scholarly journals A Review of Detection of Antibiotic Residues in Food by Surface-Enhanced Raman Spectroscopy

2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Jun-Fa Liang ◽  
Cheng Peng ◽  
Peiyu Li ◽  
Qiu-Xiong Ye ◽  
Yu Wang ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Liquid Chromatography ◽  
Surface Enhanced Raman Spectroscopy ◽  
Antibiotic Residues ◽  
Basic Principles ◽  
Promising Alternative ◽  
Residue Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Analytical Approaches

Antibiotics, as veterinary drugs, have made extremely important contributions to disease prevention and treatment in the animal breeding industry. However, the accumulation of antibiotics in animal food due to their overuse during animal feeding is a frequent occurrence, which in turn would cause serious harm to public health when they are consumed by humans. Antibiotic residues in food have become one of the central issues in global food safety. As a safety measure, rapid and effective analytical approaches for detecting these residues must be implemented to prevent contaminated products from reaching the consumers. Traditional analytical methods, such as liquid chromatography, liquid chromatography mass spectrometry, and capillary electrophoresis, involve time-consuming sample preparation and complicated operation and require expensive instrumentation. By comparison, surface-enhanced Raman spectroscopy (SERS) has excellent sensitivity and remarkably enhanced target recognition. Thus, SERS has become a promising alternative analytical method for detecting antibiotic residues, as it can provide an ultrasensitive fingerprint spectrum for the rapid and noninvasive detection of trace analytes. In this study, we comprehensively review the recent progress and advances that have been achieved in the use of SERS in antibiotic residue detection. We introduce and discuss the basic principles of SERS. We then present the prospects and challenges in the use of SERS in the detection of antibiotics in food. Finally, we summarize and discuss the current problems and future trends in the detection of antibiotics in food.

scholarly journals Untargeted Tumor Metabolomics with Liquid Chromatography–Surface‐Enhanced Raman Spectroscopy

2020 ◽  
Vol 59 (9) ◽  
pp. 3439-3443 ◽  
Author(s):  
Lifu Xiao ◽  
Chuanqi Wang ◽  
Chen Dai ◽  
Laurie E. Littlepage ◽  
Jun Li ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Liquid Chromatography ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Quantitative online sheath-flow surface enhanced Raman spectroscopy detection for liquid chromatography

The Analyst ◽  
2016 ◽  
Vol 141 (12) ◽  
pp. 3630-3635 ◽  
Author(s):  
Anh Nguyen ◽  
Zachary D. Schultz
Keyword(s):  
Raman Spectroscopy ◽  
Liquid Chromatography ◽  
Small Molecules ◽  
Surface Enhanced Raman Spectroscopy ◽  
Online Detection ◽  
Sheath Flow ◽  
Flow Surface ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Detection And Quantification

Sheath-flow surface-enhanced Raman spectroscopy (SERS) was used for online detection and quantification of small molecules separated by liquid chromatography.

scholarly journals Specific detection of Staphylococcus aureus infection and marker for Alzheimer disease by surface enhanced Raman spectroscopy using silver and gold nanoparticle-coated magnetic polystyrene beads

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Robert Prucek ◽  
Aleš Panáček ◽  
Žaneta Gajdová ◽  
Renata Večeřová ◽  
Libor Kvítek ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Raman Spectroscopy ◽  
Alzheimer Disease ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Magnetic Composites ◽  
Protein Marker ◽  
Promising Alternative ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

AbstractTargeted and effective therapy of diseases demands utilization of rapid methods of identification of the given markers. Surface enhanced Raman spectroscopy (SERS) in conjunction with streptavidin–biotin complex is a promising alternative to culture or PCR based methods used for such purposes. Many biotinylated antibodies are available on the market and so this system offers a powerful tool for many analytical applications. Here, we present a very fast and easy-to-use procedure for preparation of streptavidin coated magnetic polystyrene–Au (or Ag) nanocomposite particles as efficient substrate for surface SERS purposes. As a precursor for the preparation of SERS active and magnetically separable composite, commercially available streptavidin coated polystyrene (PS) microparticles with a magnetic core were utilized. These composites of PS particles with silver or gold nanoparticles were prepared by reducing Au(III) or Ag(I) ions using ascorbic acid or dopamine. The choice of the reducing agent influences the morphology and the size of the prepared Ag or Au particles (15–100 nm). The prepare composites were also characterized by HR-TEM images, mapping of elements and also magnetization measurements. The content of Au and Ag was determined by AAS analysis. The synthesized composites have a significantly lower density against magnetic composites based on iron oxides, which considerably decreases the tendency to sedimentation. The polystyrene shell on a magnetic iron oxide core also pronouncedly reduces the inclination to particle aggregation. Moreover, the preparation and purification of this SERS substrate takes only a few minutes. The PS composite with thorny Au particles with the size of approximately 100 nm prepared was utilized for specific and selective detection of Staphylococcus aureus infection in joint knee fluid (PJI) and tau protein (marker for Alzheimer disease).

Surface-Enhanced Raman Spectroscopy for Rapid Screening of Cinnamon Essential Oils

2020 ◽  
Vol 74 (11) ◽  
pp. 1341-1349
Author(s):  
Patrick Nelson ◽  
Perculiar Adimabua ◽  
Ankai Wang ◽  
Shengli Zou ◽  
Nilam C. Shah
Keyword(s):  
Raman Spectroscopy ◽  
Essential Oil ◽  
Essential Oils ◽  
Surface Enhanced Raman Spectroscopy ◽  
Basis Set ◽  
Rapid Screening ◽  
Promising Alternative ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Cinnamon Essential Oil

Cinnamon essential oil is used in food flavoring, food preservation, and for complementary medicine. The most common types of cinnamon used in essential oils are true cinnamon ( Cinnamomum verum) and cassia cinnamon ( Cinnamomum cassia). True cinnamon is commonly adulterated with cassia cinnamon because it is cheaper. However, cassia cinnamon contains higher concentrations of coumarin which has been shown to have adverse health effects. There is a need to develop simple, nondestructive, rapid screening methods for quality control and food authentication and to identify adulteration of cinnamon essential oil. Currently, the most common methods to screen for coumarin in cinnamon include high-performance liquid chromatography (HPLC) and gas chromatography (GC). However, these methods require time-consuming sample preparation and detection. Vibrational spectroscopy methods are emerging as a promising alternative for rapid, nondestructive screening for food safety applications. In this study, a rapid screening method has been developed to examine cinnamon essential oils using surface-enhanced Raman spectroscopy (SERS). The experimental spectra were compared to theoretical calculations using the DFT method BP86/6-311++G(d,p) basis set. The limit of detection of coumarin was determined to be 1 × 10–6 M or 1.46 mg/L using SERS with colloid paste substrates. Furthermore, 1:16 dilutions of cinnamaldehyde and 1:8 dilutions of eugenol were detected using SERS which can help determine if the cinnamon essential oil was made from bark or from leaves. Seven commercially available cinnamon essential oils were also analyzed and compared to reference solutions. SERS was able to discriminate between essential oils primarily composed of cinnamaldehyde and those composed of eugenol. Furthermore, the SERS method detected peaks that are attributed to coumarin in two of the commercially available samples. To date, this is the first time SERS has been used to rapidly screen cinnamon essential oils.

scholarly journals Facile Ag-Film Based Surface Enhanced Raman Spectroscopy Using DNA Molecular Switch for Ultra-Sensitive Mercury Ions Detection

Nanomaterials ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 596 ◽  
Author(s):  
Xiujie Liu ◽  
Mengmeng Liu ◽  
Yudong Lu ◽  
Changji Wu ◽  
Yunchao Xu ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Raman Spectroscopy ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Molecular Switch ◽  
Mercury Ions ◽  
Promising Alternative ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Ag Film

Heavy metal pollution has long been the focus of attention because of its serious threat to human health and the environment. Surface enhanced Raman spectroscopy (SERS) has shown great potential for metal detection owing to many advantages, including, requiring fewer samples, its minimal damage to specimen, and its high sensitivity. In this work, we proposed a simple and distinctive method, based on SERS, using facile silver film (Ag-film) combined with a DNA molecular switch, which allowed for the highly specific detection of heavy metal mercury ions (Hg2+). When in the presence of Hg2+ ions, the signals from Raman probes attach to single-stranded DNA, which will be dramatically enhanced due to the specific structural change of DNA strands—resulting from the interaction between Hg2+ ions and DNA bases. This SERS sensor could achieve an ultralow limit of detection (1.35 × 10−15 M) for Hg2+ detection. In addition, we applied this SERS sensor to detect Hg2+ in real blood samples. The results suggested that this SERS platform could be a promising alternative tool for Hg2+ detection in clinical, environmental, and food inspection.

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