scholarly journals New Collagen-Dextran-Zinc Oxide Composites for Wound Dressing

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Georgeta Păunica-Panea ◽  
Anton Ficai ◽  
Minodora Maria Marin ◽  
Ștefania Marin ◽  
Mădălina Georgiana Albu ◽  
...  

The goal of this paper was the design, development, and characterization of some new composites, based on collagen and dextran as natural polymers and zinc oxide as antimicrobial, to be used in wound healing. Collagen hydrogels with various concentrations of dextran and zinc oxide were investigated in terms of rheological analysis. The spongious composites, obtained by freeze-drying of hydrogels, were evaluated by morphology (SEM), water uptake, and biological (enzymatic biodegradation) analysis. All the results were strongly influenced by the nature and concentration of composite components. Based on the performances of the hydrogels, stationary rheometry, porous structure, morphology, and biological behavior, the antimicrobial spongious composite based on collagen and dextran with 50% ZnO were the most promising for future applications in wound dressing and a biomaterial with high potential in skin regeneration.

2021 ◽  
Vol 877 ◽  
pp. 21-26
Author(s):  
Shuai Yuan ◽  
Lin Yuan ◽  
Chen Gao ◽  
Xue Fei Hu ◽  
Chin San Wu ◽  
...  

Biodegradable composite from polycaprolactone (PCL) and Graphene/zinc oxide (Graphene/ZnO) is studied. The Graphene/ZnO content is at 0.5%, 1.5% in PCL. Neat PCL and composites were characterized by microstructure, mechanical properties and thermal properties. Scanning electron micrographs show that the additive has agglomerated in PCL/Graphene/ZnO. Agglomeration of the filler results in reduced tensile properties of the composite. The result from XRD indicates Graphene/ZnO can improve the crystallinity of PCL. According to the results of buried soil test and analysis, Graphene/ZnO can reduce the biodegradation rate of PCL and make the material more durable. This new biodegradable composite material can be used as a new environmentally friendly material.


2018 ◽  
Vol 915 ◽  
pp. 98-103 ◽  
Author(s):  
Duygu Candemir ◽  
Filiz Boran

In this study, copper oxide (CuO) nanostructures were successfully prepared by adding EG (ethylene glycol) and PEG (4000, 8000) (polyethylene glycol) via an in-situ chemical precipitation method. EG and PEG (4000, 8000) were effective for changing the particular size of CuO and we examined the effects of drying type such as freeze drying, muffle and horizontal furnace on the size of CuO nanostructure. The structure, morphology and elemental analysis of CuO nanostructure were analyzed by field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDS). Also, the CuO nanostructures showed excellent electrical conductivity by the changing of PEG’s molecular weight and drying processes.


2021 ◽  
Vol 11 (23) ◽  
pp. 11573
Author(s):  
Jeongyeon Choi ◽  
Heekyung Jeon

This study focused on the manufacturing of functional superabsorbent sponges using natural polymers. An alginate/CMC-embedded dextran hybrid dual-layer formulation was prepared using the freeze-drying method. The physical properties of the formulation were characterized using a field emission scanning electron microscope and a universal testing machine, and the swelling ratio was calculated. Cell viability assays were performed using keratinocytes (HaCaT cells). The results showed that this formulation can absorb a large amount of moisture and provide morphological stability through its tensile strength and uniform porosity, and this was verified by its biocompatibility. We believe that in the future, by combining this novel hybrid dual-layer superabsorbent sponge with antibacterial agents with excellent porosity, it would serve as a medical material for producing bandages that can absorb blood and body fluids, feminine hygiene products, and functional antibacterial masks.


2014 ◽  
Vol 1626 ◽  
Author(s):  
Changfeng Chen ◽  
Li Liu ◽  
Qiong Wang ◽  
Tao Huang ◽  
Yue`e Fang

ABSTRACTThe present investigation involves the synthesis of chitosan based composite sponges in view of their applications in wound dressing, antibacterial and haemostatic. A facile CO2 bubbles template freeze-drying method was developed for the fabrication of macroporous chitosan- poly(vinyl alcohol) (PVA) composite sponges with a typical porosity of 50% and pore size of 100-300 µm. The composite sponges show a high water absorption rate up to 60 times of its weight and a water vapor transmission rate of 30 ∼ 70g/m2 • h. Effects of the content of cross-linking agent and PVA on mechanical properties and moisture permeability were examined. Improved strength and flexibility of the chitosan sponges were observed with the presence of PVA. Further, the antibacterial and haemostatic activities have been demonstrated. The Chitosan/PVA sponges of high liquid absorption, appropriate moisture permeability, excellent antimicrobial and haemostatic activities have a great potential for wound dressing applications.


2013 ◽  
Vol 771 ◽  
pp. 141-146 ◽  
Author(s):  
Ping Zhang ◽  
Shan Shan Wu

This paper reports a surface functional polymer- poly(N-isopropylacrylamide) (PNIPAM) was grafted on the surface of zinc oxide (ZnO) nanoparticles. It has been demonstrated that Reversible addition fragmentation chain-transfer (RAFT) agent was successfully grafted onto the surface of ZnO. PNIPAM chains were successfully grafted from the surface of ZnO via RAFT process by using RAFT agent immobilized on ZnO. The effect of surface modification on the size, structure, morphology, and properties of ZnO nanoparticles was investigated. The thickness of a PNIPAM monolayer bound to the ZnO core is somewhat larger than the size of the random coil of the corresponding free PNIPAM in aqueous solution, which suggests that the conformation of a PNIPAM chain bound to the ZnO core is extended.


1991 ◽  
Vol 6 (11) ◽  
pp. 2452-2456 ◽  
Author(s):  
A. Padilla ◽  
A. Vázquez ◽  
V.M. Castaño

Zinc oxide (ZnO) powders were mixed with Polyacrylic Acid (PAA) to form waterless cements. The optimal ZnO/PAA ratio in terms of mechanical strength was found. Also, the role of the relation ZnO to PAA, the curing time, and the strain rate on the final properties of the composites was studied.


2014 ◽  
Vol 1 (4) ◽  
pp. 16-19
Author(s):  
Vivek Talwar ◽  
◽  
Ravi Chand Singh ◽  

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