Effects ofStreptococcus sanguinisBacteriocin on Deformation, Adhesion Ability, and Young’s Modulus ofCandida albicans
In order to study the thallus changes on microscopic morphology and mechanical properties ofCandida albicansantagonized byStreptococcus sanguinisbacteriocin, the adhesion ability and Young’s modulus of thalli and hypha ofCandida albicanswere measured by the relative measurement method using atomic force microscope’s (AFM) tapping model. The results showed that the average adhesion ability and Young’s modulus of thalli were7.35±0.77 nN and7.33±1.29 Mpa, respectively; the average adhesion ability and Young’s modulus of hypha were9.82±0.39 nN and4.04±0.76 Mpa, respectively. After being antagonized byStreptococcus sanguinisbacteriocin, the adhesion ability was decreased along with the increasing of deformation in reaction region and Young’s modulus followed the same changes. It could be concluded that the adhesion ability of hypha was greater than thalli, Young’s modulus of hypha was less than thalli, and adhesion ability and Young’s modulus ofCandida albicanswere decreased significantly after being antagonized byStreptococcus sanguinisbacteriocin.