Body Mass Index Showed No Impact on the Outcome of In Vitro Fertilization in Progestin-Primed Ovarian Stimulation Protocol

Purpose. To assess whether body mass index (BMI) affects the outcome of in vitro fertilization (IVF) in progestin-primed ovarian stimulation (PPOS) protocol. Methods. A retrospective study was conducted in the Reproductive Medicine Center, Renmin Hospital of Wuhan University, from June 2016 to June 2017. 636 infertile women who received PPOS protocol in IVF treatment were divided into three groups according to BMI. The data of basic characteristics, embryological outcomes, and cycle characteristics of controlled ovarian stimulation of different groups were collected and studied. Result(s). There was no significant difference in almost all the basic characteristics, embryological outcomes of controlled ovarian stimulation, and cycle characteristics of controlled ovarian stimulation among the three groups. There was a tendency that the duration of infertility was decreased with the increase of patients’ weight, although there was no significant difference ( P = 0.051 ). However, overweight patients had a higher fertilization rate than normal weight patients and underweight patients (70.3 vs. 67.7 vs. 66.8, P = 0.008 ), but two-pronuclei (2PN) fertilization rate and cleavage rate showed no significant difference among the three groups. Conclusion(s). BMI showed no impact on the outcome of the ovarian stimulation outcome in PPOS protocol. PPOS protocol may benefit overweight patients, for it attains the same effect with normal patients and requires no increase in gonadotropin (Gn) dose and Gn duration.

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Analysis of the applied technique of intravenous anesthesia for in vitro fertilization in obese and patients with normal body mass index

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh180227040v ◽

2019 ◽

Vol 147 (9-10) ◽

pp. 588-594

Author(s):

Nebojsa Videnovic ◽

Jovan Mladenovic ◽

Aleksandar Pavlovic ◽

Sladjana Trpkovic ◽

Milan Filipovic ◽

...

Keyword(s):

Body Mass Index ◽

In Vitro Fertilization ◽

Body Mass ◽

Muscle Relaxation ◽

Normal Body Mass Index ◽

Obese Patients ◽

Vitro Fertilization ◽

Normal Body ◽

Significant Difference

Introduction/Objective. In this study, the effects of applied anesthetic techniques were investigated in a retrospective analysis of obese patients and those with normal body mass index undergoing in vitro fertilization, using bispectral index as an indicator of anesthetic depth. Methods. In total 116 patients with normal body mass index were allocated to group N. Another 116 patients with body mass index > 30 kg/m2 were allocated to group O. Anesthetic protocol comprised midazolam for premedication, diclofenac for pre-emptive analgesia, propofol for induction and maintenance, alfentanil for analgesia, suxamethonium for muscle relaxation. We recorded and compared the monitored parameters using t-test and ?2 test. Results. Procedure duration and recovery time were significantly longer in O group (p < 0.01). There is a statistically significant difference (p = 0.000181) in the number of patients requiring mechanical ventilation after induction of anesthesia. Propofol consumption was significantly higher (p < 0.0001) in O group (2.7 ? 1.6 mg/kg) as compared to group N (2.1 ? 0.4 mg/kg). The incidence of postoperative nausea and vomiting was observed in six patients in N group (5.17%) and nine patients in O group (7.76%). Pain intensity was found higher in group O compared to group N (p < 0.0001). Assessment of patients? sedation using verbal scale reported no statistically significant difference between N and O groups (p = 0.2548). Conclusion. Induction and maintenance of anesthesia in obese patients results in increased consumption of propofol and the need for muscle relaxation. The statements of the patients who underwent the procedure under intravenous propofol and alfentanil serve as the best recommendation for clinical practice.

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GnRH agonist versus GnRH antagonist in ovarian stimulation: the influence of body mass index on in vitro fertilization outcome

Fertility and Sterility ◽

10.1016/j.fertnstert.2007.03.007 ◽

2008 ◽

Vol 89 (2) ◽

pp. 472-474 ◽

Cited By ~ 11

Author(s):

Jacob Rabinson ◽

Simion Meltcer ◽

Efraim Zohav ◽

Ofer Gemer ◽

Eyal Y. Anteby ◽

...

Keyword(s):

Body Mass Index ◽

In Vitro Fertilization ◽

Body Mass ◽

Gnrh Agonist ◽

Ovarian Stimulation ◽

Gnrh Antagonist ◽

Vitro Fertilization

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Comprehensive analysis of body mass index effects on in vitro fertilization outcomes

10.26226/morressier.573c1512d462b80296c98821 ◽

2016 ◽

Author(s):

Laura Privitera

Keyword(s):

Body Mass Index ◽

In Vitro Fertilization ◽

Body Mass ◽

Comprehensive Analysis ◽

Vitro Fertilization

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Faculty Opinions recommendation of Clomiphene citrate in combination with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilization.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717964658.793468288 ◽

2013 ◽

Author(s):

Fatma F Verit

Keyword(s):

In Vitro Fertilization ◽

Ovarian Stimulation ◽

Clomiphene Citrate ◽

Controlled Ovarian Stimulation ◽

Vitro Fertilization

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Body Mass Index, Follicle-Stimulating Hormone and their Predictive Value in vitro Fertilization

Revista de Chimie ◽

10.37358/rc.18.7.6428 ◽

2018 ◽

Vol 69 (7) ◽

pp. 1842-1845

Author(s):

Lavinia Stelea ◽

Izabella Petre ◽

Marius Craina ◽

Brigitha Vlaicu ◽

Alina Sisu ◽

...

Keyword(s):

Body Mass Index ◽

Risk Factor ◽

In Vitro Fertilization ◽

Body Mass ◽

Predictive Value ◽

Follicle Stimulating Hormone ◽

Vitro Fertilization ◽

Weight Problems ◽

Fertility Disorder

The aim of this study was to determine if body mass can be considered a risk factor for infertility, and if we can find any correlations between the age values and the FSH and estradiol values, and between the BMI values and the FSH and estradiol values. Our whole sample contains 100 patients splinted in two groups (pregnant patients N1=57 subjects, 57%, and not � pregnant patients N1=43 subjects,43%). In the first part we conducted our analysis on the whole group and after that we focused the analysis on the two groups and we made some comparisons between the groups. We obtained a medium, extremely significant correlation in all scenarios between the age and the FSH values. This is the best association from all the cases which we tested. In all twelve cases we have a positive correlation (r ] 0). As well, we obtained that a BMI value higher than 25can be considered a risk factor for obtaining a pregnancy (p[0.05, RR ] 1, OR]1) . Our study shows that women who have weight problems have much less chances of conceiving a baby, even if they ovulate normally. The risk of infertility increases proportionally to the extra pounds. Irregular ovulation in women is the most common fertility disorder due to obesity disease.

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