scholarly journals Higher Mobility Scores in Patients with Cystic Fibrosis Are Associated with Better Lung Function

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Aneesha Thobani ◽  
Jessica A. Alvarez ◽  
Shaina Blair ◽  
Kaila Jackson ◽  
Eric R. Gottlieb ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Lung Function ◽  
Observational Study ◽  
Outcome Measures ◽  
Prospective Cohort ◽  
Care Center ◽  
Life Space ◽  
Specialized Care ◽  
One Year

Objective.The purpose of this study was to determine whether mobility and physical activity were associated with lung function in adults with cystic fibrosis (CF).Design.This was a prospective cohort observational study in an urban, academic, specialized care center. Participants were ambulatory, nonhospitalized adults with CF.Main Outcome Measures.Mobility was assessed monthly by the Life-Space Assessment (LSA) questionnaire and quarterly by pedometer. Lung function was assessed by spirometry.Results.Twenty-seven subjects participated. Subjects recorded mean pedometer steps of 20,213 ± 11,331 over three days and FEV1% predicted of 77.48% ± 22.60% over one year. The LSA score at enrollment was correlated with initial pedometer steps (r=0.42andP=0.03), and mean LSA score over one year was correlated with mean number of steps (r=0.51andP=0.007). LSA mobility and pedometer scores were correlated with FEV1% predicted at enrollment and throughout the study.Conclusions.Mobility and physical activity measured by LSA questionnaire and pedometer are positively associated with lung function in adults with CF. This study confirms the importance of mobility and physical activity and supports the utility of a simple office-based questionnaire as a measure of mobility in adults with CF.

Physical Activity and Sedentary Behavior in Adults With Cystic Fibrosis: Association With Aerobic Capacity, Lung Function, Sleep, Well-Being, and Quality of Life

2021 ◽  
pp. respcare.09270
Author(s):  
Máire Curran ◽  
Audrey C Tierney ◽  
Brenda Button ◽  
Louise Collins ◽  
Lauren Kennedy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Cystic Fibrosis ◽  
Lung Function ◽  
Sedentary Behavior ◽  
Aerobic Capacity ◽  
Well Being

Physical activity participation by adults with cystic fibrosis: An observational study

Respirology ◽  
2015 ◽  
Vol 21 (3) ◽  
pp. 511-518 ◽  
Author(s):  
Narelle S. Cox ◽  
Jennifer A. Alison ◽  
Brenda M. Button ◽  
John W. Wilson ◽  
Judith M. Morton ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Observational Study ◽  
Physical Activity Participation ◽  
Activity Participation

Investigating the Measurement of Physical Activity and Associated Factors in Youth and Adults with Cystic Fibrosis

2021 ◽  
Author(s):  
◽  
Mayara S. Bianchim
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Lung Function ◽  
Vigorous Physical Activity ◽  
The Body ◽  
Machine Learning Algorithms ◽  
Cut Points ◽  
Measurement And Analysis ◽  
The Relationship ◽  
Crucial Part

Cystic Fibrosis (CF) is a multisystemic condition that affects almost every organ in the body, but especially the lungs. Regular physical activity (PA) can significantly slow disease progression and has become a crucial part of CF care. Previous research evaluating PA in CF has been hindered by the use of cut-points developed for healthy populations and the investigation of collinear movement behaviours as independent entities, both of which are likely to have confounded their findings and any subsequent inferences regarding associated health outcomes. Therefore, the overall aim of this thesis was to investigate the measurement and analysis of PA in those with CF. An initial systematic review provided recommendations for research calibrating accelerometry in paediatric clinical populations, highlighting that the pathophysiology of the condition must be accounted for and that the protocol should include a broad range of activities varying in intensity (Chapter 4). Subsequently, Chapter 5 developed and cross-validated raw acceleration CF-specific cut-points in youth which were then further assessed in Chapter 6, demonstrating that the CF-specific thresholds were associated with higher levels of moderate-to-vigorous physical activity (MVPA) and sedentary time (SED) and lower levels of light PA compared to generic cut-points. Furthermore, lung function was associated with light PA when using condition-specific thresholds. Further investigation of the relationship between PA and health in Chapter 7 found that reallocating time from sedentary to any other behaviour was beneficial for lung function, with the greatest improvements observed when SED was reallocated to sleep or MVPA. Finally, Chapter 8 developed and validated machine learning algorithms that achieved excellent accuracy to classify PA types and intensities in youth with CF. In conclusion, these findings significantly advance the assessment of PA, enhancing our understanding of the relationship between PA and health in CF and informing future condition-specific PA guidelines, care strategies and interventions.

Body image in COPD and its relation with physical activity levels, lung function and body composition: An observational study

2020 ◽  
Vol 14 (12) ◽  
pp. 1182-1190
Author(s):  
Ana Paula Coelho Figueira Freire ◽  
Aline Duarte Ferreira ◽  
Caroline Pereira Santos ◽  
Isabela Cristina Duarte Araújo ◽  
Juliana Souza Uzeloto ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Image ◽  
Body Composition ◽  
Lung Function ◽  
Observational Study ◽  
Activity Levels ◽  
Physical Activity Levels

scholarly journals Accumulating physical activity in at least 10-minute bouts predicts better lung function after 3-years in adults with cystic fibrosis

2018 ◽  
Vol 4 (2) ◽  
pp. 00095-2017 ◽  
Author(s):  
Narelle S. Cox ◽  
Jennifer A. Alison ◽  
Brenda M. Button ◽  
John W. Wilson ◽  
Judith M. Morton ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Lung Function

scholarly journals Assessment of Recovery From Geriatric Ankle Fracture Using The Life Space Mobility Assessment (LSA)

2017 ◽  
Vol 2 (3) ◽  
pp. 2473011417S0000
Author(s):  
Briggs Ahearn ◽  
Jason Bariteau ◽  
Danielle Mignemi ◽  
Claire Mueller ◽  
Stephanie Boden
Keyword(s):  
Outcome Measures ◽  
Ankle Fracture ◽  
Surgical Patients ◽  
Patient Specific ◽  
Visual Analogue Pain Scale ◽  
Life Space ◽  
Improved Outcomes ◽  
Sf 36 ◽  
One Year ◽  
Geriatric Ankle Fracture

Category: Trauma Introduction/Purpose: Ankle fractures are the third most common type of fracture seen in the elderly population and recent work has suggested that operative intervention may provide improved outcomes. Current outcome measures do not accurately assess true mobility in the geriatric population. In this study, we utilize the Life Space Assessment (LSA), a novel medical assessment survey which focuses specifically on how a patient functions within his/her environment following a medical event. This tool has not been previously utilized in orthopedic patients. We postulated that the LSA would provide improved assessment of these patients and help identify key differences in operative and non-operatively treated patients when compared to current outcome measures. Methods: This study was designed as a prospective observational study in which all geriatric patients age 65 and older with an ankle fracture were followed for one year from the time they presented for treatment. Treatment options of either non- operative or operative were determined by the attending physician on a patient specific basis. The patient was invited to participate in the study at the initial injury visit. The LSA was administered at the initial visit and 6 weeks, 3 months, 6 months and 12 months post injury/surgery. The SF-36 and Visual Analogue Pain Scale surveys were administered at 6 months and 12 months as a comparison. Survey scores were tallied and standard means were determined for each time point. Statistical analyses were performed to determine significance. Results: 26 patients met inclusion criteria and 20 were enrolled. 11 underwent surgery while 9 were treated non-operatively. The surgical LSA group scored 91.4 pre-injury and improved to 87.6 after 1 year which was near baseline (Graph #1). The non-op group recorded 80.88 pre-injury and only improved to 59.5 at 1 year. For the VAS, surgical patients reported pain of 2.2 and 1.75 at 6 and 12 months. Non-op patients recorded pain of 2.25 and 2.4 at 6 and 12 months. For SF-36 physical score, surgical patients recorded 57.6 and 75.8 at 6 and 12 months while non-op patients scored 53.3 and 59.43. SF-36 mental scores for the surgical group was 60.63 and 74.83 while non-op patients recorded 76.88 and 86.5 at 6 and 12 months. Conclusion: Operative patients returned to their baseline LSA while non-operative patients continued to have lower mobility at one year. All patients’ mobility was significantly limited for first three months. Surgical patients had less pain at 12 months compared to non-op. Surgical patients showed significant improvement in SF-36 physical scores from 6 months to 1 year while non-op patients had minimal improvement echoing our findings from LSA. The operative group had improved outcomes compared to non-op and this is reflected in both their LSA and SF- 36 scores. Further investigations are needed to determine optimal treatment paradigm for geriatric ankle fracture patients.

scholarly journals Reduced physical activity and weight gain are associated with an increase of depressive symptoms during the COVID-19 pandemic. A general practitioners’ prospective observational study

2021 ◽  
Vol 10 ◽  
pp. 204800402110477
Author(s):  
Simon Wernhart ◽  
Eberhard Weihe ◽  
Tienush Rassaf
Keyword(s):  
Physical Activity ◽  
Depressive Symptoms ◽  
Weight Gain ◽  
Observational Study ◽  
General Practitioners ◽  
Outcome Measures ◽  
Prospective Observational Study ◽  
Primary Outcome Measure ◽  
Secondary Outcome ◽  
Reduced Physical Activity

Objectives We aimed to assess associations between depressive symptoms, lifestyle, and somatic symptoms during the COVID-19 pandemic. Design A prospective, observational study using a self-designed questionnaire. Setting Three general practitioners’ (GP) offices in rural Germany. Participants 271 adult patients without manifest cardiovascular or pulmonary disease with (n = 82) and without (n = 189) hypertension reporting to our GP offices. Main outcome measures The reported increase of depressive symptoms (loneliness, sleeplessness, joylessness, listlessness) prior to the first documented case in Germany on 27.01.2020 (t0) as opposed to patients’ health perception during the Corona pandemic (t1) was the primary outcome measure. The secondary outcome measures were changes in physical activity (PA), dyspnea and angina in the two groups. Results Out of 271 patients (50.8 ± 16.8 years, 55.1% females), 1.5% were tested positive for COVID-19. Overall, listlessness (8.5%, p = 0.001), sleeplessness (5.2%, p = 0.001) and joylessness (4.2%, p = 0.003) were increased. Dyspnea significantly increased (9.2%, p < 0.001) and employment status worsened (6.5%, p < 0.001). There were significant associations between the increase of depressive symptoms, weight increase (p = 0.017), and reduction in physical activity (p = 0.046). However, after adjusting for age, hypertensive patients did not show more depressive symptoms (p = 0.704), dyspnea (p = 0.063) or angina (p = 0.432), nor was there any difference in PA (p = 0.906) compared to healthy individuals. Conclusions We demonstrate an association between the deterioration of depressive symptoms, weight gain, and reduced physical activity during COVID-19, both in hypertensives and healthy controls. Hypertension is no driver of symptom deterioration during the pandemic. The trial was registered in the German Clinical Trials Registry (DRKS00022157).

Complete versus Limited Endoscopic Sinus Surgery for Chronic Rhinosinusitis in Adults with Cystic Fibrosis

2020 ◽  
Vol 162 (4) ◽  
pp. 572-580 ◽  
Author(s):  
Daniel J. Lee ◽  
Christopher M. K. L. Yao ◽  
Jenna Sykes ◽  
Leena Rizvi ◽  
Elizabeth Tullis ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Function ◽  
Postoperative Period ◽  
Endoscopic Sinus Surgery ◽  
Hospital Admissions ◽  
Care Center ◽  
Sinus Surgery ◽  
Oral Antibiotic ◽  
Health Care Center ◽  
Pulmonary Exacerbations

Objective To examine the effects of the extent of endoscopic sinus surgery (ESS) on pulmonary health, including the pulmonary exacerbations and lung function in patients with cystic fibrosis (CF). Study Design Retrospective cohort study. Setting Tertiary health care center. Subjects and Methods A retrospective review of patients with CF who underwent ESS at St. Michael’s Hospital between 1999 and 2016 was performed. Two groups of patients were identified based on the surgical extent: (1) complete (maxillary antrostomy, complete ethmoidectomy, sphenoidotomy, and frontal sinusotomy) and (2) limited (any ESS that involved less than complete). Primary outcomes included the number of pulmonary exacerbations (the use of oral or intravenous [IV] antibiotics), number of hospital admissions and hospital days during a 2-year pre- and postoperative period, and pulmonary function outcomes during a 1-year pre- and postoperative period. Results There were 70 procedures (30 complete and 40 limited) among 57 patients. Baseline characteristics were similar between the groups. Complete ESS group had a significant reduction in the oral antibiotic use compared to the limited ESS group (median, –1.0 [interquartile range (IQR), –2 to 0] in complete vs 0 [IQR, –1 to 1] in limited, P = .028). There was no difference in the use of IV antibiotics, number and duration of admissions, or rate of lung function change between the 2 groups. Conclusion Complete ESS may reduce mild forms of pulmonary exacerbations as shown in the decreased use of oral antibiotics. Overall, ESS does not significantly modify pulmonary outcomes in patients with CF.

Increased physical activity post-exacerbation is associated with decreased systemic inflammation in cystic fibrosis – An observational study

2019 ◽  
Vol 36 (12) ◽  
pp. 1457-1465
Author(s):  
Kate Burton ◽  
Norman R. Morris ◽  
David Reid ◽  
Daniel Smith ◽  
Suzanne Kuys
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Observational Study ◽  
Systemic Inflammation
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