scholarly journals The Association of Fasting C-peptide with Corneal Neuropathy in Patients with Type 2 Diabetes

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Anju Zuo ◽  
Chuan Wang ◽  
Lili Li ◽  
Jingru Qu ◽  
Juan Cao ◽  
...  
Keyword(s):  
Correlation Analysis ◽  
Pearson Correlation ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
C Peptide ◽  
Duration Of Diabetes ◽  
Corneal Nerve ◽  
And Gender ◽  
The Relationship

Purpose. Damage to corneal nerve fibers has been demonstrated in people with type 2 diabetes mellitus (T2DM) that further progresses with increasing severity of diabetic peripheral neuropathy. However, the role of C-peptide in corneal nerve damage has not been reported in T2DM. The present study investigated the relationship of fasting C-peptide levels with corneal neuropathy evaluated by corneal confocal microscopy (CCM) in patients with T2DM. Methods. 160 T2DM patients (72 females) aged 34-78 with duration ranging from 0 to 40 years underwent CCM to measure corneal nerve fiber length (CNFL), corneal nerve fiber density (CNFD), and corneal nerve branch density (CNBD). Pearson correlation analysis and multiple linear regression analysis were used to explore the association of fasting C-peptide levels with corneal nerve parameters. Partial correlation analysis (adjusted for age and gender) was also conducted to analyze the correlation of metabolic indexes with these three corneal nerve parameters. The relationship between fasting C-peptide levels and duration of diabetes was also explored by Pearson correlation analysis. Results. With an increase in fasting C-peptide levels, the values of CNFL, CNFD, and CNBD also showed a corresponding trend for an increase. Partial correlation analysis revealed that fasting C-peptide levels were positively associated with CNFL ( r = 0.245 , P = 0.002 ), CNFD ( r = 0.180 , P = 0.024 ), and CNBD ( r = 0.214 , P = 0.008 ) after adjusting for age and gender. Using multiple linear regression analysis, fasting C-peptide levels were also closely associated with CNFL ( P = 0.047 ) and CNBD ( P = 0.038 ) after multiple adjustments. However, this association disappeared after further adjusting for duration of diabetes. Further analysis indicated that fasting C-peptide levels declined with duration of diabetes ( r = − 0.267 , P = 0.001 ). Conclusions. C-peptide was closely associated with corneal neuropathy and disease duration in T2DM. C-peptide levels might be both an indicator of beta-cell function and a marker of disease severity (such as diabetic corneal neuropathy) and duration.

scholarly journals Association of Serum Adropin Concentrations with Diabetic Nephropathy

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Wenchao Hu ◽  
Li Chen
Keyword(s):  
Regression Analysis ◽  
Diabetic Nephropathy ◽  
Energy Homeostasis ◽  
Pearson Correlation ◽  
Linear Regression Analysis ◽  
Regulatory Protein ◽  
Multiple Linear Regression Analysis ◽  
Lower Serum ◽  
Urine Albumin

Objective. Adropin is a newly identified regulatory protein encoded by the Enho gene and is critically involved in energy homeostasis and insulin sensitivity. This study aims to determine the correlation of serum adropin concentrations with diabetic nephropathy (DN).Methods. This study consisted of 245 patients with type 2 diabetes mellitus (T2DM) and 81 healthy subjects. Then T2DM patients were divided into normoalbuminuria, microalbuminuria, and macroalbuminuria subgroups based on urine albumin to creatinine ratio (ACR).Results. T2DM patients showed significantly lower serum adropin concentrations than those in the controls. T2DM patients with macroalbuminuria had significantly decreased serum adropin concentrations compared with the other three groups. In addition, T2DM patients with microalbuminuria showed lower serum adropin concentrations than those in patients with normoalbuminuria. Logistic regression analysis showed that serum adropin was correlated with decreased risk of developing T2DM and DN. Pearson correlation analysis indicated that serum adropin was negatively correlated with body mass index (BMI), blood urea nitrogen, creatinine, and ACR and positively correlated with glomerular filtration rate. Furthermore, multiple linear regression analysis showed that BMI and ACR were negatively correlated with serum adropin levels.Conclusion. Serum adropin concentrations are negatively associated with renal function. Adropin may be implicated in the pathogenesis of DN development.

scholarly journals Age, Gender, Attitudes and Motivation as Predictors of Willingness to Listen in L2

2019 ◽  
Vol 10 (4) ◽  
pp. 72
Author(s):  
Ahmet Selçuk Akdemir
Keyword(s):  
Regression Analysis ◽  
Pearson Correlation ◽  
Linear Regression Analysis ◽  
Efl Learners ◽  
Personal Variables ◽  
Meaningful Relationship ◽  
Gender And Age ◽  
And Gender ◽  
The Relationship ◽  
Attitude And Motivation

The aim of the current research is to investigate the relationship between the attitudes and motivation of EFL learners and their willingness to listen (WTL); possible effects of age and gender on EFL learners’ WTL, attitude and motivation. A quantitative study was designed in which 239 participants, intermediate level EFL learners at a public university, took a set of instruments, namely a reduced version of the AMTB, mini-AMTB, and WTL scale in Likert type. The participants were also asked to specify their gender and age during data collection procedure. Data was analysed using SPSS 24.0. Percentage and frequency analyses, independent samples t-test, Kruskal Wallis H test, Pearson correlation analysis and simple linear regression analysis were employed in data analysis phase. The results of the study showed that gender affects EFL learners’ attitudes and motivation while age has no effect on attitudes and motivation; also it was found that there is a positive and meaningful relationship between mini-AMTB and WTL scores of the participants. According to the findings of the current study the predictive power of mini-AMTB of WTL has been found statistically meaningful. The findings have revealed that there is a positive and meaningful relationship between mini-AMTB and WTL scores of the participants. Gender affects EFL learners’ attitudes and motivation as female participants’ mini-AMTB scores were found higher than those of male participants. Also a meaningful relationship between mini-AMTB and WTL has been found according to regression analysis. The paper concludes with implications for further research to investigate the WTL in various contexts with other personal variables.

Elevated serum preptin concentrations in patients with diabetic nephropathy

2019 ◽  
Vol 67 (7) ◽  
pp. 1048-1052 ◽  
Author(s):  
Rui Wang ◽  
Aili Xue ◽  
Wenjian Zheng ◽  
Linchuan Wang ◽  
Fei Yan ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Diabetic Nephropathy ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Elevated Serum ◽  
Multiple Linear Regression Analysis ◽  
Urine Albumin ◽  
Acarbose Treatment ◽  
And Gender

Preptin is a peptide synthesized and secreted accompanied with insulin from pancreatic β cells. Here, we tested the hypothesis that serum preptin concentrations are correlated with diabetic nephropathy (DN). Our study was performed in a population of 234 patients with type 2 diabetes mellitus (T2DM) and 78 healthy subjects. Patients with T2DM were divided into three groups: normoalbuminuria group (DN0, n=106), microalbuminuria group (DN1, n=90), and macroalbuminuria group (DN2, n=38) according to urine albumin to creatinine ratio (ACR). Serum preptin concentrations were significantly increased in the three T2DM subgroups than those in the controls. DN2 group showed significantly higher serum preptin concentrations compared with DN0 and DN1 groups. Moreover, DN1 group had higher serum preptin concentrations than DN0 group. Serum preptin was correlated with a higher risk of T2DM and DN after logistic regression analysis. Simply linear regression analysis demonstrated a positive correlation between serum preptin and gender, body mass index (BMI), blood urea nitrogen, creatinine, ACR, and a negative correlation between serum preptin and glomerular filtration rate, metformin, acarbose treatment. Gender, BMI, and ACR were still positively correlated with serum preptin after multiple linear regression analysis. Our findings indicate that serum preptin concentrations are associated with renal function and DN.

scholarly journals Employees’ Perception of School Leaders’ Efficacy and its Impact on their Adaptive Performance

2020 ◽  
Vol 7 (1) ◽  
pp. 55
Author(s):  
Farhat Munir ◽  
M. Abiodullah ◽  
Faiza Aslam
Keyword(s):  
Regression Analysis ◽  
Positive Relationship ◽  
Pearson Correlation ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Adaptive Performance ◽  
Significant Positive Relationship ◽  
Administrative Employees ◽  
High Level ◽  
The Relationship

The fast-paced change in schools demands high level of adaptability. Several factors have been explored through research that affects employees’ adaptability. The purpose of this study was to explore the relationship between employees’ perception of leaders’ efficacy and its impact on their adaptive performance. A sample of 266 academic & administrative employees was randomly selected from 50 private secondary schools of Lahore Pakistan. Pearson correlation and multiple linear regression analysis were run for data analysis and significant positive relationship was found between employees’ perception of leaders’ efficacy and their adaptive performance.

scholarly journals Fear of COVID-19 and Its Association With Health Literacy in Elderly Patients

2021 ◽  
Vol 8 ◽  
pp. 237437352110565
Author(s):  
Fedayi Yağar
Keyword(s):  
Health Literacy ◽  
Elderly Patients ◽  
Smoking Status ◽  
Pearson Correlation ◽  
Linear Regression Analysis ◽  
The Elderly ◽  
Multiple Linear Regression Analysis ◽  
Pearson Correlation Analysis ◽  
Literacy Scores ◽  
The Relationship

One of the groups most negatively affected by the epidemic process has been the elderly patients. In this process, it is of great importance to determine the fear levels of the patients and to evaluate the factors that may be related. With this approach, this study aimed to examine the relationship between the fear of COVID-19 and health literacy scores of elderly patients living in Kahramanmaraş City, Turkey. Another aim of the study was to investigate whether the participants’ COVID-19 fear change according to various socio-demographic characteristics. The convenience sampling method were used and 266 of valid samples were collected. Descriptive statistics, t-test, ANOVA, Pearson correlation analysis, simple and multiple linear regression analysis techniques were used. The results obtained from the study showed that COVID-19 fear status of the participants were moderate while the health literacy scores were low. Higher health literacy was associated with lower fear of COVID-19. In addition, it was determined that the fear of COVID-19 showed statistically significant differences according to education level, insurance status, smoking status, follow the news status and marital status. As a result, it has been observed that the level of health literacy can be effective in protecting elderly patients from fear. Longitudinal studies have been proposed to determine whether this relationship is causal or not.

scholarly journals THE INVESTIGATION OF THE INFLUENCE OF PSYCHOLOGICAL CONTRACT TYPES ON ORGANIZATIONAL CITIZENSHIP BEHAVIOUR

2019 ◽  
pp. 365
Author(s):  
Ivana Simić ◽  
Biljana Đorđević ◽  
Sandra Milanović
Keyword(s):  
Regression Analysis ◽  
Organizational Citizenship ◽  
Psychological Contract ◽  
Positive Impact ◽  
Pearson Correlation ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Positive Relation ◽  
The Relationship ◽  
Organizational Performances

Organizational citizenship behaviour represents the behaviour of the employees that goes beyond their duties. This type of behaviour from the perspective of employer is very desirable since it produces many positive consequences regarding individual and the overall organizational performances. However, readiness of the employees to exert this type of behaviour is influenced by many factors. One of the most important is fulfilment of employees’ psychological contract. Since that there are two basic forms of contracts, relational and transactional, the aim of this paper is to investigate the relationship between these types of psychological contract and organizational citizenship behaviour. For the purpose of testing proposed hypothesis, t-test, Pearson correlation and multiple linear regression analysis were applied. The results showed that there is a positive relation and positive impact of relational psychological contract on the organizational citizenship behaviour, which was not the case when it was about the transactional contract.

scholarly journals Association of Triglyceride-Glucose Index with the Incidence of Ketoacidosis in Chinese Children with Type 1 Diabetes

2021 ◽  
Author(s):  
Long Gao ◽  
Xinhui Wang ◽  
Jianbo Shu ◽  
Mingying Zhang ◽  
Xiufang Zhi ◽  
...  
Keyword(s):  
Positive Impact ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Clinical Prognosis ◽  
Tyg Index ◽  
Index Group ◽  
Triglyceride Glucose Index ◽  
The Relationship

Abstract Objective: The relationship between triglyceride-glucose index (TyG index) and the prevalence of type 2 diabetes mellitus (T2DM) has been confirmed by former studies. However, it remains uncertain whether TyG index has a predictive value in T1DM patients with diabetic ketoacidosis (DKA).Methods: The study retrospectively enrolled 143 patients ((boys/girls = 60/83) with T1DM in the Endocrine inpatient wards of Tianjin Children’s Hospital from June 2017 to May 2019.TyG index was calculated as follows: ln[fasting triglycerides (mg/dL)×fasting plasma glucose (mg/dL)/2]. These patients stratifed by the optimal cut-off point of TyG index were divided into the lower TyG index group (n=73) and higher TyG index group (n=70).Results: TyG index and related lipid parameters were significantly higher in patients with DKA compared with those without. Compared with patients in lower TyG index group, those with higher TyG index seemed to be younger. Multiple linear regression analysis showed that increase of TC (95%CI: 0.018~0.568, p=0.037) level and decrease of T3(95%CI:-2.314~-0.668,p=0.001) level were associated with the risk of higher TyG index. A linear equation was obtained between TC, T3 and TyG index (TyG index=10.226+0.299*TC-1.384*T3, R2=0.481). Conclusions: Increased TyG index is a significant predictor of DKA in children with T1DM. Higher TC and lower T3 levels were associated with higher TyG index. Further studies need to be conducted to determine whether interventions for TyG index have a positive impact on improving clinical prognosis.

scholarly journals Correlation analysis of epicardial adipose tissue thickness, C-reactive protein, interleukin-6, visfatin, juxtaposed with another zinc finger protein 1, and type 2 diabetic macroangiopathy

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Yuan-Yuan Gong ◽  
Hai-Ying Peng
Keyword(s):  
Correlation Analysis ◽  
Zinc Finger Protein ◽  
Pearson Correlation ◽  
Statistical Significance ◽  
Healthy Control Group ◽  
Control Group ◽  
Diabetes Group ◽  
Reactive Protein ◽  
Healthy Control

Abstract Background To investigate the correlation between the thickness of epicardial adipose tissue (EAT), C-reactive protein (CRP), interleukin (IL) -6, visfatin, juxtaposed with another zinc finger protein 1 (JAZF1) and type 2 diabetic mellitus (T2DM) macroangiopathy. Methods The study enrolled 82 patients with T2DM with macroangiopathy (the Complication Group), and 85 patients with T2DM (the Diabetes Group) who were admitted to Shandong Provincial Third Hospital from February 2018 to February 2020. In addition, 90 healthy people who underwent physical examination at the same hospital during the same period were enrolled (the Healthy Control Group). Age, gender, height, weight, waist circumference (WC), hip circumference (HC), diabetic course and therapeutic drugs, waist hip ratio (WHR), and body mass index (BMI) were recorded and calculated. Results The baseline characteristics of the three groups were comparable, and the diabetic course of the Complication Group and the Diabetes Group was not significantly different (P > 0.05). The WHR of the Complication Group was higher than that of the Diabetes Group and the Healthy Control Group, with statistical significance (P < 0.05). The FPG, 2hPG, HbA1C, CRP, IL-6, Visfatin, JAZF1, HOMA-IR, EAT thickness, and baPWV of the Complication Group were all higher than those of the Diabetes Group and the Healthy Control Group (P < 0.05, respectively). The JAZF1 and FIns of the Complication Group and Diabetes Group were lower than those of the Healthy Control Group, and JAZF1 of the Complication Group was lower than the Diabetes Group with statistical significance (P<0.05, respectively). Pearson correlation analysis showed that the EAT thickness was positively correlated with CRP, IL-6, visfatin, and JAZF1 (r = 0.387, 0.451, 0.283, 0.301, respectively, all P<0.001). Pearson correlation analysis showed that baPWV was positively correlated with EAT thickness, CRP, IL-6, visfatin, and JAZF1 (r = 0.293, 0.382, 0.473, 0.286, respectively, all P < 0.001). Multivariate stepwise regression analysis showed that FPG, 2hPG, HbA1C, CRP, IL-6, visfatin, JAZF1, and EAT thickness were independent risk factors that affected T2DM macroangiopathy. Conclusions Clinical monitoring and treatment of T2DM macroangiopathy can use CRP, IL-6, Visfatin, JAZF1, and EAT thickness as new targets to delay the progression of the disease. Further research on the relationship between the above factors and the pathogenesis of T2DM macroangiopathy may be helpful provide new treatment strategies.

scholarly journals Modelling the Additivity of Perceived Exertion in Symmetric, Mid-Sagittal Lifting

1994 ◽  
Vol 38 (10) ◽  
pp. 621-625 ◽  
Author(s):  
Brian D. Lowe
Keyword(s):  
Perceived Exertion ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Whole Body ◽  
Coefficient Of Determination ◽  
Perceived Effort ◽  
Repetitive Lifting ◽  
The Relationship ◽  
Whole Body Exertion ◽  
Lifting Task

Psychophysical approaches to quantifying perceived effort have been used to evaluate the physical demand of many industrial work activities. An experiment was conducted to examine the relationship between ratings of whole-body perceived exertion and differentiated, regional ratings of exertion. The Borg, CR-10 scale was used by 16 subjects performing a simulated repetitive lifting task. Ratings of perceived exertion were obtained for the arms, legs, torso, and central (cardiorespiratory) effort sensations as well as a rating of overall, whole-body exertion. A multiple linear regression analysis was used to predict the whole-body rating of exertion from the differentiated ratings in lifting tasks using both a squat and stoop posture. In the stoop posture condition the coefficient of determination between whole-body perceived exertion and the model including arm, torso, and central ratings was R2=0.81. In the squat posture condition, the final regression model predicting whole-body exertion contained only the rating from the legs (R2 = 0.62). Differentiated ratings explained the majority of the variance in whole-body perceived exertion for squat and stoop lifting tasks.

scholarly journals Association of Plasma Myeloperoxidase Level with Risk of Coronary Artery Disease in Patients with Type 2 Diabetes

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Ping Song ◽  
Jin Xu ◽  
Yongfeng Song ◽  
Shiliang Jiang ◽  
Haitao Yuan ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Logistic Analysis ◽  
Artery Disease

Aims. This study aimed to investigate whether the change of plasma myeloperoxidase (MPO) level would be associated with the incidence of coronary artery disease (CAD) among diabetic patients.Methods. 339 patients with type 2 diabetes mellitus (DM) underwent coronary angiography. Of them, 204 cases had CAD and were assigned to CAD group and 135 cases without CAD were assigned to non-CAD group.Results. Compared to non-CAD group, CAD group had higher level of plasma MPO (p<0.01). Multiple linear regression analysis showed that plasma MPO level was correlated with Gensini score. Multiple logistic analysis showed that the odds ratios for CAD across increasing tertiles of MPO level were 1.191 (0.971–1.547) and 1.488 (1.115–2.228) (p=0.048,p=0.009versus 1st tertile of MPO level, resp.) by adjusting for age, sex, and other conventional risk factors for CAD. The subjects were stratified into nine groups according to tertiles of MPO and HbA1c. The odds ratio for CAD was significantly higher in group with highest levels of MPO and HbA1c (OR = 4.08,p<0.01).Conclusion. Plasma MPO level was positively correlated with the degree of coronary artery stenosis in type 2 diabetic patients, and increasing blood glucose might amplify the association between MPO and CAD.

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