scholarly journals Edges in brain networks: contributions to models of structure and function

2021 ◽  
pp. 1-63
Author(s):  
Joshua Faskowitz ◽  
Richard F Betzel ◽  
Olaf Sporns
Keyword(s):  
Network Models ◽  
Brain Network ◽  
Higher Order ◽  
Dynamic Information ◽  
Brain Organization ◽  
Network Nodes ◽  
Different Types ◽  
Definition Of ◽  
And Function ◽  
Specific Definition

Abstract Network models describe the brain as sets of nodes and edges that represent its distributed organization. So far, most discoveries in network neuroscience have prioritized insights that highlight distinct groupings and specialized functional contributions of network nodes. Importantly, these functional contributions are determined and expressed by the web of their interrelationships, formed by network edges. Here, we underscore the important contributions made by brain network edges for understanding distributed brain organization. Different types of edges represent different types of relationships, including connectivity and similarity among nodes. Adopting a specific definition of edges can fundamentally alter how we analyze and interpret a brain network. Furthermore, edges can associate into collectives and higher-order arrangements, describe time series, and form edge communities that provide insights into brain network topology complementary to the traditional node-centric perspective. Focusing on the edges, and the higher-order or dynamic information they can provide, discloses previously underappreciated aspects of structural and functional network organization.

R&D Support Programs (the Need)

2017 ◽  
pp. 1-25
Keyword(s):  
Business Plan ◽  
Structure And Function ◽  
Support Program ◽  
Support Programs ◽  
Legal Environment ◽  
Support Tools ◽  
Different Types ◽  
Strategic Role ◽  
Definition Of ◽  
And Function

Any good business plan starts with the definition of the need for which it intends to base the entire business. Following that example, the discussion here should also start with the need for such programs, their strategic role as defined by research, and the rationale that makes them prevalent. When discussing R&D support programs, one needs to bear in mind that there are different types of such programs. The specific needs such programs were designed to answer, whether well or less so, the target audience or clients they address, and the specific legal environment they operate in, influence the different types and give rise to the need for different types of programs to begin with. In this chapter, we shall define the R&D support program and analyze examples of the influence the parameters mentioned above, have on the structure and function of the programs. The different types as well as support tools will be discussed at a later chapter (Chapter 05 – R&D support program types).

scholarly journals Terminology as a key uncertainty in net land use and land cover change carbon flux estimates

2014 ◽  
Vol 5 (1) ◽  
pp. 177-195 ◽  
Author(s):  
J. Pongratz ◽  
C. H. Reick ◽  
R. A. Houghton ◽  
J. I. House
Keyword(s):  
Land Use ◽  
Land Cover ◽  
Land Cover Change ◽  
Carbon Flux ◽  
Scientific Application ◽  
The Past ◽  
Different Types ◽  
Definition Of ◽  
Specific Definition ◽  
Terminological Confusion

Abstract. Reasons for the large uncertainty in land use and land cover change (LULCC) emissions go beyond recognized issues related to the available data on land cover change and the fact that model simulations rely on a simplified and incomplete description of the complexity of biological and LULCC processes. The large range across published LULCC emission estimates is also fundamentally driven by the fact that the net LULCC flux is defined and calculated in different ways across models. We introduce a conceptual framework that allows us to compare the different types of models and simulation setups used to derive land use fluxes. We find that published studies are based on at least nine different definitions of the net LULCC flux. Many multi-model syntheses lack a clear agreement on definition. Our analysis reveals three key processes that are accounted for in different ways: the land use feedback, the loss of additional sink capacity, and legacy (regrowth and decomposition) fluxes. We show that these terminological differences, alone, explain differences between published net LULCC flux estimates that are of the same order as the published estimates themselves. This has consequences for quantifications of the residual terrestrial sink: the spread in estimates caused by terminological differences is conveyed to those of the residual sink. Furthermore, the application of inconsistent definitions of net LULCC flux and residual sink has led to double-counting of fluxes in the past. While the decision to use a specific definition of the net LULCC flux will depend on the scientific application and potential political considerations, our analysis shows that the uncertainty of the net LULCC flux can be substantially reduced when the existing terminological confusion is resolved.

scholarly journals Terminology as a key uncertainty in net land use flux estimates

2013 ◽  
Vol 4 (2) ◽  
pp. 677-716 ◽  
Author(s):  
J. Pongratz ◽  
C. H. Reick ◽  
R. A. Houghton ◽  
J. House
Keyword(s):  
Land Use ◽  
Land Cover ◽  
Land Cover Change ◽  
Large Range ◽  
Scientific Application ◽  
Different Types ◽  
Definition Of ◽  
High Uncertainty ◽  
Specific Definition ◽  
Terminological Confusion

Abstract. Reasons for the high uncertainty in land use and land cover change (LULCC) emissions go beyond recognized issues to do with available data on land cover change and the fact that model simulations rely on a simplified and incomplete description of the complexity of biological and LULCC processes. The large range across published LULCC emission estimates is also fundamentally to do with the exact definition of the net land use flux with respect to the way it is calculated by models. We introduce a conceptual framework that allows us to compare the different types of models and simulation setups used to derive land use fluxes. We find that published studies are based on at least 9 different definitions of the net land use flux. Our analysis reveals three key processes that are accounted for in different ways: the land use feedback, the loss of additional sink capacity, and legacy (regrowth and decomposition) fluxes. We show that these terminological differences, alone, explain differences between published net land use flux estimates that are of the order of published estimates. While the decision to use a specific definition will depend on the scientific application and potential political considerations, our analysis shows that the uncertainty of the net land use flux can be substantially reduced when the existing terminological confusion is resolved.

Is there teleological order in nature? is there teleological explanation in science?

EPISTEMOLOGIA ◽  
2012 ◽  
pp. 211-220
Author(s):  
Paul Weingartner
Keyword(s):  
Higher Order ◽  
Teleological Explanation ◽  
Different Types ◽  
Definition Of

The paper will be divided into two parts. In the first part concerning teleological order in nature, different types of order will be distinguished: beginning with order as structure and then proceeding to higher and stronger types of order, which include special arithmetical and geometrical relations and eventually also negentropy. It will be shown that certain processes of becoming can possess higher order in such a way that they can have teleological order. In the second part a definition of teleological explanation will be given and the following two questions will be answered: (1) Are there teleological explanations which are logically valid? (2) Are there teleological explanations which are used by scientists?

scholarly journals New Public Monuments: Urban Art and Everyday Aesthetic Experience

2019 ◽  
Vol 2 (1) ◽  
pp. 30-38 ◽  
Author(s):  
Sanna Lehtinen
Keyword(s):  
Public Art ◽  
Large Scale ◽  
Aesthetic Experience ◽  
Urban Art ◽  
Public Monuments ◽  
New Public ◽  
Different Types ◽  
The Aesthetic ◽  
Definition Of ◽  
And Function

AbstractThe role and function of public art is currently undergoing some large-scale changes. Many new artworks which are situated within the already existing urban sphere, seem to be changing the definition of public art, each in their own way. Simultaneously, there exists a trend that endorses more traditional forms of public art. Juxtaposing and comparing the aesthetic implications of different types of artworks, it is possible to see how they contribute to the contemporary understanding of the urban sphere. In this paper, I take a look at the explicit and implicit aesthetic values that these simultaneously existing contemporary forms of public art are based on. The cases selected for closer look are examples of prominent and recent works of public art from downtown Helsinki: He who Brings the Light (unveiled in 2017) by Pekka Kauhanen and Running Man (performed in 2016-17) by Nestori Syrjala. What space and what kind of position is subscribed to the perceiver by these very different types of yet equally established artworks? What kind of experiences and possibilities of participation do these works entail? The focus is on the undergoing redefinition of public art that revolves around these questions.

scholarly journals Meta-connectomics: human brain network and connectivity meta-analyses

2016 ◽  
Vol 46 (5) ◽  
pp. 897-907 ◽  
Author(s):  
N. A. Crossley ◽  
P. T. Fox ◽  
E. T. Bullmore
Keyword(s):  
Network Analysis ◽  
Psychiatric Disorders ◽  
Brain Connectivity ◽  
Network Models ◽  
Brain Network ◽  
Primary Data ◽  
Exciting Field ◽  
Brain Organization ◽  
Rich Club ◽  
General Importance

Abnormal brain connectivity or network dysfunction has been suggested as a paradigm to understand several psychiatric disorders. We here review the use of novel meta-analytic approaches in neuroscience that go beyond a summary description of existing results by applying network analysis methods to previously published studies and/or publicly accessible databases. We define this strategy of combining connectivity with other brain characteristics as ‘meta-connectomics’. For example, we show how network analysis of task-based neuroimaging studies has been used to infer functional co-activation from primary data on regional activations. This approach has been able to relate cognition to functional network topology, demonstrating that the brain is composed of cognitively specialized functional subnetworks or modules, linked by a rich club of cognitively generalized regions that mediate many inter-modular connections. Another major application of meta-connectomics has been efforts to link meta-analytic maps of disorder-related abnormalities or MRI ‘lesions’ to the complex topology of the normative connectome. This work has highlighted the general importance of network hubs as hotspots for concentration of cortical grey-matter deficits in schizophrenia, Alzheimer's disease and other disorders. Finally, we show how by incorporating cellular and transcriptional data on individual nodes with network models of the connectome, studies have begun to elucidate the microscopic mechanisms underpinning the macroscopic organization of whole-brain networks. We argue that meta-connectomics is an exciting field, providing robust and integrative insights into brain organization that will likely play an important future role in consolidating network models of psychiatric disorders.

Kontrast und Wissen

2009 ◽  
Vol 54 (1) ◽  
pp. 69-102
Author(s):  
Robin Rehm
Keyword(s):  
19Th Century ◽  
Edmund Husserl ◽  
Specific Knowledge ◽  
Max Scheler ◽  
Black And White ◽  
Black Circle ◽  
Black Cross ◽  
Definition Of ◽  
And Function ◽  
The 19Th Century

Kasimir Malewitschs suprematistische Hauptwerke ›Schwarzes Quadrat‹, ›Schwarzer Kreis‹ und ›Schwarzes Kreuz‹ von 1915 setzen sich aus schwarzen Formen auf weißem Grund zusammen. Der Typus des Schwarzweißbildes weist überraschende Parallelen zu den bildlichen Wahrnehmungsinstrumenten auf, die vom ausgehenden 18. bis Anfang des 20. Jahrhunderts in den Experimenten der Farbenlehre, physiologischen Optik und Psychologie verwendet worden sind. Die vorliegende Studie untersucht diese Parallelen in drei Schritten: Zunächst erfolgt eine allgemeine Charakterisierung des Schwarzweißbildes mit Hilfe des Kontrastbegriffs von Edmund Husserl. Des weiteren wird die Entstehung und Funktion des schwarzweißen Kontrastbildes in den Wissenschaften des 19. Jahrhunderts typologisch herausgearbeitet. Unter Berücksichtigung des Wissensbegriffs von Max Scheler wird abschließend die Spezifik des Wissens eruiert, das die Schwarzweißbilder sowohl in der Malerei Malewitschs als auch in den genannten Wissenschaften generieren. Malevich’s main Suprematist works, such as ›Black Square‹, ›Black Circle‹, and ›Black Cross‹ from 1915, consist of black shapes on white ground. Surprisingly this series of shapes strongly resembles scientific black-and-white images used for research on colour theory, physiological optics, and psychology throughout the 19th century. This paper examines the parallels between Malevich’s paintings and the scientific drawings in three steps: It first characterizes black-and-white images in general, using Edmund Husserl’s definition of the term ›contrast‹. Secondly, the paper investigates the development and function of black-and-white images as tools of perception in the sciences. It finally discusses the specific knowledge generated through Malevich’s art and through scientific black-and-white images, following Max Scheler’s phenomenological identification of knowledge.

A Strategy for Design of Marine Pollution Monitoring Studies

1986 ◽  
Vol 18 (4-5) ◽  
pp. 15-26 ◽  
Author(s):  
D. A. Segar ◽  
E. Stamman
Keyword(s):  
Information Needs ◽  
Marine Pollution ◽  
Monitoring Program ◽  
Pollution Monitoring ◽  
Systematic Evaluation ◽  
Management Information ◽  
Different Types ◽  
Management Context ◽  
Definition Of ◽  
Scientific Testing

Most historical marine pollution monitoring has proven useless in a management context. A strategy for development of effective marine pollution monitoring programs is outlined. This strategy is based on the following steps: 1) systematic evaluation of the management information needs, 2) identification of the hypothetical impacts associated with those management concerns, and 3) investigation of the feasibility of monitoring those effects such that the existence, or absence, of a specified level of effects can be established in a statistically-valid manner. There are two fundamentally different types of monitoring program: site-specific and regional. These two types of program differ markedly in scope and approach when designed through application of this strategy. The strategy requires development of null hypotheses which address management concerns and which are amenable to scientific testing. In order for the program to be successful, the null hypotheses selected for inclusion in a marine pollution monitoring program must address levels of effect which are predefined to be environmentally significant. The definition of environmentally significant effect levels is a difficult process which must be primarily the responsibility of the managerial community.

John among the Apocalypses

2020 ◽  
Author(s):  
Benjamin E. Reynolds
Keyword(s):  
Gospel Of John ◽  
Central Place ◽  
Reception History ◽  
Genre Theory ◽  
Synoptic Gospels ◽  
Book Of Revelation ◽  
Distinctive Features ◽  
History Of ◽  
Definition Of ◽  
And Function

The central place of revelation in the Gospel of John and the Gospel’s revelatory telling of the life of Jesus are distinctive features of John when compared with the Synoptic Gospels; yet, when John is compared among the apocalypses, these same features indicate John’s striking affinity with the genre of apocalypse. By paying attention to modern genre theory and making an extensive comparison with the standard definition of “apocalypse,” the Gospel of John reflects similarities with Jewish apocalypses in form, content, and function. Even though the Gospel of John reflects similarities with the genre of apocalypse, John is not an apocalypse, but in genre theory terms, John may be described as a gospel in kind and an apocalypse in mode. John’s narrative of Jesus’s life has been qualified and shaped by the genre of apocalypse, such that it may be called an “apocalyptic” gospel. Understanding the Fourth Gospel as “apocalyptic” Gospel provides an explanation for John’s appeal to Israel’s Scriptures and Mosaic authority. Possible historical reasons for the revelatory narration of Jesus’s life in the Gospel of John may be explained by the Gospel’s relationship with the book of Revelation and the history of reception concerning their writing. An examination of Byzantine iconographic traditions highlights how reception history may offer a possible explanation for reading John as “apocalyptic” Gospel.

Physicianship and the Rebirth of Medical Education

2018 ◽  
Author(s):  
J. Donald Boudreau ◽  
Eric Cassell ◽  
Abraham Fuks
Keyword(s):  
Medical Education ◽  
Educational Process ◽  
Medical Attention ◽  
Patient Centeredness ◽  
Goals Of Medicine ◽  
The Subject ◽  
Definition Of ◽  
And Function ◽  
William Osler ◽  
The Relationship

This book reimagines medical education and reconstructs its design. It originates from a reappraisal of the goals of medicine and the nature of the relationship between doctor and patient. The educational blueprint outlined is called the “Physicianship Curriculum” and rests on two linchpins. First is a new definition of sickness: Patients know themselves to be ill when they cannot pursue their purposes and goals in life because of impairments in functioning. This perspective represents a bulwark against medical attention shifting from patients to diseases. The curriculum teaches about patients as functional persons, from their anatomy to their social selves, starting in the first days of the educational program and continuing throughout. Their teaching also rests on the rock-solid grounding of medicine in the sciences and scientific understandings of disease and function. The illness definition and knowledge base together create a foundation for authentic patient-centeredness. Second, the training of physicians depends on and culminates in development of a unique professional identity. This is grounded in the historical evolution of the profession, reaching back to Hippocrates. It leads to reformulation of the educational process as clinical apprenticeships and moral mentorships. “Rebirth” in the title suggests that critical ingredients of medical education have previously been articulated. The book argues that the apprenticeship model, as experienced, enriched, taught, and exemplified by William Osler, constitutes a time-honored foundation. Osler’s “natural method of teaching the subject of medicine” is a precursor to the Physicianship Curriculum.

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