scholarly journals Design and Implementation of a Heating Treatment System for Vitiligo Skin Disease Based on Medical Ultrasound

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Juanjuan Gao ◽  
Fei Tian ◽  
Chong Lyu ◽  
Xianhua Qiao
Keyword(s):  
Skin Disease ◽  
Skin Diseases ◽  
High Energy ◽  
Ultrasound Treatment ◽  
Treatment System ◽  
Nonrigid Registration ◽  
Medical Ultrasound ◽  
Excitation Signal ◽  
Registration Algorithm ◽  
Heating Treatment

Vitiligo is relatively common clinically. It is an acquired and persistent skin and mucosal pigment depigmentation disease. As a noninvasive and nonradioactive treatment, high-energy ultrasound has been applied to skin diseases of vitiligo. Treatment achieved good clinical results. This article analyzes the structure of the original medical ultrasound system for vitiligo and finds the deficiencies and missing components of the system. On the basis of the original design scheme, a new structural scheme was designed, which solved the shortcomings of the original system and added missing parts. Subsequently, according to actual application requirements and specific component performance, the schematic design, including audio and video input, output and storage, DDR3, Ethernet, and the design of key circuits, such as power supply modules, are specifically introduced. Later, in the PCB design, the contents including stacking, layout, routing, and simulation of key signals were introduced in detail. The design includes a probe excitation signal generation module, excitation signal parameter control module, high voltage and temperature monitoring module, and corresponding power conversion module. This paper is mainly to develop a vitiligo skin disease heating treatment array system based on the principle of both cost and performance. This paper is based on the nonrigid registration algorithm of the FFD model and HPV interpolation and the nonrigid registration algorithm combining shape information and SIFT method. In the focused ultrasound treatment system, the image-guided positioning and monitoring functions are realized. Studies have shown that when the peak voltage of the transmitter circuit is 55 V, the sound power is 0.28 W. It can be seen that the transmitting circuit system designed in this article is a relatively stable and reliable system, which is suitable for the ultrasound treatment of vitiligo skin diseases.

Development of Dermatological Skin Disease Detection and Classification based on Wavelet and ANN

2018 ◽  
Vol 8 (5) ◽  
pp. 10
Author(s):  
Revati Kadu ◽  
U. A. Belorkar
Keyword(s):  
Neural Network ◽  
Artificial Neural Network ◽  
Skin Disease ◽  
Skin Diseases ◽  
Screening Method ◽  
Phase Detection ◽  
Statistical Measures ◽  
The World ◽  
Artificial Neural ◽  
Wavelet Techniques

One of the most common and augmenting health problems in the world are related to skin. The most  unpredictable and one of the most difficult entities to automatically detect and evaluate is the human skin disease because of complexities of texture, tone, presence of hair and other distinctive features. Many cases of skin diseases in the world have triggered a need to develop an effective automated screening method for detection and diagnosis of the area of disease. Therefore the objective of this work is to develop a new technique for automated detection and analysis of the skin disease images based on color and texture information for skin disease screening. In this paper, system is proposed which detects the skin diseases using Wavelet Techniques and Artificial Neural Network. This paper presents a wavelet-based texture analysis method for classification of five types of skin diseases. The method applies tree-structured wavelet transform on different color channels of red, green and blue dermoscopy images, and employs various statistical measures and ratios on wavelet coefficients. In all 99 unique features are extracted from the image. By using Artificial Neural Network, the system successfully detects different types of dermatological skin diseases. It consists of mainly three phases image processing, training phase, detection  and classification phase.

scholarly journals Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Cheng-Cheng Deng ◽  
Yong-Fei Hu ◽  
Ding-Heng Zhu ◽  
Qing Cheng ◽  
Jing-Jing Gu ◽  
...  
Keyword(s):  
Single Cell ◽  
Skin Disease ◽  
Skin Diseases ◽  
Rna Seq ◽  
Fibrotic Disease ◽  
Functional Studies ◽  
Fibrotic Diseases ◽  
Fibroblast Heterogeneity ◽  
Keloid Fibroblasts ◽  
Excessive Accumulation

AbstractFibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix. Fibroblasts are found to be heterogeneous in multiple fibrotic diseases, but fibroblast heterogeneity in fibrotic skin diseases is not well characterized. In this study, we explore fibroblast heterogeneity in keloid, a paradigm of fibrotic skin diseases, by using single-cell RNA-seq. Our results indicate that keloid fibroblasts can be divided into 4 subpopulations: secretory-papillary, secretory-reticular, mesenchymal and pro-inflammatory. Interestingly, the percentage of mesenchymal fibroblast subpopulation is significantly increased in keloid compared to normal scar. Functional studies indicate that mesenchymal fibroblasts are crucial for collagen overexpression in keloid. Increased mesenchymal fibroblast subpopulation is also found in another fibrotic skin disease, scleroderma, suggesting this is a broad mechanism for skin fibrosis. These findings will help us better understand skin fibrotic pathogenesis, and provide potential targets for fibrotic disease therapies.

scholarly journals Real-Time Lung Tumor Tracking Using a CUDA Enabled Nonrigid Registration Algorithm for MRI

2020 ◽  
Vol 8 ◽  
pp. 1-8
Author(s):  
Nazanin Tahmasebi ◽  
Pierre Boulanger ◽  
Jihyun Yun ◽  
Gino Fallone ◽  
Michelle Noga ◽  
...  
Keyword(s):  
Real Time ◽  
Lung Tumor ◽  
Nonrigid Registration ◽  
Registration Algorithm ◽  
Tumor Tracking

Approach to the Diagnosis of Skin Disease

2017 ◽  
Author(s):  
Robert T Brodell ◽  
Stephen E Helms ◽  
Lindsey B Dolohanty
Keyword(s):  
Key Words ◽  
Skin Disease ◽  
Skin Diseases ◽  
Suggested Approach ◽  
Diagnostic Skills ◽  
Diagnosis Errors

The diagnosis of skin disease is not something that changes radically year to year. In fact, for hundreds of years physicians have been assessing the skin to diagnose and treat skin diseases and  to “view” internal diseases. The latest edition of this review provides several updates that enhance our approach to the diagnosis of skin disease with active links to updated digital references and atlases. These will be valuable to students, residents, and physicians interested in improving their dermatologic diagnostic skills. A new algorithm highlights our suggested approach to cutaneous diagnoses. It is our hope that readers will begin to “think like dermatologists” as they digest the contents of this review.  Key words: Macule, papule, vesicle, bulla, plaque, excoriation, scale, ulceration, diagnosis, errors This review contains 13 figures, 5 tables, 17 references, and 7 additional readings.

The Importance of Skin Disease as Assessed by “Willingness-To-Pay”

2003 ◽  
Vol 7 (5) ◽  
pp. 369-371 ◽  
Author(s):  
Lauren Parks ◽  
Rajesh Balkrishnan ◽  
Line Hamel-Gariépy ◽  
Steven R. Feldman
Keyword(s):  
Willingness To Pay ◽  
Skin Disease ◽  
Skin Diseases ◽  
Medical Conditions ◽  
Monthly Basis ◽  
Related Quality ◽  
Health Related ◽  
Optimal Resource ◽  
The Impact

Background: To achieve optimal resource allocation in health care, it is necessary to value competing resource uses according to the benefit derived from those uses. Skin disease makes as great an impact as other serious medical conditions when assessed by effects on health-related quality of life. Objective: To confirm the high impact of skin disease by comparing patients' willingness to pay (WTP) to be cured or relieved from symptoms of skin and nonskin conditions. Methods: We searched the published literature on WTP to compare the impact of dermatologic conditions with the impact of other medical conditions. A total of 46 articles were identified of which 10 included information on willingness to pay for cure reported on a monthly basis. Results: WTP for skin diseases fell in the range of $125–260/month and was comparable or higher than all but one of the other identified conditions. Conclusion: Willingness to pay for relief from skin diseases is comparable to that for relief of other serious medical conditions. Skin diseases are associated with a significant adverse impact on patients' lives.

scholarly journals Skin disease prevalence study in schoolchildren in rural Côte d'Ivoire: Implications for integration of neglected skin diseases (skin NTDs)

2018 ◽  
Vol 12 (5) ◽  
pp. e0006489 ◽  
Author(s):  
Rie Roselyne Yotsu ◽  
Kouamé Kouadio ◽  
Bamba Vagamon ◽  
Konan N’guessan ◽  
Amari Jules Akpa ◽  
...  
Keyword(s):  
Cote D'ivoire ◽  
Skin Disease ◽  
Côte D’Ivoire ◽  
Skin Diseases ◽  
Disease Prevalence ◽  
Prevalence Study ◽  
Cote D’Ivoire ◽  
Côte D'ivoire

scholarly journals Stigmatisation and body image impairment in dermatological patients: protocol for an observational multicentre study in 16 European countries

BMJ Open ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. e024877 ◽  
Author(s):  
Florence J Dalgard ◽  
Anthony Bewley ◽  
Andrea W Evers ◽  
Uwe Gieler ◽  
Lars Lien ◽  
...  
Keyword(s):  
Body Image ◽  
Multicentre Study ◽  
Skin Disease ◽  
Skin Diseases ◽  
European Countries ◽  
Background Information ◽  
Psychosocial Burden ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
General Anxiety Disorder

IntroductionPatients with common skin diseases may have substantial psychosocial comorbidity and reduced quality of life. This study aims at exploring further the psychosocial burden of skin diseases by assessing stigmatisation and body image problems in a large sample of patients with skin disease across Europe.Methods and analysisThe study is an observational cross-sectional multicentre study across 16 European countries comparing stigmatisation and body image in patients with skin disease compared with controls. Consecutive patients will be recruited in outpatient clinics and will complete validated questionnaires prior to clinical examination by a dermatologist at each recruitment site. In addition to sociodemographic background information, the outcomes will be: mood disorders assessed by short versions of the Patient Health Questionnaire and the General Anxiety Disorder Assessment; general health assessed by the EuroQol-Visual Analogue Scale; stigmatisation experience assessed by the Perceived Stigmatisation Questionnaire; stress assessed by the Perceived Stress Scale and body image assessed by the Dysmorphic Concern Questionnaire. The main criteria for eligibility are to be 18 years old or more. The analysis will include comparison between patients and controls for the main outcomes using t-tests, analyses of covariance and multivariate logistic regression models adjusting for potential confounding factors.Ethics and disseminationThe study protocol is approved by the University of Giessen and by the local Ethical Committee in each recruitment centre. Informed consent will be given by each participant. The results of the study will be disseminated by publications in international peer-reviewed journals and presented at international conferences and general public conferences. Results will influence support intervention and management of patients with skin disease across Europe.Trial registration numberDRKS00012745; Pre-results.

scholarly journals Assessment of the quality of life of pediatric patients at a center of excellence in dermatology in southern Brazil

2012 ◽  
Vol 87 (5) ◽  
pp. 697-702 ◽  
Author(s):  
Magda Blessmann Weber ◽  
Daniel Lorenzini ◽  
Clarissa Prieto Herman Reinehr ◽  
Bárbara Lovato
Keyword(s):  
Quality Of Life ◽  
Skin Disease ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Pediatric Patients ◽  
Skin Diseases ◽  
Life Quality ◽  
Chronically Ill ◽  
Life Quality Index

BACKGROUND: Skin diseases cause negative impact on the emotional state, social relationships and daily activities, due to the stigma caused by the appearance of the lesions. OBJECTIVE: This study aimed to assess the quality of life of pediatric patients with skin diseases attending a dermatology service, compare the scores obtained among the dermatoses found in the sample and associate them to the variables, in addition to observing how the skin disease specifically affects quality of life. METHODS: Cross-sectional study, with patients between 5 and 16 years attending the Dermatology Service of the University of Health Sciences of Porto Alegre, Brazil, between July 2010 and February 2011. The data collection instruments were the Children's Dermatology Life Quality Index questionnaire and the AUEQI questionnaire. RESULTS: A total of 161 patients were interviewed, with mean age of 9,66 years. The main dermatoses were atopic dermatitis (29.8%), warts (13%) and molluscum contagiosum (7.5%). Chronic diseases (73.9%) were the most prevalent. The overall mean Children's Dermatology Life Quality Index score was 5.01 for chronic dermatoses and 2.07 for acute illnesses, indicating a compromised quality of life among chronically ill patients. The comparison between the scores obtained with the AUEQI scale and the Children's Dermatology Life Quality Index scores indicates that the overall quality of life is less affected than the specific quality of life related to the dermatosis. CONCLUSIONS: The data presented reinforce how important it is that the patients, their families and caregivers understand the symptoms, triggers and treatment of the skin disease in question. This information facilitates adherence to the treatment and justifies the conduct adopted by the dermatologist.

scholarly journals PSYCHOSOCIAL IMPACT OF COMMON SKIN DISORDERS – A REVIEW STUDY

2021 ◽  
Vol 9 (7) ◽  
pp. 1452-1456
Author(s):  
Manish Choudhari ◽  
Nikita Jamadari ◽  
Naresh Jain
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Skin Disease ◽  
Skin Diseases ◽  
Fungal Infections ◽  
Acne Vulgaris ◽  
Well Being ◽  
Psychosocial Impact ◽  
Common Skin

Objective - To increase awareness of the psychosocial impact of Kushtha, Visarpa, Mukhadushika, Sheetpitta, Udarda and Kotha in Ayurveda and Acne vulgaris, Urticaria, Various types of fungal infections, Atopic dermatitis, Psoriasis etc. in modern point of view. Quality Of Evidence - A literature review was based on a MEDLINE search (1966 to 2000). Selected articles from the dermatologic and psychiatric literature, as well as other relevant medical journals, were reviewed and used as the basis for discussion of how skin disease affects patients’ lives and of appropriate management. Message - Dermatologic problems hurt patients’ quality of life. skin disease can produce stress, anxiety, anger, depression, low self-esteem, embarrassment, and other psychological, personal, professional and social life problems that affect patients’ lives in ways comparable to arthritis or other disabling illnesses, as well as showing a bidirectional relationship between skin disease and psychological distress. This review focuses on the effects of five common skin diseases seen by family physicians- Acne, Urticaria, Various types of fungal infections, Atopic dermatitis and Psoriasis. Conclusion - How skin disease affects psychosocial well-being is un- derappreciated. Increased understanding of the psychiatric comorbidity associated with skin disease and a biopsy- chosocial approach to management will ultimately improve patients’ lives. Keywords: Skin disease, Psychosocial Impact, Quality of life.

Dermatology

2018 ◽  
Author(s):  
Gemma Simcox
Keyword(s):  
Quality Of Life ◽  
Skin Disease ◽  
Skin Diseases ◽  
Systemic Disease ◽  
Management Plan ◽  
Dermatological Examination ◽  
Common Skin ◽  
Life Threatening ◽  
The Uk

Skin disease has a serious impact on an individual’s quality of life. It is well recognized that conditions such as psoriasis may have a similar impact on a patient’s quality of life to chronic diseases such as diabetes, hypertension, and depression. Skin problems account for approximately 20% of all patient consultations in primary care in the UK. It is important that clinicians are able to diagnose common skin diseases such as acne, eczema, psoriasis, and cutaneous malignancies and initiate an appropriate management plan. This requires the ability to take a full history and conduct a complete examination. A complete dermatological examination involves examination of the entire skin, mucous membranes, hair, and nails. The description of cutaneous pathologies should include the location and distribution of lesions. The morphology of a lesion or each component of a generalized eruption should be noted. Other organ systems may also need to be examined. The questions in this chapter will test your knowledge of the skin problems that are frequently encountered in non-specialist clinical practice. Other more rare skin disorders are also covered, either because they are potentially life-threatening or because they are a sign of systemic disease. The questions are designed to improve your ability to recognize the morphology and distribution of cutaneous physical signs. Hopefully you will find these questions stimulating and an aid to improving your knowledge of skin disease.

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