Copper(II) Oxide Nanoflakes Based Impedimetric Immunosensor for Label Free Determination of Cancer Antigen-125

2016 ◽  
Vol 14 (1) ◽  
pp. 97-101 ◽  
Author(s):  
Ragini Raghav ◽  
Sudha Srivastava
Keyword(s):  
Label Free ◽  
Cancer Antigen 125 ◽  
Cancer Antigen ◽  
Impedimetric Immunosensor

A label-free impedimetric immunosensor for direct determination of the textile dye Disperse Orange 1

Talanta ◽  
2015 ◽  
Vol 142 ◽  
pp. 183-189 ◽  
Author(s):  
Jing Yang ◽  
Carolina Gomes da Rocha ◽  
Shengfu Wang ◽  
Antonio Aparecido Pupim Ferreira ◽  
Hideko Yamanaka
Keyword(s):  
Direct Determination ◽  
Textile Dye ◽  
Label Free ◽  
Impedimetric Immunosensor

scholarly journals Determination of cancer antigen 125 in ovarian carcinoma

2003 ◽  
Vol 18 (2) ◽  
pp. 27-33 ◽  
Author(s):  
V. Thakur ◽  
A. K. Anand ◽  
U. Mukherjee ◽  
D. Ghosh
Keyword(s):  
Ovarian Carcinoma ◽  
Cancer Antigen 125 ◽  
Cancer Antigen

Study on the Novel Label Free Impedimetric Immunosensor for Aflatoxin B1 Based on Poly(o-phenylenediamine) Film Modified Gold Electrode

2011 ◽  
Vol 322 ◽  
pp. 385-389 ◽  
Author(s):  
Ning Ning Wu ◽  
Li Xin Cao ◽  
Pei Sheng Yan ◽  
Ming Hao Wang
Keyword(s):  
Aflatoxin B1 ◽  
Gold Electrode ◽  
Biomolecular Recognition ◽  
The Novel ◽  
Label Free ◽  
Buffer Solution ◽  
Solution Ph ◽  
Linear Detection ◽  
Impedimetric Immunosensor

A label free impedimetric immunosensor for the determination of aflatoxin B1 (AFB1) was fabricated by immobilizing anti-AFB1 onto Poly o-phenylenediamine (PoPD) electropolymerized film modified gold electrode by glutaraldehyde (GA) cross-linking. An electrochemical interfacial modeling of biomolecular recognition was recommended and reasonably interpreted. EIS technology was employed for the quantitative determination. The linear detection concentration ranges of AFB1 were 0.03~0.1 μg/mL and 0.1~0.7 μg/mL. The detection limit was 2.8×10-8μg/mL. The immunosensor could be reused more than 10 times when renewed by HCl-Glycine buffer solution (pH 2.6).

scholarly journals Luminoimmunometric Assay of Tissue Polypeptide Antigen (Tpa) and Cancer Antigen 125 (Ca-125) in Breast Cancer Patients

1993 ◽  
Vol 11 (2-3) ◽  
pp. 83-90
Author(s):  
O. El-Ahmady ◽  
Halim A.-B. ◽  
S. Eissa
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Ca 125 ◽  
Healthy Controls ◽  
Breast Cancer Patients ◽  
Tissue Polypeptide Antigen ◽  
Cancer Antigen 125 ◽  
Cancer Antigen

Serum TPA and CA-125 were determined in 86 individuals (66 with breast cancer representing the different stages and grades of the disease and 20 normal healthy controls). TPA and CA-125 were estimated using the L1A reagents supplied by BYK Sangtec. TPA showed sensitivity rates of 31.8%, 42.4% and 51.5% while CA-125 showed sensitivities of 16.3%, 18.6% and 25.6% at specificity levels of 100%, 95% and 90% respectively. Combined determination of the two markers resulted in some improvement in sensitivity. For follow-up of breast cancer patients after surgery both markers were of value and showed near-identical patterns.

scholarly journals The diagnostics significance of serum cancer antigen-125 in abdominal tuberculosis

2018 ◽  
Vol 5 (2) ◽  
pp. 474 ◽  
Author(s):  
Anil Kumar ◽  
Shiv S. Paswan ◽  
Bindey Kumar ◽  
Pragati Raj ◽  
. Sunita
Keyword(s):  
Disease Activity ◽  
Abdominal Tuberculosis ◽  
Serum Levels ◽  
Serum Markers ◽  
Ca 125 ◽  
Control Group ◽  
Cancer Antigen 125 ◽  
Cancer Antigen ◽  
Serial Measurement

Background: Various serum markers have been shown to be helpful in diagnosing tubercular infection, but none has been proven to be specific. The present study was undertaken to ascertain the role of serum cancer antigen (CA) -125 in diagnosing and monitoring therapeutic response in abdominal tuberculosis.Methods: Fifty diagnosed cases of abdominal tuberculosis and equal number of controls were included in the study. All the patients underwent clinical, radiological and hematological examination. Twenty-two patients had acute presentation and underwent laparotomy and twenty-eight patients had a chronic presentation and were managed conservatively. Biopsy was taken in all patients undergoing laparotomy. Serial measurement of serum levels of CA-125 were done at 0, 3 and 6 months in all the patients.Results: The CA-125 levels were significantly higher in tuberculosis patients than in control group (PPV 95.74% at 0 month). It was also observed that the levels correlated significantly with the disease activity (sensitivity 90 percent, specificity 96 percent) and return to normal level with the treatment given. It was shown that sensitivity reduced to 12 percent and 6 percent at 3 months and 6 months respectively after completion of treatment. The specificity however remained unchanged.Conclusions: The measurement of CA-125 may be a valuable parameter in diagnosing and determination of disease activity in abdominal tuberculosis.

scholarly journals Electrochemical-Based Serological Detection of Bovine Immunoglobulin G in Calves

2020 ◽  
Author(s):  
Caoimhe Robinson ◽  
Niamh Creedon ◽  
Riona sayers ◽  
emer kennedy ◽  
Alan O'Riordan
Keyword(s):  
Immunoglobulin G ◽  
Rapid Determination ◽  
Passive Transfer ◽  
Label Free ◽  
Serological Detection ◽  
New Born ◽  
Risk Of Mortality ◽  
Bovine Immunoglobulin ◽  
Impedimetric Immunosensor

Bovine antibodies, such as immunoglobulin G (IgG), cannot pass the placental barrier and as such are not transferred from the mother to the foetus,<i> in utero</i>. Instead a calf must absorb antibodies following ingestion of colostrum postpartum. Failure of Passive Transfer (FPT) is a condition that predisposes calves to development of disease and increases the risk of mortality. Thus, continuous early monitoring of IgG absorption in a calf, within the first 24 hours of life, is imperative to allow faster treatment and prevent FPT. In this paper, we present the development of a label-free impedimetric immunosensor device for bovine IgG in serum and demonstrate its suitability to determine early FPT in new-born calves. The developed sensors were challenged to discriminate between new born calf sera, both pre- and post-colostrum feeding, and demonstrated efficent detection of IgG in under 15 minutes. Such a device could enable rapid determination of FPT, thereby improving calves’ vitality and survival rate

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