scholarly journals Focal123I-FP-CIT SPECT Abnormality in Midbrain Vascular Parkinsonism

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Paolo Solla ◽  
Antonino Cannas ◽  
Roberta Arca ◽  
Davide Fonti ◽  
Gianni Orofino ◽  
...  
Keyword(s):  
Dopamine Transporter ◽  
Functional Imaging ◽  
Movement Disorders ◽  
Cerebrovascular Diseases ◽  
Vascular Parkinsonism ◽  
Imaging Studies ◽  
Pharmacological Management ◽  
Ipsilateral Striatum ◽  
Midbrain Infarct

Cerebrovascular diseases are considered among possible causes of acute/subacute parkinsonism, representing up to 22% of secondary movement disorders. In cases of suspected vascular parkinsonism (VP), dopamine transporter SPECT has been highly recommended to exclude nigrostriatal dopaminergic degeneration. We report the case of a hemiparkinsonism related to a left midbrain infarct with focal lateralized putaminal abnormalities at123I-FP-CIT SPECT imaging. The asymmetric uptake at dopamine transporter SPECT was different to findings commonly observed in typical PD pattern, because the ipsilateral striatum, in opposite to idiopathic PD, showed normal tracer binding. However, this selective parkinsonism after infarction of the midbrain was responsive to levodopa. In conclusion, we retain that there is a need of more functional imaging studies in VP addressed to a more consistent classification of its different clinical forms and to a better understanding of the adequate pharmacological management.

scholarly journals PET Functional Imaging of Deep Brain Stimulation in Movement Disorders and Psychiatry

2009 ◽  
Vol 29 (11) ◽  
pp. 1743-1754 ◽  
Author(s):  
Benedicte Ballanger ◽  
Marjan Jahanshahi ◽  
Emmanuel Broussolle ◽  
Stéphane Thobois
Keyword(s):  
Deep Brain Stimulation ◽  
Functional Imaging ◽  
Brain Stimulation ◽  
Movement Disorders ◽  
Major Advance ◽  
Imaging Studies ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Neuropsychiatric Diseases ◽  
Deep Brain

Deep brain stimulation (DBS) represents a major advance in the treatment of various severe movement disorders or neuropsychiatric diseases. Our understanding of the mechanism of action of this surgical treatment has greatly benefited from functional imaging studies. Most of these studies have been conducted in patients with Parkinson's disease (PD) treated by bilateral subthalamic nucleus (STN) stimulation. These studies have notably underlined the fact that STN stimulation influences motor, limbic, or associative cortical-subcortical loops in various (sometimes contradictory) ways. We present an up-to-date review of the information provided by functional imaging studies in surgery for PD, dystonia, tremor, as well as in psychiatric disorders such as depression or obsessive-compulsive disorder. On the basis of this information, proposed mechanisms of action of DBS are discussed, as well as the need for additional approaches such as improved anatomical localization of the contact used for stimulation or a better understanding of the electrical distribution around the electrode.

scholarly journals Cerebrovascular diseases in two patients with entire NSD1 deletion

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Toshiyuki Itai ◽  
Satoko Miyatake ◽  
Taku Hatano ◽  
Nobutaka Hattori ◽  
Atsuko Ohno ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Brain Imaging ◽  
Developmental Delay ◽  
Movement Disorders ◽  
Subdural Hematoma ◽  
Early Onset ◽  
Cerebrovascular Diseases ◽  
Brain Contusion ◽  
Abnormal Gait

AbstractWe describe two patients with NSD1 deletion, who presented with early-onset, or recurrent cerebrovascular diseases (CVDs). A 39-year-old female showed developmental delay and abnormal gait in infancy, and developed slowly-progressive intellectual disability and movement disorders. Brain imaging suggested recurrent parenchymal hemorrhages. A 6-year-old male had tremor as a neonate and brain imaging revealed subdural hematoma and brain contusion. This report suggests possible involvement of CVDs associated with NSD1 deletion.

Basic operations in working memory: Contributions from functional imaging studies

2010 ◽  
Vol 214 (2) ◽  
pp. 172-179 ◽  
Author(s):  
Christoph Bledowski ◽  
Jochen Kaiser ◽  
Benjamin Rahm
Keyword(s):  
Working Memory ◽  
Functional Imaging ◽  
Imaging Studies

Hypertensive disorders

ESC CardioMed ◽  
2018 ◽  
pp. 2872-2874
Author(s):  
Renata Cifkova
Keyword(s):  
Blood Pressure ◽  
Laboratory Tests ◽  
Medical Complications ◽  
Pharmacological Management ◽  
Hypertension In Pregnancy ◽  
Hypertensive Disorders ◽  
Hypertensive Disorders In Pregnancy ◽  
Diagnosis Of Hypertension ◽  
In Pregnancy

Hypertensive disorders in pregnancy are the most common medical complications affecting 5–10% of pregnancies worldwide. This chapter discusses the following topics: diagnosis of hypertension, definition and classification of hypertension in pregnancy, additional laboratory tests, management of hypertension in pregnancy, pharmacological management of hypertension in pregnancy, delivery induction, blood pressure postpartum and lactation, and prognosis after pregnancy.

scholarly journals Disentangle the neural correlates of attachment style in healthy individuals

2019 ◽  
Vol 28 (04) ◽  
pp. 371-375 ◽  
Author(s):  
Cinzia Perlini ◽  
Marcella Bellani ◽  
Maria Gloria Rossetti ◽  
Niccolò Zovetti ◽  
Giulia Rossin ◽  
...  
Keyword(s):  
Personality Traits ◽  
Attachment Style ◽  
Functional Imaging ◽  
Psychosocial Functioning ◽  
Attachment Styles ◽  
Neural Correlates ◽  
Current Evidence ◽  
Healthy Individuals ◽  
Imaging Studies ◽  
Wide Range

AbstractSince its development and theorisation in the 60s, attachment theory has greatly influenced both clinical and developmental psychology suggesting the existence of complex dynamics based on the relationship between an infant and its caregiver, that affects personality traits and interpersonal relationships in adulthood. Many studies have been conducted to explore the association between attachment styles and psychosocial functioning and mental health. By contrast, only a few studies have investigated the neurobiological underpinnings of attachment style, showing mixed results. Therefore, in this review, we described current evidence from structural and functional imaging studies with the final aim to disentangle the neural correlates of attachment style in healthy individuals. Overall, different attachment styles have been correlated with volumetric alterations mainly in the cingulate cortex, amygdala, hippocampus and anterior temporal pole. Consistently, functional imaging studies suggested patterns of activations in fronto-striatal-limbic circuits during the processing of social and attachment-related stimuli. Further studies are needed to clarify the neurobiological signature of attachment style, possibly taking into consideration a wide range of demographic, psychosocial and clinical factors that may mediate the associations between the style of attachment and brain systems (e.g., gender, personality traits, psychosocial functioning, early-life experience).

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