scholarly journals Silicone Oil Adhesion to Hydrophobic Acrylic Intraocular Lenses: A Comparative Laboratory Study of a New versus an Established Hydrophobic Acrylic Intraocular Lens Material

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Gerd U. Auffarth ◽  
Hui Fang ◽  
Qiang Wang ◽  
Fritz Hengerer ◽  
Ramin Khoramnia ◽  
...  
Keyword(s):  
Intraocular Lens ◽  
Room Temperature ◽  
Silicone Oil ◽  
Total Surface Area ◽  
Intraocular Lenses ◽  
Aqueous Sodium Chloride Solution ◽  
In Vitro Assessment ◽  
Lens Material ◽  
Hydrophobic Acrylic

Background. In vitro assessment of silicone oil adhesion to a new hydrophobic acrylic intraocular lens (IOL) material, the Clareon model CNA0T0, compared with the established AcrySof model SN60WF was carried out. Methods. Silicone oil adhesion was assessed for two types of IOLs, Clareon CNA0T0 (n = 10) and AcrySof SN60WF (n = 10). Lenses were immersed in an aqueous sodium chloride solution for 12 hours and then incubated at room temperature in silicone oil for 12 hours. The lenses were washed with distilled water and photographed at 25x magnification using a microscope. The percent coverage was calculated by dividing the area of oil coverage by the total surface area of the lens. Results. Silicone oil adhesion to the surface of the CNA0T0 lens ranged from 4% to 22%, with a mean ± SD coverage of 8% ± 4%. Silicone oil adhesion to the surface of the SN60WF lens ranged from 1% to 17%, with a mean coverage of 9% ± 4%. The silicone oil adhesion of CNA0T0 was equivalent to that of SN60WF ( P > 0.05 ). Conclusions. The new Clareon model CNA0T0 IOL has silicone oil adhesion and interaction that are equivalent to the established AcrySof IOL.

scholarly journals Microscopic Characteristics of Late Intraocular Lens Opacifications

2020 ◽  
Author(s):  
Piotr Kanclerz ◽  
Timur Mert Yildirim ◽  
Ramin Khoramnia
Keyword(s):  
Intraocular Lens ◽  
Room Temperature ◽  
English Language ◽  
Critical Issue ◽  
Intraocular Lenses ◽  
Alizarin Red ◽  
Younger Patients ◽  
X Ray ◽  
International Laboratory ◽  
Hydrophobic Acrylic

Context.— The increases in overall life expectancy and in lens surgeries performed on younger patients have resulted in a significant increase in the anticipated duration of artificial intraocular lenses (IOLs) in the eye. Thus, the physicochemical properties of the IOL become a critical issue, and several types of postoperative IOL opacifications have been reported. Objective.— To describe the microscopic characteristics of opacified IOLs. Glistenings and subsurface nanoglistenings are fluid-related phenomena developing mainly in hydrophobic acrylic IOLs and are associated with aqueous influx into the IOL matrix. Calcification presents in hydrophilic acrylic or silicone IOLs as deposits of hydroxyapatite or other phases of calcium. Snowflake degeneration is less common, and it manifests in older polymethyl methacrylate IOLs. Data Sources.— PubMed and ScienceDirect databases were searched for the following keywords: intraocular lens, IOL, cataract surgery, phacoemulsification, opacification, glistening, subsurface nanoglistenings, calcification, snowflake degeneration. English-language articles published up to October 15, 2019 were included in the study. The manuscript contains mainly a literature review; however, it was supplemented with original investigations from the David J. Apple International Laboratory for Ocular Pathology Conclusions.— Glistenings and subsurface nanoglistenings should be evaluated in hydrated state and at room temperature; they manifest as microvacuoles sized from 1.0 to greater than 25.0 μm and less than 200 nm, respectively. Calcification deposits are situated on or underneath the surface of the IOL and can be stained with a 1% alizarin red solution or with the von Kossa method. Snowflake degeneration manifests as “particles” or “crystals,” causing whitish IOL discoloration. Scanning electron microscopy or energy dispersive X-ray spectroscopy may improve the diagnostic accuracy.

Assessment of new-generation glistening-free hydrophobic acrylic intraocular lens material

2012 ◽  
Vol 38 (7) ◽  
pp. 1271-1277 ◽  
Author(s):  
Christophe Pagnoulle ◽  
Dimitriya Bozukova ◽  
Laure Gobin ◽  
Virginie Bertrand ◽  
Marie-Claire Gillet-De Pauw
Keyword(s):  
Intraocular Lens ◽  
New Generation ◽  
Lens Material ◽  
Hydrophobic Acrylic

scholarly journals Late Opacification of Foldable Intraocular Lenses

2012 ◽  
Vol 46 (2) ◽  
pp. 95-97
Author(s):  
Nishant Gupta ◽  
Jagat Ram ◽  
Manish Chaudhary ◽  
Jaspreet Singh Sukhija ◽  
Jaidrath Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Intraocular Lens ◽  
Manufacturing Process ◽  
Case Series ◽  
Intraocular Lenses ◽  
Hydrophobic Acrylic ◽  
Iol Exchange

ABSTRACT Objective To report opacification of hydrophilic acrylic and silicone foldable intraocular lenses (IOL). Designs Case series. Participants Five patients with IOL opacification. Results We report five eyes of five patients with late opacification of the intraocular lens (IOL). Three patients had hydrophilic acrylic (SC60B-OUV-MDR, Inc), two had silicone IOL (Allergan SI30NB). Two out of the three patients with opacified hydrophilic acrylic IOLs had diabetes mellitus. Three eyes with opacified acrylic IOL underwent IOL exchange with hydrophobic acrylic IOL. Two silicone IOL patients had no visually significant opacification and were managed conservatively. Conclusion IOL optic opacification in hydrophilic acrylic and silicone IOL may be due to defective material, manufacturing process, storage. How to cite this article Ram J, Gupta N, Chaudhary M, Sukhija JS, Gupta A, Kumar J. Late Opacification of Foldable Intraocular Lenses. J Postgrad Med Edu Res 2012;46(2):95-97.

In vitro comparison of glistening formation among hydrophobic acrylic intraocular lenses

2002 ◽  
Vol 28 (7) ◽  
pp. 1262-1268 ◽  
Author(s):  
Ninel Z. Gregori ◽  
Terrence S. Spencer ◽  
Nick Mamalis ◽  
Randall J. Olson
Keyword(s):  
Intraocular Lenses ◽  
Hydrophobic Acrylic ◽  
In Vitro Comparison

Scanning electron microscopic characteristics of manually loaded and preloaded foldable acrylic intraocular lenses

2018 ◽  
Vol 29 (1) ◽  
pp. 28-32
Author(s):  
Mahmoud Fathy Rateb ◽  
Zeiad Hasan Eldaly ◽  
Walid Saad Eldein Ibrahim ◽  
Ahmed Hasan Eldoghaimy
Keyword(s):  
Intraocular Lens ◽  
Visual Outcome ◽  
Intraocular Lenses ◽  
Common Finding ◽  
Control Group ◽  
Optical Surface ◽  
Electron Microscopic ◽  
The Impact ◽  
Hydrophobic Acrylic ◽  
Scanning Electron

Purpose: To compare surface alterations between preloaded and manually loaded intraocular lens. Methods: Scanning electron microscope was utilized to evaluate surface alteration and deposits in four different types of intraocular lenses: preloaded hydrophobic acrylic, preloaded hydrophilic acrylic, manually loaded hydrophobic acrylic, and manually loaded hydrophilic acrylic. Six lenses with different powers (+6 D, +22 D, and +29 D) were used from each category, to represent different thickness categories of the intraocular lenses. Results: In total, 30 intraocular lenses have been evaluated in this study: 4 from the control group (2 hydrophobic and 2 hydrophilic lenses) and 12 from the preloaded intraocular lens and manually loaded groups (6 hydrophilic and 6 hydrophobic lenses with different powers). Surface deposits were found in eight hydrophobic intraocular lenses compared to a single intraocular lens with scattered deposits on the optical surface of a hydrophilic intraocular lens. In manually loaded intraocular lens group, five hydrophobic and one hydrophilic intraocular lenses showed identifiable marks on the optical surface. In the preloaded intraocular lens group, three hydrophobic intraocular lenses showed identifiable marks on the optical surface and three hydrophobic intraocular lenses showed surface wrinkling. All hydrophilic intraocular lenses revealed no identifiable marks. Conclusion: Surface alterations and deposits are a common finding in both preloaded and manually loaded intraocular lenses. Water content of acrylic intraocular lenses is an important factor predisposing to these changes, and hydrophobic intraocular lenses are more vulnerable than hydrophilic lenses. The impact on the final visual outcome needs further studies.

scholarly journals Glistening formation in a new hydrophobic acrylic intraocular lens

2020 ◽  
Author(s):  
Timur M. Yildirim ◽  
Hui Fang ◽  
Sonja K. Schickhardt ◽  
Qiang Wang ◽  
Patrick R. Merz ◽  
...  
Keyword(s):  
Stress Test ◽  
In Vitro Study ◽  
Mean Value ◽  
Laboratory Method ◽  
Intraocular Lenses ◽  
Fort Worth ◽  
In Vitro Stress ◽  
Vision Care ◽  
Hydrophobic Acrylic

Abstract Background: The formation of fluid-filled microvacuoles, termed glistenings, is a common complication of intraocular lenses (IOLs) made from hydrophobic acrylate. Using our well-established in-vitro laboratory method, we evaluated a new IOL material’s resistance to glistening formation. Methods: An in-vitro stress test for glistening induction was performed on twenty samples of hydrophobic acrylic IOLs: ten of the new Eyecryl ASHFY600 (Biotech Vision Care, Ahmedabad, India) compared with ten samples of AcrySof IQ SN60WF (Alcon, Fort Worth, USA). The number of microvacuoles per square millimetre (MV/mm 2 ) was evaluated in five sections of each IOL. The results for each model were compared and rated on the Miyata Scale for grading glistening severity. Results: In all cases, glistening number was higher in the central section of the IOL optic than in the periphery. Mean number of MV/mm 2 was highest in the central part of the AcrySof IQ SN60WF, with 41.84 (±27.67) MVs/mm². The lowest number of glistenings was found in the five sections of the Eyecryl ASHFY600 with 0.52 (±0.24) MVs/mm². Mean value of the Eyecryl ASHFY600 IOL, using the Miyata Scale, was Zero. Conclusion: In this in-vitro laboratory study, the new hydrophobic acrylic IOL showed a high resistance to microvacuole formation. Results from this in-vitro study suggest that glistening numbers will be low in clinical use in the Eyecryl ASHFY600.

Interaction Between Silicone Oil and Silicone Intraocular Lenses: An In Vitro Study

1997 ◽  
Vol 28 (9) ◽  
pp. 776-779
Author(s):  
Peter Senn ◽  
Martin K Schmid ◽  
Isaak Schipper ◽  
Phillip Hendrickson
Keyword(s):  
Silicone Oil ◽  
In Vitro Study ◽  
Vitro Study ◽  
Intraocular Lenses

Methods of correction of aphakia in silicone tamponade of the vitreous cavity

2021 ◽  
pp. 68-72
Author(s):  
G.O. Karpov ◽  
◽  
R.R. Fayzrakhmanov ◽  
O.A. Pavlovsky ◽  
A.V. Sukhanova ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Comparative Analysis ◽  
Anterior Chamber ◽  
Intraocular Lens ◽  
Silicone Oil ◽  
Vitreous Cavity ◽  
Intraocular Lenses ◽  
Silicon Oil ◽  
Group 2 ◽  
Iol Fixation

The purpose of this study is to conduct a comparative analysis of the correction of aphakia by various models of intraocular lenses using silicon oil tamponade (SO) of the vitreous cavity. Materials and methods. The studies were conducted on 16 eyes of patients aged from 56 to 75 years (65.5±12 years) with aphakia and pathology of the vitreal cavity. The duration of the silicone tamponade was 2-3 months. Depending on the use of the type of IOL, all patients were divided into 2 groups. Results. When using an anterior chamber intraocular lens (IOL), the presence of ophthalmic hypertension was revealed in 75% of cases, which is 2.02 times higher than when using transcleral IOL fixation. In 37.5% of cases, the SO output to the anterior chamber is determined, in contrast to the group where IOL hemming was used. A higher percentage of SO migration to the anterior chamber of the eye in group 2 patients is due to a violation of the anatomy of the anterior chamber barrier and the vitreal cavity. Conclusion. Thus, in patients who underwent transcleral IOL fixation, visual acuity is 2.1 times higher than in patients who were implanted with an anterior chamber IOL. Transcleral fixation of the IOL can form the necessary barrier between the anterior and posterior chambers of the eye, and is also the closest IOL position to the physiological one. Key words: intraocular lens, silicone oil, transcleral fixation.

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