Abstract 900: Mental health disorders among ovarian cancer survivors in a population-based cohort

Author(s):  
Siqi Hu ◽  
David Baraghoshi ◽  
Esther Chang ◽  
Kerry Rowe ◽  
John Snyder ◽  
...  
2019 ◽  
Vol 42 (4) ◽  
pp. 355-362 ◽  
Author(s):  
Shane Lloyd ◽  
David Baraghoshi ◽  
Randa Tao ◽  
Ignacio Garrido-Laguna ◽  
Glynn W. Gilcrease ◽  
...  

Author(s):  
Jan Sebastian Novotny ◽  
Juan Pablo Gonzalez Rivas ◽  
Sarka Kunzova ◽  
Maria Skladana ◽  
Anna Pospisilova ◽  
...  

Objective: To date, cross-sectional surveys reported frequency and distribution of mental health disorders on convenience samples impacted by Covid-19. Longitudinal assessment of mental health during Covid-19 in a representative population-based sample, however, is currently largely missing. The aim of this study was to investigate changes in perceived stress levels and depressive symptoms measured before and during Covid-19 pandemic in a representative population-based sample. Methods: Baseline data on stress levels and depressive symptoms from a well-established population-based sample were compared with those obtained from self-administered e-questionnaires distributed during Covid-19 pandemic. A total of 715 participants completed e-questionnaires. Wilcoxon signed-rank test was used to test repeated-measure differences, while between-group differences were analysed using Mann-Whitney and the Kruskal-Wallis tests. Results: Perceived stress levels and depressive symptoms increased 1.4 and 5.5 times, respectively, during the Covid-19 pandemic compared to the time prior Covid-19. Changes in stress and depressive symptoms were most significant in females and did not depend on whether one quarantined alone or with others. Feeling of loneliness during Covid-19 pandemic had the greatest impact on increased stress levels and depressive symptoms. Conclusions: This population-based longitudinal study showed that Covid-19 related measures had significant impact on mental health in a general population with the feeling of loneliness identified as the biggest risk factor. This impact indicates the need of timely and tailored treatment of mental health disorders and integration of preventive mental health measures into global public health policies to protect mental health during future pandemics.


SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A349-A350
Author(s):  
E Bourchtein ◽  
S L Calhoun ◽  
K Puzino ◽  
A McQuillen ◽  
F He ◽  
...  

Abstract Introduction Mental health disorders (MHD) are a known risk factor for the development of insomnia symptoms in youth. However, a number of children with MHD do not go on to develop insomnia symptoms later on in life. Little is known about possible childhood factors that exacerbate or mitigate the risk of developing adolescent insomnia symptoms (AIS) among children with MHD. The present study examined, in an at-risk group of children with MHD, the behavioral profiles associated with the development of AIS. Methods The Penn State Child Cohort is a random, population-based sample of 700 children (5-12y), of whom 421 were followed up as adolescents (12-23y). Absence of childhood insomnia symptoms was ascertained by parent-reports (n=312), while presence of AIS in this subgroup was ascertained by self-reports (n=97). Presence of MHD was ascertained based on the clinical history and physical exam at baseline (n=52). The Pediatric Behavior Scale (PBS) assessed multiple parent-reported behavioral domains. Results Children with MHD at baseline had greater levels of difficulty across a variety of internalizing (e.g., anxiety, depression) and externalizing (e.g., impulsivity, hyperactivity) behavioral domains than those without MHD, regardless of whether they developed AIS. However, children with MHD who went on to develop AIS had significantly greater levels of aggressive (p<0.001) and oppositional (p=0.006) behaviors relative to children with MHD who did not develop AIS. In fact, these latter children did not differ from peers without any history of MHD or AIS on levels of aggressive (p=0.820) or oppositional (p=0.436) behaviors. Conclusion Children with MHD who present with normative aggressive and oppositional behaviors are less likely to develop AIS. Healthcare providers should consider providing preventative sleep interventions to youth with MHD who are exhibiting comorbid externalizing behaviors. Support National Institutes of Health (R01HL136587, R01HL97165, R01HL63772, UL1TR000127)


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