scholarly journals Carotid Paraganglioma in Adolescence-Clinical Picture-Surgical Technique and Review of the Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Thomas Kotsis ◽  
Panagitsa Christoforou ◽  
Constantinos Nastos
Keyword(s):  
Differential Diagnosis ◽  
Head And Neck ◽  
Carotid Body ◽  
Case Reports ◽  
Outpatient Service ◽  
Young Patients ◽  
Neuroendocrine Cells ◽  
Neck Tumors ◽  
Branchial Cleft ◽  
Age Range

Paraganglia are clusters of cells originating from the neural crest with histological and cytochemical characteristics of neuroendocrine cells. Paragangliomas of the head and neck represent less than 0.5% of all head and neck tumors and they usually occur between the ages of 40 and 50. Paragangliomas in childhood and in adolescence are extremely rare; only 23 case reports have been reported in the recent literature. In childhood, the estimation of malignant potential is 3–10%; therefore, early diagnosis and treatment of carotid body paragangliomas are mandatory. However, due to the rarity of these lesions in young patients, they are often not included in the differential diagnosis of solid masses in the neck area, a fact that may lead to misdiagnosis or delay in treatment. We present, herein, two extremely rare cases of patients in adolescence who were diagnosed with a carotid body paraganglioma and were treated surgically in our unit. One of the patients was diagnosed and treated at the age of 15 years while the other had a long-standing tumor in the neck that was followed up by a general surgery outpatient service as a branchial cleft cyst at the age of 15 years and was eventually treated surgically 8 years later. Carotid body tumor was not considered in the initial differential diagnosis because of its rarity at this age range.

scholarly journals Review and Updates of Immunohistochemistry in Selected Salivary Gland and Head and Neck Tumors

2015 ◽  
Vol 139 (1) ◽  
pp. 55-66 ◽  
Author(s):  
Shaobo Zhu ◽  
Conrad Schuerch ◽  
Jennifer Hunt
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Literature Review ◽  
Head And Neck ◽  
Head And Neck Tumors ◽  
Data Sources ◽  
Diverse Group ◽  
Immunohistochemical Markers ◽  
Neck Tumors ◽  
Practice Experience

Context Immunohistochemistry is a useful tool for diagnosing salivary gland and head and neck tumors. Objective To review immunohistochemical markers, which can aid in the diagnosis of selected salivary gland and head and neck tumors. Data Sources Literature review and authors' personal practice experience. Conclusions Salivary gland and head and neck tumors include a large diverse group of tumors with complex and overlapping histologic features. Immunohistochemistry plays an important role in resolving the differential diagnosis of some salivary gland and head and neck tumors and can provide information for the prognosis of certain tumors.

scholarly journals Dermoid Cysts of the Floor of the Mouth: Two Case Reports

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Christos Makos ◽  
George Noussios ◽  
Marinos Peios ◽  
Spyridon Gougousis ◽  
Pantelis Chouridis
Keyword(s):  
Differential Diagnosis ◽  
Sebaceous Gland ◽  
Case Reports ◽  
Branchial Arch ◽  
Clinical Findings ◽  
The Body ◽  
Embryonic Cells ◽  
Floor Of The Mouth ◽  
Neck Tumors ◽  
Gland Duct

Dermoid cysts in the floor of the mouth may be congenital or acquired. The congenital form, according to the main theory, originates from embryonic cells of the 1st and 2nd branchial arch. The acquired form may be due to traumatic or iatrogenic causes and as a result of the occlusion of a sebaceous gland duct. Its occurrence is less and is estimated to be from 1.6 to 6.4% of the dermoid cysts of the body in adults and 0.29% of the head and neck tumors occurring in children. They may also be classified as anatomical and histological. Anatomically, they are divided into median genioglossal, median geniohyoid, and lateral cysts, while histologically they are divided into epidermoid, dermoid cysts and teratomas. Clinically, a distinction between supra and inferior type as well as between central and lateral type is proposed in relation to themylohyoidmuscle and themidline, respectively. Histologically, an estimation of dermoid, epidermoid, and teratoid cysts is reported. Enucleation via intraoral and/or extraoral approach is the method of treatment. Two case reports of dermoid cysts in the floor of the mouth are presented in this paper, and an evaluation with regard to pathology, clinical findings, differential diagnosis, and treatment is discussed.

Positron emission tomographic imaging with11C-choline in differential diagnosis of head and neck tumors: comparison with18F-FDG PET

2004 ◽  
Vol 18 (5) ◽  
pp. 409-417 ◽  
Author(s):  
Nasim Khan ◽  
Noboru Oriuchi ◽  
Hiroshi Ninomiya ◽  
Tetsuya Higuchi ◽  
Hideo Kamada ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Head And Neck ◽  
Fdg Pet ◽  
Tomographic Imaging ◽  
Head And Neck Tumors ◽  
Positron Emission Tomographic ◽  
Neck Tumors ◽  
Positron Emission

Cystic Adventitial Disease of the Iliofemoral Artery: Case Reports and a Short Review

Vascular ◽  
2006 ◽  
Vol 14 (3) ◽  
pp. 169-172 ◽  
Author(s):  
Ravul Jindal ◽  
Addie Majed ◽  
Mohamad Hamady ◽  
John H. Wolfe
Keyword(s):  
Differential Diagnosis ◽  
Rare Disease ◽  
Case Reports ◽  
Young Patients ◽  
Short Review ◽  
Young Males ◽  
Leg Ischemia

Cystic adventitial disease is a rare disease affecting mainly young males. We describe two patients with this disease affecting the iliofemoral artery. These reports reemphasize the importance of keeping cystic adventitial disease as a differential diagnosis in young patients who present with leg ischemia.

scholarly journals MON-249 SDHD Mutation: Nonfunctional Paragangliomas Presenting as Bilateral Carotid Body Tumors with Syncope

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
David LaChance ◽  
Thanh Duc Hoang ◽  
Mohamed K M Shakir
Keyword(s):  
Family History ◽  
Head And Neck ◽  
Carotid Body ◽  
Case Reports ◽  
Neck Region ◽  
Carotid Body Tumor ◽  
Sdhd Mutation ◽  
Bilateral Carotid ◽  
History Of ◽  
Carotid Body Tumors

Abstract SDHD Mutation: Nonfunctional paragangliomas presenting as bilateral carotid body tumors with syncope Background: A mutation of the SDHD gene is associated with hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndromes which most commonly originate in the head and neck region, and usually form in the carotid body. Paragangliomas (PGL) can be secretory or non-secretory with about 95% of head and neck PGL being non-secretory. They can rarely present with symptoms due to compression, however, as in this case of a 29 year-old female presenting with syncope. Clinical Case: A 29 year-old female presented for evaluation after syncope. She had a syncopal event and fell down while walking in her home. Syncope was preceded by about 15 minutes of flushing, nausea and palpitations. She reported similar episodes once weekly in the preceding months, which generally lasted an hour. Initial workup included normal vital signs at presentation, normal ECG and echocardiogram, normal TFT, CBC, complete metabolic panel. Subsequent head/neck CT revealed bilateral masses in the carotid bifurcations consistent with carotid body tumors. Further history revealed a family history of bilateral carotid body tumors in her father which had never been evaluated. Plasma and urine metanephrines were normal. She underwent carotid body tumor excision. The left carotid body tumor was successfully excised and pathology revealed a paraganglioma with positive synaptophysin and chromogranin stains. Genetic testing revealed an SDHD (succinate dehydrogenase complex subunit D) gene mutation. Repeat biochemical assessment 4 months later was again negative and patient remained asymptomatic postoperatively. Conclusion: Paragangliomas can be secretory or non-secretory with about 95% of head and neck paragangliomas being non-secretory, as in this case. Symptoms can arise from catecholamine hypersecretion, which generally presents as hypertension, headaches, diaphoresis, flushing, anxiety or palpitations, and can be episodic or sustained, or mass effect. Syncope as a presenting symptom is rare, however, and has not been quantified but only reported in case reports. The exact etiology of syncope in our patient is not clear. Hereditary PGL/PCC syndromes should be suspected in any individual with multiple, recurrent, early-onset (age less than 45 years) or family history of PGL/PCC, as these syndromes are inherited in an autosomal dominant manner.

Malignant tumours as a rare cause of recurrent thrombophlebitis of the great saphenous vein

Phlebologie ◽  
2008 ◽  
Vol 37 (06) ◽  
pp. 297-300
Author(s):  
N. König ◽  
H. J. Stark ◽  
P.-M. Baier
Keyword(s):  
Differential Diagnosis ◽  
Saphenous Vein ◽  
Great Saphenous Vein ◽  
Case Reports ◽  
Malignant Tumours ◽  
Nerve Sheath Tumour ◽  
Below The Knee ◽  
Nerve Sheath ◽  
Unfavourable Prognosis ◽  
Peripheral Nerve Sheath Tumour

SummaryWe present two case reports concerning patients who had to undergone surgical treatment according tp the diagnosis of thrombophlebitis with insufficiency of the greater saphenous vein and putative encapsulated haematoma in the lower left leg area. During the operation we found tumours with urgent suspicion of malignancy. The histological examination revealed the diagnosis of mesenchymal chondrosarcoma and malignant peripheral nerve sheath tumour which are extremely malignant, but very rare neoplasmas with unfavourable prognosis. Conclusion: Since both types of tumours are often located below the knee, phlebotomists and vascular surgeons should take them into account as differential diagnosis.

Differential diagnosis of elevated liver enzymes: case reports

2008 ◽  
Vol 46 (05) ◽  
Author(s):  
T Korom ◽  
I Nagy ◽  
É Csajbók ◽  
T Wittmann
Keyword(s):  
Differential Diagnosis ◽  
Liver Enzymes ◽  
Case Reports ◽  
Elevated Liver Enzymes
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