Relationships between Age, Blood Pressure, and Retinal Vessel Diameters in an Older Population

2003 ◽  
Vol 44 (7) ◽  
pp. 2900 ◽  
Author(s):  
Harry Leung ◽  
Jie Jin Wang ◽  
Elena Rochtchina ◽  
Ava G. Tan ◽  
Tien Y. Wong ◽  
...  
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anouk W. Vaes ◽  
Martijn A. Spruit ◽  
Karel Van Keer ◽  
João Barbosa-Breda ◽  
Emiel F. M. Wouters ◽  
...  

AbstractCardiovascular diseases are frequently present in chronic obstructive pulmonary disease (COPD). Population-based studies found associations between retinal vessel diameters and cardiovascular health, but it is unknown whether this also applies to COPD patients. Therefore, we measured retinal vessel diameters in COPD patients and aimed to determine the association with cardiovascular risk factors, lung function, and functional outcomes. In addition, we investigated whether an exercise-based pulmonary rehabilitation (PR) program would change retinal vessel diameters, as a proxy for improved microvascular health. Demographics and clinical characteristics, including pulmonary function, exercise capacity, blood pressure, blood measurements and level of systemic inflammation were obtained from 246 patients during routine assessment before and after PR. Retinal vessel diameters were measured from digital retinal images. Older age and higher systolic blood pressure were associated with narrower retinal arterioles (β: −0.224; p = 0.042 and β: −0.136; p < 0.001, respectively). Older age, higher systolic blood pressure and lower level of systemic inflammation were associated with narrower retinal venules (β: −0.654; −0.229; and −13.767, respectively; p < 0.05). No associations were found between retinal vessel diameters and lung function parameters or functional outcomes. After PR, no significant changes in retinal venular or arteriolar diameter were found. To conclude, retinal vessel diameters of COPD patients were significantly associated with systolic blood pressure and systemic inflammation, whilst there was no evidence for an association with lung function parameters, functional outcomes or other cardiovascular risk factors. Furthermore, an exercise-based PR program did not affect retinal vessel diameter.


2018 ◽  
Vol 60 (3) ◽  
pp. 234-240 ◽  
Author(s):  
Ja K. Gu ◽  
Luenda E. Charles ◽  
Ronald Klein ◽  
Lisa M. Grady ◽  
Claudia C. Ma ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Dragana Drobnjak ◽  
Inger Christine Munch ◽  
Charlotte Glümer ◽  
Kristine Faerch ◽  
Line Kessel ◽  
...  

Purpose. To describe associations between retinal vessel diameters and cardiovascular risk markers and mortality.Methods. The present study included 908 persons aged 30 to 60 years. Vessel diameters were expressed as central retinal venular equivalent (CRVE) and central retinal arteriolar equivalent (CRAE). Multiple linear regression analyses and Cox regression models were used.Results. Multiple linear regression analyses showed that narrower CRAE was associated with higher systolic blood pressure, age, and higher HDL cholesterol, whereas wider CRAE and CRVE were associated with smoking. Narrower CRVE was associated with higher HDL cholesterol. In an age-adjusted model, associations between wider CRVE and risk of ischemic heart disease were found (P<0.001). Wider CRVE was associated with all-cause mortality (HR = 2.02,P=0.033) in a model adjusted for age, gender, and blood pressure. However, the association was not statistically significant after additional adjustment for smoking.Conclusions. The associations between retinal vessel diameters and known cardiovascular risk factors were confirmed. All-cause mortality was not associated with retinal vessel diameters when adjusting for relevant confounders.


2006 ◽  
Vol 47 (8) ◽  
pp. 3539 ◽  
Author(s):  
Nina C. B. B. Taarnhøj ◽  
Michael Larsen ◽  
Birgit Sander ◽  
Kirsten O. Kyvik ◽  
Line Kessel ◽  
...  

2017 ◽  
Vol 27 (8) ◽  
pp. 529
Author(s):  
Ja K. Gu ◽  
Luenda E. Charles ◽  
Claudia C. Ma ◽  
Penelope Baughman ◽  
John M. Violanti ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Markus Gerber ◽  
Katharina Endes ◽  
Christian Herrmann ◽  
Flora Colledge ◽  
Serge Brand ◽  
...  

Background. Strong evidence exists showing that psychosocial stress plays an important part in the development of cardiovascular diseases. Because physical inactivity is associated with less favourable retinal vessel diameter and blood pressure profiles, this study explores whether physical fitness is able to buffer the negative effects of psychosocial stress on retinal vessel diameters and blood pressure in young children.Methods. 325 primary schoolchildren (51% girls,Mage=7.28years) took part in this cross-sectional research project. Retinal arteriolar diameters, retinal venular diameters, arteriolar to venular ratio, and systolic and diastolic blood pressure were assessed in all children. Interactions terms between physical fitness (performance in the 20 m shuttle run test) and four indicators of psychosocial stress (parental reports of critical life events, family, peer and school stress) were tested in a series of hierarchical regression analyses.Results. Critical life events and family, peer, and school-related stress were only weakly associated with retinal vessel diameters and blood pressure. No support was found for a stress-buffering effect of physical fitness.Conclusion. More research is needed with different age groups to find out if and from what age physical fitness can protect against arteriolar vessel narrowing and the occurrence of other cardiovascular disease risk factors.


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