scholarly journals Acceptability and Feasibility of Sexually Transmitted Infection Testing and Treatment among Pregnant Women in Gaborone, Botswana, 2015

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Adriane Wynn ◽  
Doreen Ramogola-Masire ◽  
Ponatshego Gaolebale ◽  
Neo Moshashane ◽  
Ogechukwu Agatha Offorjebe ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Trichomonas Vaginalis ◽  
Antenatal Clinic ◽  
Test Results ◽  
Transmitted Infection ◽  
Routine Testing ◽  
Infant Outcomes ◽  
Sexually Transmitted ◽  
Sti Testing ◽  
Maternal And Infant Outcomes

Introduction.Chlamydia trachomatis(CT),Neisseria gonorrhoeae(NG), andTrichomonas vaginalis(TV) are curable sexually transmitted infections (STIs) that can cause adverse maternal and birth outcomes. Most countries do not conduct routine testing during antenatal care. We present data on the acceptability and feasibility of testing and treating pregnant women for STIs in an antenatal clinic in Gaborone, Botswana.Materials and Methods. We offered CT, NG, and TV testing using self-collected vaginal swabs to eligible pregnant women. Participants received same-day test results. Those who tested positive were given treatment.Results. Among the 225 women who were eligible and recruited, 200 (89%) agreed to participate. The median age of our study sample was 30 years; most were unmarried (77%), with a median gestational age of 27 weeks and a 23% HIV prevalence. All participants received their results with at least 72% (n=143) on the same day. Thirty participants (15%) tested positive for an STI, all were treated, and 24 (80%) were treated on the same day.Conclusion. The acceptability of STI testing was high, and the intervention was feasible. This study provides support for continued research into STI prevalence, cost-effectiveness, and the association of STIs with adverse maternal and infant outcomes.

Acceptability and feasibility of screening pregnant women for sexually transmitted infections in Rawalpindi, Pakistan

2021 ◽  
pp. 095646242110076
Author(s):  
Ameen E Chaudry ◽  
Rizwana Chaudhri ◽  
Aasia Kayani ◽  
Lamar W Hayes ◽  
Claire C Bristow ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Sexually Transmitted Infections ◽  
Sexually Transmitted Infection ◽  
Trichomonas Vaginalis ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Sti Testing ◽  
Sexual Histories

Objectives: To understand the acceptability and feasibility of sexually transmitted infection (STI) testing during antenatal care, along with the prevalence of STIs, in Rawalpindi, Pakistan. Methods: We enrolled pregnant women seeking antenatal care and performed STI testing using Cepheid GeneXpert® CT/NG and TV kits and Alere Determine™ HIV and syphilis tests. We used interviewer-administered surveys to collect medical, social, and sexual histories. Participants testing positive for STIs and their partners were treated. Results: We enrolled 1001 women from September to December 2019. Nearly all women offered to participate in this study enrolled. Most women understood the effects an STI can have on their pregnancy (99.6%) and valued STI screening during pregnancy (98.1%). 11 women tested positive for any STI: ( Chlamydia trachomatis = 4, Neisseria gonorrhoeae = 1, and Trichomonas vaginalis = 6). Of those, six presented for a test-of-cure, and two were positive for Trichomonas vaginalis. None tested positive for HIV infection or syphilis ( n = 503). Conclusions: STI testing during antenatal care in Rawalpindi was acceptable, valued, understood, and feasible. The prevalence of STIs in pregnant women was low. Continued prevalence monitoring is warranted.

Prevalence of Trichomonas Vaginalis and its Correlation with Socio-demographic Variables in Pregnant Women in Al-Diwaniya,Iraq

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Shiren Ali Al Hamzawi
Keyword(s):  
Pregnant Women ◽  
Rural Areas ◽  
Trichomonas Vaginalis ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Vaginal Swabs ◽  
Low Education

Estimates of Trichomonas vaginalis prevalence in pregnant women are variable with few studies in Iraq.T. vaginalis is a worldwide prevalent sexually transmitted infection,but fortunately,it is very treatable. Researchers believed that pregnancy is one of the effective factors for T. vaginalis infection in women.A cross-sectional study performed in Obstetrics and Gynecology Department at Maternity and Children Teaching Hospital in Al-Diwaniya city on two hundred female pregnant patients between the ages of 16-45 years. These females had no intercourse for 2–3 days,not using drugs (antibiotics,antiprotozoal or steroids) for the last 15 days. Vaginal discharges of any type with or without itching,burning sensation or both were their main complaints. Vaginal swabs were taken from all participating patients for direct wet mount microscopy and culture for the detection of Trichomonas vaginalis infection. The study showed that twelve out of two hundred examined pregnant women (6%) presented with T. vaginalis infection. The infection was more in those with mothers’ age (26-35) years,housewives,low education,higher parity,and of rural residents. Other maternal variables were not significantly associated with T. vaginalis infection. The study showed a prevalence of (6%) of T. vaginalis infection in pregnant female attendees. Infection was more in those with mothers ’age (26-35) years,housewives,low educational level,higher parity,and living in rural areas.

Prevalence and risk factors for Trichomonas vaginalis infection in pregnant women in South Africa

2020 ◽  
Vol 31 (4) ◽  
pp. 351-358 ◽  
Author(s):  
Nonkululeko Mabaso ◽  
Camille Naicker ◽  
Makandwe Nyirenda ◽  
Nathlee Abbai
Keyword(s):  
Risk Factors ◽  
South Africa ◽  
Pregnant Women ◽  
Trichomonas Vaginalis ◽  
Laboratory Diagnosis ◽  
Antenatal Clinic ◽  
Cross Sectional Study ◽  
Vaginal Swab ◽  
Transmitted Infection ◽  
Cross Sectional

There are insufficient data on the prevalence of Trichomonas vaginalis infection in pregnant women in South Africa. The present study aims to determine the prevalence of T. vaginalis (TV) in pregnant women and identify the risk factors associated with this infection in pregnancy. This was a cross-sectional study which included 362 pregnant women attending the antenatal clinic at the King Edward VIII Hospital in Durban, South Africa. A self-collected vaginal swab was provided by the enrolled women for laboratory diagnosis by real-time polymerase chain reaction. The protozoan load was determined as the logarithm of gene copies per milliliter. The prevalence of TV infection was 12.9% and 59.6% of the women who tested positive were asymptomatic ( p =  0.011). Women who presented with abnormal vaginal discharge had a 4.6 times likelihood of testing positive for TV infection (odds ratio 4.62; 95% confidence interval 1.83 to 11.70; p =  0.001). TV infection was high amongst pregnant women. Therefore, routine testing for this sexually transmitted infection is encouraged for proper management.

scholarly journals Uncovering a Role for Electronic Personal Health Records in Reducing Disparities in Sexually Transmitted Infection Rates Among Students at a Predominantly African American University: Mixed-Methods Study (Preprint)

2017 ◽  
Author(s):  
Kevon-Mark Jackman ◽  
Stefan David Baral ◽  
Lisa Hightow-Weidman ◽  
Tonia Poteat
Keyword(s):  
Health Communication ◽  
Online Survey ◽  
Black Youth ◽  
Personal Health ◽  
Test Results ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Sti Testing ◽  
Signed Rank ◽  
Electronic Personal Health Records

BACKGROUND Black youth continue to bear an overwhelming proportion of the United States sexually transmitted infection (STI) burden, including HIV. Several studies on web-based and mobile health (mHealth) STI interventions have focused on characterizing strategies to improve HIV-related prevention and treatment interventions, risk communication, and stigma among men who have sex with men (MSM), people who use substances, and adolescent populations. The Electronic Sexual Health Information Notification and Education (eSHINE) Study was an exploratory mixed-methods study among students at a historically black university exploring perceptions on facilitating STI testing conversations with partners using electronic personal health records (PHRs). OBJECTIVE The purpose of this paper is to use eSHINE Study results to describe perceived impacts of electronic PHRs on facilitating STI testing discussions between sexual partners. METHODS Semistructured focus groups and individual in-depth interviews were conducted on a heterogeneous sample of students (n=35) between May and July 2014. Qualitative phase findings guided development of an online survey instrument for quantitative phase data collection. Online surveys were conducted using a convenience sample of students (n=354) between January and May 2015. Online survey items collected demographic information, sexual behaviors, beliefs and practices surrounding STI testing communication between partners, and beliefs about the impact of electronic PHR access on facilitating these discussions with partners. Chi-square analysis was performed to assess gender differences across quantitative measures. A Wilcoxon signed rank sum test was used to test the null hypothesis that electronic PHRs are believed to have no effect on the timing of dyadic STI health communication. RESULTS Participants described multiple individual and dyadic-level factors that inhibit initiating discussions about STI testing and test results with partners. Electronic PHRs were believed to improve ability to initiate conversations and confidence in STI screening information shared by partners. Among online survey participants, men were more likely to believe electronic PHRs make it easier to facilitate STI talks with potential partners (59.9% vs 51.9%; χ2=3.93, P=.05). The Wilcoxon signed-rank test results indicate significant increases in perceived discussion timing before sex with electronic PHR access (61.0% vs 40.4%; P<.001). CONCLUSIONS Findings suggest that electronic PHR access in STI screening settings among similar populations of Black youth may improve both motivation and personal agency for initiating dyadic STI health communication. Results from this study will likely inform novel interventions that use access to electronic PHRs to stimulate important health-related discussions between sexual partners. Moving forward requires studying strategies for implementing interventions that leverage electronic PHRs to create new sexual health communication channels with providers, peers, and family among black youth.

scholarly journals Prevalence and treatment outcomes of routine Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana

2017 ◽  
Vol 94 (3) ◽  
pp. 230-235 ◽  
Author(s):  
Adriane Wynn ◽  
Doreen Ramogola-Masire ◽  
Ponatshego Gaolebale ◽  
Neo Moshashane ◽  
Ontiretse Sickboy ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Trichomonas Vaginalis ◽  
Perinatal Outcomes ◽  
Antenatal Clinic ◽  
Sti Testing ◽  
Highly Sensitive ◽  
A Prospective Study

ObjectivesChlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) are curable, mostly asymptomatic, STIs that cause adverse maternal and perinatal outcomes. Most countries do not test for those infections during antenatal care. We implemented a CT, NG and TV testing and treatment programme in an antenatal clinic in Gaborone, Botswana.MethodsWe conducted a prospective study in the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana. We offered pregnant women who were 18 years or older and less than 35 weeks of gestation, CT, NG and TV testing using self-collected vaginal swabs. Testing was conducted using a GeneXpert® CT/NG and TV system. Those who tested positive were given directly observed antibiotic therapy and asked to return for a test of cure. We determined the prevalence of infections, uptake of treatment and proportion cured. The relationships between positive STI test and participant characteristics were assessed.ResultsWe enrolled 400 pregnant women. Fifty-four (13.5%) tested positive for CT, NG and/or TV: 31 (8%) for CT, 5 (1.3%) for NG and 21 (5%) for TV. Among those who tested positive, 74% (40) received same-day, in person results and treatment. Among those who received delayed results (6), 67% (4) were treated. Statistical comparisons showed that being unmarried and HIV infected were positively association CT, NG and/or TV infection. Self-reported STI symptoms were not associated with CT, NG and/or TV infection.ConclusionThe prevalence of CT, NG and/or TV was high, particularly among women with HIV infection. Among women with CT, NG and/or TV infection, those who received same-day results were more likely to be treated than those who received delayed results. More research is needed on the costs and benefits of integrating highly sensitive and specific STI testing into antenatal care in Southern Africa.

scholarly journals Serological Specificity in the Detection of Syphilis among Pregnant Women Attending Antenatal in Some Hospitals in Mubi Metropolis, Adamawa State, Nigeria

2021 ◽  
Vol 8 (5) ◽  
Author(s):  
Richard Elisha ◽  
Abubakar, I.
Keyword(s):  
Pregnant Women ◽  
Serological Test ◽  
Research Work ◽  
Treponema Pallidum ◽  
Vaginal Swab ◽  
Test Results ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
North And South ◽  
Serological Specificity

Syphilis is a sexually transmitted infection (STI) caused by the Treponema pallidum (spirochetes). Syphilis remains a major cause of reproductive morbidity and poor pregnant outcomes in developing countries. This Research work seeks to determine the specificity of serological VDRL test for syphilis against the use of High Vaginal Swab in molecular detection of syphilis among pregnant women attending antenatal in some selected hospitals and clinics in Mubi North and South L.G.A. Adamawa State, Nigeria to subvert the challenges, hence finding lasting solution to the Reproductive and mental health challenges posed by secondary Syphillis. A total of 120 blood samples were collected from 120 consented pregnant women in batches from General hospital, Mubi, Sabon layi clinic, Lokuwa PHC, Lamurde maternity, Kwaja PHC and Alheri Nursing hospital all in Mubi North and South Local Government, during their Antenatal days. In all, 30(25.0 %) of the samples were seropositive, with the highest prevalence recorded as 11(9.17 %) of the 20 samples collected from Kwajah PHC in Mubi South L.G.A. The HVS of pregnant with positive serological test results were subjected to molecular nPCR test to amplify the tpp47 gene of Treponema pallidum. The only amplified fragment which arouse from the positive as the only positive amplification products was analyzed for specificity in an agarose gel developed 0.01 % ethidum bromide for ease of visualization of the band of fragment weight 260 bp tpp47 gene of Treponema pallidum under U.V since all HVS samples showed no bands of amplification, no further sequencing was technically necessary.

scholarly journals Partner notification and treatment for sexually transmitted infections among pregnant women in Gaborone, Botswana

2017 ◽  
Vol 28 (12) ◽  
pp. 1184-1189 ◽  
Author(s):  
Ogechukwu A Offorjebe ◽  
Adriane Wynn ◽  
Neo Moshashane ◽  
Dvora Joseph Davey ◽  
Kaitlin Arena ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Sexually Transmitted Infections ◽  
Trichomonas Vaginalis ◽  
Partner Notification ◽  
Antenatal Clinic ◽  
Sample Collection ◽  
Sexually Transmitted ◽  
Screening Study ◽  
Almost All ◽  
And Control

Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) are sexually transmitted infections (STIs) associated with adverse birth outcomes. Untreated partners contribute to high rates of STI reinfection; thus, partner notification and treatment remain important components of STI care and control. A prospective cohort study was conducted among 300 pregnant women presenting to the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana who enrolled in an STI screening study. Following informed consent and sample collection for CT/NG/TV testing, participants were asked if they were willing to disclose their STI result and to deliver medications to their partner(s). Those who tested positive were asked at a follow-up appointment if they notified their partners. Among the 300 participants, 294 (98%) said they would be willing to tell their partner(s) about their test results if they tested positive, and 284 (95%) said they would be willing to give their partner(s) medication if the option was available. Of those who tested positive and returned for a test of cure, 27 of 32 (84%) reported that they told their partner about the results, and 20 of 32 (63%) reported that their partner received treatment. Almost all pregnant women reported willingness to tell their partner the STI test result and give their partner medications. At test of cure, most women reported informing their partner, although actual treatment receipt was lower. Our findings suggest that pregnant women are willing to utilize patient-based partner notification, but actual partner treatment might be lower than intended.

scholarly journals High prevalence of asymptomatic sexually transmitted infections among human immunodeficiency virus-infected pregnant women in a low-income South African community

2017 ◽  
Vol 29 (4) ◽  
pp. 324-333 ◽  
Author(s):  
Maanda Mudau ◽  
Remco P Peters ◽  
Lindsey De Vos ◽  
Dawie H Olivier ◽  
Dvora J Davey ◽  
...  
Keyword(s):  
Pregnant Women ◽  
South African ◽  
Low Income ◽  
Trichomonas Vaginalis ◽  
Multiple Infections ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Healthcare Facilities ◽  
Sexually Transmitted ◽  
Sectional Analysis

There is a lack of evidence on the burden of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) among HIV-infected pregnant women in South Africa. We conducted a cross-sectional analysis of HIV-infected pregnant women in two healthcare facilities in a South African township to determine the prevalence of CT, NG and TV. HIV-infected pregnant women were recruited during the first antenatal care visit for their current pregnancy and requested to self-collect vulvovaginal swab specimens. Specimens were tested for CT, NG and TV using the Xpert® assay (Cepheid, Sunnyvale, CA). Of 247 tested for CT, NG and TV, 47.8% tested positive for at least one organism; CT = 36.8%, TV = 23.9%, NG = 6.9%. Forty three (17.4%) had multiple infections, of which 42 included CT as one of the infecting organisms. Of the 118 participants who tested positive for at least one sexually transmitted infection (STI), 23.7% reported STI-like symptoms. Among women who tested positive for CT, 29.7% reported symptoms while 47.1 and 27.1% of those who tested positive for NG and TV, respectively, reported symptoms. The high STI prevalence coupled with the low symptom prevalence among infected individuals justifies the use of diagnostic screening approaches rather than syndromic management of STIs in this setting.

scholarly journals Improved molecular laboratory productivity by consolidation of testing on the new random-access analyzer Alinity m

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Martin Obermeier ◽  
Monia Pacenti ◽  
Robert Ehret ◽  
Francesco Onelia ◽  
Rory Gunson ◽  
...  
Keyword(s):  
Trichomonas Vaginalis ◽  
Random Access ◽  
Mycoplasma Genitalium ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
B Virus ◽  
Immunodeficiency Virus ◽  
International Multicenter Study ◽  
Laboratory Productivity ◽  
Laboratory Workflow

AbstractObjectivesAutomated molecular analyzers have accelerated diagnosis, allowing earlier intervention and better patient follow-up. A recently developed completely automated molecular analyzer, Alinity™ m (Abbott), offers consolidated, continuous, and random-access testing that may improve molecular laboratory workflow.MethodsAn international, multicenter study compared laboratory workflow metrics across various routine analyzers and Alinity m utilizing assays for human immunodeficiency virus type 1 (HIV-1), hepatitis C virus (HCV), hepatitis B virus (HBV), high-risk human papillomavirus (HR HPV), and sexually transmitted infection (STI) (Chlamydia trachomatis [CT]/Neisseria gonorrhoeae [NG]/Trichomonas vaginalis [TV]/Mycoplasma genitalium [MG]). Three turnaround times (TATs) were assessed: total TAT (sample arrival to result), sample onboard TAT (sample loading and test starting to result), and processing TAT (sample aspiration to result).ResultsTotal TAT was reduced from days with routine analyzers to hours with Alinity m, independent of requested assays. Sample onboard TATs for standard workflow using routine analyzers ranged from 7 to 32.5 h compared to 2.75–6 h for Alinity m. The mean sample onboard TAT for STAT samples on Alinity m was 2.36 h (±0.19 h). Processing TATs for Alinity m were independent of the combination of assays, with 100% of results reported within 117 min.ConclusionsThe consolidated, continuous, random-access workflow of Alinity m reduces TATs across various assays and is expected to improve both laboratory operational efficiency and patient care.

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