Abstract WP418: A Systematic Comparison of Key Features of Ischaemic Stroke Prevention Guidelines in Low- and Middle-income vs High-income Countries

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Hernan O Bayona ◽  
Mayowa Owolabi ◽  
Wayne Feng ◽  
James R Sawers ◽  
Paul Olowoyo ◽  
...  
Keyword(s):  
Stroke Prevention ◽  
High Income ◽  
Evidence Based ◽  
Vascular Risk ◽  
Eligibility Criteria ◽  
Middle Income ◽  
Middle Income Countries ◽  
Prevention Guideline ◽  
Prevention Guidelines ◽  
Low And Middle Income

Introduction: Implementation of contextually appropriate, evidence-based, expert-recommended stroke prevention guideline is particularly important in Low- and Middle-Income Countries (LMICs), which bear disproportional larger burden of stroke while possessing fewer resources. Focus therefore, should be on approaches enabling healthcare systems to improve control of vascular risk factors. Objective: We aimed to compare important features of stroke prevention guidelines between LMICs and High Income Countries (HICs). Methods: We systematically searched PubMed, AJOL, SciELO, and LILACS databases for stroke prevention guidelines published between January 2005 and December 2015 by country. Primary search items included: “Stroke” and “Guidelines”. We critically appraised the articles for evidence level, issuance frequency and implementation aspects to clinical practice. Results: Among 45 stroke prevention guidelines published, 28 (62%) met eligibility criteria: 7 from LMICs (25%) and 21 from HICs (75%). LMIC-issued guidelines were less likely to have conflict of interest declarations (57% vs. 100%, p=0.01), involve high quality systematic reviews (57% vs. 95%, p= 0.03), had good dissemination channels (14% vs 71%, p=0.02). The patient views and preferences were the most significant stakeholder considerations in HICs (43%, p=0.04) compared with LMICs. Conclusion: The quality and quantity of stroke prevention guidelines in LMICs are less than those of HICs and need to be significantly improved upon.

Abstract P681: Implementation of Stroke Prevention Interventions in Low- and Middle-Income Countries: A Scoping Review

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Nessa Ryan ◽  
Vida Rebello ◽  
Desiree Gutierrez ◽  
Kameko Washburn ◽  
Alvaro Zevallos Barboza ◽  
...  
Keyword(s):  
Scoping Review ◽  
Stroke Prevention ◽  
Health Workers ◽  
Evidence Based ◽  
Community Based Interventions ◽  
Middle Income ◽  
Middle Income Countries ◽  
Implementation Outcomes ◽  
Prevention Interventions ◽  
Low And Middle Income

Background: Stroke is the second leading cause of death globally and an increasing concern in low- and middle-income countries (LMIC) where, due to limited capacity to treat stroke, preventative efforts are critically important. Although some research on evidence-based interventions for stroke prevention in LMIC exists, there remains a significant gap in understanding of their implementation across various contexts in LMIC. Objectives: In this scoping review, our objective was to identify and synthesize the implementation outcomes (using Proctor et al.’s taxonomy, 2011) for stroke prevention interventions, as well as to describe the diverse interventions employed. Methods: Eligible studies were empirical, focused on implementation of stroke prevention programs or policies, and occurred in at least one LMIC. Five databases were searched, including PubMed, PsycINFO, CINAHL, EMBASE, and Web of Science. Two reviewers independently assessed studies for selection and charted data; discrepancies were resolved through discussion with a third reviewer until consensus was reached. Narrative synthesis was used to analyze and interpret the findings. Results: Studies were predominantly focused in Asia, targeting primary or secondary prevention, and facility-based. Interventions were conducted at the level of individual (n=11), system (n=12), or both (n=4). Various implementation outcomes were reported, most commonly cost (n=10), acceptability (n=7), fidelity (n=7), and feasibility (n=6), but also adoption (n=4), penetration (n=3), appropriateness (n=1), and sustainability (n=1). Conclusions: Findings highlight the breadth of evidence-based interventions for stroke prevention available to implement in LMIC settings, including culturally acceptable education interventions, cost-effective medications, and community-based interventions implemented by community health workers. Implementation outcomes remain under-reported, and more rigorous research is needed to better plan and evaluate the implementation of these interventions to prevent stroke.

Abstract P723: Adaptation of Stroke Prevention Interventions for Low- and Middle-Income Countries: A Scoping Review

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Nessa Ryan ◽  
Kameko Washburn ◽  
Vida Rebello ◽  
Desiree Gutierrez ◽  
Hector Perez ◽  
...  
Keyword(s):  
Scoping Review ◽  
Stroke Prevention ◽  
Health Workers ◽  
Evidence Based ◽  
Two Phase ◽  
Middle Income ◽  
Risk Factor Modification ◽  
Middle Income Countries ◽  
Prevention Interventions ◽  
Low And Middle Income

Introduction: Stroke is a leading cause of mortality globally, with 85% of stroke death occurring in low- and middle-income countries (LMICs). Translation of evidence-based stroke prevention interventions from their original setting to the novel context in which they will be implemented is often unreported; especially in LMICs where it has been severely understudied. Thus, our objective was to investigate how adaptation has been examined within research on stroke prevention interventions in LMICs through a scoping review of the available literature in order to highlight benefits and best-practices, identify gaps, and develop a greater understanding of these efforts that will ultimately support attempts to address the global burden of stroke. Methods: This review was conducted in accordance with PRISMA-ScR guidelines. Five databases were searched (PubMed, PsycINFO, CINAHL, EMBASE, and Web of Science), for eligible studies using a search strategy developed in consultation with a research librarian. Two reviewers independently assessed the retrieved articles for selection based on the inclusion criteria (peer-reviewed empirical papers or protocols, reported on adaptation of stroke prevention interventions, and occurred in at least one LMIC) through a two phase process consisting of (1) title and abstract screening and (2) full-text screening. Discrepancies were resolved through discussion until consensus was reached. Data were charted and a narrative synthesis, guided by the FRAME framework, was used to analyze and interpret the findings. Results: Of 380 articles retrieved, a total of six articles reporting adaptation of primary (n=4) or secondary (n=2) stroke prevention interventions in LMICs were identified. Types of interventions included use of community health workers (n = 2), use of mHealth tools (n=2), and interventions aimed at risk factor modification (n = 2). Adaptations were proactively planned, with multiple adaptation goals reported. Conclusions: This is the first review of its kind to focus on adaptation of evidence-based stroke prevention interventions in LMICs. Through our systematic investigation, we highlight the need for additional research to assess the processes and outcomes of stroke prevention interventions.

scholarly journals Breast Cancer Patient Advocacy: Challenges and Opportunities in Low- and Middle-Income Countries

2020 ◽  
Vol 6 (Supplement_1) ◽  
pp. 39-39
Author(s):  
Allison Dvaladze ◽  
Darya A. Kizub ◽  
Anna Cabanes ◽  
Gertrude Nakigudde ◽  
Bertha Aguilar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Patient Advocacy ◽  
High Income ◽  
Civil Society Organizations ◽  
Evidence Based ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

PURPOSE Breast cancer advocacy movements, driven by advocate-led civil society organizations (CSOs), have proven to be a powerful force for the advancement of cancer control in high-income countries, playing a critical role in providing peer support, raising awareness, reducing stigma, educating the public, raising funds, influencing policy, and affecting national cancer research agendas by bringing the public’s concerns about cancer to policymakers and the medical community. Breast cancer patient advocacy movements are growing in low- and middle-income countries (LMICs) in response to an increasing cancer burden and disparities in outcomes; however, there are few studies on the experiences and needs of advocate-led breast cancer CSOs in LMICs. METHODS We conducted a qualitative study using in-depth interviews and focus group discussions with 98 participants representing 23 LMICs in Eastern Europe, Central Asia, East and Southern Africa, and Latin America. RESULTS Despite geographic, cultural, and socioeconomic differences, the common themes that emerged across the 3 regions are strikingly similar: trust, knowledge gaps, stigma, sharing experiences, and sustainability. We identified common facilitators—training/education, relationship building/networking, third-party facilitators, communication—and barriers—mistrust, stigma, organizational fragility, difficulty translating high-income country strategies—to establishing trust, collaboration, and advancing cancer advocacy efforts. To our knowledge, our study is the first to describe the role coalitions and regional networks play in advancing breast cancer advocacy in LMICs across multiple regions CONCLUSION Our findings reflect the importance of investing in three-way partnerships between CSOs, political leaders, and health experts. When provided with information that is evidence based and relevant to their respective environments, as well as opportunities to engage and network, advocates are better equipped to pursue evidence-based programs, advocate for appropriate solutions, and to hold their governments accountable to the commitments they make. Global and local actors can do more to create opportunities for education and engagement.

scholarly journals Atrial fibrillation in low- and middle-income countries: a narrative review

2020 ◽  
Vol 22 (Supplement_O) ◽  
pp. O61-O77
Author(s):  
Itamar S Santos ◽  
Alessandra C Goulart ◽  
Rodrigo D Olmos ◽  
G Neil Thomas ◽  
Gregory Y H Lip ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Health Outcomes ◽  
Economic Burden ◽  
Stroke Prevention ◽  
Public Health Problem ◽  
High Income ◽  
Narrative Review ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

Abstract Preventing premature non-communicable disease mortality necessitates a thorough review of one of the most important risk factors for stroke, which is atrial fibrillation (AF). The latter and AF-related stroke are still considered to be problems of high-income countries and are frequently overlooked in low- and middle-income countries (LMICs). In this narrative review, we provide an overview of studies that evaluated at least one of the following determinants of AF burden in LMICs: current epidemiology and trends, stroke prevention, health outcomes, and economic burden. Studies focusing on samples close to the general population (including community- and primary care-based samples) indicate sex-specific prevalence rates up to 7.4% in LMICs. Although AF prevalence is still higher in high-income countries than LMICs, the gap in AF burden between these two groups has been reducing in the past three decades. Oral anticoagulant (OAC) therapy for stroke prevention is underused in LMICs, and there are little data on OAC therapy in relation to stroke risk scores, such as CHA2DS2-VASc. Available data also points to higher morbidity and mortality for patient with AF in LMICs than their counterparts in high-income countries. Data on the consequent economic burden in LMICs is scarce, but it is reasonable to consider it will follow the same trend as that observed for health outcomes. Raising the visibility of AF as a public health problem in LMICs is necessary as a first step to providing adequate care for patients with this condition.

scholarly journals Adherence to Food-Based Dietary Guidelines: A Systemic Review of High-Income and Low- and Middle-Income Countries

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 1038
Author(s):  
Ana Carolina B. Leme ◽  
Sophia Hou ◽  
Regina Mara Fisberg ◽  
Mauro Fisberg ◽  
Jess Haines
Keyword(s):  
English Language ◽  
Economic Status ◽  
High Income ◽  
Dietary Guidelines ◽  
Systemic Review ◽  
Healthy Children ◽  
Future Health ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

Research comparing the adherence to food-based dietary guidelines (FBDGs) across countries with different socio-economic status is lacking, which may be a concern for developing nutrition policies. The aim was to report on the adherence to FBDGs in high-income (HIC) and low-and-middle-income countries (LMIC). A systematic review with searches in six databases was performed up to June 2020. English language articles were included if they investigated a population of healthy children and adults (7–65 years), using an observational or experimental design evaluating adherence to national FBDGs. Findings indicate that almost 40% of populations in both HIC and LMIC do not adhere to their national FBDGs. Fruit and vegetables (FV) were most adhered to and the prevalence of adhering FV guidelines was between 7% to 67.3%. HIC have higher consumption of discretionary foods, while results were mixed for LMIC. Grains and dairy were consumed below recommendations in both HIC and LMIC. Consumption of animal proteins (>30%), particularly red meat, exceeded the recommendations. Individuals from HIC and LMIC may be falling short of at least one dietary recommendation from their country’s guidelines. Future health policies, behavioral-change strategies, and dietary guidelines may consider these results in their development.

scholarly journals Evidence-Based Guidelines for Mental, Neurological, and Substance Use Disorders in Low- and Middle-Income Countries: Summary of WHO Recommendations

PLoS Medicine ◽  
2011 ◽  
Vol 8 (11) ◽  
pp. e1001122 ◽  
Author(s):  
Tarun Dua ◽  
Corrado Barbui ◽  
Nicolas Clark ◽  
Alexandra Fleischmann ◽  
Vladimir Poznyak ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Evidence Based ◽  
Middle Income ◽  
Middle Income Countries ◽  
Evidence Based Guidelines ◽  
Low And Middle Income

scholarly journals Effective Strategies for Global Health Training Programs A Systematic Review of Training Outcomes in Low and Middle Income Countries

2016 ◽  
Vol 8 (11) ◽  
pp. 278 ◽  
Author(s):  
Aprill Z. Dawson ◽  
Rebekah J. Walker ◽  
Jennifer A. Campbell ◽  
Leonard E. Egede
Keyword(s):  
Medical Training ◽  
Skills Training ◽  
High Income ◽  
Training Methods ◽  
Middle Income ◽  
Training Outcomes ◽  
Effective Strategies ◽  
Middle Income Countries ◽  
Low Middle Income Countries ◽  
Low And Middle Income

<p><strong>INTRODUCTION: </strong>Low and middle-income countries face a continued burden of chronic illness and non-communicable diseases while continuing to show very low health worker utilization. With limited numbers of medical schools and a workforce shortage the poor health outcomes seen in many low and middle income countries are compounded by a lack of within country medical training.</p><p><strong>METHODS: </strong>Using a systematic approach, this paper reviews the existing literature on training outcomes in low and middle-income countries in order to identify effective strategies for implementation in the developing world. This review examined training provided by high-income countries to low- and middle-income countries.</p><p><strong>RESULTS: </strong>Based on article eligibility, 24 articles were found to meet criteria. Training methods found include workshops, e-learning modules, hands-on skills training, group discussion, video sessions, and role-plays. Of the studies with statistically significant results training times varied from one day to three years. Studies using both face-to-face and video found statistically significant results.</p><p><strong>DISCUSSION:</strong> Based on the results of this review, health professionals from high-income countries should be encouraged to travel to low- middle-income countries to assist with providing training to health providers in those countries.</p>

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