scholarly journals Ulcerative Lesions: A Rare Cutaneous Manifestation of Brucellosis

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Abbas Azadi ◽  
Payman Jafarpour Fard ◽  
Mohammad Almasian

Brucellosis is a disease that is transmitted from animals to humans mainly via the consumption of unpasteurized dairy products, and it can involve any organ all over the body. Here, we report a significant rare case of brucellosis with cutaneous manifestations in a 52-year-old male patient whose disease was diagnosed via a serology test. The patient received standard antibiotic treatment, and his cutaneous lesions healed quickly. Although the cutaneous manifestations of brucellosis are exceedingly rare, in case of encountering ulcerative lesions and other cutaneous findings, particularly in endemic areas, infection with brucellosis should be kept in mind as an important differential diagnosis.

2014 ◽  
Vol 6 (3) ◽  
pp. 113-119 ◽  
Author(s):  
Sonya Marina ◽  
Valja Broshtilova ◽  
Ivo Botev ◽  
Dimitrina Guleva ◽  
Maria Hadzhiivancheva ◽  
...  

Abstract Although toxoplasmosis is one of the most widely spread infections in the world, types that involve the skin are extremely rare. However, skin lesions are not specific; moreover, they are quite diverse, which makes the diagnosis of cutaneous toxoplasmosis rather difficult. Thus, differential diagnosis should include a number of other diseases. We present a case of a 43-year-old immunocompetent man with multiple livid erythematous papules and nodules with yellowish discharge that involved the skin of the body and the extremities. By using electro-chemiluminescence immunoassay, immunoglobulin G antibodies to Toxoplasma gondii were detected in the serum, confirming the diagnosis of toxoplasmosis. The treatment with pyrimethamine and trimethoprim-sulfamethoxazole led to complete resolution of skin lesions. In conclusion, although rare in the dermatological practice, cutaneous toxoplasmosis should be considered in all patients presenting with lymphadenopathy, non-specific skin eruptions, especially nodular and colliquative, blood eosinophilia and histological findigs revealing abundant eosinophilic inflitrations.


Rheumatology ◽  
2020 ◽  
Vol 59 (Supplement_2) ◽  
Author(s):  
Subhasish Deb ◽  
Srinivasan Srirangan

Abstract Background Rheumatoid arthritis has multiple cutaneous manifestations with rheumatoid nodule being the commonest one. A maculopapular rash in setting of rheumatoid arthritis has a varied list of differentials including rheumatoid vasculitis, pyoderma gangrenosum, rheumatoid neutrophilic dermatosis, interstitial granulomatous dermatitis and palisaded neutrophilic granulomatous dermatitis. We present a rare case of patient with rheumatoid arthritis with perforating collagenosis. Methods A case report is presented in the results section. Results A 64 year old lady known to have seropositive rheumatoid arthritis for the past 6 years with poor compliance to treatment presented with maculopapular lesions on both her legs and abdomen. The lesions were itchy in nature and later became ulcerative. The lesions spread to various parts of the body over the next 4 weeks and patient was seen by a dermatologist who initially prescribed topical therapy and the patient came off her disease modifying anti rheumatic agents. She underwent a skin biopsy as initial investigations were otherwise unremarkable. Skin biopsy revealed a diagnosis of perforating collagenosis. She was given topical steroids and counselled regarding the need to take her disease modifying anti rheumatic drugs regularly. There was 95% resolution of skin lesions within 6 months. Conclusion Perforating collagenosis is a skin disorder characterised by transepithelial expulsion of dermal tissue which presents as a papulonodular rash with central keratin plugs. It is usually associated with diabetes mellitus and chronic kidney disease but rarely been reported in association with rheumatoid arthritis. Literature review revealed that there have been only 2 cases reported previously. The first case has been described in 2010 in a man from Singapore on treatment for RA for 2 years. Second case has been described by Ikeda et al in 2019 in a case of rheumatoid vasculitis. Clinically it presents as umbilicated, hyperkeratotic papules with a central white keratotic crust. Koebnerization may be seen and itching of surrounding regions may lead to papules to coalesce and form plaques. A biopsy will reveal features similar to those seen in the primary disease where perforating collagenosis shows cup shaped invagination of the epidermis filled with a plug consisting of keratin and cellular debris. There have been no trials and treatment is based on case reports. We believe that better compliance to her disease modifying anti rheumatic agent therapy, leading to improved treatment of the systemic cause had a significant role in resolving her skin lesions. Disclosures S. Deb None. S. Srirangan None.


2017 ◽  
Vol 132 (2) ◽  
pp. 184-187 ◽  
Author(s):  
G B Singh ◽  
S Shukla ◽  
P Kumari ◽  
I Shukla

AbstractBackground:Extra-nasopharyngeal angiofibroma is a rare but distinct clinical entity, different from juvenile angiofibroma.Methods:This clinical record elucidates the only case of extra-nasopharyngeal angiofibroma arising from the septum in a female child, who presented with epistaxis.Results:The histopathological diagnosis was confirmed by immunohistochemistry, and the case was managed surgically with no recurrence.Conclusion:In a female paediatric patient presenting with epistaxis, extra-nasopharyngeal angiofibroma (of the inferior turbinate) is a rare albeit important differential diagnosis, as it challenges the hormonal theory of angiofibroma aetiopathogenesis.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Mohammed Kabir Saleh

Teratomas are considered the most common congenital tumors located on the dorsal midline and arise from cells derived from more than one germ layer (i.e. ectodermic, endodermis and mesodermic) at different regions of the body. Those in the head and neck regions are considered rare with an incidence of 1-3.5% of all cases. Imaging provides critical information that helps in formulating differential diagnosis even though, history and physical examination provides critical information in making the diagnosis. A successfully surgically treated case of an usually huge parietooccipital teratoma in a 40 days old girl was presented with emphasis on the importance of imaging in diagnosis and management.


2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Zara Sheikh ◽  
Sadasivam Selvakumar ◽  
Patrick Goon

Abstract Aneurysmal disease can occur in any vessel in the body and occur most commonly the aorta, cerebral and popliteal arteries; however, aneurysms of the digital artery remain a rare presentation. They form an important differential diagnosis in any patient presenting with a mass in the hand. This report presents the case of a 64-year-old man with a true aneurysm of the common palmar digital artery who underwent successful repair, following excision and end to end anastomosis. Only 21 cases of true digital artery aneurysm have been reported; we review the literature pertaining to the diagnosis and management of digital artery aneurysms since they were first described by Baruch et al in 1977.


1990 ◽  
Vol 104 (3) ◽  
pp. 244-247 ◽  
Author(s):  
J. Hadley ◽  
A. T. Coady ◽  
C. A. Milford

AbstractOrbital pseudotumour is a non-specific inflammation of the orbit which forms a tumour-like mass composed of increased connective tissue and ground substance with vascular proliferation and an infiltrate of chronic inflammatory cells. No demonstrable aetiological agents are found locally, and there is no evidence of specific disease entities such as Hodgkins, SLE or temporal arteritis.The condition may present in many different ways to the otolaryngologist, and is therefore a rare but important differential diagnosis to be born in mind. We report a rare case of orbital pseudotumour presenting initially with involvement of the maxillary antrum and in association with Riedel's thyroiditis.


2020 ◽  
Vol 16 (3) ◽  
pp. 187-192
Author(s):  
Jaehyun Bae ◽  
Dongkeun Jun ◽  
Jeenam Kim ◽  
Hyungon Choi ◽  
Donghyeok Shin ◽  
...  

Dermatomyositis (DM) is an autoimmune inflammatory myopathy with some cutaneous manifestations. We present the case of a patient with a bone-depth skin ulceration on the elbow that was well healed with a transposition flap using a dorsal interosseous artery perforator. A 56-year-old man reported difficulties when climbing stairs and diffuse pain of unclear origin throughout his body that started 2 months previously. The patient was diagnosed with DM, and the department of plastic and reconstructive surgery was consulted for the management of an ulcerative skin lesion on the left elbow. The dorsal interosseous artery was first detected by vascular Doppler ultrasonography, and a transposition flap was designed including the pedicle. The flap was transposed to cover the bone exposure over the olecranon. At 4 weeks postoperatively, complete healing of the wound was observed without complications, and the patient had full range of motion of the elbow without pain. Despite major developments in the medical treatment of DM, ulcerative cutaneous lesions remain difficult to treat. Our experience suggests that the use of a transposition flap including the dorsal interosseous artery is suitable for the treatment of ulcerative lesions around the elbow in DM patients.


2019 ◽  
Vol 12 (2) ◽  
pp. 573-580
Author(s):  
Anna Katrina Dalton ◽  
King Man Wan ◽  
Deborah Gomes ◽  
Jenny Ma Wyatt ◽  
Martin K. Oehler

Vulval basal cell carcinomas (BCC) are an important differential diagnosis of painful, itchy vulval lesions, which can occur at all ages but commonly affect women in their senium. BCC tend to grow locally in an invasive and destructive pattern and seldom metastasize. Here we describe the rare case of inguinal metastasis in a 70-year-old woman with vulval BCC who was treated with radical hemivulvectomy, bilateral inguinal node sampling and adjuvant external beam radiotherapy. We discuss the clinical management of vulval BCC and provide an overview of the previously reported cases in the literature.


2020 ◽  
Vol 48 (9) ◽  
pp. 030006052093530
Author(s):  
Chao Gao ◽  
Feng-Chi Zhu ◽  
Bo-zhao Ma ◽  
Hao-Wen Jia ◽  
Jian Lu ◽  
...  

Neurilemmoma, also known as schwannoma or neurinoma, is a tumor that originates from neural sheath Schwann cells. Giant neurilemmomas derived from the retroperitoneum have rarely been reported. We herein describe a woman with a giant retroperitoneal neurilemmoma that was initially incorrectly diagnosed as an inflammatory abdominal mass. The tumor extended from the patient’s hypogastrium to her pelvic cavity and measured 20 × 15 × 10 cm. The tumor was excised via laparotomy and diagnosed as a retroperitoneal neurilemmoma through histological and immunohistochemical examination. Although rare, particularly in the giant form, neurilemmoma should be considered as an important differential diagnosis in patients with a retroperitoneal tumor or inflammatory abdominal mass. Complete excision should be considered for the potential cure of giant retroperitoneal neurilemmomas.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 509
Author(s):  
Maria Qadri ◽  
Qurban Hussain Sheikh ◽  
Mir Tahir Hussain Talpur ◽  
Uzair Yaqoob ◽  
Khalil Ullah Shabbir

Cutaneous tuberculosis (TB) can present in a number of ways, making it difficult to diagnose. It most commonly presents as scrofuloderma, which commonly affects the supra-clavicular region, axilla and the cervical region. All the different presentations of cutaneous TB should be known to clinicians, in order to diagnose it early. The objective of this article is to describe a case of scrofuloderma presenting with different cutaneous lesions at the same time, which were culture negative. We present a 23-year-old male with no known co-morbidities, presenting to us with fever and multiple swellings on the body. Cultures of pus and blood were negative for TB; GeneXpert detected the microorganism. Cutaneous TB, although a rare disease with wide spectrum of cutaneous lesions, should be considered in differential diagnosis of cold abscesses and nodules, especially of the head and neck region.


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