Bibliometric Analysis of the 50 Most Cited Publications in Hidradenitis Suppurativa

2021 ◽  
pp. 1-7
Author(s):  
Justine R. Seivright ◽  
Alyssa M. Thompson ◽  
Natalie M. Villa ◽  
Vivian Y. Shi ◽  
Jennifer L. Hsiao
Keyword(s):  
Medical Treatment ◽  
Paradigm Shift ◽  
Hidradenitis Suppurativa ◽  
Senior Author ◽  
Evidence Based ◽  
Randomized Controlled ◽  
The Past ◽  
Evidence Based Care ◽  
Highly Cited Articles ◽  
Highly Cited

Background: Hidradenitis suppurativa (HS) has historically been a neglected disease. However, research in this field has grown exponentially in the past decade. Methods: The top-cited HS articles from 1950 to 2020 were analyzed for authorship, study topic, study design, and senior author country of origin. Results: We found that nearly half of the top 50 cited articles were published in the last decade, with a recent increase in the number of highly cited randomized controlled trials. Medical treatment is the most cited topic, with more attention on biologics over time. The past decade has seen an increase in highly cited articles on HS comorbidities, pathogenesis, and clinical practice guidelines. There has been a predominance of highly cited HS research from Europe; highly cited studies from Africa, Asia, Australia, and South America are lacking. Conclusions: Recent advances in HS research have focused on investigating HS pathogenesis and drug development, highlighting disease comorbidities, and improving evidence-based care. Studies in pathogenesis have translated into a paradigm shift in medical treatment from antibiotics to incorporation of targeted therapies in recent years. Encouraging growth of HS research in countries outside of North America and Europe may help to optimize HS care globally.

scholarly journals High-cited favorable studies for COVID-19 treatments ineffective in large trials

2022 ◽  
Author(s):  
John P.A. Ioannidis
Keyword(s):  
Clinical Trials ◽  
Randomized Controlled Trials ◽  
Clinical Studies ◽  
Observational Studies ◽  
Randomized Trials ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Wide Dissemination ◽  
Highly Cited Articles ◽  
Highly Cited

Importance. COVID-19 has resulted in massive production, publication and wide dissemination of clinical studies trying to identify effective treatments. However, several widely touted treatments failed to show effectiveness in large well-done randomized controlled trials (RCTs). Objective. To evaluate for COVID-19 treatments that showed no benefits in subsequent large RCTs how many of their most-cited clinical studies had declared favorable results for these interventions. Methods. Scopus (last update December 23, 2021) identified articles on lopinavir-ritonavir, hydroxycholoroquine/azithromycin, remdesivir, convalescent plasma, colchicine or interferon (index interventions) that represented clinical trials and that had received >150 citations. Their conclusions were assessed and correlated with study design features. The ten most recent citations for the most-cited article on each index intervention were examined on whether they were critical to the highly-cited study. Altmetric scores were also obtained. Findings. 40 articles of clinical studies on these index interventions had received >150 citations (7 exceeded 1,000 citations). 20/40 (50%) had favorable conclusions and 4 were equivocal. Highly-cited articles with favorable conclusions were rarely RCTs while those without favorable conclusions were mostly RCTs (3/20 vs 15/20, p=0.0003). Only 1 RCT with favorable conclusions had sample size >160. Citation counts correlated strongly with Altmetric scores, in particular news items. Only 9 (15%) of 60 recent citations to the most highly-cited studies with favorable or equivocal conclusions were critical to the highly-cited study. Conclusion. Many clinical studies with favorable conclusions for largely ineffective COVID-19 treatments are uncritically heavily cited and disseminated. Early observational studies and small randomized trials may cause spurious claims of effectiveness that get perpetuated.

scholarly journals Augmenting Evidence-Based Care With a Texting Mobile Interventionist: A Pilot Randomized Controlled Trial

2020 ◽  
Vol 71 (12) ◽  
pp. 1218-1224
Author(s):  
Dror Ben-Zeev ◽  
Benjamin Buck ◽  
Suzanne Meller ◽  
William J. Hudenko ◽  
Kevin A. Hallgren
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Evidence Based ◽  
Randomized Controlled ◽  
Evidence Based Care ◽  
Pilot Randomized Controlled Trial

Plastic and reconstructive surgery

2016 ◽  
Keyword(s):  
Randomized Controlled Trials ◽  
Plastic Surgery ◽  
Reconstructive Surgery ◽  
Controlled Trials ◽  
Evidence Based ◽  
Trial And Error ◽  
Plastic And Reconstructive Surgery ◽  
Randomized Controlled ◽  
The Past ◽  
Evidence Based Surgery

In plastic and reconstructive surgery, innovation and creativity have been foremost, with science and evidence following. Unlike for a number of other specialties, the advances in plastic surgery have largely come from imagination, innovations, and trial and error, rather than from scientific trials. Somewhat more than for the rest of surgery, in plastics (where the art and craft of each particular surgeon counts immeasurably), randomized controlled trials of techniques have failed to be generated in the past, due to the difficulty of objectively assessing the success of surgery with an aesthetic-based nature. Consequently, evidence-based study of plastic surgery is a relatively new and developing field. This chapter focuses on the growing importance of evidence-based surgery in this specialty, showing that scientific trials are now being performed with increasing frequency.

Characteristics of highly cited articles in heart failure: a bibliometric analysis

2020 ◽  
Vol 16 (3) ◽  
pp. 189-197
Author(s):  
Izza Shahid ◽  
Vanita Motiani ◽  
Tariq Jamal Siddiqi ◽  
Muhammad Shariq Usman ◽  
Jai Kumar ◽  
...  
Keyword(s):  
Heart Failure ◽  
Bibliometric Analysis ◽  
Senior Author ◽  
Research Activity ◽  
Vast Array ◽  
Research Areas ◽  
Author Position ◽  
Number Of Citations ◽  
Highly Cited Articles ◽  
Highly Cited

Aim: Despite a vast array of research in heart failure (HF), no bibliometric analysis has been conducted for HF. Therefore, we sought to identify in-depth characteristics of 100 most cited publications in HF. Materials & methods: Two independent reviewers searched the Scopus Library Database using a variety of keywords to extract the top 100 articles. Results: Majority (36%) of top 100 cited articles were published between 2001 and 2005. The total number of citations ranged from 6294 to 1003. Females had less than a quarter representation in both first and senior author position. More than three-fourths (86%) of the articles were funded. Conclusion: Our analysis highlights focal areas of research activity in order to guide HF specialists toward impactful research areas.

Randomized controlled trials (RCTs) examining continuous (CS) versus intermittent strategies (IS) of delivering systemic treatment (Tx) for untreated metastatic colorectal cancer (mCRC): A meta-analysis from the Cancer Care Ontario program in evidence-based care.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 3534-3534 ◽  
Author(s):  
Scott R. Berry ◽  
Roxanne Cosby ◽  
Timothy R. Asmis ◽  
Kelvin K. Chan ◽  
Nazik Hammad ◽  
...  
Keyword(s):  
Systemic Treatment ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Controlled Trials ◽  
Evidence Based ◽  
Random Effects Model ◽  
Randomized Controlled ◽  
Hazard Ratios ◽  
Evidence Based Care ◽  
Review Manager

3534 Background: Given the varying impact on efficacy demonstrated in individual RCTs of CS vs IS of delivering systemic Tx for mCRC, a meta-analysis of the available RCTs was performed. Methods: RCTs that compared a CS versus IS of delivering systemic Tx were identified by a systematic search (MEDLINE, EMBASE and ASCO and ESMO proceedings) and review. The results of identified trials were clinically homogeneous (Table) so the data was pooled using Review Manager software (RevMan 5.2). Overall survival (OS) hazard ratios were extracted directly from the most recently reported trial results. A random effects model was used for all pooling. Results: 10 RCTs were identified (n= 4,296). After an induction period, the maintenance Tx patients received during the IS was: none (5 trials, n=2,562), fluoropyrimidine (F) (2 trials, n=759), biologic (B) (2 trials, n=852), F+B (1 trial, n=123). Results of the meta-analysis are summarized in the Table (HR>1 favors CS). Sensitivity analyses performed demonstrate results are robust independent of the induction or maintenance Tx used. QOL (data from 2 trials) was either the same in both arms (single Tx induction trial with no maintenance Tx, n=354) or improved in the IS arm (combination tx induction trial with no maintenance Tx, n=1,630). Conclusions: IS of delivering systemic Tx for mCRC do not result in a statistically significant reduction in OS compared to a CS of delivery whether or not maintenance therapy is included. QOL is the same or better with an IS. [Table: see text]

scholarly journals The effectiveness of enhanced evidence-based care for depressive disorders: a meta-analysis of randomized controlled trials

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Le Xiao ◽  
Han Qi ◽  
Wei Zheng ◽  
Yu-Tao Xiang ◽  
Thomas J. Carmody ◽  
...  
Keyword(s):  
Randomized Controlled Trials ◽  
Usual Care ◽  
Depressive Disorders ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Evidence Based ◽  
Randomized Controlled ◽  
Measurement Based Care ◽  
Evidence Based Care

AbstractSeveral care models have been developed to improve treatment for depression, all of which provide “enhanced” evidence-based care (EEC). The essential component of these approaches is Measurement-Based Care (MBC). Specifically, Collaborative Care (CC), and Algorithm-guided Treatment (AGT), and Integrated Care (IC) all use varying forms of rigorous MBC assessment, care management, and/or treatment algorithms as key instruments to optimize treatment delivery and outcomes for depression. This meta-analysis systematically examined the effectiveness of EEC versus usual care for depressive disorders based on cluster-randomized studies or randomized controlled trials (RCTs). PubMed, the Cochrane Library, and PsycInfo, EMBASE, up to January 6th, 2020 were searched for this meta-analysis. The electronic search was supplemented by a manual search. Standardized mean difference (SMD), risk ratio (RR), and their 95% confidence intervals (CIs) were calculated and analyzed. A total of 29 studies with 15,255 participants were analyzed. EEC showed better effectiveness with the pooled RR for response of 1.30 (95%CI: 1.13–1.50, I2 = 81.9%, P < 0.001, 18 studies), remission of 1.35 (95%CI: 1.11–1.64, I2 = 85.5%, P < 0.001, 18 studies) and symptom reduction with a pooled SMD of −0.42 (95%CI: −0.61–(−0.23), I2 = 94.3%, P < 0.001, 19 studies). All-cause discontinuations were similar between EEC and usual care with the pooled RR of 1.08 (95%CI: 0.94–1.23, I2 = 68.0%, P = 0.303, 27 studies). This meta-analysis supported EEC as an evidence-based framework to improve the treatment outcome of depressive disorders.Review registration: PROSPERO: CRD42020163668

scholarly journals Visualizing highly cited scientific output of Indian physiotherapists: A bibliometric study

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 207
Author(s):  
Arun Vijay Subbarayalu ◽  
Manuelraj Peter ◽  
Mohamed Idhris ◽  
Sivasankar Prabaharan ◽  
Muhil Sakthivel ◽  
...  
Keyword(s):  
Web Of Science ◽  
Descriptive Study ◽  
Scientific Output ◽  
Future Research ◽  
Evidence Based ◽  
The Past ◽  
Research Collaborations ◽  
Increasing Trend ◽  
Number Of Citations ◽  
Highly Cited

Background: Physiotherapy research supports the advancement of evidence-based practice and development of a highly skilled workforce. This study aims to visualize highly cited scientific output of Indian physiotherapists from 1999 to 2018. Methods: A descriptive study design was adopted to visualize highly cited scientific output of Indian physiotherapists using the Web of Science (WoS) database from 1999 to 2018. A search was carried out using the following term "((TS=(physiotherapy) OR TS=("physical rehabilitation") OR TS=("physical therapy")) AND AD=(India))Indexes=SCI-EXPANDED, SSCI, A&HCI, CPCI-S, CPCI-SSH, ESCI, CCR-EXPANDED, IC Timespan=1999-2018”. Data collected were analyzed using Incites from WoS and VOSviewer software. Results:  A total of 489 articles were published between 1999 and 2018, with a peak of 103 in 2016 with 2420 citations. A decline in publication count was observed after 2016. The journal International Journal of Physiotherapy published the highest number of articles (n=35). Manipal University (n=26) was found to be the most active institution for physiotherapy research in India, as determined by producing the most articles. Indian physiotherapists published the highest number of research articles in collaboration with US authors (n=24). Conclusion: There is an increasing trend in the scientific output of Indian physiotherapists over the past two decades; however, a decline is observed after 2016. It is recommended that research collaborations across the globe are increased and scientific output should be improved, leading to a higher number of citations. Future research should explore factors influencing scientific production of Indian physiotherapists and devise appropriate strategies to attain further improvement.

Randomized experiments in Scandinavian criminal justice: Reviewing the past and looking to the future

2018 ◽  
Vol 17 (2) ◽  
pp. 224-244 ◽  
Author(s):  
Synøve N. Andersen ◽  
Jordan Hyatt
Keyword(s):  
Controlled Trials ◽  
Evidence Based ◽  
Randomized Experiments ◽  
Psychological Treatments ◽  
Randomized Controlled ◽  
The Past ◽  
Experimental Criminology ◽  
Counter Narrative ◽  
American Research ◽  
Policy Solutions

Randomized controlled trials are reported on with increasing frequency within the criminological literature. This development, which is commonly seen as being a part of a global shift towards evidence-based policies, relies heavily on reviews of American research. However, other regions face distinct challenges and employ distinct policy solutions, potentially undermining the uniformity of this trend. In particular, the Scandinavian nations (Denmark, Norway and Sweden), with distinct penal philosophies, may offer a counter-narrative. Here, we conduct a multi-lingual systematic review of crime-related experiments in Scandinavia. Findings show that only eight experiments with an offending or delinquency outcome were published before 2015, six of which focused primarily on medical or psychological treatments. We suggest this distribution is driven by unique, regional epistemological traditions and conclude by outlining distinctive opportunities for experimental criminology in Scandinavia.

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