Abstract P032: Feasibility, safety and efficacy of a modified Dietary Approaches to Stop Hypertension diet for Japanese population

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Naoko Miyagawa ◽  
Hisatomi Arima ◽  
Katsushi Yoshita ◽  
Nagako Okuda ◽  
Takayoshi Ohkubo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Pilot Study ◽  
Body Mass ◽  
Dietary Pattern ◽  
Control Diet ◽  
The United States ◽  
Japanese People ◽  
Safety And Efficacy ◽  
Japanese Diet

Introduction: The Dietary Approaches to Stop Hypertension (DASH) eating pattern is widely used for lowering blood pressure in the United States. Food preference and intake volume are quite different among American and Japanese diet; therefore, it is necessary to develop a modified version of DASH dietary pattern for Japanese people (JDASH). Hypothesis: The JDASH is feasible, safe and effective among Japanese people. Methods: This crossover pilot study recruited Japanese men and women aged 30 years and over. Participants were randomized to a three week JDASH diet followed by a three week control diet, or the reverse sequence. Intervention periods were separated by two weeks’ washout in which participants returned to their usual diet. The JDASH dietary pattern consisted of higher potassium, magnesium, calcium, dietary fiber, and n-3 fatty acid and lower sodium than Japanese typical diet. The nutrient balance of the control diet was average Japanese diet based on the National Health and Nutrition Survey in Japan. Primary outcome of this trial was a change in 24 hour urine sodium-to-potassium (Na/K) ratios and secondary outcomes were changes in home and office blood pressure values, lipoprotein profiles and body mass index. These outcomes were from 24 hour urine and blood specimens taken measured before and on the last day of each experimental period. The impact on these measurements was calculated with generalized estimating equation model in consideration of the sequences of intervention. Results: The JDASH diet was well tolerated and with no dropouts. No participant reported any adverse effect regarding this intervention diet and no adverse effects were also observed in biological measures. There were no differences in biological measurements between two diets before intervention. A significant difference in 24 hour urine Na/K ratio was observed (-4.33 mol/mol, p<0.001) between the JDASH diet and the control diet. The differences of systolic blood pressure were - 2.1 mmHg (p=0.396) at the office and -0.1 mmHg (p=0.956) at home, respectively. Significant differences in body mass index and low density lipoprotein were -0.4 kg/m 2 (p=0.002) and -11.0 mg/dl (p=0.038), respectively. Conclusion: Developed modified DASH dietary pattern for Japanese were significantly decrease 24 hour urine Na/K ratio. In conclusion, the results of this pilot study showed the feasibility, safety and efficacy.

Abstract P233: Handgrip Strength Modifies the Association Between Body Mass Index and Blood Pressure in Children and Adolescents of the United States: Experience in NHANES 2011-2014

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Rui Zhang ◽  
Liqiang Zheng ◽  
Wei Chen ◽  
Shengxu Li
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Children And Adolescents ◽  
Body Mass ◽  
Muscular Strength ◽  
Linear Models ◽  
Handgrip Strength ◽  
The United States ◽  
Beneficial Effects ◽  
Unit Increase

Background: Body mass index (BMI), a measure of obesity, is strongly associated with blood pressure (BP) in children and adolescents. Handgrip strength is a measure of muscular strength and body fitness. We hypothesized that handgrip strength modifies the relationship between BMI and BP. Methods: The sample included 3,947 children and adolescents (50.4% boys and 49.6% girls) aged 8-19 years who participated in the National Health and Nutrition Examination Surveys (NHANES) 2011-2014. The sum of the maximum handgrip strength from both hands, standardized to age- and sex-specific z-scores, was used. General linear models were used for data analyses. Results: As expected, BMI was positively correlated with systolic BP (partial correlation coefficient r=0.17, P<0.0001). After adjustment for age, race, sex, and handgrip strength, each BMI unit increase was associated with 0.47 (0.03, standard error) mm Hg increase in systolic BP (P<0.0001). Further, handgrip strength significantly (P=0.0002) attenuated the association between BMI and systolic BP. In those with handgrip strength below the median, each BMI unit increase was associated with 0.59 (0.04) mm Hg increase in systolic BP; such increase was only 0.38 (0.03) mm Hg in those with handgrip strength above the median, representing a 36% reduction in the effect size of BMI on systolic BP. Conclusion: These results suggest that high fitness, measured by handgrip strength, attenuates the adverse effect of obesity on blood pressure levels in children and adolescents, which indicates that increasing muscular strength and body fitness will have beneficial effects on obesity-associated elevated BP in children and adolescents.

2496-PUB: Effect of Body Mass Index on HbA1c, Blood Pressure, and Cholesterol (ABC) Control in Patients with Type 2 Diabetes from Tibet in China

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2496-PUB
Author(s):  
ZHANG CHENGHUI ◽  
LI MINGXIA ◽  
WANG SUYUAN ◽  
WU YUNHONG
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Body Mass

KEJADIAN PENYAKIT HIPERTENSI DAN INDEKS MASSA TUBUH PADA PEREMPUAN YANG TINGGAL DI PEDESAAN DAN PERKOTAAN

2019 ◽  
pp. 127-136
Author(s):  
Venti Agustina
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Rural Women ◽  
Urban Areas ◽  
Stage I ◽  
Normal Body Mass Index ◽  
Cross Sectional ◽  
Normal Body ◽  
Stadium I

Hipertensiadalah penyebab kematian utama di Indonesia. Kematian akibat hipertensi lebih banyak terjadi di perkotaan dibandingkan di desa. Tingginya kejadian hipertensi dipengaruhi oleh faktor yang dapat dikontrol (obesitas,berat badan lebih, konsumsi garam berlebih,aktivitas fisik rendah, perokok, dan konsumsi alkohol) dan faktor yang tidak dapat dikontrol (genetik, usia, dan jenis kelamin). Penelitian bertujuan memberikan gambarandistribusi tekanan darah dan indeks massa tubuh (IMT) pendudukperempuan di kota maupun di desa.Desain penelitian adalah deskriptif kuatitatif dengan pendekatan cross sectional. Data primer didapatkan melalui pengukuran tekanan darah, tinggi badan dan berat badan. Penelitian dilakukan di Desa Kutowinangun Kidul, Kecamatan Tingkir,Salatiga yang mewakili penduduk perempuan di perkotaan dan Desa Batur, Kecamatan Getasan, Kabupaten Semarangyang mewakili penduduk perempuan pedesaan. Adapun jumlah sampel masing-masing 66 respondendan 72responden. Hasil penelitian menunjukkan bahwa kejadian penyakit hipertensi, resiko obese dan obese lebih didominasi oleh respondendi perkotaan dibandingkan di pedesaan dengan rentang usia di atas 46 tahun. Respondendi desa dengan indeks massa tubuh normal cenderung mengalami pre-hipertensi (8,3%) dan hipertensi stadium I (6,9%) sementararesponden dengan resiko obese dan obese cenderung mengalami hipertensi stadium I (1,4%).Respondendi kota dengan indeks massa tubuh normal cenderung mengalami pre hipertensi (6,06%), hipertensi stadium I (4,5%) dan II (7,5%). Responden dengan resiko obese cenderung mengalami hipertensi stadium I (4,5%), dan responden dengan obese I dan II cenderung mengalami pre-hipertensi (4,5%).   Hypertension is the leading cause of death in Indonesia. Deaths due to hypertension are more common in urban areas than in villages. The high incidence of hypertension is influenced by factors that can be controlled (obesity, overweight, excessive salt consumption, low physical activity, smokers, and alcohol consumption) and factors that cannot be controlled (genetic, age, and sex). The study aimed to provide an overview of blood pressure distribution and body mass index (BMI) of female residents in cities and villages. The study design was descriptive quantitative with a cross sectional approach. Primary data was obtained through measurements of blood pressure, height and weight. The study was conducted in Kutowinangun Kidul Village, Tingkir Subdistrict, Salatiga representing women in urban areas and Batur Village, Getasan Subdistrict, Semarang Regency, representing rural women. The number of samples was 66 respondents and 72 respondents respectively. The results showed that the incidence of hypertension, the risk of obese and obese was more dominated by respondents in urban areas than in rural areas with ages above 46 years. Respondents in villages with normal body mass index tended to experience pre-hypertension (8.3%) and stage I hypertension (6.9%) while respondents with obese and obese risk tended to experience stage I hypertension (1.4%). Respondents in cities with normal body mass index tended to experience pre-hypertension (6.06%), stage I hypertension (4.5%) and II (7.5%). Respondents with obese risk tended to experience stage I hypertension (4.5%), and respondents with obese I and II tended to experience pre-hypertension (4.5%).

Effects of Menopause on Trends of Serum Cholesterol, Blood Pressure, and Body Mass Index

Circulation ◽  
1996 ◽  
Vol 94 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Masazumi Akahoshi ◽  
Midori Soda ◽  
Eiji Nakashima ◽  
Katsutaro Shimaoka ◽  
Shinji Seto ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Serum Cholesterol

Association of Body Mass Index With Blood Pressure in Elderly Japanese American Men

Hypertension ◽  
1997 ◽  
Vol 29 (2) ◽  
pp. 673-677 ◽  
Author(s):  
Kamal H. Masaki ◽  
J. David Curb ◽  
Darryl Chiu ◽  
Helen Petrovitch ◽  
Beatriz L. Rodriguez
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Japanese American ◽  
Elderly Japanese

scholarly journals The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aditi Kuber ◽  
Anna Reuter ◽  
Pascal Geldsetzer ◽  
Natsayi Chimbindi ◽  
Mosa Moshabela ◽  
...  
Keyword(s):  
South Africa ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Antiretroviral Therapy ◽  
Body Mass ◽  
Treatment Guidelines ◽  
Causal Effect ◽  
Regression Discontinuity Design ◽  
National Treatment ◽  
Kwazulu Natal

AbstractWe use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART.

Body phenotypes and sexual maturation in Brazilian and US adolescents: evidence for a change in body mass index Category

2020 ◽  
pp. 1-26
Author(s):  
Jéssica Cumpian Silva ◽  
Ana Elisa Madalena Rinaldi ◽  
Francisco de Assis Guedes Vasconcelos ◽  
Maria Alice Altenburg Assis ◽  
Camila Medeiros Mazzeti ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Body Mass ◽  
Phase Angle ◽  
Sexual Maturation ◽  
Biochemical Parameters ◽  
Pubertal Development ◽  
The United States ◽  
Pubic Hair ◽  
Cholesterol Ratio

ABSTRACT Objective: Our study aimed to describe body phenotypes (BP) estimated by multivariate analysis and their association with body mass. Design: Body phenotypes were defined based on demographic variables, anthropometric data (body mass, height, skinfolds and circumferences), body composition (phase angle measured by bioelectrical impedance analysis), biochemical parameters (triglycerides, glucose, total cholesterol ratio/Low Density Lipoproteins (LDL), haemoglobin and sexual maturation (pubic hair and breasts or gonads). Analysis of variance (ANOVA) was performed to verify the differences between skin colour and the stages of pubertal development, body phenotypes, body composition, anthropometric, and biochemical variables. Setting: Cities of São Paulo-SP, Piracicaba-SP and Florianópolis-SC from Brazil and the United States. Participants: 9269 adolescents aged between 10 to 15 years old. Results: The composition of BP was similar in all surveys, which are: BP1 was composed by skinfolds, body mass and circumferences variables; BP2 by pubic hair, breast in girls or gonad in boys, height and age; BP3 by cholesterol, triglycerides and glucose; and BP4 by phase angle, haemoglobin and glucose (negative loading). There was a strong correlation (r = 0.9, p <0.001) between BP1 and body mass index. Conclusion: We highlighted independence observed between biochemical parameters, anthropometry, body composition and sexual maturation. BP may support the calculation of scores for diagnosis of obesity based on anthropometric variables and overcome ambiguity in the isolated use of body mass index.

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