scholarly journals Quantitative and qualitative index for diagnosing osteopenia and osteoporosis in post-menopausal women

Author(s):  
Lituânia Fialho de Miranda ◽  
Denise Sabbagh Haddad ◽  
Emiko Saito Arita ◽  
Plauto Christopher Aranha Watanabe

<p><strong>Objective:</strong> The objective of this study was to devise a qualitatively and quantitatively reliable index for screening changes in mandibular bone density based on digital panoramic radiographs.</p><p><strong>Methods:</strong> A total of 252 panoramic radiographs and forearm bone densitometry scans of menopausal and post-menopausal women were examined. Diagnosis of osteopenia or osteoporosis was confirmed by comparing forearm densitometry diagnostic reports against diagnoses from radiographs.</p><p><strong>Results:</strong> Pearson’s tests showed a significant association between assessments by the Quantitative and Qualitative Panoramic Index (QQPI) based on panoramic radiography of the mandible and by densitometry (p &lt; 0.001). The Kappa statistic also revealed significant agreement between the two methods of assessment (p &lt; 0.001). A significant association was also found between results of panoramic radiographic assessments of left and right mandible sides (Kappa = 0.676; p &lt; 0.001).</p><p><strong>Conclusion:</strong> These results allowed confirmation of panoramic radiography as a useful method for detecting morphologic age-related changes in the mandible and creation of a single Quantitative and Qualitative Panoramic Index (QQPI) to aid the diagnosis of mandibular osteopenia/osteoporosis.</p>

2017 ◽  
Vol 20 (2) ◽  
pp. 52-56
Author(s):  
Azhari Azhari

The alveolar process is the most supporting tooth containing trabeculae and has the highest metabolic rate in the mandibular body of post-menopausal women. The decreasing in estrogens level on post-menopausal women results a faster reaction than men for 2-3 times. This research aims to determine the bone quality based on trabeculae alveolar process analysis using panoramic radiographs. The research methodology was to conduct 67 samples of panoramic radiographs from RSGM Unpad.  This research applied observational analytic methodology by taking cross-sectional data using secondary data on three groups of bone quality based on measurement using DEXA t-score (normal, osteopenia and osteoporosis). The panoramic radiograph data processing was conducted with Image J software by separating the background and foreground (trabeculae). A focus of 30x30 mm ROI in the alveolar distal portion of the left and right mandibular second premolar teeth, and calculation of trabecular area. Result: average of normal trabecular area: 82.35%, osteopenia: 73.9% and osteoporosis: 68.7% respectively. The difference between normal and osteoporosis was discovered, but no difference was found between normal and osteopenia with p <0.05. This research concludes that the region of interest trabecular of alveolar process with panoramic radiograph can be used to detect osteoporosis on post-menopausal women.


2019 ◽  
Vol 48 (2) ◽  
pp. 20180254 ◽  
Author(s):  
Camila Nao Kato ◽  
Núbia PK Tavares ◽  
Sâmila G Barra ◽  
Tânia MP Amaral ◽  
Cláudia B Brasileiro ◽  
...  

2009 ◽  
Vol 22 (2) ◽  
pp. 332-335 ◽  
Author(s):  
Mark A. Rodrigues ◽  
Jonathan K. Foster ◽  
Giuseppe Verdile ◽  
Karen Joesbury ◽  
Richard Prince ◽  
...  

Alzheimer's disease (AD) is the major form of age-related dementia worldwide, accounting for more than two-thirds of all dementia cases. The disease is characterized by a progressive loss of cognitive and intellectual functioning (Gilman, 1997). A number of risk factors for AD have been identified. The prevalence of AD increases with age, diabetes, depression, family history of Parkinson's disease and following head injury or exposure to solvents (Jorm et al., 1991; van Duijn et al., 1991; Ott et al., 1995; Yoshitake et al., 1995; Devanand et al., 1996). Published research further suggests that low education levels are associated with increased prevalence of clinical AD (Gatz et al., 2001; Qiu et al., 2001; Ravaglia et al., 2002). Women also have a higher risk for developing the disease than men, with the risk being markedly increased following menopause (Sherwin, 2002; Sherwin 2003). Additionally, slightly more severe cognitive deficits have been reported in AD in women compared to men (Buckwalter et al., 1993, Henderson and Buckwalter, 1994). These epidemiological trends may be a consequence of reproductive hormonal changes. Specifically, menopause results in a marked diminution in gonadal estrogen production in women (see Sherwin, 2003, for a review). Estrogen plays a pivotal role in the maintenance and function of neuronal circuits in the brain and in resistance to neuronal damage (McEwen, 2001). The neuroprotective properties of estrogen are thought to be mediated at least in part by anti-amyloidogenic, anti-oxidative and ant-inflammatory mechanisms (reviewed in Barron et al., 2006a). However, limited and somewhat mixed data exist regarding the association between endogenous levels of estrogen and cognitive decline (Manly et al., 2000; Schupf et al., 2003). Based on some of our own findings, we here consider the factors that may be useful in predicting memory decline as a risk factor for Alzheimer's disease in older post-menopausal women.


2007 ◽  
Vol 36 (3) ◽  
pp. 149-154 ◽  
Author(s):  
A Taguchi ◽  
M Ohtsuka ◽  
T Nakamoto ◽  
K Naito ◽  
M Tsuda ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document