Combined Exercise and Cognitive Training System for Dementia Patients: A Randomized Controlled Trial

2018 ◽  
Vol 45 (5-6) ◽  
pp. 318-325 ◽  
Author(s):  
Hitoshi Okamura ◽  
Michiaki Otani ◽  
Naonori Shimoyama ◽  
Takayuki Fujii
Keyword(s):  
Activities Of Daily Living ◽  
Cognitive Training ◽  
Daily Living ◽  
Controlled Trial ◽  
Intervention Group ◽  
Training System ◽  
Control Group ◽  
Combined System ◽  
Combined Exercise ◽  
Dementia Patients

Background/Aims: We investigated the efficacy of a combined exercise and cognitive training system that we devised for improvement of attention and concentration, cognition, and activities of daily living in older adults with dementia. Methods: A total of 100 dementia patients were randomly assigned to an intervention group or a control group. The intervention group was subjected to a combined exercise and cognitive training for 6 consecutive weeks. Evaluations were performed using the Trail Making Test-Part A, the Mini-Mental State Examination, and an N-type activities of daily living evaluation scale for the elderly. Results: A comparison of the changes in scores on the evaluation scales between the intervention group and the control group showed significant interactions for all scores. Conclusions: The combined system is effective in increasing attention and concentration and improving cognitive function and activities of daily living in dementia patients.

EFFECTS OF A GROUP-BASED 8-WEEK MULTICOMPONENT COGNITIVE TRAINING ON COGNITION, MOOD AND ACTIVITIES OF DAILY LIVING AMONG HEALTHY OLDER ADULTS: A ONE-YEAR FOLLOW-UP OF A RANDOMIZED CONTROLLED TRIAL

2019 ◽  
pp. 1-10
Author(s):  
P. Srisuwan ◽  
D. Nakawiro ◽  
S. Chansirikarnjana ◽  
O. Kuha ◽  
P. Chaikongthong ◽  
...  
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Activities Of Daily Living ◽  
Cognitive Training ◽  
Daily Living ◽  
Controlled Trial ◽  
Control Group ◽  
Treatment As Usual ◽  
Healthy Older Adults

ACKGROUND: Cognitive interventions have the potential to enhance cognition among healthy older adults. However, little attention has been paid to the effect of cognitive training (CT) on mood and activities of daily living (ADL). OBJECTIVES: To assess the effectiveness of a multicomponent CT using a training program of executive functions, attention, memory and visuospatial functions (TEAM-V Program) on cognition, mood and instrumental ADL. DESIGN: A randomized, single-blinded, treatment-as-usual controlled trial. SETTING: Geriatric clinic in Bangkok, Thailand. PARTICIPANTS: 77 nondemented community-dwelling older adults (mean age 65.7±4.3 years). INTERVENTION: The CT (TEAM-V) program or the treatment-as-usual controlled group. The TEAM-V intervention was conducted over 5 sessions, with a 2-week interval between each session. Of 77 participants randomized (n=40 the TEAM-V program; n=37 the control group). MEASUREMENTS: The Thai version of Montreal Cognitive Assessment (MoCA), The Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-cog), Thai version of Hospital Anxiety and Depression Scale (HADS) and The Chula ADL were used to assess at baseline, 6 months and 1 year. RESULTS: Compared with the control arm, the TEAM-V Program was associated with reducing anxiety (P = 0.004). Compared with the baseline, participants receiving the TEAM-V Program were associated with significantly improved general cognition (MoCA, P < 0.001), immediate recall (word recall task, P = 0.01), retrieval and retention of memory process (word recognition task, P = 0.01), attention (number cancellation part A, P < 0.001) and executive function (maze test, P = 0.02) at 1 year. No training effects on depression (P = 0.097) and IADL (P = 0.27) were detected. CONCLUSIONS: The TEAM-V Program was effective in reducing anxiety. Even though, the program did not significantly improve cognition, depression and ADL compared with the control group, global cognition, memory, attention and executive function improved in the intervention group compared with baseline. Further studies incorporating a larger sample size, longitudinal follow-up and higher-intensity CT should be conducted.

scholarly journals EFFECTS OF GROUP-BASED MULTICOMPONENT COGNITIVE TRAINING ON COGNITION, MOOD AND INSTRUMENTAL ACTIVITIES OF DAILY LIVING AMONG OLDER PEOPLE LIVING IN THE COMMUNITY

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Patsri Srisuwan ◽  
Daochompu Nakawiro ◽  
Sirinthorn Chansirikarnjana ◽  
Orawan Kuha ◽  
Sayan Janbumrung ◽  
...  
Keyword(s):  
Older Adults ◽  
Older People ◽  
Activities Of Daily Living ◽  
Cognitive Training ◽  
Daily Living ◽  
Intervention Group ◽  
Word Recall ◽  
Anxiety And Depression ◽  
Control Group ◽  
Instrumental Activities

The present study aimed to assess the effectiveness of a multicomponent cognitive training using training of executive functions, attention, memory and visuospatial functions (TEAM-V) Program on cognition, mood and instrumental activities of daily living (IADL) among healthy older adults living in community. Using a single-blinded randomized controlled design, 80 participants were randomized to the TEAM-V or control group. The TEAM-V intervention was conducted for 5 sessions, with 2-week intervals between each session. The Thai version of the Montreal Cognitive Assessment (MoCA), the  Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-cog), the Thai version of the Hospital Anxiety and Depression Scale (HADS) and the Chula ADL were used to assess at baseline and 6 months. Participants receiving the TEAM-V Program were associated with significant improvement in MoCA (P=0.03), word recall task (P=0.01) and word recognition task (P=0.01) scores (subtests of ADAS-cog) versus the control. Both anxiety and depression scores decreased in the intervention group (mean + SD: -0.20±2.15 and -0.43±2.17, respectively). In contrast, both anxiety and depression scores increased in the control group (mean + SD: 0.59±1.98 and 0.76±2.17, respectively). IADL scores increased in the intervention group but not in the control group (mean + SD: 0.13±0.61 and -0.05±0.33, respectively). The TEAM-V Program helped to improve global cognitive function, memory, reduce anxious and depressive symptoms and enhance IADL among healthy older people. Key words: activities of daily livings, cognitive training, mood, older adults

Investigating the Impact of Cognitive Training for Individuals With Bothersome Tinnitus: A Randomized Controlled Trial

2021 ◽  
pp. 019459982199474
Author(s):  
Maggie Xing ◽  
Dorina Kallogjeri ◽  
Jay F. Piccirillo
Keyword(s):  
Randomized Controlled Trial ◽  
Cognitive Training ◽  
Mixed Model ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Functional Index ◽  
Open Label ◽  
Randomized Controlled ◽  
The Impact

Objective To evaluate the effectiveness of cognitive training in improving tinnitus bother and to identify predictors of patient response. Study Design Prospective open-label randomized controlled trial. Setting Online. Methods Participants were adults with subjective idiopathic nonpulsatile tinnitus causing significant tinnitus-related distress. The intervention group trained by using auditory-intensive exercises for 20 minutes per day, 5 days per week, for 8 weeks. The active control group trained on the same schedule with non–auditory intensive games. Surveys were completed at baseline, 8 weeks, and 12 weeks. Results A total of 64 participants completed the study. The median age was 63 years (range, 25-69) in the intervention group and 61 years (34-68) in the control group. Mixed model analysis revealed that within-subject change in Tinnitus Functional Index in the intervention group was not different than the control group, with marginal mean differences (95% CI): 0.24 (–11.20 to 10.7) and 2.17 (–8.50 to 12.83) at 8 weeks and 2.33 (–8.6 to 13.3) and 3.36 (–7.91 to 14.6) at 12 weeks, respectively. When the 2 study groups were compared, the control group had higher Tinnitus Functional Index scores than the intervention group by 10.5 points at baseline (95% CI, –0.92 to 29.89), 8.1 at 8 weeks (95% CI, –3.27 to 19.42), and 9.4 at 12 weeks (95% CI, –2.45 to 21.34). Conclusion Auditory-intensive cognitive training was not associated with changes in self-reported tinnitus bother. Given the potential for neuroplasticity to affect tinnitus, we believe that future studies on cognitive training for tinnitus remain relevant.

scholarly journals Modified Pro-Self Pain Control to Increase Activity in Patients with Colorectal Cancer

2017 ◽  
Vol 7 (1) ◽  
pp. 56
Author(s):  
Khoirunnisa’ Munawaroh ◽  
Untung Sujianto ◽  
Mardiyono Mardiyono
Keyword(s):  
Colorectal Cancer ◽  
Experimental Design ◽  
Activities Of Daily Living ◽  
Pain Control ◽  
Daily Living ◽  
Intervention Group ◽  
Control Group ◽  
Patients With Cancer ◽  
Katz Index ◽  
Significant Difference

Background: Barriers to performing activities of daily living are common complaints of patients with cancer. One of the factors causing these barriers is pain. A modified pro-self pain control is a method used to enhance the patients’ ability to cope with pain to increase their activity.Purpose: This study aimed to evaluate the modified pro-self pain control to increase activity in patients with colorectal cancer undergoing chemotherapy.Methods: The present study employed an experimental design. Patients with colorectal cancer undergoing chemotherapy were randomly assigned to the intervention group (n=24) and the control group (n=24). The patients in the control group were given a standard hospital intervention, while the patients in the intervention group were given the modified pro-self pain control for nine days. The data were collected using the instrument of KATZ index and analyzed using the independent t-test.Results: The result of this study showed that there was a higher increase of activity among the patients in the intervention group than in the control group. Independent t-test showed that there was a significant difference between the intervention group and the control group (p=0.00).Conclusion: The modified pro-self pain control was found more effective to increase the activity in patients with colorectal cancer undergoing chemotherapy than that of the standard hospital intervention. 

Efficacy of Group Reminiscence Therapy on Cognition, Depression, Neuropsychiatric Symptoms, and Activities of Daily Living for Patients With Alzheimer Disease

2019 ◽  
Vol 33 (5) ◽  
pp. 272-281 ◽  
Author(s):  
Mo Li ◽  
Ji-hui Lyu ◽  
Yi Zhang ◽  
Mao-long Gao ◽  
Rena Li ◽  
...  
Keyword(s):  
Alzheimer Disease ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Neuropsychiatric Symptoms ◽  
Intervention Group ◽  
Disease Assessment ◽  
Control Group ◽  
Time Points ◽  
Reminiscence Therapy ◽  
Group Reminiscence

The current study aimed to investigate the effects of group reminiscence therapy on cognitive function, depression, neuropsychiatric symptoms, and activities of daily living in patients with mild-to-moderate Alzheimer disease (AD). A single-blind randomized parallel-design controlled trial was conducted between May 1, 2017, and April 30, 2018. Ninety patients with mild-to-moderate AD recruited from Beijing Geriatric Hospital were randomly allocated into intervention (n = 45) and control groups (n = 45). In the intervention group, group-based reminiscence therapy was performed in two 30- to 45-minute sessions weekly for 12 weeks. Control participants received only conventional drug treatments and routine daily care. Alzheimer disease–related symptoms were evaluated using the Alzheimer’s Disease Assessment Scale-Cognitive section, the Cornell Scale for Depression in Dementia (CSDD), the Neuropsychiatric Inventory, and the Barthel Index. Four time points were set for data collection: baseline (before treatment), 4 weeks (during treatment), 12 weeks (end of treatment), and 24 weeks (12 weeks posttreatment). χ2 Tests, independent t tests, repeated-measures analysis of variance, and Bonferroni tests were used for data analysis. Significant improvements in depressive and neuropsychiatric symptoms were found in the intervention group compared to the control group ( P < .05). Mean CSDD scores in the intervention group were improved at all 3 time points compared to baseline and showed the greatest effect at 12 weeks ( t = 2.076, P = .041) and 24 weeks follow-up ( t = 3.834, P = .000) compared to controls. Group reminiscence therapy was effective for improving depressive symptoms and was beneficial for treating neuropsychiatric symptoms in patients with AD.

scholarly journals Contribution of a multicomponent intervention on functional capacity and independence on activities of daily living in individuals with neurocognitive disorder

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Flávia Borges-Machado ◽  
Duarte Barros ◽  
Laetitia Teixeira ◽  
Oscar Ribeiro ◽  
Joana Carvalho
Keyword(s):  
Activities Of Daily Living ◽  
Functional Capacity ◽  
Daily Living ◽  
Exercise Intervention ◽  
Controlled Trial ◽  
Upper Body ◽  
Control Group ◽  
Neurocognitive Disorder ◽  
Walk Test ◽  
Timed Up And Go

Abstract Background To examine the effects of a 6-month multicomponent (MT) exercise intervention in the functional capacity and ability to independently perform activities of daily living (ADL) of individuals diagnosed with neurocognitive disorder (NCD). Methods A quasi-experimental controlled trial with a parallel design study was conducted in multicentered community-based settings. Forty-three individuals (N Female: 30) were allocated to an exercise group (EG; N: 23; mean 75.09, SD = 5.54 years) or a control group (CG; N:20; mean 81.90, SD = 1.33 years). The EG engaged in a 6-month MT program (60-min sessions, twice a week). Exercise sessions were divided into a warm-up, specific training (e.g., coordination and balance, lower and upper body strength, and aerobics), and cool down. Lower body function, mobility, and gait speed were evaluated through Short Physical Performance Battery (SPPB), Timed-Up and Go test (TUG) and 6-Meter Walk test, respectively. The Barthel Index (BI) was administered to assess individuals’ ADL independence. Evaluations were performed before and after the 6-month intervention. Results Linear Mixed Models revealed a statistically significant interaction (time X group) effect factor on SPPB (B = 2.33, 95% CI: 1.39–3.28, p < 0.001), TUG (B = − 11.15, 95% CI: − 17.23 – − 5.06, p = 0.001), and 6-Meter Walk test (B = 0.17, 95% CI: 0.08–0.25, p < 0.001). No differences between groups or assessment moments were found in the ability of individuals to independently perform ADL. Conclusions The 6-month MT exercise intervention improves the functional capacity of older adults living with NCD. Trial registration ClinicalTrials.gov – identifier number NCT04095962; retrospectively registered on 19 September 2019.

scholarly journals Contribution of a Multicomponent Intervention on Functional Capacity and Independence on Activities of Daily Living in Individuals With Neurocognitive Disorder

2021 ◽  
Author(s):  
Flávia Borges-Machado ◽  
Duarte Barros ◽  
Laetitia Teixeira ◽  
Óscar Ribeiro ◽  
Joana Carvalho
Keyword(s):  
Activities Of Daily Living ◽  
Functional Capacity ◽  
Daily Living ◽  
Exercise Intervention ◽  
Controlled Trial ◽  
Upper Body ◽  
Control Group ◽  
Neurocognitive Disorder ◽  
Walk Test ◽  
Timed Up And Go

Abstract Background: To examine the effects of a 6-month multicomponent (MT) exercise intervention in the functional capacity and ability to independently perform activities of daily living (ADL) of individuals diagnosed with neurocognitive disorder (NCD). Methods: A quasi-experimental controlled trial with a parallel design. This study was conducted in multicentered community-based settings. Forty-three individuals (N Female: 30) were allocated to an exercise group (EG; N: 23; mean 75.09, SD=5.54 years) or a control group (CG; N:20; mean 81.90, SD=1.33 years). The EG engaged in a 6-month MT program (60-min sessions, twice a week). Exercise sessions were divided into a warm-up, specific training (e.g., coordination and balance, lower and upper body strength, and aerobics), and cool down. Lower body function, mobility, and gait speed were evaluated through Short Physical Performance Battery (SPPB), Timed-Up and Go test (TUG) and 6-Meter Walk test, respectively. The Barthel Index (BI) was administered to assess individuals’ ADL independence. Evaluations were performed before and after the 6-month intervention. Results: Linear Mixed Models revealed a statistically significant interaction (time X group) effect factor on SPPB (B = 2.33, 95% CI: 1.39 – 3.28, p < 0.001), TUG (B = -11.15, 95% CI: -17.23 – -5.06, p = 0.001), and 6-Meter Walk test (B = 0.17, 95% CI: 0.08 – 0.25, p < 0.001). No differences between groups or assessment moments were found in the ability of individuals to independently perform ADL.Conclusions: The 6-month MT exercise intervention improves the functional capacity of older adults living with NCD.Trial Registration: ClinicalTrials.gov – identifier number NCT04095962; retrospectively registered on 19 September 2019.

scholarly journals Feasibility of a Cognitive Training Game in Parkinson’s Disease: The Randomized Parkin’Play Study

2020 ◽  
Vol 83 (4) ◽  
pp. 426-432 ◽  
Author(s):  
Sjors C.F. van de Weijer ◽  
Annelien A. Duits ◽  
Bastiaan R. Bloem ◽  
Nienke M. de Vries ◽  
Roy P.C. Kessels ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Training ◽  
Controlled Trial ◽  
Intervention Group ◽  
Waiting List ◽  
Control Group ◽  
Positive Effects ◽  
Home Based ◽  
Global Cognition

Cognitive training (CT) shows modest positive effects on cognitive function in patients with Parkinson’s disease (PD). Gamification may enhance adherence to traditional CT, but this has not been studied yet. Here, we investigated the feasibility of a gamified CT. We performed a randomized controlled trial including PD patients with mild cognitive impairment. Participants were randomly allocated to a 12-week home-based gamified CT intervention or waiting-list control group. Assessments were performed at baseline and at weeks 12 and 24. Forty-one patients were included (21 intervention and 20 waiting-list controls). Sixty-three percent of the intervention group trained >50% of the recommended sessions, while 81% voluntarily continued training after 12 weeks. After 24 weeks, 87.5% graded the game to be satisfactory. Global cognition scores improved after 24 weeks. Home-based gamified CT shows acceptable feasibility in patients with PD, and we observed preliminary indications for efficacy. Larger trials are needed to establish this efficacy.

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