scholarly journals Local treatment of a pediatric osteosarcoma model with a 4-1BBL armed oncolytic adenovirus results in an antitumor effect and leads to immune memory

2021 ◽  
pp. molcanther.MCT-21-0565-A.2021
Author(s):  
Naiara Martínez-Vélez ◽  
Virginia Laspidea ◽  
Marta Zalacain ◽  
Sara Labiano ◽  
Marc Garcia-Moure ◽  
...  
Keyword(s):  
Antitumor Effect ◽  
Local Treatment ◽  
Oncolytic Adenovirus ◽  
Immune Memory ◽  
Pediatric Osteosarcoma

An Oncolytic Adenovirus Expressing SNORD44 and GAS5 Exhibits Antitumor Effect in Colorectal Cancer Cells

2017 ◽  
Vol 28 (8) ◽  
pp. 690-700 ◽  
Author(s):  
Sujing Yuan ◽  
Yu Wu ◽  
Yigang Wang ◽  
Jianhua Chen ◽  
Liang Chu
Keyword(s):  
Colorectal Cancer ◽  
Cancer Cells ◽  
Antitumor Effect ◽  
Oncolytic Adenovirus ◽  
Colorectal Cancer Cells

scholarly journals The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma

2015 ◽  
Vol 22 (9) ◽  
pp. 2217-2225 ◽  
Author(s):  
Naiara Martínez-Vélez ◽  
Enric Xipell ◽  
Beatriz Vera ◽  
Arlet Acanda de la Rocha ◽  
Marta Zalacain ◽  
...  
Keyword(s):  
Therapeutic Approach ◽  
Oncolytic Adenovirus ◽  
Pediatric Osteosarcoma

scholarly journals Oncolytic adenovirus-mediated shRNA against Apollon inhibits tumor cell growth and enhances antitumor effect of 5-fluorouracil

Gene Therapy ◽  
2008 ◽  
Vol 15 (7) ◽  
pp. 484-494 ◽  
Author(s):  
L Chu ◽  
J Gu ◽  
L Sun ◽  
Q Qian ◽  
C Qian ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Antitumor Effect ◽  
Oncolytic Adenovirus ◽  
Tumor Cell Growth

scholarly journals Prostate Cancer-Specific of DD3-driven oncolytic virus-harboring mK5 gene

Open Medicine ◽  
2018 ◽  
Vol 14 (1) ◽  
pp. 1-9
Author(s):  
Jiali Hao ◽  
Wenjie Xie ◽  
Hui Li ◽  
Runsheng Li
Keyword(s):  
Prostate Cancer ◽  
Cell Proliferation ◽  
Differential Display ◽  
Tumor Angiogenesis ◽  
Oncolytic Virus ◽  
Antitumor Effect ◽  
Oncolytic Adenovirus ◽  
Male Population ◽  
Human Plasminogen ◽  
Inhibit Cell Proliferation

AbstractProstate cancer (PCa) is the second most diagnosed cancer in Western male population. In this study, we insert mK5 (the mutational kringle5 of human plasminogen) into a DD3-promoted (differential display code 3) oncolytic adenovirus to construct OncoAd.mK5.DD3. E1A.dE1B, briefly, OAd.DD3.mK5. DD3 is one of the most prostate cancer specific promoters which can transcriptionally control adenoviral replication. mK5 has been proved to be able to inhibit the tumor angiogenesis and inhibit cell proliferation. Our results suggested that targeting PCa with OAd.DD3.mK5 elicited strong antitumor effect.

scholarly journals E2F Promoter-Regulated Oncolytic Adenovirus with p16 Gene Induces Cell Apoptosis and Exerts Antitumor Effect on Gastric Cancer

2009 ◽  
Vol 54 (7) ◽  
pp. 1606-1606 ◽  
Author(s):  
Juming Ma ◽  
Xiaoping He ◽  
Weiguo Wang ◽  
Yao Huang ◽  
Lin Chen ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cell Apoptosis ◽  
Antitumor Effect ◽  
Oncolytic Adenovirus ◽  
P16 Gene
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