoster in the prodromal period is difficult, since there are no characteristic bubble rashes. Late diagnosis leads to delayed medical care. The clinical differences of herpes zoster in 78 patients of different age categories were studied: up to 60 years, and after 60 years. The terms of diagnosis, duration of prehospital and hospital stages, clinical symptoms, presence of concomitant pathology and complications were studied. It was shown that the diagnosis of herpes zoster at the prehospital stage was established only in half of the patients, which led to late hospitalization and may have contributed to the development of complications. Among the features of the clinical course, a lower incidence of concomitant pathology and adequate immunoreactivity were noted in persons under the age of 60 years, compared with patients over the age of 60 years. It is assumed that the reactivation of Varicella zoster virus, which is associated in the elderly with immunosuppression against the background of combined chronic somatic pathology, in young people may be due to other reasons, among which may be, including the features of the pathogen.

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