Keratoacanthoma associated to cutaneous horn manifestation: case report and difficulty of diagnosis

Background: Cutaneous horn (CH) is a conical hyperkatotic projection of skin with keratotic material. A broad variety of lesions may be found with clinical aspect of cutaneous horn, including malignant tumors. Case report: We report a case of patient with 77- year-old male, presenting an asymptomatic lesion with clinical aspect of CH in lower lip. The clinical diagnosis hypothesis was squamous cell carcinoma (SCC) and an incisional biopsy was performed. The histopathological analysis revealed a keratoacantoma (KA) and the lesion was completely removed. The one year follow-up revealed no recurrence. Discussion: CH rarely is accompanied by KA. However, KA shows a greater degree of nuclear atypia than SCC making the differentiation of two diseases very difficult. This case highligh the importance of histopathological examination to rule out malignancy.

Download Full-text

Dermal fibrosarcoma in a Cashmere goat

Tierärztliche Praxis Ausgabe G Großtiere / Nutztiere ◽

10.1055/a-0858-0545 ◽

2019 ◽

Vol 47 (03) ◽

pp. 192-195

Author(s):

Julia Schoiswohl ◽

Bianca Lambacher ◽

Andrea Klang ◽

Reinhild Krametter-Frötscher

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Connective Tissue ◽

Malignant Tumors ◽

Histopathological Examination ◽

Low Grade ◽

Cashmere Goat ◽

Short Lifespan ◽

Production Processes

AbstractFibrosarcomas are malignant tumors of the connective tissue, which are characterized by proliferation of fibroblasts. Most of these tumors are localized subcutaneously and cause different symptoms depending on their location. The case report describes a dermal tumor on the outside of the pinna in a 7-year-old female Cashmere goat. The tumor was surgically removed and histopathological examination revealed a low grade fibrosarcoma. Although tumors are rare in ruminants because of the animals’ short lifespan (age of slaughtering in most cases < 24 months) in modern production processes, they should be considered as a differential diagnosis.

Download Full-text

Unclear Retroperitoneal Tumors, an Interdisciplinary Challenge – A Case Report and Review of the Literature

10.21203/rs.3.rs-798918/v1 ◽

2021 ◽

Author(s):

Benno Traub ◽

Benedikt Haggemüller ◽

Lisa Baumann ◽

Johannes Lemke ◽

Doris Henne-Bruns ◽

...

Keyword(s):

Case Report ◽

Clinical Symptoms ◽

Malignant Tumors ◽

Tumor Resection ◽

Vena Cava ◽

Retroperitoneal Tumors ◽

Common Clinical Presentation ◽

One Year ◽

The Right ◽

Upper Abdomen

Abstract BackgroundUnclear retroperitoneal tumors still impose major challenges for clinicians. Tumors can originate primarily from retroperitoneal tissue or secondarily invade into the retroperitoneal space. While benign lesions also occur, malignant tumors are far more common. Clinical presentation often depends on replacement or invasion of other organs and is therefore highly variable. The heterogeneous tumor composition makes a definitive preoperative diagnosis difficult. Nevertheless, surgical resection is the gold standard for treatment but often proves challenging due to frequent involvement of large retroperitoneal vessels.Case presentationWe present a case report of a 70-year old woman diagnosed with a large, unclear retroperitoneal tumor. Initial clinical symptoms were increasing dyspnea and dysphagia in our clinic. Gastroenterologic and cardiologic workup was unremarkable. Computed Tomography (CT) revealed a large retroperitoneal mass in the right upper abdomen with severe displacement of the inferior vena cava and renal veins. Without signs of irresectability, the patient was scheduled for tumor resection. The procedure was challenging due to the vessel involvement and large blood pressure alterations during tumor mobilization. The post-op pathologic workup then revealed the rare finding of a completely resected paraganglioma. The post-surgical course was uneventful. One year after diagnosis, the patient is relapse-free.CconclusionThis case impressively shows the challenges of retroperitoneal tumors and the importance of interdisciplinary work in these cases.

Download Full-text

A case report and literature review: post-traumatic mammary myofibroblastoma

International Surgery Journal ◽

10.18203/2349-2902.isj20191283 ◽

2019 ◽

Vol 6 (4) ◽

pp. 1385 ◽

Cited By ~ 1

Author(s):

Hadi Abdullah Alaskar ◽

Ahmed Mohammed AlMuhsin ◽

Mirza Faraz Saeed ◽

Amro Salem

Keyword(s):

Case Report ◽

Malignant Tumors ◽

Surgical Excision ◽

Excisional Biopsy ◽

Clinical Findings ◽

Histopathological Analysis ◽

Minor Trauma ◽

Elderly Age ◽

Rare Benign Tumor ◽

A Minor

Mammary myofibroblastoma is a rare benign tumor of the breast, with a higher incidence in elderly age group. It is diagnosed via radiologic and histologic findings, as clinical findings share the same presentation with other, more common, benign breast pathologies. Surgical excision is the only treatment modality used to treat this tumor. We report the case of a 56-years-old-male, who presented with the complaint of left-sided chest swelling for 1 year following a minor trauma to the chest. Ultrasonographic imaging of the mass was the initial investigation and it revealed a well-defined hypoechoic lesion, excisional biopsy was done, followed by histopathological analysis of the mass, which gave the diagnosis of mammary myofibroblastoma. The aim of this case-report is to further study and characterize this rare lesion and its relationship to previous minor or major trauma and other risk factors, in addition, a proper diagnosis should be taken when encountering a similar mass as it mimics many benign and malignant tumors, furthermore a follow up plan should be established to assess the rate of possible recurrence.

Download Full-text

Epithelioid sarcoma of femoral nerve: A case report

Vojnosanitetski pregled ◽

10.2298/vsp160819350i ◽

2018 ◽

Vol 75 (5) ◽

pp. 521-524

Author(s):

Dejan Ivanov ◽

Mirjana Zivojinov ◽

Milan Ranisavljevic

Keyword(s):

Case Report ◽

Soft Tissue ◽

Malignant Tumors ◽

Epithelioid Sarcoma ◽

Femoral Nerve ◽

Hematopoietic Progenitor Cell ◽

Histopathological Analysis ◽

Cancer Antigen 125 ◽

Secondary Tumor ◽

Malignant Soft Tissue Tumor

Introduction. Epithelioid sarcoma is a slow-growing malignant soft tissue tumor and occurs approximately in 1% of all soft tissue malignant tumors. This case report describes epithelioid sarcoma in femoral nerve and as we know it is the first described case of epithelioid sarcoma at this anatomical localisation. Case report. A 44-years-old female patient presented with strong pain in her left leg. On magnetic resonance imaging (MRI), tumor was presented as a node 8 cm in the diameter at left femoral nerve between ileopsoas and iliacus muscle, without infiltration of muscle fascia and tendons. Four enlarged lymph nodes described in left iliac fosa, were suspected on secondary tumor deposits. We preformed radical surgical excision of the tumor and femoral nerve transection with local lymp hnode disection. Histopathological analysis revealed epithelioid sarcoma, and tumor stained highly positive for anti-pan cytokeratin antibody (AE1/AE3), vimentin, cancer antigen 125 (CA125), anticytokeratin antibody (MNF116), hematopoietic progenitor cell antigen (CD34) and epithelial membrane antigen (EMA) markers. After the operation patient recived radiotherapy without chemotherapy. Six months postoperatively, there was no evidence of local relapses or distant metastases. Conclusion. Initial wide surgical resection and adjuvant radiotherapy is beneficial in treatment of epitheloid sarcoma.

Download Full-text

Histiocytosis x: Recurrent isolated mandibular lesion (case report)

Stomatoloski glasnik Srbije ◽

10.2298/sgs0304202b ◽

2003 ◽

Vol 50 (4) ◽

pp. 202-204

Author(s):

Gordana Basta-Jovanovic ◽

Predrag Stefanovic ◽

Milena Jovanovic ◽

Marko Arizanovic

Keyword(s):

Case Report ◽

Cystic Lesion ◽

Iliac Crest ◽

Histiocytosis X ◽

Histopathological Analysis ◽

Laboratory Findings ◽

Cystic Formation ◽

Mandibular Body ◽

Mandibular Defect ◽

One Year

Histiocytosis X usually affects children and adolescents. In our case, a 54-year-old woman was admitted to hospital for evaluating and treatment of an isolated, painless swelling of the left side of the mandible. Orthopanthomogram showed a cystic formation located on the left side of the mandibular body. Radiographs of the scull and body showed no pathologic changes. Laboratory findings did not reveal any abnormality. Surgical enucleation of the mandibular cystic lesion was performed and histopathological analysis confirmed the presence of histiocytosis X. One year after the first operation a relapse formation was found and surgically removed. Resection of the left side of the mandibular body was performed immediately followed by reconstruction of the mandibular defect with free osseos graft taken from the iliac crest. All follow-ups in the period of three years after the second operation showed no sign of relapse.

Download Full-text

Case Report: Solitary mastocytoma treated successfully with topical tacrolimus

F1000Research ◽

10.12688/f1000research.3253.1 ◽

2014 ◽

Vol 3 ◽

pp. 181 ◽

Cited By ~ 4

Author(s):

M. S. Sukesh ◽

Ameet Dandale ◽

Rachita Dhurat ◽

Ankur Sarkate ◽

Smita Ghate

Keyword(s):

Case Report ◽

Rare Case ◽

Topical Tacrolimus ◽

Triggering Factors ◽

Cutaneous Mastocytosis ◽

One Year ◽

The One ◽

Solitary Mastocytoma

Solitary mastocytoma, a rare dermatological entity accounts for 10-15% of cutaneous mastocytosis. We report a rare case of solitary mastocytoma presenting at birth, treated successfully with topical tacrolimus. Along with reassurance and strict avoidance of triggering factors, no recurrence was reported within the one year follow-up period.

Download Full-text

Acute abdominal pain induced by renal leiomyoma in a young patient: a case report

Journal of International Medical Research ◽

10.1177/03000605211032802 ◽

2021 ◽

Vol 49 (7) ◽

pp. 030006052110328

Author(s):

Weina Ma ◽

Huali Jiang ◽

Yunzhen Zhang ◽

Jian Zhang ◽

Hualong Jiang

Keyword(s):

Abdominal Pain ◽

Case Report ◽

Renal Carcinoma ◽

Acute Abdominal Pain ◽

Histopathological Examination ◽

Good Condition ◽

Imaging Features ◽

Renal Capsule ◽

Clinical Imaging ◽

One Year

Renal leiomyoma is a rare benign mesenchymal tumor of the kidney that predominantly originates from the renal capsule or pelvis. However, because of its nonspecific clinical and imaging features, renal leiomyoma remains poorly characterized and may even lead to radical or partial nephrectomy on the basis of preoperative suspicion of renal carcinoma. We herein present a case involving a 12-year-old boy with acute abdominal pain who was diagnosed with renal leiomyoma based on both clinical imaging and histopathological examination. One year after radical nephrectomy, the patient recovered to good condition. This case demonstrates that the comprehensive application of imaging and histology are essential for early clinical diagnosis and effective treatment of renal leiomyoma.

Download Full-text

ORAL SQUAMOUS PAPILLOMA: A CASE REPORT OF 5 YEAR OLD LESION WITH REVIEW OF LITERATURE

10.36106/ijsr/0625681 ◽

2020 ◽

pp. 1-2

Author(s):

Priyansha Rathore ◽

Shiva Shankar Gummaluri

Keyword(s):

Case Report ◽

Oral Cavity ◽

Soft Palate ◽

Histopathological Examination ◽

Review Of Literature ◽

Lower Lip ◽

Squamous Papilloma ◽

Verruciform Xanthoma ◽

The Common

Squamous papilloma is one of the common lesions of oral cavity. These are about less than 1cm size and care should be taken in diagnosing them as they resemble verruciform xanthoma, condyloma etc . Papilloma occurs most commonly on tongue, lips and soft palate. We present a case report of oral squamous papilloma that occurred on right labial mucosa of lower lip. Tissue was surgically excised and subjected to histopathological examination. Histopathological reports confirmed the lesion as squamous papilloma. Post operatively patient had no complications and healing was fine.

Download Full-text

Primary Cutaneous Mucinous Carcinoma Presenting as an Unusually Large Lesion - A Rare Case Report

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2021/599 ◽

2021 ◽

Vol 10 (34) ◽

pp. 2939-2941

Author(s):

Jiby Soosen Ninan ◽

Ajithakumari K. ◽

Tony Mathew

Keyword(s):

Case Report ◽

Histopathological Examination ◽

Mucinous Carcinoma ◽

Malignant Tumour ◽

Large Size ◽

Rare Case Report ◽

Eccrine Carcinoma ◽

One Year ◽

The Right ◽

Adnexal Tumour

Primary cutaneous mucinous carcinoma (PCMC) also known as primary mucinous carcinoma of the skin (PMCS) or primary mucinous eccrine carcinoma (PMEC) is a rare malignant adnexal tumour of eccrine origin. Many visceral mucinous carcinomas especially of the breast and gastrointestinal tract can metastasize to the skin mimicking PCMC. Hence it is very important to rule out metastatic mucinous carcinomas before making a diagnosis of PCMC. Usually, PCMC presents as a slowgrowing tumour of considerably smaller size compared to our case. The large size and shorter duration are the key features of this case report. Here we report an unusually large-sized rare malignant tumour of skin appendage. Our patient was a 54-year-old lady who presented with progressive swelling of one year duration in the right frontoparietal area. Ultrasonography showed an ill-defined lesion in the subcutaneous plane with multiple cystic spaces within it. No bone involvement was noted. The excised lesion measured 13 x 7 x 2 cms and was diagnosed as primary cutaneous mucinous carcinoma on histopathological examination. The possibility of cutaneous secondaries from elsewhere was ruled out by detailed clinical and radiological investigations. The case is reported considering the unusually bigger size and shorter duration of this rare entity.

Download Full-text

Papillary Carcinoma of Thyroid in Thyroglossal Cyst- A Case Report

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/50276.15321 ◽

2021 ◽

Author(s):

RB Namasivaya Navin ◽

S Rajasekaran ◽

PN Aswin Vaishali ◽

K Priya ◽

S Prabakaran

Keyword(s):

Case Report ◽

Papillary Carcinoma ◽

Histopathological Examination ◽

Correct Diagnosis ◽

Thyroglossal Duct Cyst ◽

Duct Cyst ◽

Thyroglossal Duct ◽

Incomplete Removal ◽

Thyroglossal Duct Cysts ◽

One Year

Thyroglossal duct cysts are most commonly occurring congentinal midline swellling of the neck. Usually carcinomas in thyroglossal duct cysts is extremely rare, commonly known as papillary carcinomas. However, the diagnosis is only made postoperatively after excision of the cyst. Although the Sistrunk procedure is often regarded as adequate but controversies exist, the need for thyroidectomy is based on histopathological findings. This is a case report of 43-year-old male presenting with swelling in the midline of the neck for one year. On examination, a cystic swelling was present in the midline of the anterior aspect of the neck. Ultrasonography (USG) neck revealed heteroechoic cystic lesion with solid component and microcalcifications present within the cyst suggestive of thyroglossal duct cyst probably neoplastic. The mass was surgically excised and sent for histopathological examination and reported as thyroglossal duct cyst with papillary carcinoma of thyroid. Appropriate history, clinical examination and investigation leads to the correct diagnosis and treatment. Incomplete removal of the mass leads to recurrence. Histopathological examination is a must postoperatively. The patient is still on follow-up and no recurrence have been noted.

Download Full-text