scholarly journals The Role of RPE Cell-Associated VEGF189in Choroidal Endothelial Cell Transmigration across the RPE

2011 ◽  
Vol 52 (1) ◽  
pp. 570 ◽  
Author(s):  
Haibo Wang ◽  
Pete Geisen ◽  
Erika S. Wittchen ◽  
Bradley King ◽  
Keith Burridge ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Choroidal Endothelial Cell

scholarly journals The role of anti-endothelial cell antibodies in Kawasaki disease -in vitro and in vivo studies

2002 ◽  
Vol 130 (2) ◽  
pp. 233-240 ◽  
Author(s):  
E. GRUNEBAUM ◽  
M. BLANK ◽  
S. COHEN ◽  
A. AFEK ◽  
J. KOPOLOVIC ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Kawasaki Disease ◽  
In Vivo Studies

scholarly journals The Role of Putative Fibrinogen Aα-, Bβ-, and γA-chain Integrin Binding Sites in Endothelial Cell-mediated Clot Retraction

1997 ◽  
Vol 272 (35) ◽  
pp. 22080-22085 ◽  
Author(s):  
Richard A. Smith ◽  
M. W. Mosesson ◽  
Michael M. Rooney ◽  
Susan T. Lord ◽  
A.U. Daniels ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Binding Sites ◽  
Clot Retraction

scholarly journals Possible Protective Role of Melatonin in Pediatric Infectious Diseases and Neurodevelopmental Pathologies

2020 ◽  
Vol 10 (01) ◽  
pp. e104-e109
Author(s):  
Antonio Molina-Carballo ◽  
Antonio Emilio Jerez-Calero ◽  
Antonio Muñoz-Hoyos
Keyword(s):  
Endothelial Cell ◽  
Free Radical ◽  
Chronic Administration ◽  
Protective Role ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Energetic Metabolism ◽  
Beneficial Effects ◽  
Molecular Crosstalk

AbstractMelatonin, produced in every cell that possesses mitochondria, acts as an endogenous free radical scavenger, and improves energetic metabolism and immune function, by complex molecular crosstalk with other intracellular compounds. There is greatly increasing evidence regarding beneficial effects of acute and chronic administration of high melatonin doses, in infectious, developmental, and degenerative pathologies, as an endothelial cell and every cell protectant.

scholarly journals Role of endothelial cell receptors in the context of SARS-CoV-2 infection (COVID-19)

2021 ◽  
Vol 34 (2) ◽  
pp. 262-268
Author(s):  
Jun Zhang ◽  
Kristen M. Tecson ◽  
Peter A. McCullough
Keyword(s):  
Endothelial Cell ◽  
Cell Receptors

scholarly journals An autoantibody directed against human thrombin anion-binding exosite in a patient with arterial thrombosis: effects on platelets, endothelial cells, and protein C activation

Blood ◽  
1994 ◽  
Vol 84 (6) ◽  
pp. 1843-1850 ◽  
Author(s):  
E Arnaud ◽  
M Lafay ◽  
P Gaussem ◽  
V Picard ◽  
M Jandrot-Perrus ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Endothelial Cell ◽  
Arterial Thrombosis ◽  
Protein C ◽  
Receptor Activation ◽  
Anion Binding ◽  
Thrombin Receptor ◽  
Cell Functions ◽  
Human Thrombin

Abstract An autoantibody, developed by a patient with severe and recurrent arterial thrombosis, was characterized to be directed against the anion- binding exosite of thrombin, and inhibited all thrombin interactions requiring this secondary binding site without interfering with the catalytic site. The effect of the antibody was studied on thrombin interactions with platelets and endothelial cells from human umbilical veins (HUVEC). The autoantibody specifically and concentration- dependently inhibited alpha-thrombin-induced platelet activation and prostacyclin (PGI2) synthesis from HUVEC. It had no effect when gamma- thrombin or the thrombin receptor activation peptide SFLLR were the inducers. The effect of the antibody on protein C activation has been studied. The antibody blocked the thrombin-thrombomodulin activation of protein C. The inhibition of the activation was maximal with a low concentration of thrombomodulin. The fact that the autoantibody inhibited concentration-dependent alpha-thrombin-induced platelet and endothelial cell functions emphasizes the crucial role of the anion- binding exosite of thrombin to activate its receptor. In regard to the pathology, the antibody inhibited two vascular processes implicated in thrombin-antithrombotic functions, PGI2 secretion, and protein C activation, which could be implicated in this arterial thrombotic disease.

scholarly journals Role of the retinal vascular endothelial cell in ocular disease

2013 ◽  
Vol 32 ◽  
pp. 102-180 ◽  
Author(s):  
Arpita S. Bharadwaj ◽  
Binoy Appukuttan ◽  
Phillip A. Wilmarth ◽  
Yuzhen Pan ◽  
Andrew J. Stempel ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Vascular Endothelial Cell ◽  
Ocular Disease ◽  
Vascular Endothelial ◽  
Retinal Vascular Endothelial Cell

scholarly journals Role of endothelial cell hyperpolarization in EDHF-mediated responses in the guinea-pig carotid artery

2000 ◽  
Vol 129 (6) ◽  
pp. 1103-1112 ◽  
Author(s):  
J -F Quignard ◽  
M Félétou ◽  
G Edwards ◽  
J Duhault ◽  
A H Weston ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Carotid Artery ◽  
Guinea Pig
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