scholarly journals A morphospace of functional configuration to assess configural breadth based on brain functional networks

2021 ◽  
pp. 1-36
Author(s):  
Duy Duong-Tran ◽  
Abbas Kausar ◽  
Enrico Amico ◽  
Bernat Corominas-Murtra ◽  
Mario Dzemidzic ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Fluid Intelligence ◽  
Mental States ◽  
Trapping Efficiency ◽  
Functional Networks ◽  
Behavioral Measures ◽  
The Brain ◽  
2D Network ◽  
Different Levels ◽  
Do So

Abstract The quantification of human brain functional (re-)configurations across varying cognitive demands remains an unresolved topic. We propose that such functional configurations may be categorized into three different types: i) Network Configural Breadth, ii) Task-to Task transitional reconfiguration, and iii) Within-Task reconfiguration. Such functional reconfigurations are rather subtle at the whole-brain level. Hence, we propose a mesoscopic framework focused on functional networks (FNs) or communities to quantify functional (re-)configurations. To do so, we introduce a 2D network morphospace that relies on two novel mesoscopic metrics, Trapping Efficiency (TE) and Exit Entropy (EE), which capture topology and integration of information within and between a reference set of FNs. We use this framework to quantify the Network Configural Breadth across different tasks. We show that the metrics defining this morphospace can differentiate FNs, cognitive tasks and subjects. We also show that network configural breadth significantly predicts behavioral measures, such as episodic memory, verbal episodic memory, fluid intelligence and general intelligence. In essence, we put forth a framework to explore the cognitive space in a comprehensive manner, for each individual separately, and at different levels of granularity. This tool that can also quantify the FN-reconfigurations that result from the brain switching between mental states.

scholarly journals A Neuroscience Levels of Explanation Approach to the Mind and the Brain

2021 ◽  
Vol 15 ◽  
Author(s):  
Edmund T. Rolls
Keyword(s):  
Mental States ◽  
Levels Of Explanation ◽  
Processing Level ◽  
Reductive Physicalism ◽  
Brain States ◽  
High Level ◽  
The Mind ◽  
Mental Events ◽  
The Brain ◽  
Different Levels

The relation between mental states and brain states is important in computational neuroscience, and in psychiatry in which interventions with medication are made on brain states to alter mental states. The relation between the brain and the mind has puzzled philosophers for centuries. Here a neuroscience approach is proposed in which events at the sub-neuronal, neuronal, and neuronal network levels take place simultaneously to perform a computation that can be described at a high level as a mental state, with content about the world. It is argued that as the processes at the different levels of explanation take place at the same time, they are linked by a non-causal supervenient relationship: causality can best be described in brains as operating within but not between levels. This allows the supervenient (e.g., mental) properties to be emergent, though once understood at the mechanistic levels they may seem less emergent, and expected. This mind-brain theory allows mental events to be different in kind from the mechanistic events that underlie them; but does not lead one to argue that mental events cause brain events, or vice versa: they are different levels of explanation of the operation of the computational system. This approach may provide a way of thinking about brains and minds that is different from dualism and from reductive physicalism, and which is rooted in the computational processes that are fundamental to understanding brain and mental events, and that mean that the mental and mechanistic levels are linked by the computational process being performed. Explanations at the different levels of operation may be useful in different ways. For example, if we wish to understand how arithmetic is performed in the brain, description at the mental level of the algorithm being computed will be useful. But if the brain operates to result in mental disorders, then understanding the mechanism at the neural processing level may be more useful, in for example, the treatment of psychiatric disorders.

Functional networks of the brain: from connectivity restoration to dynamic integration

2020 ◽  
Author(s):  
Aleksandr E. Hramov ◽  
Nikita S. Frolov ◽  
Vladimir A. Maksimenko ◽  
Semen A. Kurkin ◽  
Viktor B. Kazantsev ◽  
...  
Keyword(s):  
Functional Networks ◽  
Connectivity Restoration ◽  
Dynamic Integration ◽  
The Brain

Functional networks of the brain: from connectivity restoration to dynamic integration

2020 ◽  
Author(s):  
Aleksandr E. Hramov ◽  
Nikita S. Frolov ◽  
Vladimir A. Maksimenko ◽  
Semen A. Kurkin ◽  
Viktor B. Kazantsev ◽  
...  
Keyword(s):  
Functional Networks ◽  
Connectivity Restoration ◽  
Dynamic Integration ◽  
The Brain

Neural and Environmental Modulation of Motivation

2018 ◽  
Author(s):  
Thomas Douglas
Keyword(s):  
Environmental Influence ◽  
Environmental Intervention ◽  
Argument Proceeds ◽  
The Brain ◽  
Moral Difference ◽  
Do So

Interventions that modify a person’s motivations through chemically or physically influencing the brain seem morally objectionable, at least when they are performed nonconsensually. This chapter raises a puzzle for attempts to explain their objectionability. It first seeks to show that the objectionability of such interventions must be explained at least in part by reference to the sort of mental interference that they involve. It then argues that it is difficult to furnish an explanation of this sort. The difficulty is that these interventions seem no more objectionable, in terms of the kind of mental interference that they involve, than certain forms of environmental influence that many would regard as morally innocuous. The argument proceeds by comparing a particular neurointervention with a comparable environmental intervention. The author argues, first, that the two dominant explanations for the objectionability of the neurointervention apply equally to the environmental intervention, and second, that the descriptive difference between the environmental intervention and the neurointervention that most plausibly grounds the putative moral difference in fact fails to do so. The author concludes by presenting a trilemma that falls out of the argument.

“Don’t praise the day before the sunset”: Paremiology in the study of depressiveness

2021 ◽  
pp. 1354067X2110257
Author(s):  
Mariusz Wołońciej ◽  
Michał Wilczewski ◽  
Shulamith Kreitler
Keyword(s):  
Mental Disorders ◽  
Affective Disorders ◽  
Personal Experience ◽  
Mental States ◽  
Important Research ◽  
Adequate Model ◽  
Narrative Structures ◽  
Collective Experience ◽  
Practical Implications ◽  
Different Levels

Psychology and psychiatry are in a constant search for an adequate model of affective disorders. Psychology has classified depression as a mood disorder, but a growing literature links mental disorders with socioculturally relevant ways in which people experience and express distress. With this study, we link depression with proverbs as omnipresent narrative structures and mini-theories that help people interpret reality and categorize personal experience. Proverbs are omnipresent narrative structures that describe, explain, and prescribe human behavior. Hence, we offer a paremiological approach to better understand the minds of the depressed. Our tenet is that proverbs may also reflect people’s mental states and attitudes by conveying different levels of optimism versus pessimism. We evidence empirically that proverbs convey optimistic and pessimistic attitudes and, thus, have the capacity to capture peoples’ mental states. Moreover, we show that this capacity is limited for people with high depressiveness. Finally, we discuss how proverbial thinking links collective experience and wisdom imprinted in proverbs with an individual’s mental states, which has important research and practical implications.

scholarly journals Propositionalism and Questions that do not have Correct Answers

Erkenntnis ◽  
2021 ◽  
Author(s):  
Giulia Felappi
Keyword(s):  
Mental State ◽  
Mental States ◽  
Prima Facie ◽  
Mental Life ◽  
Do So

AbstractAs the label suggests, according to propositionalism, each intentional mental state, attitude or event is or involves a relation to a proposition. In this paper, I will discuss a case that seems prima facie not to be accountable for by propositionalism. After having presented the case, I will show why it is different from others that have been discussed in the literature as able to show that propositionalism cannot be correct. I will then consider what the propositionalist can say to fix the problem and I will show that no strategy that is genuinely propositionalist seems promising. I will not conclude that propositionalism is doomed. But I will show that if propositionalism can account for our case at all, it can only do so by losing its main appeal, i.e. its elegance and simplicity. But then propositionalism seems to have lost its advantage with respect to its obvious alternative, i.e. a pluralist account according to which mental states, attitudes and events are not all homogeneously relations to propositions, but rather our mental life should be accounted for in terms of a plurality of kinds of relata.

Behavioral measures and EEG monitoring using the Brain Symmetry Index during the Wada test in children

2012 ◽  
Vol 23 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Jurriaan M. Peters ◽  
Meritxell Tomas-Fernandez ◽  
Michel J.A.M. van Putten ◽  
Tobias Loddenkemper
Keyword(s):  
Eeg Monitoring ◽  
Wada Test ◽  
Behavioral Measures ◽  
Symmetry Index ◽  
The Brain

scholarly journals Using electrodermal activity to validate multilevel pain stimulation in healthy volunteers evoked by thermal grills

2020 ◽  
Vol 319 (3) ◽  
pp. R366-R375
Author(s):  
Hugo F. Posada-Quintero ◽  
Youngsun Kong ◽  
Kimberly Nguyen ◽  
Cara Tran ◽  
Luke Beardslee ◽  
...  
Keyword(s):  
Tissue Injury ◽  
Electrodermal Activity ◽  
Pain Scale ◽  
Potential Harm ◽  
Electric Pulses ◽  
Stimulation Level ◽  
Highly Correlated ◽  
The Brain ◽  
Different Levels ◽  
Assessment Research

We have tested the feasibility of thermal grills, a harmless method to induce pain. The thermal grills consist of interlaced tubes that are set at cool or warm temperatures, creating a painful “illusion” (no tissue injury is caused) in the brain when the cool and warm stimuli are presented collectively. Advancement in objective pain assessment research is limited because the gold standard, the self-reporting pain scale, is highly subjective and only works for alert and cooperative patients. However, the main difficulty for pain studies is the potential harm caused to participants. We have recruited 23 subjects in whom we induced electric pulses and thermal grill (TG) stimulation. The TG effectively induced three different levels of pain, as evidenced by the visual analog scale (VAS) provided by the subjects after each stimulus. Furthermore, objective physiological measurements based on electrodermal activity showed a significant increase in levels as stimulation level increased. We found that VAS was highly correlated with the TG stimulation level. The TG stimulation safely elicited pain levels up to 9 out of 10. The TG stimulation allows for extending studies of pain to ranges of pain in which other stimuli are harmful.

Accessing offshoring advantages: what and how to offshore

2015 ◽  
Vol 8 (2/3) ◽  
pp. 262-283 ◽  
Author(s):  
Alona Mykhaylenko ◽  
Ágnes Motika ◽  
Brian Vejrum Waehrens ◽  
Dmitrij Slepniov
Keyword(s):  
Performance Outcomes ◽  
Offshore Outsourcing ◽  
Strategic Decisions ◽  
Content Type ◽  
Different Types ◽  
Captive Offshoring ◽  
Performance Results ◽  
Governance Modes ◽  
Different Levels ◽  
Do So

Purpose – The purpose of this paper is to advance the understanding of factors that affect offshoring performance results. To do so, this paper focuses on the access to location-specific advantages, rather than solely on the properties of the offshoring company, its strategy or environment. Assuming that different levels of synergy may exist between particular offshoring strategic decisions (choosing offshore outsourcing or captive offshoring and the type of function) and different offshoring advantages, this work advocates that the actual fact of realization of certain offshoring advantages (getting or not getting access to them) is a more reliable predictor of offshoring success. Design/methodology/approach – A set of hypotheses derived from the extant literature is tested on the data from a quantitative survey of 1,143 Scandinavian firms. Findings – The paper demonstrates that different governance modes and types of offshored function indeed provide different levels of access to different types of location-specific offshoring advantages. This difference may help to explain the ambiguity of offshoring initiatives performance results. Research limitations/implications – Limitations of the work include using only the offshoring strategy elements and only their limited variety as factors potentially influencing access to offshoring advantages. Also, the findings are limited to Scandinavian companies. Originality/value – The paper introduces a new concept of access, which can help to more reliably predict performance outcomes of offshoring initiatives. Recommendations are also provided to practitioners dealing with offshoring initiatives.

scholarly journals Wisdom and fluid intelligence are dissociable in healthy older adults

2021 ◽  
pp. 1-11
Author(s):  
Cutter A. Lindbergh ◽  
Heather Romero-Kornblum ◽  
Sophia Weiner-Light ◽  
J. Clayton Young ◽  
Corrina Fonseca ◽  
...  
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
San Francisco ◽  
Fluid Intelligence ◽  
Memory Performance ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Self Report ◽  
Cross Sectional ◽  
Healthy Older Adults

ABSTRACT Objectives: The relationship between wisdom and fluid intelligence (Gf) is poorly understood, particularly in older adults. We empirically tested the magnitude of the correlation between wisdom and Gf to help determine the extent of overlap between these two constructs. Design: Cross-sectional study with preregistered hypotheses and well-powered analytic plan (https://osf.io/h3pjx). Setting: Memory and Aging Center at the University of California San Francisco, located in the USA. Participants: 141 healthy older adults (mean age = 76 years; 56% female). Measurements: Wisdom was quantified using a well-validated self-report-based scale (San Diego Wisdom Scale or SD-WISE). Gf was assessed via composite measures of processing speed (Gf-PS) and executive functioning (Gf-EF). The relationships of SD-WISE scores to Gf-PS and Gf-EF were tested in bivariate correlational analyses and multiple regression models adjusted for demographics (age, sex, and education). Exploratory analyses evaluated the relationships between SD-WISE and age, episodic memory performance, and dorsolateral and ventromedial prefrontal cortical volumes on magnetic resonance imaging. Results: Wisdom showed a small, positive association with Gf-EF (r = 0.181 [95% CI 0.016, 0.336], p = .031), which was reduced to nonsignificance upon controlling for demographics, and no association with Gf-PS (r = 0.019 [95% CI −0.179, 0.216], p = .854). Wisdom demonstrated a small, negative correlation with age (r = −0.197 [95% CI −0.351, −0.033], p = .019), but was not significantly related to episodic memory or prefrontal volumes. Conclusions: Our findings indicate that most of the variance in wisdom (>95%) is unaccounted for by Gf. The independence of wisdom from cognitive functions that reliably show age-associated declines suggests that it may hold unique potential to bolster decision-making, interpersonal functioning, and other everyday activities in older adults.

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