Concurrence of 1- and 3-Min Sit-to-Stand Tests with the 6-Min Walk Test in Idiopathic Pulmonary Fibrosis

Respiration ◽  
2021 ◽  
pp. 1-9
Author(s):  
Arnaud Fedi ◽  
Sophia Keddache ◽  
Sébastien Quétant ◽  
Alicia Guillien ◽  
Anestis Antoniadis ◽  
...  

<b><i>Background:</i></b> In idiopathic pulmonary fibrosis (IPF), some physiological parameters measured during a 6-min walk test (6-MWT) impart reliable prognostic information. Sit-to-stand tests (STSTs) are field exercise tests that are easier to implement than the 6-MWT in daily practice. <b><i>Objectives:</i></b> The aims of the study were to test the reproducibility and compare 2 STSTs (the 1-min STST [1-STST] and the semi-paced 3-min chair rise test [3-CRT]) in IPF, and to determine if selected physiological parameters (speed of displacement and changes in pulse oxygen saturation [SpO<sub>2</sub>]) are interchangeable between the STSTs and the 6-MWT. <b><i>Methods:</i></b> Thirty-three patients with stable IPF were studied in 3 French expert centers. To test reproducibility, intra-class correlations (ICCs) of parameters measured during tests performed 7–14 days apart were calculated. To test interchangeability, the agreement and correlation of physiological responses measured during STSTs and during 6-MWT were studied. <b><i>Results:</i></b> Vertical displacements and changes in SpO<sub>2</sub> during both STSTs were reproducible, with ICCs ranging from 0.78 [0.63–0.87] to 0.95 [0.92–0.97]. Vertical displacements during 1-STST and 3-CRT were correlated with 6-MWT distance (correlation coefficients (<i>r</i>) of 0.72 and 0.77, respectively; <i>p</i> &#x3c; 0.001). Similarly, correlations were found between changes in SpO<sub>2</sub> measured during the 2 STSTs and the 6-MWT, with coefficients ranging from 0.73 to 0.91 (<i>p</i> &#x3c; 0.001). Distance walked and SpO<sub>2</sub> during 6-MWT were well estimated from vertical displacement and SpO<sub>2</sub> during the 2 STSTs, respectively. <b><i>Conclusion:</i></b> The correlations found between the 2 STSTs and the 6-MWT suggest that STSTs may be of interest to assess displacement and exercise-induced changes in SpO<sub>2</sub> in IPF patients.

2021 ◽  
Vol 100 ◽  
pp. 106227
Author(s):  
Lisa Lancaster ◽  
Ann Fieuw ◽  
Joyce Meulemans ◽  
Paul Ford ◽  
Steven D. Nathan

Author(s):  
Shinichi Arizono ◽  
Yasuhiro Kondoh ◽  
Tomoki Kimura ◽  
Kensuke Kataoka ◽  
Tomoya Ogawa ◽  
...  

2012 ◽  
Vol 106 (11) ◽  
pp. 1613-1621 ◽  
Author(s):  
Omar A. Minai ◽  
Jose F. Santacruz ◽  
Joan M. Alster ◽  
Marie M. Budev ◽  
K. McCarthy

2021 ◽  
Vol 42 (3) ◽  
pp. 375-384
Author(s):  
Sung-eun Hong ◽  
Sung-woo Kang ◽  
Ji-won Park ◽  
Kwon-jun Jang ◽  
Su-hyeon Park ◽  
...  

Objective: This study was designed to analyze the clinical features of idiopathic pulmonary fibrosis patients who attended a Korean medicine hospital and the treatment effects through retrospective chart reviews.Methods: The medical records of 82 outpatients who had been diagnosed with idiopathic pulmonary fibrosis and visited the Allergy, Immune, and Respiratory System Department of Kyung Hee Korean Medicine Hospital from 8 January 2015 to 8 January 2021 were retrospectively reviewed. To assess the treatment outcomes, we used the FVC (Forced Vital Capacity), DLCO (Diffusing capacity of the Lung for CO), 6-minute walk test, and HRCT (High Resolution Computed Tomography).Results: The study group consisted of 28 females and 54 males. The median age of the patients was 67.98±11.44 years. The chief complaints were cough (n=51) and dyspnea (n=49). Other frequent symptoms were general weakness (n=8), weight loss (n=4), and a fever (n=2). A total of 77 (93.90%) patients were prescribed Korean herbal medicine, and 52 (63.41%) patients were treated with acupuncture, moxibustion, cupping therapy, ICT, or pharmacopuncture. After treatments, FVC, DLCO, the 6-minute walk test, and HRCT were maintained or worsened slightly.Conclusions: This study presented the characteristics of idiopathic pulmonary fibrosis patients treated by Korean medical therapies, and further studies of Korean medical treatments for idiopathic pulmonary fibrosis patients would be valuable.


2020 ◽  
Vol 30 (11) ◽  
pp. 6285-6292
Author(s):  
Ana Adriana Trusculescu ◽  
Diana Manolescu ◽  
Emanuela Tudorache ◽  
Cristian Oancea

Abstract Interstitial lung diseases are a diverse group of disorders that involve inflammation and fibrosis of interstitium, with clinical, radiological, and pathological overlapping features. These are an important cause of morbidity and mortality among lung diseases. This review describes computer-aided diagnosis systems centered on deep learning approaches that improve the diagnostic of interstitial lung diseases. We highlighted the challenges and the implementation of important daily practice, especially in the early diagnosis of idiopathic pulmonary fibrosis (IPF). Developing a convolutional neuronal network (CNN) that could be deployed on any computer station and be accessible to non-academic centers is the next frontier that needs to be crossed. In the future, early diagnosis of IPF should be possible. CNN might not only spare the human resources but also will reduce the costs spent on all the social and healthcare aspects of this deadly disease. Key Points • Deep learning algorithms are used in pattern recognition of different interstitial lung diseases. • High-resolution computed tomography plays a central role in the diagnosis and in the management of all interstitial lung diseases, especially fibrotic lung disease. • Developing an accessible algorithm that could be deployed on any computer station and be used in non-academic centers is the next frontier in the early diagnosis of idiopathic pulmonary fibrosis.


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