Endocranial Casts of Pre-Mammalian Therapsids Reveal an Unexpected Neurological Diversity at the Deep Evolutionary Root of Mammals

2017 ◽  
Vol 90 (4) ◽  
pp. 311-333 ◽  
Author(s):  
Julien Benoit ◽  
Vincent Fernandez ◽  
Paul R. Manger ◽  
Bruce S. Rubidge

The origin and evolution of the mammalian brain has long been the focus of scientific enquiry. Conversely, little research has focused on the palaeoneurology of the stem group of Mammaliaformes, the Permian and Triassic non-mammaliaform Therapsida (NMT). This is because the majority of the NMT have a non-ossified braincase, making the study of their endocranial cast (sometimes called the “fossil brain”) problematic. Thus, descriptions of the morphology and size of NMT endocranial casts have been based largely on approximations rather than reliable determination. Accordingly, here we use micro-CT scans of the skulls of 1 Dinocephalia and 3 Biarmosuchia, which are NMT with a fully ossified braincase and thus a complete endocast. For the first time, our work enables the accurate determination of endocranial shape and size in NMT. This study suggests that NMT brain size falls in the upper range of the reptilian and amphibian variation. Brain size in the dicynodont Kawingasaurus is equivalent to that of early Mammaliaformes, whereas the Dinocephalia show evidence of a secondary reduction of brain size. In addition, unlike other NMT in which the endocast has a tubular shape and its parts are arranged in a linear manner, the biarmosuchian endocast is strongly flexed at the level of the midbrain, creating a near right angle between the fore- and hindbrain. These data highlight an unexpected diversity of endocranial size and morphology in NMT, features that are usually considered conservative in this group.

2019 ◽  
Vol 12 (10) ◽  
pp. 5503-5517 ◽  
Author(s):  
Pascal Hedelt ◽  
Dmitry S. Efremenko ◽  
Diego G. Loyola ◽  
Robert Spurr ◽  
Lieven Clarisse

Abstract. The accurate determination of the location, height, and loading of sulfur dioxide (SO2) plumes emitted by volcanic eruptions is essential for aviation safety. The SO2 layer height is also one of the most critical parameters with respect to determining the impact on the climate. Retrievals of SO2 plume height have been carried out using satellite UV backscatter measurements, but, until now, such algorithms are very time-consuming. We have developed an extremely fast yet accurate SO2 layer height retrieval using the Full-Physics Inverse Learning Machine (FP_ILM) algorithm. This is the first time the algorithm has been applied to measurements from the TROPOMI instrument onboard the Sentinel-5 Precursor platform. In this paper, we demonstrate the ability of the FP_ILM algorithm to retrieve SO2 plume layer heights in near-real-time applications with an accuracy of better than 2 km for SO2 total columns larger than 20 DU. We present SO2 layer height results for the volcanic eruptions of Sinabung in February 2018, Sierra Negra in June 2018, and Raikoke in June 2019, observed by TROPOMI.


2003 ◽  
Vol 30 (4) ◽  
pp. 411 ◽  
Author(s):  
Paul G. McDonald

The accurate determination of nestling age and sex is an important tool for studies that examine life-history traits and ecological interactions. Despite the widespread distribution of the brown falcon, Falco berigora, in Australia, morphological criteria for sexing nestlings of this species have yet to be published and nestling development has not been intensively studied. While an ageing formula for the species exists, the small sample from which it was derived precluded appropriate statistical assessment of independence problems and other potentially confounding variables such as hatch order and sex. This study used a larger sample of free-living nestlings to account for these factors and found the most reliable measure for ageing nestlings to be wing length. Wing length increased linearly with chick age, independent of seven other potentially confounding factors examined. Ageing formulae based on wing length before and after remiges emerge are presented. In addition, an accurate test for determining nestling sex at banding age, based on tarsus width, is proposed. Nestling chronology of this species is also described in detail for the first time. Nestling development was similar to that described for other Falconiformes; however, the chronology of nestling development was too variable to be useful in assigning chick age. Despite this, within 6 days of the eldest chick hatching the relative brightness of down and the degree to which chicks' eyes had opened were useful in assigning hatch order amongst nestlings with similar wing lengths.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Carlos Sánchez-Hernández ◽  
Lionel Gourichon ◽  
Eric Pubert ◽  
William Rendu ◽  
Ramón Montes ◽  
...  

Abstract We propose for the first time the use of the combination of two high-resolution techniques, dental wear (meso- and microwear) and dental cementum analyses, to gain a better understanding of Neanderthal subsistence strategies and occupational patterns. Dental wear analysis provides information not only on ungulate palaeodiet and palaeoenvironments but also on hunting time and seasons. Dental cementum analysis allows the accurate determination of the age and season at death of a prey. Our study has focused on the Cantabrian region and has applied both methods to investigate the Mousterian faunal assemblages in Covalejos Cave. Identification of the ungulate palaeodiet reveals information on the environmental conditions of the studied region. Moreover, it may facilitate observation on the evolution of both palaeodiet and palaeoenvironment throughout the site sequence. Results show a general stability in the palaeoenvironmental conditions and in the ungulate palaeodiet throughout the Mousterian sequence; this finding may be attributed to the role of the area as a climate refuge, and slight differences in levels 8, 7 and 4 suggest long- or short-term but repeated Neanderthal occupations at different seasons in the annual cycle.


2020 ◽  
Vol 12 (39) ◽  
pp. 4749-4758 ◽  
Author(s):  
M. Haššo ◽  
O. Sarakhman ◽  
D. M. Stanković ◽  
Ĺ. Švorc

For the first time, we propose a novel modification-free voltammetric platform for simple, fast and reliable quantification of the sport performance-enhancing stimulant synephrine on the screen-printed boron-doped diamond electrochemical sensor.


Author(s):  
Mohamed Sayed Abdel El-Kader

Polarized and depolarized interaction-induced light scattering spectra at room temperature (294.5±1) K have been used for deriving the empirical multiparameter Morse–Morse–Morse–spline–van der Waals interatomic potential. These new data of scattering are accurate enough to permit for the first time a reliable determination of the interatomic potential of the gaseous helium as a function of the interatomic separation. The potential parameters describing the location and depth of the attractive well are given by ε = 11.2±0.015 K,


2007 ◽  
Vol 10 (S1) ◽  
pp. 1-2
Author(s):  
Robert Derom

AbstractThe East Flanders Prospective Twin Survey, started in 1964, realised for the first time a population-based register of all multiple births in the Belgian Province of East Flanders, characterized by the systematic examination of the placenta and the accurate determination of zygosity based on blood groups, DNA and structure of fetal membranes. For decades, it has been the only register to include chorionicity in same-sex pairs of twins, an irreplaceable tool allowing almost certain diagnosis of monozygosity and the timing of the division of the zygote.in monozygotic twins. We showed that twins and triplets are far from being an homogenised group and demonstrated differences between these groups important enough to introduce these variables in the standard methodology of twin research. Examples are: Weinberg rule, sex ratio and duration of gestation.


1979 ◽  
Vol 57 (13) ◽  
pp. 1557-1568 ◽  
Author(s):  
Vinod Dave ◽  
J. B. Stothers ◽  
E. W. Warnhoff

Several ring-expansion reactions (diazomethane, diazoacetic ester, Tiffeneau–Demjanov, Baeyer–Villiger, and Schmidt) of 3-keto steroids have been reexamined to determine the true migration ratios for C-2 and C-4 in these unsymmetrical cyclohexanones. Migration ratios were measured to ±3% accuracy by integration of baseline-separated signals in the proton-decoupled 13Cmr spectra of total reaction products. This underexploited method provides for the first time a way to get accurate migration ratios without loss of components during separation and without interference from excess starting material under conditions minimizing side reactions. In contrast to numerous literature reports, all but one of the 16 reactions studied were found to give nearly the same amount of both possible A-homo products. (The single exception was the only reaction in which the A-homo product reacts markedly faster than the starting material.) This simple, consistent ∼1:1 pattern is that expected if migration is governed mainly by the electronic effect of the α- and α′-carbon atoms and not by any conformational or near-by-to-remote substituent effect.


2019 ◽  
Author(s):  
Pascal Hedelt ◽  
Dmitry S. Efremenko ◽  
Diego G. Loyola ◽  
Robert Spurr ◽  
Lieven Clarisse

Abstract. Precise knowledge of the location and height of the volcanic SO2 plumes is essential for accurate determination of SO2 emitted by volcanic eruptions for aviation control applications, but so far very time-consuming to retrieve from UV satellite data. The SO2 height is furthermore one of the most critical parameters that determine the impact on the climate. We have developed an extremely fast yet accurate SO2 layer height retrieval algorithm using the Full-Physics Inverse Learning Machine (FP_ILM) algorithm, which, for the first time, is applied to TROPOMI aboard Sentinel-5 Precursor. In this work we demonstrate the ability of the FP_ILM algorithm to retrieve layer heights in near-real time applications with an accuracy of better than 2 km for SO2 total columns larger than 20 DU and show SO2 layer height results for selected volcanic eruptions.


2016 ◽  
Vol 31 (1) ◽  
pp. 280-287 ◽  
Author(s):  
QingHua Hou ◽  
Lian Zhou ◽  
Shan Gao ◽  
Ting Zhang ◽  
Lanping Feng ◽  
...  

The absolute determination of the Cu isotope ratio in NIST SRM 3114 based on a regression mass bias correction model is performed for the first time with NIST SRM 944 Ga as the calibrant.


2020 ◽  
Author(s):  
Dmitry Efremenko ◽  
Pascal Hedelt ◽  
Diego Loyola ◽  
Robert Spurr

<p>We present here a novel method for the precise and extremely fast retrieval of volcanic SO2 layer height (LH) based on S5P/TROPOMI data. We have developed the Full-Physics Inverse Learning Machine (FP_ILM) algorithm using a combined principal components analysis (PCA) and neural network approach (NN) to extract the information about the volcanic SO2 LH from high-resolution UV backscatter measurement of TROPOMI aboard Sentinel-5 Precursor.</p><p>The SO2 LH is essential for accurate determination of SO2 emitted by volcanic eruptions. So far UV based SO2 plume height retrieval algorithms are very time-consuming and therefore not suitable for near-real-time applications. The FP_ILM approach however enables for the first time to extract the SO2 LH information in a matter of seconds for an entire S5P orbit and thus applicable in NRT application.</p><p>The FP_ILM SO2 LH product is developed as part of ESA’s ‘Sentinel-5p+ Innovation - SO2 Layer Height project’ (S5P+I: SO2 LH) project, dedicated to the generation of an SO2 LH product and its extensive verification with collocated ground- and space-born measurements.</p>


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