Ischemic Stroke in Young Asian Women: Risk Factors, Subtypes and Outcome

2010 ◽  
Vol 30 (4) ◽  
pp. 418-422 ◽  
Author(s):  
Mohammad Wasay ◽  
Subhash Kaul ◽  
Bindu Menon ◽  
Narayanaswamy Venketasubramanian ◽  
Padma Gunaratne ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Asian Women ◽  
Stroke In Young

Abstract WMP53: Traditional Vascular Risk Factors Account for Different Proportions of Ischemic Stroke Within Different Gender and Race Groups

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Elizabeth M Aradine ◽  
Yan Hou ◽  
Kathleen A Ryan ◽  
Prachi Mehndiratta ◽  
Michael S Phipps ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischemic Stroke ◽  
Black Men ◽  
White Men ◽  
Vascular Risk Factors ◽  
Vascular Risk ◽  
Odds Ratios ◽  
Stroke In Young Adults ◽  
Stroke In Young

Introduction: Few studies have compared the proportion of ischemic strokes attributable to traditional vascular risk factors (population-attributable risk percent or PAR%) between genders and races. The PAR% is a function of the population prevalence and strength of association of a risk factor. Methods: A population-based case-control study of ischemic stroke in young adults ages 18-49 in the Baltimore-Washington region was used to study the prevalence, odds ratios, and PAR% of hypertension, diabetes, and smoking among blacks and whites. Logistic regression was used to calculate age-adjusted odds ratios. All analyses were stratified by gender. Results: There were 1044 cases and 1099 controls. Of the cases, 47% were black, 54% were women. Roughly a quarter to a third of all strokes in women were attributable to smoking. Due to the higher prevalence of hypertension and a higher odds ratio for hypertension in black men (OR 3.9, 95% CI 2.6-5.9) compared to white men (OR 1.8, 95% CI 1.3-2.6), there was a much higher PAR% for hypertension among black men than white men. See Table 1 for prevalence and Table 2 for PAR% stratified by gender and race. Conclusion: Traditional vascular risk factors have the potential to explain a high proportion of ischemic stroke in young adults. The high proportion of strokes in women attributable to smoking underscores the need for targeted smoking cessation interventions in this population. Diabetes and, especially, hypertension are important contributors to the excess population burden of ischemic stroke among blacks. These findings support the value of early screening and treatment for hypertension in young blacks.

Risk factors and prognosis of ischemic stroke in young patients in Uzbekistan

2011 ◽  
Vol 5 ◽  
pp. 16-22
Author(s):  
Dilshod Sagatov ◽  
Khurshidakhon Rasulova ◽  
Yakutkhon Madjidova
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Young Patients ◽  
Stroke In Young

scholarly journals Distribution of risk factors of ischemic stroke in Chinese young adults and its correlation with prognosis

BMC Neurology ◽  
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Xiaoke Wu ◽  
Yutian Zou ◽  
Shoujiang You ◽  
Yanlin Zhang
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Young People ◽  
Poor Prognosis ◽  
Sinus Thrombosis ◽  
Large Vessel Occlusion ◽  
Vessel Occlusion ◽  
Definition Of ◽  
Toast Classification ◽  
Stroke In Young

Abstract Background The risk factors for ischemic stroke in young people are complex, varied and closely related to prognosis. This study aims to analyze the risk factors for ischemic stroke in Chinese young people and to explore the main factors influencing the prognosis. Method A total of 444 patients aged 16 to 45 years with ischemic stroke admitted to Suzhou tertiary hospital from 2011 to 2019 were retrospectively analyzed. Risk factors were identified according to the IPSS definition of pediatric stroke and the TOAST classification. All patients were followed up, and the modified Rankin score was used to evaluate the prognosis. Logistic regression analysis was used to explore the influencing factors of poor prognosis. Results Among the patients, 12 risk factors were found according to the IPSS definition of pediatric stroke, and 5 types of stroke were found according to the TOAST classification. A total of 299 patients had a good prognosis. Anemia, venous sinus thrombosis, isolated large-vessel occlusion, and high baseline NIHSS score were significant risk factors. Conclusion The IPSS definition enables patients to be classified on the basis of more risk factors than other classification methods. The prognosis of ischemic stroke in young people is generally good in the 5 years following the event. Anemia, venous sinus thrombosis, isolated large-vessel occlusion and high baseline NIHSS score were associated with poor prognosis.

scholarly journals Accident vasculaire cérébral chez les sujets jeunes : à propos d'une jeune femme

2020 ◽  
Vol 7 (1) ◽  
pp. 59-60
Author(s):  
Amrous Amine ◽  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Clinical Case ◽  
Cerebral Arteries ◽  
Epidemiological Data ◽  
Common Type ◽  
Young Subjects ◽  
Embolic Risk ◽  
Stroke In Young

According to epidemiological data, stroke’s incidence is clearly growing, especially in young people under 45. Ischemic stroke is the most common type (80%). Many risk factors have been identified, including hypertension, tobacco, dyslipidemia, diabetes, alcohol, and oestroprogestogenic contraceptive pill. The main mechanisms are atheroma of large arterial trunks, occlusion of small cerebral arteries unrelated to atherosclerosis, and cardio-embolic causes. The aim of our study is to present a clinical case of ischemic stroke in young subjects caused by heart disease at high embolic risk.

Risk Factors, Etiology, and Clinical Outcome of Ischemic Stroke in Young Adults Admitted in a Tertiary Care Hospital in India

2019 ◽  
Vol 2 (1) ◽  
pp. 32-39
Author(s):  
Madhavi Karri ◽  
Balakrishnan Ramasamy
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischemic Stroke ◽  
Clinical Outcome ◽  
Tertiary Care ◽  
Care Hospital ◽  
Diagnostic Challenge ◽  
Stroke Treatment ◽  
Stroke In Young Adults ◽  
Stroke In Young

Background: Ischemic stroke in young adults is becoming a rising concern with the increase in vulnerability to traditional risk factors and changing lifestyles. Aim: An overview of risk factors, classification, and clinical outcome of ischemic stroke in young adults (19 to 45 years) has been presented. Methods: Data fulfilling the study criteria from the stroke registry between June 2014 and June 2017 were collected, and a detailed proforma was taken that included history, clinical examination, and routine investigations. Selective investigations such as prothrombotic workup and 24-hour Holter monitoring were performed. Stroke was subclassified using the Trial of Org 10172 in Acute Stroke Treatment criteria. National Institute of Health Stroke Scale (NIHSS) scores at baseline and the modified Rankin score (mRS) scoring after 3 months of patients’ admission were calculated. Results: Out of 223 identified cases of ischemic stroke in young adults, 186 (83.4%) were taken for analysis, constituting 7.3% of the total stroke population of 3,059. Among the cases taken for analysis, 137 were males and 49 were females. A total of 150 patients were among the age group of 36 to 45 years. Dyslipidemia, smoking, and alcohol consumption were prevalent in the study group. Atherosclerotic strokes were predominant in the study population. NIHSS scores at admission had a significant impact on mRS scores after 3 months. In this study, only 4% reported the recurrence of stroke, whereas mortality was about 0.02%. Conclusions: Workup required for ischemic stroke in young adults has always been a diagnostic challenge for physicians who treat the stroke patients, and this must be optimized in all health care centers. Despite extensive workup, 23.66% participants were found to be cryptogenic in this study. The clinical outcome was good in this study with less mortality observed.

Risk factors, etiology, and outcome of ischemic stroke in young adults: A Japanese multicenter prospective study

2020 ◽  
Vol 417 ◽  
pp. 117068
Author(s):  
Yu Kono ◽  
Yuka Terasawa ◽  
Kenichiro Sakai ◽  
Yasuyuki Iguchi ◽  
Yasuhiro Nishiyama ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischemic Stroke ◽  
Prospective Study ◽  
Stroke In Young Adults ◽  
Multicenter Prospective Study ◽  
Stroke In Young

Stroke in Young Women

2011 ◽  
Vol 38 (3) ◽  
pp. 404-410 ◽  
Author(s):  
Meredith Salisbury ◽  
Gerald Pfeffer ◽  
Samuel Yip
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Secondary Prevention ◽  
Migraine With Aura ◽  
Young Women ◽  
Age Group ◽  
Primary And Secondary Prevention ◽  
Vascular Disorders ◽  
Autoimmune Conditions ◽  
Stroke In Young

In women ages 15-45 years, an additional set of risk factors are important in the pathogenesis of ischemic stroke. Some of these pertain strictly to women, and relate to exogenous hormones and pregnancy. Various other conditions are more common in women, which include migraine with aura, selected vascular disorders and autoimmune conditions. These differences do have implications for management in both the primary and secondary prevention of stroke in this age group.

scholarly journals Risk factors including prothrombotic work up in young ischemic stroke Indian patients

2020 ◽  
Vol 7 (4) ◽  
pp. 547
Author(s):  
Amit Sreen ◽  
Prafull Sharma ◽  
Vivek Guleria ◽  
Niket Verma
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Protein C ◽  
Tertiary Care ◽  
Protein S ◽  
Protein C Deficiency ◽  
Factor V Leiden Mutation ◽  
Major Health Problem ◽  
Work Up ◽  
Stroke In Young

Background: Stroke in young poses a major health problem. Various Indian studies have shown the incidence of stroke to be 10-15%. Cerebral venous thrombosis and rheumatic heart disease are the leading causes of stroke in the young in India. Thrombophilic factors have been implicated in 4-8% of the young strokes worldwide. Protein C deficiency is the most common thrombophilia marker followed by a deficiency of protein S, Factor V Leiden mutation, and antithrombin (AT) deficiency. Aims and objectives was the study of stroke in young is important for various reasons. The etiology and risk factors are more diverse and different as compared to the elderly. Therefore, these may indicate separate therapeutic approaches. The aim is to study the profile of ischemic stroke cases among the young.Methods: The study was carried out at a tertiary care defence hospital between December 2018 to December 2019. All cases of fresh ischemic stroke who were more than 15 and less than 45 years of age were included. Following clinical evaluation, patients underwent complete haemogram, blood sugar levels, lipid profile and other metabolic parameters. All patients were subjected to chest radiography, 12 lead ECG, and 2D echocardiography, Non-contrast CT head and MRI brain. Prothrombotic work up was also done.Results: A total of 41 patients (12.69%) presented with ischemic stroke before 45 years of age. Out of these 10 (24%) were females and 31 (76%) were male. None of the women smoked or consumed alcohol. Among the males, 19 (47%) smoked more than 10 cigarettes or bidis per day and 9 (22%) were moderate-to-heavy drinkers of alcohol. Hypertension was present in 7 (18%) and diabetes mellitus in 3 (7%) patients. Serum cholesterol was elevated in 7 (18%) patients and triglycerides in 17 (42%). Protein S deficiency was found in 28.8% patients, while protein C deficiency was detected in 21% patients and antithrombin III deficiency in 12% patients.Conclusions: Although traditional risk factors, such as hypertension, diabetes, and smoking, are associated with stroke in both elderly and young, this study shows that other modifiable risk factors such as alcohol consumption were also prevalent. The most common etiological cause was found to be venous infarction followed by cardio embolic cause. Deficiency of Protein S was the most common prothrombotic defect followed by deficiency of Protein C.

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