Abstract 18329: Aortic Pulse Wave Velocity Improves Following Moderate-intensity Continuous Training but not High-intensity Interval Training in Older Men and Postmenopausal Women

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Han-Kyul Kim ◽  
Chueh-Lung Hwang ◽  
Jeung-Ki Yoo ◽  
Moon-Hyon Hwang ◽  
Eileen M Handberg ◽  
...  

Introduction: Aortic pulse wave velocity (AoPWV), a measure of arterial stiffness, increases with age and is an independent predictor of cardiovascular disease. Higher levels of habitual physical activity are associated with reduced AoPWV, but the effect of well-controlled aerobic training interventions in healthy older adults remains unclear. We hypothesized that moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) will both improve AoPWV in healthy older adults. Methods: Thirty five sedentary older men and postmenopausal women, free of overt cardiovascular disease (age, 65±1 yrs, body mass index, 27.7±0.8 kg/m 2 ; systolic and diastolic blood pressures, 116±2 and 69±1 mmHg, respectively; mean±SE) participated in this intervention. Subjects were randomized to MICT (n=13), HIIT (n=12) or non-exercise control group (CONT; n=10). Isocaloric MICT and HIIT were performed on Airdyne bicycles 4 days/week for 8 weeks under supervision. MICT consisted of 47 min of cycling at 70% of maximal heart rate, while HIIT consisted of 40 min of cycling at alternating intensities of 90% and 70% of maximal heart rate. AoPWV, aortic systolic and diastolic blood pressures were evaluated using applanation tonometry (SphygmoCor) before and after the intervention. Results: AoPWV improved by 0.52 m/s in MICT (9.26±0.39 vs. 8.75±0.35 m/s, pre- vs. post-intervention; P<0.05), but did not change in HIIT (9.29±0.29 vs. 9.16±0.38 m/s, P>0.05) or CONT (8.82±0.75 vs. 9.26±0.70 m/s, P>0.05). Aortic systolic blood pressure (MICT: 106±2 vs. 107±3 mmHg; HIIT: 115±3 vs. 113±4 mmHg; CONT: 109±5 vs. 110±4 mmHg) and diastolic blood pressure (MICT: 69±2 vs. 69±2 mmHg; HIIT: 70±2 vs. 70±2 mmHg; CONT: 68±2 vs. 69±2 mmHg) did not change with the intervention (P>0.05). Body mass index remained unchanged in all groups (P>0.05). Conclusions: MICT Airdyne exercise leads to arterial destiffening, however, HIIT does not lead to improved arterial stiffness in healthy older men and postmenopausal women.

2020 ◽  
Vol 28 (6) ◽  
pp. 987-995
Author(s):  
Diana Keyhani ◽  
Bakhtyar Tartibian ◽  
Arezou Dabiri ◽  
Ana Maria Botelho Teixeira

Galectin-3 is a pro-inflammatory biomarker associated with the pathogenesis of heart failure (HF). Physical-activity reduces the risk of heart-failure by modification of inflammation and fibrosis. The purpose of this study was to compare the effects of 8 weeks of high-intensity interval training (HIIT) versus moderate-intensity aerobic continuous training on a predictive factor of HF in postmenopausal women. Thirty sedentary postmenopausal women were randomly assigned to three groups. The first group performed the HIIT program at 60%–90%, and the second group performed an exercise program at 50%–65% of HR reserve. The control group maintained their normal daily regular physical activity level. The gene expressions of galectin-3 and lipid profiles were measured at the baseline and the end of Week 8. The HIIT and moderate-intensity aerobic continuous training attenuated the gene expression of galectin-3, serum low-density lipoprotein, cholesterol, and triglyceride concentrations and enhanced high-density lipoprotein concentrations. These changes were considerably higher in the HIIT group. Our results show that HIIT is superior to moderate-intensity aerobic continuous training in improving the decrease in HF risk in postmenopausal women.


2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Gustavo G. Cardozo ◽  
Ricardo B. Oliveira ◽  
Paulo T. V. Farinatti

Background. We tested the hypothesis that high intensity interval training (HIIT) would be more effective than moderate intensity continuous training (MIT) to improve newly emerged markers of cardiorespiratory fitness in coronary heart disease (CHD) patients, as the relationship between ventilation and carbon dioxide production (VE/VCO2slope), oxygen uptake efficiency slope (OUES), and oxygen pulse (O2P).Methods. Seventy-one patients with optimized treatment were randomly assigned into HIIT (n=23, age = 56 ± 12 years), MIT (n=24, age = 62 ± 12 years), or nonexercise control group (CG) (n=24, age = 64 ± 12 years). MIT performed 30 min of continuous aerobic exercise at 70–75% of maximal heart rate (HRmax), and HIIT performed 30 min sessions split in 2 min alternate bouts at 60%/90% HRmax (3 times/week for 16 weeks).Results. No differences among groups (before versus after) were found for VE/VCO2slope or OUES (P>0.05). After training the O2P slope increased in HIIT (22%,P<0.05) but not in MIT (2%,P>0.05), while decreased in CG (−20%,P<0.05) becoming lower versus HIIT (P=0.03).Conclusion. HIIT was more effective than MIT for improving O2P slope in CHD patients, while VE/VCO2slope and OUES were similarly improved by aerobic training regimens versus controls.


Obesities ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 72-87
Author(s):  
Alexis Marcotte-Chénard ◽  
Dominic Tremblay ◽  
Marie-Michelle Mony ◽  
Pierre Boulay ◽  
Martin Brochu ◽  
...  

Objective: To compare the acute and chronic effects of low-volume high-intensity interval training (HIIT) to moderate-intensity continuous training (MICT) on glycemic control, body composition and continuous glucose monitoring (CGM) in older women with type 2 diabetes (T2D). Methods: Thirty older women (68 ± 5 years) with T2D were randomized in two groups—HIIT (75 min/week) or MICT (150 min/week). Glucose homeostasis (A1c, glucose, insulin, HOMA-IR2) and body composition (iDXA) were measured before and after the 12-week exercise intervention. During the first and last week of training (24-h before and 48-h after exercise), the following CGM-derived data were measured: 24-h and peak glucose levels, glucose variability and time spent in hypoglycemia as well as severe and mild hyperglycemia. Results: While lean body mass increased (p = 0.035), total and trunk fat mass decreased (p ≤ 0.007), without any difference between groups (p ≥ 0.81). Fasting glucose levels (p = 0.001) and A1c (p = 0.014) significantly improved in MICT only, with a significant difference between groups for fasting glucose (p = 0.02). Neither HIIT nor MICT impacted CGM-derived data at week 1 (p ≥ 0.25). However, 24-h and peak glucose levels, as well as time spent in mild hyperglycemia, decreased in HIIT at week 12 (p ≤ 0.03). Conclusion: These results suggest that 12 weeks of low-volume HIIT is enough to provide similar benefit to MICT for body composition and improve the acute effect of exercise when measured with CGM.


Author(s):  
Neumir Sales de Lima ◽  
Ricardo Augusto Leoni De Sousa ◽  
Fabiano Trigueiro Amorim ◽  
Fernando Gripp ◽  
Caíque Olegário Diniz e Magalhães ◽  
...  

Author(s):  
Abdullah Alansare ◽  
Ken Alford ◽  
Sukho Lee ◽  
Tommie Church ◽  
Hyun Jung

Physically inactive adults are prevalent worldwide. This study compared the effects of short-term high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) on heart rate variability (HRV) in physically inactive adults as a preliminary study. Thirteen physically inactive male adults (27.5 ± 3.80 years) were randomly assigned to HIIT (N = 7) or MICT (N = 6). The HIIT program consisted of 20 min of interval training with cycling to rest ratio of 10/50 s at ≥90% HRpeak, while the MICT program consisted of 40 min of continuous cycling at 60–75% HRpeak. Both groups completed eight sessions of training within two weeks. Time and frequency domains of HRV were measured for 20 min with Actiwave-Cardio monitor (CamNtech, UK). The number of R-R interval and inter-beat interval (IBI) were significantly improved (p < 0.05) in both HIIT and MICT programs following eight sessions of training. A significant interaction effect for group by time was found in the lnLF/HF ratio (p < 0.05) where it was only improved in the HIIT group from pre- to post-test. The HIIT program is superior to MICT in improving HRV in physically inactive adults. The HIIT program can be applied as a time-efficient program for improving cardiac-autoregulation.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Lauren E. Skelly ◽  
Celine Bailleul ◽  
Jenna B. Gillen

AbstractInterval training is a form of exercise that involves intermittent bouts of relatively intense effort interspersed with periods of rest or lower-intensity exercise for recovery. Low-volume high-intensity interval training (HIIT) and sprint interval training (SIT) induce physiological and health-related adaptations comparable to traditional moderate-intensity continuous training (MICT) in healthy adults and those with chronic disease despite a lower time commitment. However, most studies within the field have been conducted in men, with a relatively limited number of studies conducted in women cohorts across the lifespan. This review summarizes our understanding of physiological responses to low-volume interval training in women, including those with overweight/obesity or type 2 diabetes, with a focus on cardiorespiratory fitness, glycemic control, and skeletal muscle mitochondrial content. We also describe emerging evidence demonstrating similarities and differences in the adaptive response between women and men. Collectively, HIIT and SIT have consistently been demonstrated to improve cardiorespiratory fitness in women, and most sex-based comparisons demonstrate similar improvements in men and women. However, research examining insulin sensitivity and skeletal muscle mitochondrial responses to HIIT and SIT in women is limited and conflicting, with some evidence of blunted improvements in women relative to men. There is a need for additional research that examines physiological adaptations to low-volume interval training in women across the lifespan, including studies that directly compare responses to MICT, evaluate potential mechanisms, and/or assess the influence of sex on the adaptive response. Future work in this area will strengthen the evidence-base for physical activity recommendations in women.


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