Abstract 409: The Association Between Carotid Artery Plaqus and Cardiovascula Risk Factor in Japanese Individuals

Hypertension ◽  
2013 ◽  
Vol 62 (suppl_1) ◽  
Author(s):  
Mikio Arita ◽  
Hiroto Tanaka ◽  
Maasa Takahashi ◽  
Shiori Nagano ◽  
Keiko Sasabe ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Health Examination ◽  
High Tendency ◽  
Comprehensive Health ◽  
Sodium Ingestion

Introduction: Patients with many cardiovascular risk factors develop the carotid artery plaques(CAP) at the early atherosclerotic change. In this study, we performed the comparison between the individuals with CAP and without CAP and investigated the characteristics of cardiovascular risk factors. Subjects and methods: A total of 310 individuals matched-age(mean age 67.6± 3.7 years) underwent the comprehensive health examination such as Body mass index(BMI), AIP75, blood pressure(BP), Sodium ingestion, Pulse wave velocity(PWV) and serum data. Carotid artery ultrasound was done to all individuals and CAP and the intima-media thickness(IMT) were shown. Results: The prevalence of CAP was 20%(62/310) and that of CAP in men and women was 24.6%(35/142) and 16.1%(27/168), respectively. PWV and IMT of the individuals with CAP (CAP group) was significantly higher, compared with those without CAP (not CAP group). BMI and sodium ingestion of CAP group was significantly lower, compared with those of not CAP group. In addition, systolic BP and G-GTP of CAP group showed the high tendency (p=0.085, p=0.056, respectively) and diastolic BP and HDL-C of CAP group showed the low tendency (p=0.097, p=0.052, respectively), compared with those of not CAP group. PWV of CAP group in man was significantly higher, compared with that of not CAP group in man. However, HDL-C of CAP group in woman showed the low tendency, compared with that of that of not CAP group in woman. Conclusion: It has been suggested that the development of CAP is associated with the cardiovascular risk factor such as PWV, IMT, HDL-C , G-GTP and BP.

The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness: A Randomized Trial

2007 ◽  
Vol 21 (6) ◽  
pp. 510-516 ◽  
Author(s):  
Steven G. Aldana ◽  
Roger Greenlaw ◽  
Audrey Salberg ◽  
Ray M. Merrill ◽  
Ron Hager ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiac Rehabilitation ◽  
Cardiovascular Risk Factors ◽  
Dietary Habits ◽  
Intima Media Thickness ◽  
Media Thickness ◽  
Number Of Patients

Purpose. This study evaluated the effect of the Dr. Dean Ornish Program for Reversing Heart Disease on cardiovascular disease as measured by the intima-media thickness of the common carotid artery and compared this effect to outcomes from patients participating in traditional cardiac rehabilitation. Design. Randomized clinical trial. Setting. SwedishAmerican Health System. Subjects. Ninety three patients with clinically confirmed coronary artery disease were randomly assigned to the intervention (n = 46) or traditional cardiac rehabilitation (n = 47). Intervention. Dr. Dean Ornish Program for Reversing Heart Disease. Measures. Ultrasound of the carotid artery and other cardiovascular risk factors were measured at baseline, 6, and 12 months. Analysis. Intent-to-treat analysis. Results. There was no significant reduction in the carotid intima-media thickness of the carotid artery in the Ornish group or the cardiac rehabilitation group. Ornish Program participants had significantly improved dietary habits (p < .001), weight (p < .001), and body mass index (p < .001) as compared with the rehabilitation group. The decrease in the number of patients with angina from baseline to 12 months was 44% in Ornish and 12% in cardiac rehabilitation. Conclusions. The Ornish Program appears to causes improvements in cardiovascular risk factors but does not appear to change the atherosclerotic process as it affects the carotid artery.

Association Between Carotid Artery Intima-Media Thickness and Cardiovascular Risk Factors in CKD

2005 ◽  
Vol 46 (5) ◽  
pp. 856-862 ◽  
Author(s):  
Emma Preston ◽  
Mary R. Ellis ◽  
Elena Kulinskaya ◽  
Alun H. Davies ◽  
Edwina A. Brown
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Media Thickness

scholarly journals Sex modifies the association between body mass index and carotid artery intima media thickness in the multi-ethnic Singapore population

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
R Dalan ◽  
T Mina ◽  
N A Nur Azizah ◽  
T Tong ◽  
M Loh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Cvd Risk ◽  
Media Thickness ◽  
Healthy Participants

Abstract Background and aims Globally cardiovascular disease (CVD) risk is higher in men than in women in the younger age group but the risk is attenuated in later life with an unexpected higher risk in women in some populations. A better understanding of sex differences in CVD is needed. Carotid artery intima-media thickness (CIMT) has been proposed for CVD risk assessment in individuals at intermediate risk. We study the gender interactions in the associations of the traditional cardiovascular risk factors with CIMT. Methods We performed carotid ultrasonography in the large population health study-HELIOS conducted in Singapore. Measurements were performed as per Mannheim consensus, at the far wall of bilateral common carotid artery at 8 sites in each participant. We report the average of all measurements (avgCIMT) and maximum value (maxCIMT). We analysed 2061 healthy participants recruited between 2018–2020. Inclusion criteria for this analysis: non-smokers, not known to have diabetes, hypertension, hyperlipidemia or ischemic heart disease. Individuals with systolic blood pressure &gt;160 mm Hg or fasting glucose &gt;7.0 mmol/L on recruitment were excluded. Multivariable linear regression analysis was performed to examine the association between CIMT and cardiovascular risk factors in the healthy population adjusting for age, sex and ethnicity. All analysis was performed using Stata version 16.0. Results After exclusion, 1407 healthy participants were included in the analysis. Median (IQR) avgCIMT: 0.56 (0.50, 0.65) in men; 0.54 (0.50, 0.58) in women. Median (IQR) maxCIMT: 0.64 (0.57, 0.76) in men; 0.61 (0.54, 0.70) in women. The avgCIMT and the maxCIMT were higher in males when compared to women and all traditional cardiovascular risk factors associated with CIMT after adjustment for age, sex and ethnicity (P&lt;0.05) (Table 1). Interaction tests in multivariable model adjusted for age, ethnicity, pulse pressure, non HDL-C and HbA1c showed a significant interaction between sex and body mass index (BMI) with predicted effects on avgCIMT and maxCIMT being relatively higher in males at the same BMI when compared to females (P-interaction &lt;0.01) (Figure 1). Conclusion Sex modifies the relationship between BMI and CIMT in Singapore's multi-ethnic population. Understanding the intermediary mechanisms involved will help in developing personalized preventive strategies. FUNDunding Acknowledgement Type of funding sources: None. Figure 1

scholarly journals Cardiovascular Risk Factors in Childhood and Carotid Artery Intima-Media Thickness in Adulthood

JAMA ◽  
2003 ◽  
Vol 290 (17) ◽  
pp. 2277 ◽  
Author(s):  
Olli T. Raitakari ◽  
Markus Juonala ◽  
Mika Kähönen ◽  
Leena Taittonen ◽  
Tomi Laitinen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Media Thickness
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