scholarly journals 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ioana Golu ◽  
Ioan Sporea ◽  
Lavinia Moleriu ◽  
Anca Tudor ◽  
Marioara Cornianu ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Shear Wave ◽  
Thyroid Tissue ◽  
Shear Wave Elastography ◽  
Study Groups ◽  
Tertiary Hyperparathyroidism ◽  
A Value ◽  
Parathyroid Lesions ◽  
The Mean ◽  
Thyroid Parenchyma

Background and Aims. 2D-shear wave elastography (2D-SWE) is a relatively new elastographic technique. The aim of the present study is to determine the values of the elasticity indexes (EI) measured by 2D-SWE in parathyroid benign lesions (adenomas or hyperplasia) and to establish if this investigation is helpful for the preoperative identification of the parathyroid adenoma. Material and Methods. The study groups were represented by 22 patients with primary or tertiary hyperparathyroidism, diagnosed by specific tests, and 43 healthy controls, in whom the thyroid parenchyma was evaluated, in order to compare the EI of the thyroid tissue with those of the parathyroid lesions. Results. The mean EI measured by 2D-SWE in the parathyroid lesions was 10.2 ± 4.9 kPa, significantly lower than that of the normal thyroid parenchyma (19.5 ± 7.6 kPa; p=0.007), indicating soft tissue. For a cutoff value of 12.5 kPa, the EI assessed by 2D-SWE had a sensitivity of 93% and a specificity of 86% (AUC = 0.949; p<0.001) for predicting parathyroid lesions. Conclusion. A value lower than 12.5 kPa for the mean EI measured by 2D-SWE can be used to confirm that the lesion/nodule is a parathyroid adenoma.

scholarly journals Shear Wave Elastography versus Strain Elastography in Diagnosing Parathyroid Adenomas

2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Laura Cotoi ◽  
Daniela Amzar ◽  
Ioan Sporea ◽  
Andreea Borlea ◽  
Dan Navolan ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Shear Wave ◽  
Muscle Tissue ◽  
Thyroid Tissue ◽  
Shear Wave Elastography ◽  
Strain Ratio ◽  
Strain Elastography ◽  
Parathyroid Adenomas ◽  
The Mean ◽  
Thyroid Parenchyma

Objectives. The aim of the study was to compare elastographic means in parathyroid adenomas, using shear wave elastography and strain elastography. Methods. This prospective study examined 20 consecutive patients diagnosed with primary hyperparathyroidism and parathyroid adenoma, confirmed by biochemical assay, technetium-99 sestamibi scintigraphy, and pathology report, after parathyroid surgery. All patients were examined on conventional 2B ultrasound, 2D shear wave elastography, and strain elastography. We determined using 2D shear wave elastography (SWE) the elasticity index (EI) in parathyroid adenoma, thyroid parenchyma, and surrounding muscle and examined using strain elastography the parathyroid adenoma, and determined the strain ratio with the thyroid tissue and muscle tissue. Results. All patients had positive sestamibi scintigraphy and underwent surgery, with confirmation of parathyroid adenoma in all cases. The mean parathormone (PTH) value before surgery was 153.29 pg/ml (36.5, 464.8) and serum calcium concentration was 10.5 mg/dl (9, 11.5). We compared using 2D-SWE and strain elastography parathyroid adenoma with thyroid tissue and with surrounding muscle. The mean EI measured by SWE in parathyroid adenoma was 4.74 ± 2.74 kPa and in thyroid parenchyma was 11.718 ± 4.206 kPa (mean difference = 6.978 kPa, p<0.001), and the mean EI value in muscle tissue was 16.362 ± 3.829 kPa (mean difference = 11.622, p<0.001). Using ROC analysis, we found that an EI below 7 kPa correctly identifies parathyroid tissue. We evaluated parathyroid adenomas using strain elastography by color mapping and strain ratio as a semiquantitative measurement; however, we could not find any statistical correlation comparing the strain ratio obtained from the parathyroid adenoma with the thyroid tissue (p=0.485). Conclusion. Ultrasound elastography is a helpful tool in identifying parathyroid adenomas. A cutoff value below 7 kPa can be used in 2D-SWE. Color maps in strain elastography without adding strain ratio can be used, parathyroid adenoma being identified as score 1 in the Rago criteria.

scholarly journals The diagnostic value of shear wave elastography for parathyroid lesions and comparison with cervical lymph nodes

2017 ◽  
Vol 19 (4) ◽  
pp. 386 ◽  
Author(s):  
Ahmet Veysel Polat ◽  
Mesut Ozturk ◽  
Behic Akyuz ◽  
Cetin Celenk ◽  
Mehmet Kefeli ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Parathyroid Hyperplasia ◽  
Tissue Imaging ◽  
Roc Curve Analysis ◽  
Cervical Lymph Nodes ◽  
Parathyroid Adenomas ◽  
Parathyroid Lesions ◽  
The Mean

Aims: The aim of this study was to prospectively assess the feasibility of the Virtual Touch tissue imaging quantification (VTIQ) method of shear wave elastography (SWE) for the discrimination of parathyroid lesions and to compare the lesions’ stiffness with that of cervical lymph nodes.Materials and methods: SWE using VTIQ was performed on 66 patients with 87 histopathologically proven parathyroid lesions (54 parathyroid adenomas and 33 parathyroid hyperplasia) and 29 patients with 31 inflammatory cervical lymph nodes. The mean SWVs of the lesions were compared and receiver operating characteristic (ROC) curve analysis was used to evaluate diagnostic performance.Results: The mean SWV of parathyroid adenomas (2.16±0.33 m/s) differed significantly from those of parathyroid hyperplasia and lymph nodes (1.75±0.28 m/s and 1.86±0.37 m/s respectively, p<0.001). Selecting a cutoff value of 1.92 m/s for diagnosing adenoma led to 80% sensitivity and 82% specificity (area under the curve [AUC]: 0.832 [95% confidence interval (CI): 0.742–0.921], p< 0.001).Conclusions: The VTIQ method of SWE can contribute to the differentiation of parathyroid adenoma from parathyroid hyperplasia and cervical lymphnodes.

scholarly journals Shear wave elastography in optic neuritis: diagnostic accuracy of the optic nerve and adjacent fat tissue values

2021 ◽  
Vol 21 (86) ◽  
pp. e194-e199
Author(s):  
Mustafa Devran Aybar ◽  
◽  
Onder Turna ◽  
Keyword(s):  
Optic Nerve ◽  
Diagnostic Accuracy ◽  
Optic Neuritis ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Curve Analysis ◽  
Fat Tissue ◽  
Roc Curve Analysis ◽  
Optic Nerves ◽  
The Mean

Introduction: In this study, we attempt to determine the diagnostic performance of shear wave elastography of the optic nerve and adjacent fat tissue in patients with optic neuritis. Methods: The study included a patient group consisting of 72 eyes of 36 patients who were diagnosed with unilateral optic neuritis, and an age-matched control group of 36 eyes of 18 healthy subjects. The patient group consisted of 25 multiple sclerosis patients and 11 recurrent isolated optic neuritis patients. The mean shear wave elastography values of the optic nerves and intraorbital fat tissue adjacent optic nerves were recorded using m/s and kPa as units. ROC curve analysis was performed, and the diagnostic accuracy of shear wave elastography values was determined. Results: The mean shear wave elastography values of the optic nerves with neuritis (2.49 ± 0.41 m/s and 17.56 ± 4.42 kPa) were significantly higher than the values of the contralateral normal optic nerves (1.71 ± 0.32 m/s and 9.02 ± 2.34 kPa) (p = 0.006 and p = 0.004, respectively) in the optic neuritis group. The mean shear wave elastography values of intraorbital fat tissue adjacent optic nerves with neuritis (1.87 ± 0.32 m/s and 9.65 ± 1.12 kPa) were significantly higher than the values of the contralateral normal side (1.47 ± 0.27 m/s and 6.78 ± 1.14 kPa) (p = 0.025 and p = 0.022, respectively) in the optic neuritis group. ROC curve analysis showed a high diagnostic accuracy for determining optic neuritis with shear wave elastography values of the optic nerves (AUC 0.955 [95% CI, 0.933–0.978] in m/s and AUC 0.967 [95% CI, 0.940–0.985] in kPa). Conclusions: Shear wave elastography may be an important alternative diagnostic tool in the diagnosis of optic neuritis.

scholarly journals Evaluation of Inter-System Variability in Liver Stiffness Measurements

2018 ◽  
Vol 40 (01) ◽  
pp. 64-75 ◽  
Author(s):  
Giovanna Ferraioli ◽  
Annalisa De Silvestri ◽  
Raffaella Lissandrin ◽  
Laura Maiocchi ◽  
Carmine Tinelli ◽  
...  
Keyword(s):  
Shear Wave ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Mean Difference ◽  
Observer Agreement ◽  
Concordance Correlation ◽  
Limits Of Agreement ◽  
Inter Observer Variability ◽  
System Variability ◽  
The Mean

Abstract Aim The primary aim of this study was to determine the inter-system variability of liver stiffness measurements (LSMs) in patients with varying degrees of liver stiffness. The secondary aim was to determine the inter-observer variability of measurements. Materials and Methods 21 individuals affected by chronic hepatitis C and 5 healthy individuals were prospectively enrolled. The assessment of LSMs was performed using six ultrasound (US) systems, four of which with point shear wave elastography (p-SWE) and two with 2 D shear wave elastography (2D-SWE) systems. The Fibroscan (Echosens, France) was used as the reference standard. Four observers performed the measurements in pairs (A-B, C-D). The agreement between different observers or methods was calculated using Lin’s concordance correlation coefficient. The Bland-Altman limits of agreement (LOA) were calculated as well. Results There was agreement above 0.80 for all pairs of systems. The mean difference between the values of the systems with 2D-SWE technique was 1.54 kPa, whereas the maximum mean difference between the values of three out of four systems with the pSWE technique was 0.79 kPa. The intra-patient concordance for all systems was 0.89 (95 % CI: 0.83 – 0.94). Inter-observer agreement was 0.96 (95 % CI: 0.94 – 0.98) for the pair of observers A-B and 0.93 (95 % CI: 0.89 – 0.96) for the pair of observers C-D. Conclusion The results of this study show that the agreement between LSMs performed with different US systems is good to excellent and the overall inter-observer agreement in “ideal conditions” is above 0.90 in expert hands.

Placental elasticity assessment by point shear wave elastography in pregnancies with intrauterine growth restriction

2019 ◽  
Vol 47 (8) ◽  
pp. 841-846 ◽  
Author(s):  
Murat Akbas ◽  
Faik M. Koyuncu ◽  
Burcu Artunç-Ulkumen
Keyword(s):  
Pregnant Women ◽  
Shear Wave ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Shear Wave Elastography ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
The Mean ◽  
Adverse Perinatal Outcomes ◽  
Doppler Indices

Abstract Background Placental elasticity varies in different diseases. Our objective was to evaluate placental elasticity using point shear wave elastography (pSWE) in pregnancies with intrauterine growth restriction (IUGR). Methods A total of 66 pregnant women with IUGR and 81 healthy pregnant women were enrolled. Placental elasticity was measured using the transabdominal pSWE method. Ten measurements were made, and the mean was accepted as the mean placental elasticity value in each case. The results for IUGR pregnancies and controls were compared. Results The mean pSWE values were significantly higher in pregnancies with IUGR, which means that women with IUGR have stiffer placentas (P < 0.001). Furthermore, the pSWE values were significantly and positively correlated with Doppler indices and adverse perinatal outcomes. Conclusion The pregnancies with IUGR had stiffer placentas than the healthy controls. The utilization of pSWE for placental elasticity may be useful in the diagnosis and management of IUGR as a supplement to the existing ultrasonography methods.

scholarly journals Evaluation of Functional Recovery Following Achilles Tendon Ruptures by Shear Wave Elastography: A Before-and-After Study

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Donglin Bian ◽  
Xuemei Wang ◽  
Kun Huang ◽  
Zhen Zhang
Keyword(s):  
Achilles Tendon ◽  
Shear Wave ◽  
Functional Recovery ◽  
Shear Wave Elastography ◽  
Postoperative Recovery ◽  
Postoperative Function ◽  
Time Points ◽  
Before And After ◽  
Tendon Ruptures ◽  
The Mean

Background: Sonoelastography is extensively used for clinical diagnosis. Different types of elastography can be used to assess the elastic properties (stiffness) of tissues. For quantitative analyses, shear wave elastography (SWE) has been applied as a non-invasive method in the past decade. Today, SWE is widely used for diagnosing diseases. However, a limited number of studies have investigated musculoskeletal injuries and neoplastic diseases. Objectives: This study aimed to evaluate the postoperative functional recovery of Achilles tendon ruptures by SWE to determine the Achilles tendon function and provide reliable evidence for clinicians. Methods: SWE was used to measure elasticity in 67 patients with Achilles tendon ruptures. In the postoperative stage, 17 patients were lost to follow-up. The remaining 50 patients with Achilles tendon ruptures were examined. Each patient was followed-up for one, three, and six months postoperatively. The 0° flexion of the ankle joint was considered as the standard position. The mean elasticity (Emean) of the Achilles tendon was measured and recorded at different time points before and after surgery. Besides, the thickness and width of the Achilles tendon were measured at the corresponding time points. Results: The mean elasticity (Emean) of normal and ruptured Achilles tendons was 447.4 ± 59.57 and 63.84 ± 45.18 kPa, respectively in 50 patients with ruptured Achilles tendons before surgery. On the other hand, the Emean values of ruptured Achilles tendons in one-, three-, and six-month follow-ups were 110.3 ± 35.60, 183.4 ± 46.08, and 279.1 ± 48.18 kPa in 50 patients, respectively. Regarding the Emean, the difference between the five time points was significant (F = 418.5, P < 0.01). With prolongation of postoperative recovery, the Emean of the Achilles tendon gradually increased; the Emean value significantly increased at six months after surgery. Conclusions: The quantitative analysis of the postoperative function of Achilles tendon, based on the Emean value obtained by SWE, can be helpful in guiding clinicians to objectively examine the prognosis of patients.

Application of Shear Wave Elastography in the Diagnosis of Thyroid Nodules of Thyroid Imaging Report and Data System

2020 ◽  
Vol 10 (4) ◽  
pp. 864-867
Author(s):  
Jia Zheng ◽  
Xiaoxin Wang ◽  
Xianjing Han ◽  
Chunyan Li ◽  
Jianan Wang ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Shear Wave ◽  
Thyroid Nodules ◽  
Ultrasound Examination ◽  
Young's Modulus ◽  
Shear Wave Elastography ◽  
Diagnostic Value ◽  
Data System ◽  
Thyroid Imaging ◽  
The Mean

The purpose of this study is to explore whether shear wave elastography has diagnostic value in distinguishing benign and malignant thyroid imaging report and data system (TI-RADS) nodules, so as to provide more accurate information for clinical diagnosis and treatment of thyroid nodules. In this study, 134 patients with thyroid nodules who underwent ultrasound examination from February 2018 to October 2018 are collected. Firstly, according to the diagnostic criteria proposed by Horvath, TI-RADS grading is performed on them, and 78 patients with TI-RADS4 single solid nodules are screened out. Secondly, conventional ultrasound examination is performed on all the researchers, and shear wave elastographies are obtained 1 week after the examination. Thirdly, parameters of each lesion are measured by ultrasound physicians, and the maximum, minimum and average values of Young's modulus of each lesion are recorded. The results show that the mean and maximum of Young's modulus of benign lesions are (26.31 ± 9.88) kPa and (51.36 ± 14.51) kPa, respectively, the mean and maximum of Young's modulus of malignant lesions are (48.36 ± 16.53) and (69.15 ± 19.98) kPa, respectively, and the area under the ROC curve of Emean and Emax is 0.852 and 0.748, respectively. Therefore, shear wave elastography is a new type of ultrasound elastography, which has the advantages of objectivity and little influence from operators without artificial pressure. It has high sensitivity, specificity and accuracy in diagnosing benign and malignant thyroid nodules. Among them, the average value of Young's modulus has the greatest diagnostic value.

scholarly journals Potential of Using Shear Wave Elastography in the Clinical Evaluation and Monitoring of Changes in Masseter Muscle Stiffness

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Cyprian Olchowy ◽  
Mieszko Więckiewicz ◽  
Luca Maria Sconfienza ◽  
Mateusz Łasecki ◽  
Piotr Seweryn ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Shear Wave ◽  
Masseter Muscle ◽  
Severe Pain ◽  
Shear Wave Elastography ◽  
Muscle Stiffness ◽  
Sensitive Tool ◽  
Massage Treatment ◽  
The Mean ◽  
Evaluation And Monitoring

The study aimed to evaluate masseter muscle stiffness in adult healthy volunteers referred to a massage treatment and also to investigate whether shear-wave elastography can be used to monitor the effect of massage on the masseter muscle. The study included 21 healthy volunteers, who were subjected to a 30-minute massage of the masseter muscle. Muscle stiffness was measured by shear-wave elastography before and directly after the massage. Pain during the massage was assessed using the visual analogue scale (VAS). The data of 20 patients (one excluded due to severe pain) with a median age of 34.5 years were analysed. The stiffness values were 11.46 ± 1.55 kPa before and 8.97 ± 0.96 kPa after the massage ( p < 0.0001 ). The mean drop was 2.49 ± 1.09 kPa. The greatest decrease was observed in people with higher elasticity values before the massage (r = 0.79; p < 0.0001 ). The median intensity of pain was 7.2 (range: 6–9.5). We concluded that shear-wave elastography is a sensitive tool to monitor changes in the stiffness of the masseter muscle.

scholarly journals Shear wave elastography and parathyroid adenoma: A new tool for diagnosing parathyroid adenomas

2016 ◽  
Vol 85 (9) ◽  
pp. 1586-1593 ◽  
Author(s):  
Ghobad Azizi ◽  
Kelé Piper ◽  
James M Keller ◽  
Michelle L. Mayo ◽  
David Puett ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Parathyroid Adenomas

scholarly journals Shear wave elastography: Can it be a new radiologic approach for the diagnosis of erectile dysfunction?

Ultrasound ◽  
2017 ◽  
Vol 25 (3) ◽  
pp. 150-155 ◽  
Author(s):  
Rustu Turkay ◽  
Ercan Inci ◽  
Mustafa Gurkan Yenice ◽  
Volkan Tugcu
Keyword(s):  
Erectile Dysfunction ◽  
Positive Predictive Value ◽  
Shear Wave ◽  
Predictive Value ◽  
Corpus Cavernosum ◽  
Shear Wave Elastography ◽  
Significant Difference ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Introduction Erectile dysfunction (ED) is a common health problem among males, and radiology has limited use in its diagnosis and treatment. Shear wave elastography (SWE) is a new sonographic technique. In this study, we examined the significance of SWE in the diagnosis of ED. Methods The study included a total number of 70 participants. The mean age of the participants was 54.14 ± 8.03 years (range: 39 and 71 years old). We composed two groups. Group 1 had 35 patients who presented to the urology clinic in our hospital complaining of ED, and had a score of 17 or lower from the International Index of Erectile Function (IIEF) questionnaire. Group 2 consisted of 35 healthy volunteers who did not have ED. SWE measurements were performed from corpus cavernosum penis in both groups, and the results were noted. Differences between the groups were evaluated statistically. Results The difference between the mean SWE measurements of two groups (Group 1: 20.94 ± 6.23 kPa and group 2: 24.63 ± 7.58 kPa) was found to be statistically significant ( p = 0.027; p < 0.05). For a cut-off value of 17.1 kPa, the SWE method has specificity, sensitivity, positive predictive value, and negative predictive value regarding diagnosis of ED as 94.29%, 34.29%, 85.71%, and 58.93%, respectively. The mean age of the groups did not show a statistically significant difference ( p = 0.287; p > 0.05). Conclusions Due to its high specificity and positive predictive value, SWE can offer useful data in the radiologic evaluation of ED cases.

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