The Relationship of Undifferentiated Mesenchymal Cells to TMJ Articular Tissue Thickness

1992 ◽  
Vol 71 (11) ◽  
pp. 1816-1821 ◽  
Author(s):  
C.A. Bibb ◽  
A.G. Pullinger ◽  
F. Baldioceda

Undifferentiated mesenchymal (UM) cells, the progenitor cells of the cartilage layer, have been assigned a significant role in TMJ articular tissue maintenance. This was based on reports of UM cell reduction with increased soft-tissue thickness for the condyle and temporal component. However, the strength of this inverse relationship was not presented and remained unclear. The purpose of the present study was to assess the strength of the correlation between UM cell presence and soft-tissue thickness in young adult TMJs at autopsy. Sagittal histological sections from the central thirds of 50 joints were evaluated with respect to articular soft-tissue thickness, histological character, and UM cell presence in the condyle and temporal component. The superior sector ofthe condyle and the articular eminence showed the greatest variability in soft-tissue thickness and were the only areas to show localized UM cell absence. The eminence was the only location to show an inverse relationship between soft-tissue thickness and UM cell presence, and this was consistent in both an ANOVA (p = 0.0016) and a Spearman correlation analysis. However, the strength of this correlation was only moderate (rho = -0.52), and no such relationship was observed in any other location. This study suggests that the relationship between UM cell presence and soft-tissue thickness is more complex than previously hypothesized and that the contribution of UM cells to articular tissue maintenance has been overstated, while other biological processes were overlooked.

2019 ◽  
Vol 3 (4) ◽  
pp. 1405-1409
Author(s):  
Karly Anderson ◽  
Elizabeth Ries ◽  
Jacob Backes ◽  
Katherine Bishop ◽  
Miranda Boll ◽  
...  

Abstract The objective of this study was to contrast the soft tissue thickness, cranial thickness, total tissue thickness, cross-sectional brain area, and bolt–brain contact from the common frontal application of captive bolt euthanasia with the alternative location behind the ear in cadaver swine heads. Twenty-three cadaver heads from pigs that were approximately 136 kg and 6 mo of age were collected from a regional slaughter establishment following CO2 stunning and assigned to either the FRONTAL (n = 11) or the CAUDAL TO PINNA (n = 12) application of the captive bolt. The soft tissue thickness was different (P < 0.0001) between the 2 applications (FRONTAL: 8.3 ± 3.4 mm; CAUDAL TO PINNA: 56.5 ± 3.4 mm). The cranial thickness was different (P < 0.0001) between the applications (FRONTAL: 23.4 ± 2.9 mm; CAUDAL TO PINNA: 26.5 ± 2.9 mm). There was also a difference (P < 0.0001) in the total tissue thickness between the 2 applications (FRONTAL: 31.7 ± 3.8 mm; CAUDAL TO PINNA: 73.4 ± 3.8 mm). Cross-sectional area was calculated from images collected immediately after the heads were cut along the plane of bolt travel by bandsaw and was different (P = 0.0028) between the 2 applications (FRONTAL: 25.2 ± 1.3 cm2; CAUDAL TO PINNA: 18.9 ± 1.3 cm2). Bolt–brain contact was also assessed from the images, and a difference (P = 0.0360) between the 2 applications (FRONTAL: 100 ± 10.5%; CAUDAL TO PINNA: 66.7 ± 10.5%) was identified. The results of this study suggest that the FRONTAL application may provide a bolt path with less tissue to travel through when compared with the CAUDAL TO PINNA application for pigs of the approximate age and weight of those in this study. Ultimately, the FRONTAL location may present less risk for the captive bolt euthanasia of swine at market weight at this time. Additional refinement of the CAUDAL TO PINNA procedure and modification to the captive bolt device to penetrate to a suitable depth to ensure brain damage is recommended.


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 262-263
Author(s):  
Karly Anderson ◽  
Elizabeth Ries ◽  
Jacob Backes ◽  
Katherine Bishop ◽  
Miranda Boll ◽  
...  

Abstract The objective of this study was to contrast the soft tissue thickness, cranial thickness, total tissue thickness, cross-sectional brain area and bolt–brain contact from the common frontal application of captive bolt euthanasia with the alternative location behind the ear in cadaver swine heads. Twenty-three cadaver heads from pigs that were approximately 136 kg and 6 mo of age were collected from a slaughter establishment following CO2 stunning and assigned to either the FRONTAL (n = 11) or CAUDAL TO PINNA (n = 12) application of the captive bolt. The soft tissue thickness was different (P < 0.0001) between the 2 applications (FRONTAL: 8.3±3.4 mm; CAUDAL TO PINNA: 56.5±3.4 mm). The cranial thickness was different (P < 0.0001) between the applications (FRONTAL: 23.4±2.9 mm; CAUDAL TO PINNA: 26.5±2.9 mm). There was a difference (P < 0.0001) in the total tissue thickness between the 2 applications (FRONTAL: 31.7±3.8 mm; CAUDAL TO PINNA: 73.4±3.8 mm). Cross-sectional area was calculated from images collected immediately after the heads were cut along the plane of bolt travel by bandsaw and was different (P = 0.0028) between the 2 applications (FRONTAL: 25.2±1.3 cm2; CAUDAL TO PINNA: 18.9±1.3 cm2). Bolt–brain contact was also assessed from the images, and a difference (P = 0.0360) between the 2 applications (FRONTAL: 100±10.5%; CAUDAL TO PINNA: 66.7±10.5%) was identified. The results of this study suggest that the FRONTAL application may provide a bolt path with less tissue to travel through when compared with the CAUDAL TO PINNA application for pigs of the approximate age and weight of those in this study. Ultimately, the FRONTAL location may present less risk for the captive bolt euthanasia of swine at market weight at this time. Additional refinement of the CAUDAL TO PINNA procedure and modification to the captive bolt device to penetrate to a suitable depth to ensure brain damage is recommended.


2018 ◽  
Vol 10 (1) ◽  
pp. 1-8
Author(s):  
Daniele Gibelli ◽  
Matteo Zago ◽  
Annalisa Cappella ◽  
Claudia Dolci ◽  
Chiarella Sforza

Background: The anatomical assessment of the arrangement of facial soft tissues has important applications in different fields from orthodontics to plastic surgery. One of the issues concerns the relationship between facial soft tissue thickness and skeletal class. Literature mainly deals with adult populations, whereas very few studies have been focused on children. Objective: This study aims at investigating the relationship between midline facial soft tissue thickness and skeletal classes in Italian pre-treatment orthodontic child patients. Methods: Lateral cephalometric X-ray films were obtained from 220 healthy Caucasoid children (91 males and 129 females), aged between 6 and 18 years (Class I: 41 males and 70 females; Class II: 18 males and 25 females; Class III: 32 males and 34 females). All the films were digitized and 14 soft tissue thicknesses were measured on the midface; in addition, the skeletal class was assessed according to the corrected ANB angle (ANBc). Differences in facial soft tissue thickness according to sex and skeletal class were assessed through two-way ANOVA test (p<0.01). Results: Statistically significant differences according to sex were found for labrale superius, stomion and labrale inferius, with thicker soft tissues in males than in females (p<0.01). Only measurements at labrale superius and gnathion showed statistically significant differences according to skeletal class, with thicker soft tissues in Class III children and thinner ones in Class II children (p<0.01). Conclusion: The limited number of investigations, as well as the differences in protocols, renders the comparison of results from different studies difficult, suggesting further investigations to enlighten this complex and debated anatomical issue.


Author(s):  
Selda AKSOY ◽  
Mehmet Ali GÜNER ◽  
İnanç GÜVENÇ ◽  
Sedat BİLGE ◽  
Onur TEZEL

Objectives: The aim of the study was to determine the soft tissue thickness overlying the dorsal tubercle and the relationship with adjacent anatomical structures in the distal radius for using this area as an alternative intraosseous route. Methods: Contrast-enhanced MR images of 56 adult patients (28 females, 28 males) without any wrist pathology were evaluated. The shape of dorsal tubercle and its relations with neighboring tendons and vessels with a diameter larger than 2 mm was identified on the axial T1-weighted sections. The soft tissue thickness above the most protruding point of the dorsal tubercle, the distance of the dorsal tubercle to closest tendon on the radial and ulnar sides, as well as its distance to the bone edges on the ulnar and radial sides, and the cortical bone thickness of the radius was evaluated. Results: The dorsal tubercle had sharp edges in 40 cases (71.4%), blunt in 12 cases (21.4%), and hump in 4 (%7.1) cases. Branches of dorsal venous plexus were found on its surface in 11 cases, extensor pollicis longus tendon only was found superficial to the dorsal tubercle in 7 cases while both extensor pollicis longus and dorsal venous branches were found in 2 cases. Conclusion: Dorsal tubercle of the distal radius can be considered as an important alternative route for IO infusions since it can be easily accessed without having a risk of injury to important structures, and can provide effective flow.


1990 ◽  
Vol 69 (8) ◽  
pp. 1512-1518 ◽  
Author(s):  
A.G. Pullinger ◽  
F. Baldioceda ◽  
C.A. Bibb

This investigation used a histological model to study the relationship of articular soft-tissue thickness and contour to the underlying bone in the TMJ condyle of young adults. The usefulness of selected dental and demographic factors in the prediction of the articular soft-tissue thickness and contour was also tested. One sagittal histological section was studied from the lateral, central, and medial thirds of 53 left mandibular condyles. Outline tracings of the articular and compact bone surface were divided into anterior, superior, and posterior sectors for the study of curvature measured by the overlaying of a template of a harmonic series of arcs. The thickness and composition of the articular tissues were measured in each sector by light microscopy. The fibrous connective tissue layer always maintained the articular surface, even in the absence of a cartilage layer. The histological character, including the presence or absence of cartilage, rather than the overall tissue thickness, was considered to be a more useful marker of functionally stimulated changes in the joint. Articular soft-tissue thickness was not related to surface deviation in form and was not correlated with age in this young adult sample. Reduced soft-tissue thickness in the anterior part of the condyle was more common in cases with lack of molar support. Dental attrition was not a useful predictor of soft-tissue thickness. Compact bone contour correlated with soft-tissue contour in the superior (r = 0.816) and posterior (r = 0.808) sectors, explaining only 64% of the variance, but not in the anterior sector (r = 0.265). Thicker or thinner articular soft tissue was not predictable by the underlying compact bone contour or thickness. Therefore, the clinician should not automatically assume that the radiographic osseous image represents the actual articular surface.


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