scholarly journals Transposition Flap for Cutaneous Lesion Coverage in Dermatomyositis

2020 ◽  
Vol 16 (3) ◽  
pp. 187-192
Author(s):  
Jaehyun Bae ◽  
Dongkeun Jun ◽  
Jeenam Kim ◽  
Hyungon Choi ◽  
Donghyeok Shin ◽  
...  
Keyword(s):  
Full Range ◽  
Cutaneous Lesion ◽  
Inflammatory Myopathy ◽  
Complete Healing ◽  
Cutaneous Lesions ◽  
Transposition Flap ◽  
Cutaneous Manifestations ◽  
Left Elbow ◽  
Interosseous Artery ◽  
Ulcerative Lesions

Dermatomyositis (DM) is an autoimmune inflammatory myopathy with some cutaneous manifestations. We present the case of a patient with a bone-depth skin ulceration on the elbow that was well healed with a transposition flap using a dorsal interosseous artery perforator. A 56-year-old man reported difficulties when climbing stairs and diffuse pain of unclear origin throughout his body that started 2 months previously. The patient was diagnosed with DM, and the department of plastic and reconstructive surgery was consulted for the management of an ulcerative skin lesion on the left elbow. The dorsal interosseous artery was first detected by vascular Doppler ultrasonography, and a transposition flap was designed including the pedicle. The flap was transposed to cover the bone exposure over the olecranon. At 4 weeks postoperatively, complete healing of the wound was observed without complications, and the patient had full range of motion of the elbow without pain. Despite major developments in the medical treatment of DM, ulcerative cutaneous lesions remain difficult to treat. Our experience suggests that the use of a transposition flap including the dorsal interosseous artery is suitable for the treatment of ulcerative lesions around the elbow in DM patients.

scholarly journals Ulcerative Lesions: A Rare Cutaneous Manifestation of Brucellosis

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Abbas Azadi ◽  
Payman Jafarpour Fard ◽  
Mohammad Almasian
Keyword(s):  
Differential Diagnosis ◽  
Antibiotic Treatment ◽  
Dairy Products ◽  
Rare Case ◽  
The Body ◽  
Cutaneous Lesions ◽  
Cutaneous Manifestations ◽  
Important Differential Diagnosis ◽  
Serology Test ◽  
Ulcerative Lesions

Brucellosis is a disease that is transmitted from animals to humans mainly via the consumption of unpasteurized dairy products, and it can involve any organ all over the body. Here, we report a significant rare case of brucellosis with cutaneous manifestations in a 52-year-old male patient whose disease was diagnosed via a serology test. The patient received standard antibiotic treatment, and his cutaneous lesions healed quickly. Although the cutaneous manifestations of brucellosis are exceedingly rare, in case of encountering ulcerative lesions and other cutaneous findings, particularly in endemic areas, infection with brucellosis should be kept in mind as an important differential diagnosis.

scholarly journals A clinical study of various cutaneous manifestations in neonates

2019 ◽  
Vol 5 (1) ◽  
pp. 8
Author(s):  
Shams Zia Usmani ◽  
Kshitij Saxena ◽  
Venkatarao Koti ◽  
Shrish Bhatnagar ◽  
Gaurav Paliwal ◽  
...  
Keyword(s):  
Neonatal Period ◽  
Cutaneous Lesion ◽  
Skin Lesions ◽  
Good Prognosis ◽  
Cutaneous Lesions ◽  
Cutaneous Manifestations ◽  
Medical College ◽  
Variable Nature ◽  
Detailed Assessment ◽  
Neonatal Skin

<p class="abstract"><strong>Background:</strong> Cutaneous manifestations are common in neonates. Transient and pathological neonatal dermatoses should be differentiated to avoid unnecessary treatment and thus considering the variable nature and severity of neonatal skin lesions, it is important to be aware of the transient skin lesions in newborn and to differentiate these from other serious conditions which will avoid unnecessary therapy to the neonates and the parents can be assured of good prognosis of these skin manifestations. The present study has been carried out to study the clinical pattern of cutaneous lesion in neonatal period.</p><p class="abstract"><strong>Methods:</strong> A total of 255 neonates from Department of Dermatology in collaboration of Department of Pediatrics, Era’s Lucknow Medical College and Hospital were evaluated for cutaneous manifestations. A detailed assessment regarding history, clinical examination and investigations were recorded and analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 255 neonates, 138 (54.1%) were males and 117 (45.9%) were females. The sex ratio (M:F) was 1.18. The most common dermatoses were physiological desquamation (54.1%) and mongolian spots (37.6%) followed by milia (19.6%), miliaria (14%), epstein pearls (10.2%).</p><p class="abstract"><strong>Conclusions:</strong> The physiological and transient cutaneous lesions are common are in neonates. Physiological cutaneous manifestations were quite frequent apart from birthmarks/congenital cutaneous manifestations. An understanding of these manifestations helps in managing and deciding the appropriate manifestation.</p>

scholarly journals A clinical study of cutaneous manifestations in neonates

2017 ◽  
Vol 3 (1) ◽  
pp. 130
Author(s):  
Ashok S. Hogade ◽  
Saranya D.
Keyword(s):  
Neonatal Period ◽  
Cutaneous Lesion ◽  
Skin Lesions ◽  
Consanguineous Marriage ◽  
Age Group ◽  
Cutaneous Lesions ◽  
Normal Delivery ◽  
Cutaneous Manifestations ◽  
Clinical Pattern ◽  
The People

<p class="abstract"><strong>Background:</strong> Various cutaneous manifestations are common in the neonatal period. Transient and pathological neonatal dermatoses should be differentiated to avoid unnecessary treatment and to relieve parent’s stress. The present study is being carried out to study the clinical pattern of cutaneous lesion during the neonatal period, to determine the frequency of various dermatoses i.e. physiological and pathological lesions in neonate along with appropriate management of cases.</p><p class="abstract"><strong>Methods:</strong> A total of 100 neonates from labour rooms and pediatric nursery of Basaveshwara general hospital, Kalaburagi were evaluated for cutaneous manifestations. All the relevant data regarding history, clinical examination and investigations were recorded and analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Of the 100 neonates, 56 (56%) were males and 44 (44%) were females, 72 (72%) were full term, 23 (23%) were pre-term and 5% were post term. Of these 78% newborns were born to multigravidae mothers, while 24% newborns born of consanguineous marriage had cutaneous lesions. The majority of newborns 54% were born through normal delivery. The largest number of babies with cutaneous lesions (72%) was seen in newborns of mothers in the age group of 20-29 years. The most common dermatoses were physiological scaling (18%) and Mongolian spots (20%) followed by milia (13%), miliaria (14%).</p><p><strong>Conclusions:</strong> The present study helps to understand the type and distribution of cutaneous lesions presenting in the early neonatal period in newborns.<strong> </strong>Majority of skin lesions were transient and did not need any medical treatment. Counselling the parents helped alleviate their significant psychological stress as well as play a role in creating awareness in the community and benefit the people at large.</p>

scholarly journals Single and Multiple Odontogenic Cutaneous Sinus Tracts

2020 ◽  
Vol 4 (11) ◽  
pp. 197-216
Keyword(s):  
Cutaneous Lesion ◽  
Treatment Strategies ◽  
Sinus Tract ◽  
Body Region ◽  
Nasolabial Fold ◽  
Cutaneous Lesions ◽  
Cutaneous Fistula ◽  
Cutaneous Manifestations ◽  
Second Molar ◽  
Cutaneous Sinus

Odontogenic cutaneous sinus tract (OCST) (synonyms: odontogenic cutaneous fistula, odontogenic subcutaneous granuloma, etc.) is an abnormal tube-shape formation which serves as a pathway for pus drainage from the locus of tooth–associated infection to the cutaneous lesion. OCST is a collective term and commonly is manifested in six cutaneous forms: as dimpling with fistula, cutaneous infiltration, nodule, suppurated nodule, abscess, or even cyst-like cutaneous formation. The purpose of this paper is to present the diverse clinical and radiological appearance (cone-beam computed tomography [CBCT] and ultrasound [US]) of single and multiple OCSTs based on the literature and our four cases. As long as limited publications present the ultrasound appearance of the OCSTs, we will focus on meticulous description of sonograms as well, giving a possibility for oral and maxillofacial surgeons to understand all advantages of that type of non-ionizing radiation diagnostics, avoiding misdiagnosis and mistreatment of OCSTs. Case 1: A 24-year-old male with OCST to the left mandibular region from the lower left first molar. Cutaneous lesion of OCST manifested as a transition stage from cutaneous infiltration to abscess. Case 2: A 41-year-old male with odontogenic cutaneous fistula of the right mandibular body region from the lower right second molar. It`s manifested as deep dimpling with active fistula. Case 3: A 45-year-old male with unilateral multiple OCSTs: 1) odontogenic cutaneous fistula of the left cheek from the left second maxillary molar and 2) a scar from a surgically treated OCST located in the projection of the left mandible from the tooth #3.6. Case 4: An 18-year-old male with OCST to left nasolabial fold and cheek from the upper left first molar. The pathology manifested as a subcutaneous abscess first and a nodule after the abscess lancing. These cases highlight the diverse cutaneous manifestations of the OCSTs. The US appearances of different parts of the OCST are presented, the popular terminology for the same cutaneous lesions are discussed, the new terms are proposed, and the treatment strategies based on histologic results are debated.

scholarly journals Cutaneous manifestations of COVID-19 in Mexican patients: A case series and review of literature

2021 ◽  
Vol 9 ◽  
pp. 2050313X2199719
Author(s):  
Juan Carlos Palomo-Pérez ◽  
Maria Elisa Vega-Memije ◽  
David Aguilar-Blancas ◽  
Erik González-Martínez ◽  
Lucia Rangel-Gamboa
Keyword(s):  
Respiratory Symptoms ◽  
Case Series ◽  
Signs And Symptoms ◽  
Skin Lesions ◽  
World Health ◽  
Medical Community ◽  
Atypical Pneumonia ◽  
Cutaneous Lesions ◽  
Cutaneous Manifestations ◽  
Mexican Patients

China officially recognized atypical pneumonia outbreak in December 2019; on 11 March 2020, the World Health Organization declared COVID-19 as a pandemic that is produced by a new coronavirus, named SARS-CoV-2, of rapid transmissibility, which can be asymptomatic, with mild to severe respiratory symptoms, and with cardiovascular, neurological, gastrointestinal, and cutaneous complications. Considering that the pandemic prolonged more than initially expected was prognostic, it is essential for the medical community to identify the signs and symptoms of COVID-19. Thus, this work’s objectives were to present cases of cutaneous lesions observed in COVID-19 Mexican patients. We register cutaneous lesions in COVID-19 patients referred from internal medicine and otorhinolaryngology services to dermatology. We presented four interesting cases with cutaneous lesions, including exanthema morbilliform, urticaria, chilblains, ecchymosis, and facial edema, and review the available literature. The most frequent cutaneous markers are rash, chilblains, and urticaria. Skin lesions may be the first manifestation of COVID-19, accompany initial respiratory symptoms, or appear during the disease course. Symptoms associated with vascular changes (livedo reticularis and vasculitis) are considered of poor prognosis.

scholarly journals Acanthamoeba spp. as Agents of Disease in Humans

2003 ◽  
Vol 16 (2) ◽  
pp. 273-307 ◽  
Author(s):  
Francine Marciano-Cabral ◽  
Guy Cabral
Keyword(s):  
Cerebrospinal Fluid ◽  
Cutaneous Lesion ◽  
Laboratory Diagnosis ◽  
Immune Defense ◽  
In Vitro Cultivation ◽  
Cutaneous Lesions ◽  
Trophozoite Stage ◽  
Biopsy Material ◽  
Pathogenic Potential

SUMMARY Acanthamoeba spp. are free-living amebae that inhabit a variety of air, soil, and water environments. However, these amebae can also act as opportunistic as well as nonopportunistic pathogens. They are the causative agents of granulomatous amebic encephalitis and amebic keratitis and have been associated with cutaneous lesions and sinusitis. Immuno compromised individuals, including AIDS patients, are particularly susceptible to infections with Acanthamoeba. The immune defense mechanisms that operate against Acanthamoeba have not been well characterized, but it has been proposed that both innate and acquired immunity play a role. The ameba's life cycle includes an active feeding trophozoite stage and a dormant cyst stage. Trophozoites feed on bacteria, yeast, and algae. However, both trophozoites and cysts can retain viable bacteria and may serve as reservoirs for bacteria with human pathogenic potential. Diagnosis of infection includes direct microscopy of wet mounts of cerebrospinal fluid or stained smears of cerebrospinal fluid sediment, light or electron microscopy of tissues, in vitro cultivation of Acanthamoeba, and histological assessment of frozen or paraffin-embedded sections of brain or cutaneous lesion biopsy material. Immunocytochemistry, chemifluorescent dye staining, PCR, and analysis of DNA sequence variation also have been employed for laboratory diagnosis. Treatment of Acanthamoeba infections has met with mixed results. However, chlorhexidine gluconate, alone or in combination with propamidene isethionate, is effective in some patients. Furthermore, effective treatment is complicated since patients may present with underlying disease and Acanthamoeba infection may not be recognized. Since an increase in the number of cases of Acanthamoeba infections has occurred worldwide, these protozoa have become increasingly important as agents of human disease.

scholarly journals Role of the autologous mesenchymal stem cells compared with platelet rich plasma on cicatrization of cutaneous wounds in diabetic mice

2016 ◽  
Vol 36 (7) ◽  
pp. 617-624
Author(s):  
Napoleão M. Argolo Neto ◽  
Ricardo J. Del Carlo ◽  
Betânia S. Monteiro ◽  
Nance B. Nardi ◽  
Pedro C. Chagastelles ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Platelet Rich Plasma ◽  
Cutaneous Lesion ◽  
Healing Time ◽  
Diabetic Mice ◽  
Cutaneous Lesions ◽  
Cutaneous Wounds ◽  
Autologous Mesenchymal Stem Cells ◽  
Treatment Of Wounds

Abstract: Chronic cutaneous lesions affect 15% of diabetic human patients and represent a risk 15 to 46 times larger of limb amputations compared to people with normal glycemia. It is assumed that half of these amputations could be prevented by early treatment of wounds, for example, with proper cell therapy. Objectives: In this study, the action of the autologous transplant of mesenchymal stem-cells (MSC) was evaluated compared to the treatment with autologous platelet rich plasma (PRP) in the cicatrization of cutaneous lesions induced in diabetic mice. These animals were previously treated with streptozootocin to induce diabetes mellitus and round wounds of 1.5cm in diameter were created in the posterior region. Diameters of the wounds and healing time were evaluated during 30 days and the results were submitted to variance analysis and Tukey's test average. It was noticed that the animals treated with MSC presented a more accelerated cicatrization of the cutaneous lesion than the animals treated with PRP. However, the treatment with PRP presented better results than just the daily asepsis of the lesions with saline or covering them with semi-permeable bandage. Besides, the use of semi-permeable bandage kept the cutaneous lesions of diabetic mice did not interfere negatively with cicatrization, proved to be harmless to use, but kept the cutaneous lesions more hydrated than the ones exposed to the environment.

scholarly journals Dermoscopy and Trichoscopy in Dermatomyositis—A Cross-Sectional Study

2022 ◽  
Vol 11 (2) ◽  
pp. 375
Author(s):  
Magdalena Żychowska ◽  
Adam Reich
Keyword(s):  
Diagnostic Technique ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Cutaneous Lesions ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Non Invasive ◽  
Inflammatory Dermatoses ◽  
Curved Vessels ◽  
Established Role

Background: (Video)dermoscopy is a non-invasive diagnostic technique that has a well-established role in dermatooncology. In recent years, this method has also been increasingly used in the assessment of inflammatory dermatoses. So far, little is known about the (video)dermoscopic features of dermatomyositis (DM). Methods: Consecutive patients with DM were included in the study and videodermoscopic assessments of the nailfolds, scalp, and active skin lesions were performed. Results: Fifteen patients with DM (10 women and 5 men) were included. Capillaroscopy showed elongated capillaries (90.9%), avascular areas (81.8%), disorganized vessel architecture (81.8%), tortuous capillaries (72.7%), dilated capillaries (72.7%), and hemorrhages (72.7%). The trichoscopic findings included linear branched vessels (80.0%), linear vessels (60.0%), linear curved vessels (53.3%), perifollicular pigmentation (40.0%), perifollicular erythema (33.3%), scaling (20.0%), white (20.0%) or yellow (20%) interfollicular scales, and white (20.0%) or pinkish (13.3%) structureless areas. Polymorphic vessels of an unspecific distribution and white or pink structureless areas were frequently observed under dermoscopy in cutaneous manifestations of DM, including Gottron’s papules and Gottron’s sign. Conclusions: Dermoscopy of the nailfolds (capillaroscopy), scalp (tricoscopy), and active cutaneous lesions may be of value in the preliminary diagnosis of DM.

scholarly journals Dermatological Manifestations in the Intensive Care Unit: A Practical Approach

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Mariona Badia ◽  
José Manuel Casanova ◽  
Lluís Serviá ◽  
Neus Montserrat ◽  
Jordi Codina ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Cutaneous Lesion ◽  
Skin Lesions ◽  
Intensive Treatment ◽  
Main Diagnosis ◽  
Systemic Diseases ◽  
Cutaneous Manifestations ◽  
Critical Patients ◽  
The Moment

Dermatological problems are not usually related to intensive medicine because they are considered to have a low impact on the evolution of critical patients. Despite this, dermatological manifestations (DMs) are relatively frequent in critically ill patients. In rare cases, DMs will be the main diagnosis and will require intensive treatment due to acute skin failure. In contrast, DMs can be a reflection of underlying systemic diseases, and their identification may be key to their diagnosis. On other occasions, DMs are lesions that appear in the evolution of critical patients and are due to factors derived from the stay or intensive treatment. Lastly, DMs can accompany patients and must be taken into account in the comprehensive pathology management. Several factors must be considered when addressing DMs: on the one hand, the moment of appearance, morphology, location, and associated treatment and, on the other hand, aetiopathogenesis and classification of the cutaneous lesion. DMs can be classified into 4 groups: life-threatening DMs (uncommon but compromise the patient's life); DMs associated with systemic diseases where skin lesions accompany the pathology that requires admission to the intensive care unit (ICU); DMs secondary to the management of the critical patient that considers the cutaneous manifestations that appear in the evolution mainly of infectious or allergic origin; and DMs previously present in the patient and unrelated to the critical process. This review provides a characterization of DMs in ICU patients to establish a better identification and classification and to understand their interrelation with critical illnesses.

Polymyositis and dermatomyositis

2010 ◽  
pp. 3692-3698
Author(s):  
John H. Stone
Keyword(s):  
Cytotoxic T Cells ◽  
Inflammatory Myopathy ◽  
Idiopathic Inflammatory Myopathy ◽  
Hla Class I ◽  
Muscle Enzymes ◽  
Calcinosis Cutis ◽  
Muscle Involvement ◽  
Cutaneous Manifestations ◽  
Associated Malignancy ◽  
Mechanic’S Hands

Polymyositis and dermatomyositis are two types of idiopathic inflammatory myopathy. The pathological findings in polymyositis suggest an HLA class I-restricted immune response mediated by cytotoxic T cells; dermatomyositis appears to be associated with humorally mediated destruction of muscle-associated microvasculature. Clinical features—polymyositis is characterized by symmetrical painless proximal muscle weakness that develops slowly, usually over weeks to months, and typically associated with significant elevation of serum creatine kinase and other muscle enzymes. The pattern of muscle involvement in dermatomyositis is clinically indistinguishable from that of polymyositis, but with cutaneous manifestations including Gottron’s sign, heliotrope rash, erythema, ‘mechanic’s hands’, periungual abnormalities, and calcinosis cutis. Extra-muscular features include interstitial lung disease (30% of cases), aspiration pneumonia, and associated malignancy (polymyositis 9%, dermatomyositis 15%)....

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