scholarly journals Exploring Opportunities for Primary Prevention of Unprovoked Venous Thromboembolism: Ready for Prime Time?

2020 ◽  
Vol 9 (23) ◽  
Author(s):  
Aaron R. Folsom ◽  
Mary Cushman
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Venous Thromboembolism ◽  
Primary Prevention ◽  
Physical Inactivity ◽  
The United States ◽  
Considerable Proportion ◽  
Current Smoking ◽  
Lifestyle Risk Factors ◽  
Lifestyle Risk

Abstract Venous thromboembolism (VTE) is an important vascular disease and public health problem. Prevention of VTE has focused mainly on using thromboprophylaxis to avoid provoked VTE or recurrent VTE, with little attention paid to the possibility of preventing the one third to one half of VTEs that are unprovoked. We review growing research suggesting that unhealthy lifestyle risk factors may cause a considerable proportion of unprovoked VTE. Using epidemiologic data to calculate population attributable risks, we estimate that in the United States obesity may contribute to 30% of VTEs, physical inactivity to 4%, current smoking to 3%, and Western dietary pattern to 11%. We also review possibilities for VTE primary prevention either through a high‐risk individual approach or a population‐wide approach. Interventions for outpatients at high VTE risk but without VTE provoking factors have not been fully tested; yet, improving patient awareness of risk and symptoms, lifestyle counseling, and possibly statins or direct oral anticoagulants may prove useful in primary prevention of unprovoked VTE. A population approach to prevention would bolster awareness of VTE and aim to shift lifestyle risk factors downward in the whole population using education, environmental changes, and policy. Assuming the epidemiological associations are accurate, causal, and independent of each other, a reduction of obesity, physical inactivity, current smoking, and Western diet by 25% in the general population might reduce the incidence of unprovoked VTE by 12%. We urge further research and consideration that primary prevention of unprovoked VTE may be a worthwhile public health aim.

Beyond Blood Pressure Screening: A Rationale for Promoting the Primary Prevention of Hypertension

1988 ◽  
Vol 3 (2) ◽  
pp. 5-11 ◽  
Author(s):  
Christopher L. Melby ◽  
Roseann M. Lyle ◽  
Gerald C. Hyner
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Primary Prevention ◽  
Scientific Evidence ◽  
Public Health Problem ◽  
The United States ◽  
Major Public Health Problem ◽  
Lifestyle Risk Factors ◽  
Lifestyle Risk ◽  
Prevention Of Hypertension

High blood pressure is a major public health problem in the United States. However, the underlying reasons for the chronic elevation of blood pressure (BP) are unknown in most cases of hypertension (HT), and medical care has focused on lowering already elevated BP, primarily by pharmacologic means. Although an important factor in the development of HT appears to be a genetic predisposition, other potentially modifiable lifestyle risk factors associated with elevated BP have been identified. This article describes the scientific rationale for encouraging health promotion specialists to focus on the primary prevention of abnormally elevated blood pressure. Nonbehavioral risk factors such as increasing age, history of HT, Black ancestry, and consistent BP readings in the higher range of normality, and behavioral factors including dietary excesses and deficiencies, excessive body fat, a sedentary life style, and frequent episodes of unmanageable emotional stress are addressed. Recommendations are made based on scientific evidence supporting the relationships between these risk factors and the development of HT.

Common risk factors of breast and ovarian cancer: recent view

2004 ◽  
Vol 14 (5) ◽  
pp. 721-740 ◽  
Author(s):  
G. C. Zografos ◽  
M. Panou ◽  
N. Panou
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Ovarian Cancer ◽  
Gynecological Cancer ◽  
Breast And Ovarian Cancer ◽  
Lifestyle Risk Factors ◽  
Cancer Types ◽  
Common Risk Factors ◽  
The Common ◽  
Lifestyle Risk

Clinicians, epidemiologists, and public health specialists tend to examine breast and ovarian cancer separately. Although this seems fairly rational and expected, both malignancies are estrogen related and thus share many risk factors. In this review, we investigate the common familial, reproductive, anthropometric, nutritional, and lifestyle risk factors of breast and ovarian cancer. We believe that the parallel examination of the two cancer types could significantly contribute to an improved prevention of “gynecological cancer” as a whole.

scholarly journals Lifestyle Risk Factors and All-Cause and Cardiovascular Disease Mortality: Data from the Korean Longitudinal Study of Aging

2019 ◽  
Vol 16 (17) ◽  
pp. 3040 ◽  
Author(s):  
Inhwan Lee ◽  
Shinuk Kim ◽  
Hyunsik Kang
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Risk Factor ◽  
Physical Inactivity ◽  
Mortality Data ◽  
Lifestyle Risk Factors ◽  
Disease Mortality ◽  
Increased Risk ◽  
Lifestyle Risk ◽  
Cvd Mortality

This study examined the association between lifestyle risk factors and all-cause and cardiovascular disease (CVD) mortality in 9945 Korea adults (56% women) aged 45 years and older. Smoking, heavy alcohol intake, underweight or obesity, physical inactivity, and unintentional weight loss (UWL) were included as risk factors. During 9.6 ± 2.0 years of follow-up, there were a total of 1530 cases of death from all causes, of which 365 cases were from CVD. Compared to a zero risk factor (hazard ratio, HR = 1), the crude HR of all-cause mortality was 1.864 (95% CI, 1.509–2.303) for one risk factor, 2.487 (95% confidence interval, CI, 2.013–3.072) for two risk factors, and 3.524 (95% CI, 2.803–4.432) for three or more risk factors. Compared to a zero risk factor (HR = 1), the crude HR of CVD mortality was 2.566 (95% CI, 1.550–4.250) for one risk factor, 3.655 (95% CI, 2.211–6.043) for two risk factor, and 5.416 (95% CI, 3.185–9.208) for three or more risk factors. The HRs for all-cause and CVD mortality remained significant even after adjustments for measured covariates. The current findings showed that five lifestyle risk factors, including smoking, at-risk alcohol consumption, underweight/obesity, physical inactivity, and UWL, were significantly associated with an increased risk of all-cause and CVD mortality in Korean adults.

scholarly journals Lifestyle Risk Factors for Type 2 Diabetes Mellitus and National Diabetes Care Systems in European Countries

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2806
Author(s):  
Emma Altobelli ◽  
Paolo Matteo Angeletti ◽  
Valerio F. Profeta ◽  
Reimondo Petrocelli
Keyword(s):  
Risk Factors ◽  
Prevalence Rate ◽  
Physical Inactivity ◽  
Multiple Correspondence Analysis ◽  
Health Planning ◽  
Prevalence Rates ◽  
Eu Countries ◽  
Lifestyle Risk Factors ◽  
Lifestyle Risk

Background. Diabetes is increasing by 3.09% per year in males and 1.92% in females. Lifestyle risk factors are related to diabetes. The aim of this work is to highlight within EU-28 countries the distribution percentages of some lifestyle risk factors and some components of diabetes health care. Methods. A literature search was conducted to highlight the presence of diabetes registries, which are fundamental tools for disease surveillance and health planning; the presence of a national diabetes plan (NDP); the care setting; and methods used for reimbursement of drugs, devices, and coverage of any comorbidities associated with diabetes. A multiple correspondence analysis (MCA) was carried out to evaluate the possible associations between the variables considered. Results. The highest percentages of diabetes (>10%) are registered in Bulgaria, Malta, and Hungary. Concerning the prevalence of overweight, no European country shows overall percentages of less than 50%. Regarding obesity, 57% of countries show prevalence rates of 25%. The record for physical inactivity belongs to Malta, with 45% of individuals being inactive. The percentage of physical inactivity for females is higher than for males across Europe. In total, 57% of the countries have an insurance-based health system, while 12 countries have public national health systems. Further, 57% of countries have an NDP, while 42% of the EU countries have established a prevalence register for diabetes. Conclusions. Prevalence rates for type 2 DM in the range of 8–9% are noted in 50% of EU-28 countries. In total, 21 out of EU countries show a high prevalence rate for overweight, while 7% of EU-28 countries have an obesity prevalence rate of 25%. Diabetes treatment is entrusted to general practitioners in most countries. The results of this work highlight the differences between countries, but also between genders.

scholarly journals Modifiable Cardiovascular Disease Risk Factors among Indigenous Populations

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Adam A. Lucero ◽  
Danielle M. Lambrick ◽  
James A. Faulkner ◽  
Simon Fryer ◽  
Michael A. Tarrant ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
American Indians ◽  
The United States ◽  
Alaska Natives ◽  
Indigenous Populations ◽  
Aboriginal Australians ◽  
Lifestyle Risk Factors ◽  
Indigenous Groups ◽  
Lifestyle Risk

Objective. To identify modifiable cardio-metabolic and lifestyle risk factors among indigenous populations from Australia (Aboriginal Australians/Torres Strait Islanders), New Zealand (Māori), and the United States (American Indians and Alaska Natives) that contribute to cardiovascular disease (CVD).Methods. National health surveys were identified where available. Electronic databases identified sources for filling missing data. The most relevant data were identified, organized, and synthesized.Results. Compared to their non-indigenous counterparts, indigenous populations exhibit lower life expectancies and a greater prevalence of CVD. All indigenous populations have higher rates of obesity and diabetes, hypertension is greater for Māori and Aboriginal Australians, and high cholesterol is greater only among American Indians/Alaska Natives. In turn, all indigenous groups exhibit higher rates of smoking and dangerous alcohol behaviour as well as consuming less fruits and vegetables. Aboriginal Australians and American Indians/Alaska Natives also exhibit greater rates of sedentary behaviour.Conclusion. Indigenous groups from Australia, New Zealand, and the United States have a lower life expectancy then their respective non-indigenous counterparts. A higher prevalence of CVD is a major driving force behind this discrepancy. A cluster of modifiable cardio-metabolic risk factors precede CVD, which, in turn, is linked to modifiable lifestyle risk factors.

scholarly journals Dietary and Lifestyle Risk Factors and Metabolic Syndrome: Literature Review

2018 ◽  
Vol 6 (3) ◽  
pp. 594-608 ◽  
Author(s):  
RAWAN H. AL-QAWASMEH ◽  
REEMA F. TAYYEM
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Positive Family History ◽  
Lifestyle Changes ◽  
Abdominal Adiposity ◽  
Metabolic Abnormalities ◽  
Lifestyle Risk Factors ◽  
History Of ◽  
Lifestyle Risk

Metabolic syndrome (MetS) is considered a threat to public health due to its rapid growing prevalence worldwide. MetS can result from interrelated metabolic abnormalities including insulin resistance (IR), hypertension, dyslipidemia, and abdominal adiposity. Although the pathogenesis of this syndrome is not distinctly understood, it is strongly influenced by multiple genetic variations that interact with many environmental factors such as positive family history of MetS, adherence to unhealthy dietary patterns, low physical activity and smoking and that explain the variations in the prevalence of the MetS within and across populations. All of these factors were found to be associated with IR, obesity, and triglycerides elevation which therefore increase the risk of the MetS Several studies highlighted the effective preventive approach includes lifestyle changes, primarily losing weight, adopting healthy diet, and practicing exercise. All of the mentioned factors can reduce the risk of MetS.

Physical inactivity and other chronic disease-related lifestyle risk factors in a sample of Canadian youth

2010 ◽  
Vol 12 ◽  
pp. e63
Author(s):  
R. Plotnikoff ◽  
N. Karunamuni ◽  
J. Spence ◽  
K. Storey ◽  
L. Forbes ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Disease ◽  
Physical Inactivity ◽  
Lifestyle Risk Factors ◽  
Canadian Youth ◽  
Lifestyle Risk
Sign in / Sign up

Export Citation Format

Share Document