scholarly journals Evaluation of the Extent of Primary Buccal Mucosal Graft Contracture in Augmentation Urethroplasty for Stricture Urethra: A Prospective Observational Study at a Tertiary Healthcare Centre

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
A. BhalaguruIyyan ◽  
P. Puvai Murugan ◽  
Chandranaath C. Alakhananda ◽  
B. M. Zeeshan Hameed
Keyword(s):  
Observational Study ◽  
Urethral Stricture ◽  
Buccal Mucosa ◽  
Prospective Observational Study ◽  
Successful Outcome ◽  
Urethral Stricture Disease ◽  
Buccal Mucosal Graft ◽  
Stricture Urethra ◽  
Tertiary Healthcare ◽  
Graft Removal

Introduction. Buccal mucosal graft (BMG) urethroplasty is considered as gold standard in the treatment of urethral stricture disease. The successful outcome after BMG urethroplasty varies between 66 and 99%. One of the possible causes for failure is BMG contracture. Primary BMG contracture rate is poorly understood and unreported. The present study aimed to evaluate the extent of contracture of buccal mucosa immediately after harvesting. Materials and Methods. This was a prospective observational study conducted in the Department of Urology at our institute between January 2016 and December 2019. All patients with urethral stricture disease undergoing BMG urethroplasty for the first time were enrolled in the study after obtaining informed consent. Demographic and patient clinical profile was noted. Based on the intraoperative urethral stricture size, the preharvest graft was marked on the buccal mucosa and the size was calculated. Postharvest unstretched size of the graft was measured immediately after graft removal from the oral cavity. Alteration in BMG size was analysed using paired t-test. Results. Forty-four patients were included in the study. Mean age of the patient was 53.6 years. Mean stricture length was 7.45 cm (range 4–12 cm). Mean pre- and postharvest BMG size was 8.3 × 1.5 cm and 7.6 × 1.3 cm, respectively. There was a 8.4% decrease in length and 9.5% decrease in width of the buccal mucosal graft. Conclusion. Primary buccal mucosal graft contracture is around 8.4% in length and 9.5% in width. It would be better to mark wider than necessary while harvesting buccal mucosa so that tension-free anastomosis is performed.

Buccal mucosal graft urethroplasty in male cats with traumatic complete urethral rupture

2022 ◽  
pp. 1-7
Author(s):  
Wanchart Yippaditr ◽  
Antja Watanangura ◽  
Disdanai Pencharee ◽  
Nobuo Sasaki
Keyword(s):  
Quality Of Life ◽  
Buccal Mucosa ◽  
Abdominal Cavity ◽  
Positive Contrast ◽  
Successful Outcome ◽  
Indwelling Catheter ◽  
Buccal Mucosal Graft ◽  
Graft Tissue ◽  
Urethral Rupture

Abstract OBJECTIVE To evaluate the feasibility of buccal mucosal graft urethroplasty for repairing complete urethral rupture in cats. ANIMALS 15 male domestic shorthair cats with traumatic complete urethral rupture. PROCEDURES In each cat, a section of buccal mucosa was harvested, sutured, and formed into a tubule by use of an 8F indwelling catheter as support. This tubular graft was connected to both ruptured ends of the urethra to renew the urinary passage. The catheter was left in place until the absence of leakage was confirmed by positive contrast retrograde urethrography. After spontaneous urination was confirmed, cats were discharged from the hospital. Six months later, urethrography was repeated and owners were asked to score their cats’ urinary function and quality of life. RESULTS 13 cats recovered well following surgery, with no complications in the oral cavity or surgical site and no signs of difficulty or discomfort when urinating. Urethrography 2 weeks and 6 months after surgery revealed no stricture or leakage in the abdominal cavity. The 2 remaining cats developed a urethral stricture and underwent second surgery with a successful outcome. At the 6-month follow-up, 14 cats had only mild urinary signs, and 1 cat had incontinency. Owners indicated they were delighted (n = 14) or pleased (1) with their cats’ quality of life. CLINICAL RELEVANCE Buccal mucosa was found to be a good source of graft tissue for performance of urethroplasty in male cats, yielding satisfactory outcomes with few postoperative complications. The described technique may be suitable for severe and complicated cases of urethral rupture in male cats.

Dorsal onlay buccal mucosal graft urethroplasty in female urethral stricture disease: a single-center experience

2013 ◽  
Vol 25 (4) ◽  
pp. 525-530 ◽  
Author(s):  
Apul Goel ◽  
Sagorika Paul ◽  
Divakar Dalela ◽  
Pushpalata Sankhwar ◽  
Satya Narayan Sankhwar ◽  
...  
Keyword(s):  
Urethral Stricture ◽  
Single Center ◽  
Urethral Stricture Disease ◽  
Single Center Experience ◽  
Buccal Mucosal Graft ◽  
Dorsal Onlay ◽  
Female Urethral Stricture

scholarly journals Outcome of One Stage Urethroplasty Using Buccal Mucosa for Long Segment Urethral Stricture

2020 ◽  
Vol 18 (2) ◽  
pp. 68-73
Author(s):  
Md Sirajul Islam ◽  
Md Faisal Islam ◽  
Anamur Rashid Choudhury ◽  
Sarforaj Ali Khan ◽  
Pranashis Saha
Keyword(s):  
Retrospective Study ◽  
Physical Examination ◽  
Urethral Stricture ◽  
Buccal Mucosa ◽  
Private Hospital ◽  
One Stage ◽  
Buccal Mucosal Graft ◽  
The Mean

Objective: To assess the outcome of one stage urethroplasty using buccal mucosa for long segment (>2cm) urethral stricture. Material & Method: This retrospective study was done in a private Hospital at Jessore from May, 2010 to October, 2012. Twenty nine patients were managed with one stage dorsal on lay buccal mucosal graft (BMG). Patients were followed up 3 monthly with history, physical examination and relevant investigations. The mean duration of follow up was 23 months. Result: The age of the patients ranged from18 years to 65 years with mean of 35years. The length of the stricture ranged from 2.5cm to 10 cm with mean length 5.5 cm. The mean duration operative period was 3.5 hours with range from 2 hours to 4.5 hours. Of the 29 patients, 15 patients (51.7%) had bulbar urethral stricture, 10 patients (34.5%) had penile urethral stricture and 4 patients (13.8) had pan urethralstricture. Success was defined as normal voiding without further procedure. The rate of recurrence noted in this study was 10.34%. Conclusion: One stage dorsal on lay BMG urethroplsaty is a reliable and satisfactory procedure for the management of long segment urethral stricture with minimum complication. Bangladesh Journal of Urology, Vol. 18, No. 2, July 2015 p.68-73

scholarly journals Evaluation of the incidence, risk factors, severity, and outcome of hydrocephalic fetuses in a tertiary healthcare center located in Northern India: a prospective observational study

2020 ◽  
Vol 9 (2) ◽  
pp. 595
Author(s):  
Aditi Jain Garg ◽  
Rehana Najam ◽  
Ritika Agarwal ◽  
Rajul Rastogi
Keyword(s):  
Risk Factors ◽  
Observational Study ◽  
Pregnant Women ◽  
Low Socioeconomic Status ◽  
Prospective Observational Study ◽  
Economic Status ◽  
Postnatal Period ◽  
Major Influence ◽  
Incidence Risk ◽  
Tertiary Healthcare

Background: Hydrocephalus is a heterogeneous disease marked by abnormal dilatation of the cerebral ventricles secondary to varying etiologies. This study was aimed to determine the incidence, risk factors, severity, and outcome of hydrocephalic fetuses presenting to a tertiary healthcare hospital located in northern India.Methods: In this prospective observational study, pregnant women visiting the obstetrics outpatient department of our hospital from 01 July 2017 to 31 June 2018 were screened for hydrocephalic fetuses via ultrasonography along with a detailed history, and a comprehensive battery of diagnostic investigations. They were followed up for a minimum period of two months after delivery/termination of pregnancy.Results: A total of 3627 pregnant women were screened, of which 10 had hydrocephalic fetuses in the observed time period. The incidence of hydrocephalus was determined to be 2.75 per 1000 live births. Low socio-economic status was identified as a major risk factor. 50% of the hydrocephalic fetuses were severely afflicted and were discontinued. The remaining 50% were successfully delivered and were managed via a ventriculo-peritoneal shunt or are under close observation in the postnatal period without any adverse outcome.Conclusions: The burden of hydrocephalus is considerably high in India, as compared to western countries. In rural settings, low socioeconomic status and lack of folic acid supplementation have a major influence in the etiopathogenesis of hydrocephalus. Management of hydrocephalus requires a multidisciplinary approach and is tailored according to the severity of the presentation. Severe cases of hydrocephalus and cases with associated anomalies have a poor prognosis.

scholarly journals Post COVID-19 sequelae: A prospective observational study from Northern India

2021 ◽  
Author(s):  
Shivdas Rajaram Naik ◽  
Manish Soneja ◽  
Soumendra Haldar ◽  
Netto George Mundadan ◽  
Prerna Garg ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Long Term Effects ◽  
Northern India ◽  
The North ◽  
Disturbed Sleep ◽  
Number Of Patients ◽  
Tertiary Healthcare ◽  
Severity Of The Disease

Background: Long COVID, or post-COVID-19 sequelae, is being seen in a growing number of patients reporting a constellation of symptoms, both pulmonary and extrapulmonary. Studies on COVID-19 recovered patients are scarce. Thus, there is a need to add granularity to our existing knowledge about the course and long-term effects of the infection. Aim: To describe the clinical details and risk factors of post-COVID sequelae in the North Indian population. Method: This prospective observational study was conducted at a tertiary healthcare centre in Northern India between October 2020 to February 2021. Patients aged >18 years with a confirmed COVID-19 disease were recruited after at least two weeks of diagnosis and interviewed for any post-COVID-19 symptoms. Results: Of 1234 patients recruited, who were followed up for a median duration of 91 days (IQR: 45-181 days), 495 (40.11%) patients had symptoms. In 223 (18.1%) patients, the symptoms resolved within four weeks, 150 (12.1%) patients had symptoms till twelve weeks, and 122 (9.9%) patients had symptoms beyond twelve weeks of diagnosis of COVID-19. Most common long COVID-19 symptoms included myalgia (10.9%), fatigue (5.5%), shortness of breath (6.1%), cough (2.1%), disturbed sleep (1.4%), mood disturbances (0.48%) and anxiety (0.6%). The major determinants of developing post-COVID-19 symptoms in the patients were hypothyroidism and the severity of the disease. Conclusion: Most often, patients complain of myalgias, fatigue, dyspnoea, cough and disturbed sleep. Patients who are hypothyroid or have recovered from moderate to severe COVID-19 are at higher risk of developing post-COVID sequelae. Therefore, a multidisciplinary approach is required to diagnose and manage COVID-19 recovered patients.

scholarly journals Clinical Predictors of Vibrator-Assisted Ejaculation following Spinal Cord Injury: A Prospective Observational Study

2021 ◽  
Author(s):  
Sivaram Alisseril ◽  
Navin B. Prakash ◽  
Bobeena Rachel Chandy ◽  
George Tharion
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Statistical Significance ◽  
Successful Outcome ◽  
Clinical Parameters ◽  
Clinical Predictors ◽  
Cord Injury ◽  
Assisted Ejaculation

Abstract Introduction Infertility in men with spinal cord injury (SCI) occurs due to combination of factors like erectile dysfunction, ejaculatory failure, and semen abnormalities. Penile vibratory stimulation (PVS) is a known method of treatment for anejaculation. Predicting successful outcome of PVS depends on several clinical factors, which assess the intactness of the neural arc pertaining to the spinal ejaculation pattern generator. This study reports the clinical predictors for successful candidacy for a PVS trial in males with SCI. Methods Twenty-three males with SCI, satisfying the inclusion criteria, were recruited in this prospective observational study. Participants underwent two trials of PVS with single high-amplitude vibrator. The clinical predictors recorded were neurological level, superficial abdominal reflex, cremasteric reflex, bulbocavernosus reflex, plantar reflex, ankle jerk, knee jerk, lower abdominal sensation, and hip flexor response. In addition, somatic responses during PVS were recorded and corelated. Participants who had successful ejaculation were “responders” and the others were termed as “nonresponders.” Binary logistic regression analysis of the clinical parameters was done to compare responders against nonresponders. Results Of the twenty-three males (mean age 33.2 ± 6.8 years) with paraplegia, all four persons with neurological level above T9 had successful ejaculation with PVS. Among all the clinical parameters in the study, presence of somatic responses showed statistical significance in predicting successful ejaculation (p-value = 0.02). Conclusion This study reports that in men with SCI, along with the level of injury, somatic responses and other clinical reflexes, should be considered concurrently to predict the outcome of vibrator assisted ejaculation.

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