Prognostic factors for surgical site infection following intramedullary nailing of diaphyseal fractures of the femur and tibia in adult patients at a tertiary hospital in Lusaka, Zambia

2021 ◽  
pp. 004947552110646
Author(s):  
Webster Musonda ◽  
Derek Freitas ◽  
Kaunda Yamba ◽  
William Jim Harrison ◽  
James Munthali
Keyword(s):  
Prognostic Factors ◽  
Surgical Site Infection ◽  
Intramedullary Nailing ◽  
Tertiary Hospital ◽  
Alternative Methods ◽  
Long Bone ◽  
Site Infection ◽  
Resource Setting ◽  
Early Return ◽  
Diaphyseal Fractures

Our study aimed to identify prognostic factors for surgical site infection following long bone fracture intramedullary nailing at a tertiary hospital in a low-resource setting. This was a longitudinal observational study involving 132 participants enrolled over a one-year period with femoral and tibial diaphyseal fractures scheduled for ORIF. Participant median age was 30 years (range: 26 – 42). The prevalence of surgical site infection was 16%. Male sex (AOR=0.26, 95% CI [0.70–0.98]; p = 0.047) was associated with lower odds of surgical site infection while associated non-musculoskeletal injuries were associated with higher odds of developing surgical site infection. Our study confirms a higher surgical site infection rate than normally accepted. However, intramedullary nailing in our setting is justified as it allows an early return to a pre-injury state. These interventions must be carried out in the best possible circumstances. Future studies could explore alternative methods of fracture fixation.

scholarly journals Inflammatory blood parameters as prognostic factors for surgical site infection after primary hip or knee arthroplasty: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e046027
Author(s):  
Petr Domecky ◽  
Anna Rejman Patkova ◽  
Katerina Mala-Ladova ◽  
Josef Maly
Keyword(s):  
Systematic Review ◽  
Prognostic Factors ◽  
Diagnostic Accuracy ◽  
Surgical Site Infection ◽  
Knee Arthroplasty ◽  
Hip Arthroplasty ◽  
Blood Parameters ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Site Infection

IntroductionSurgical site infection (SSI) is a potential complication of surgical procedure. SSI after implant surgery is a disaster both for patients and surgeons. Although predictive tools for SSI are available, none of them estimate early infection based on inflammatory blood parameters. The inflammatory process can be measured using several parameters including interleukin-6, C reactive protein, neutrophil to lymphocyte ratio, white cell count, erythrocyte sedimentation rate or procalcitonin. This systematic review aims to determine whether inflammatory blood parameters could be used as significant predictive factors for SSI after primary hip or knee arthroplasty.Methods and analysisA systematic review of randomised controlled trials, cross-sectional studies, case–control studies and cohort studies, published in English, will be searched in the following electronic bibliographic databases: MEDLINE, Embase, PubMed, Cochrane Central Register of Controlled Trials and Web of Science. Studies performed in adult patients of all ages who underwent knee or hip arthroplasty, studies containing data on the risk/prognostic factors for preknee or postknee or hip arthroplasty SSI and studies with a minimum follow-up of 30 days after surgery will be included. A standardised form will be used to extract data from the included studies comprising study characteristics, participant characteristics, details of the intervention, study methodology and outcomes. Quality Assessment of Diagnostic Accuracy tool, second version, and Standards for Reporting of Diagnostic Accuracy Studies checklist will be used to assess risk of bias. Heterogeneity will be assessed using Cochran χ² statistic and I2 statistics where applicable. Grading of Recommendations Assessment, Development and Evaluation and Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance will be used to report findings.Ethics and disseminationNo ethics approval is required. The findings will be disseminated at national and international scientific sessions, also to be published in a peer-reviewed journal.PROSPERO registration numberCRD42020147925.

scholarly journals Surgical Site Infection Post-appendectomy in a Tertiary Hospital, Jeddah, Saudi Arabia

Cureus ◽  
2021 ◽  
Author(s):  
Mohammed I Koumu ◽  
Abdulkarim Jawhari ◽  
Saleh A Alghamdi ◽  
Mutasem S Hejazi ◽  
Ali H Alturaif ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Surgical Site Infection ◽  
Tertiary Hospital ◽  
Site Infection

scholarly journals Clinical and radiological evaluation of minimally invasive intramedullary fixation by titanium elastic nails in paediatric long bone fractures of lower limb: a prospective study

2019 ◽  
Vol 5 (5) ◽  
pp. 816
Author(s):  
A. Sandeep ◽  
Jayant Jain
Keyword(s):  
Intramedullary Nailing ◽  
Complication Rate ◽  
Bone Fractures ◽  
Full Range ◽  
Elastic Stable Intramedullary Nailing ◽  
Long Bone ◽  
Ankle Motion ◽  
Soft Tissue Envelope ◽  
Internal Support ◽  
Diaphyseal Fractures

<p class="abstract"><strong>Background:</strong> Elastic stable intramedullary nailing for the treatment of paediatric femur and tibial diaphyseal fractures was introduced by Prevot and colleagues in 1979. It follows three-point fixation principle that provides internal support in presence of cortical contact and an intact soft-tissue envelope. This technique has many advantages, including better reduction, dynamic axial stabilization, shorter hospitalization with early rehabilitation and low complication rate.</p><p class="abstract"><strong>Methods:</strong> This is a prospective observational study done at Kauvery Medical Centre, Trichy between May 2017 to May 2018 consisting of 39 children between age 5 to 16 years with diaphyseal fractures of femur and tibia. The fractures were treated by closed reduction and internal fixation with titanium elastic intramedullary nailing. The patients were evaluated clinically and radiologically and followed for an average of 6 months. Outcome was assessed using transcutaneous electrical nerve stimulation (TENS) scoring system used by Flynn et al.<strong></strong></p><p class="abstract"><strong>Results:</strong> Our series consisted of 39 patients (22 cases with fracture shaft of femur and 17 cases with fracture shaft of tibia), 33 males and only 6 females. Average time for radiological union was 9.89 weeks. All patients had full range of hip and ankle motion and 2 (5.1%) patients had mild restriction in knee flexion at 12 weeks.</p><p class="abstract"><strong>Conclusions:</strong> Elastic stable intramedullary nailing is an ideal method for treatment of paediatric femoral and tibial diaphyseal fractures due to lower complication rate and good functional outcome in comparison to other methods of treatment.</p>

Wound photography for evaluation of surgical site infection and wound healing after lower limb trauma

2021 ◽  
Vol 103-B (12) ◽  
pp. 1802-1808
Author(s):  
Julie Bruce ◽  
Ruth Knight ◽  
Nick Parsons ◽  
Ria Betteridge ◽  
Amy Verdon ◽  
...  
Keyword(s):  
Wound Healing ◽  
Surgical Site Infection ◽  
Clinical Assessment ◽  
Lower Limb ◽  
Open Fracture ◽  
Alternative Methods ◽  
Site Infection ◽  
Limb Fracture ◽  
Wound Photography ◽  
Level Of Agreement

Aims Deep surgical site infection (SSI) is common after lower limb fracture. We compared the diagnosis of deep SSI using alternative methods of data collection and examined the agreement of clinical photography and in-person clinical assessment by the Centers for Disease Control and Prevention (CDC) criteria after lower limb fracture surgery. Methods Data from two large, UK-based multicentre randomized controlled major trauma trials investigating SSI and wound healing after surgical repair of open lower limb fractures that could not be primarily closed (UK WOLLF), and surgical incisions for fractures that were primarily closed (UK WHiST), were examined. Trial interventions were standard wound care management and negative pressure wound therapy after initial surgical debridement. Wound outcomes were collected from 30 days to six weeks. We compared the level of agreement between wound photography and clinical assessment of CDC-defined SSI. We are also assessed the level of agreement between blinded independent assessors of the photographs. Results Rates of CDC-defined deep SSI were 7.6% (35/460) after open fracture and 6.3% (95/1519) after closed incisional repair. Photographs were obtained for 77% and 73% of WOLLF and WHiST cohorts respectively (all participants n = 1,478). Agreement between photographic-SSI and CDC-SSI was fair for open fracture wounds (83%; k = 0.27 (95% confidence interval (CI) 0.14 to 0.42)) and for closed incisional wounds (88%; k = 0.29 (95% CI 0.20 to 0.37)) although the rate of photographically detected deep SSIs was twice as high as CDC-SSI (12% vs 6%). Agreement between different assessors for photographic-SSI (WOLLF 88%, k = 0.63 (95% CI 0.52 to 0.72); WHiST 89%; k = 0.61 (95% CI 0.54 to 0.69)); and wound healing was good (WOLLF 90%; k = 0.80 (95% CI 0.73 to 0.86); WHiST 87%; k = 0.57 (95% CI 0.50 to 0.64)). Conclusion Although wound photography was feasible within the research context and inter-rater assessor agreement substantial, digital photographs used in isolation overestimated deep SSI rates, when compared to CDC criteria. Wound photography should not replace clinical assessment in pragmatic trials but may be useful for screening purposes where surgical infection outcomes are paramount. Cite this article: Bone Joint J 2021;103-B(12):1802–1808.

Mucor as a cause of surgical site infection

2020 ◽  
Vol 50 (3) ◽  
pp. 249-251
Author(s):  
Ravikanta Negi ◽  
Robin Kaushik ◽  
Simrandeep Singh ◽  
Rajpal Singh Punia
Keyword(s):  
Surgical Site Infection ◽  
Intramedullary Nailing ◽  
Site Infection

Mucor is an uncommon cause of surgical site infection. We present such a case after intramedullary nailing of the femur and discuss its presentation and management.

Trends in the incidence of superficial versus deep-organ/space surgical site infection in a tertiary hospital

2013 ◽  
Vol 184 (2) ◽  
pp. 1085-1091 ◽  
Author(s):  
Rafael Herruzo ◽  
Jesus Diez-Sebastián ◽  
Eduardo Mora ◽  
Juan Garcia-Caballero
Keyword(s):  
Surgical Site Infection ◽  
Tertiary Hospital ◽  
Site Infection

Does Wound Management Technique Impact Surgical Site Infection in Open Emergency Colon Procedures?

2020 ◽  
pp. 000313482098256
Author(s):  
Justin J. Turcotte ◽  
Andrea Boord ◽  
Lauren Antognoli ◽  
J. Robert Klune ◽  
Cristina B. Feather
Keyword(s):  
Length Of Stay ◽  
Surgical Site Infection ◽  
Alternative Methods ◽  
Wound Management ◽  
Secondary Outcome ◽  
Management Technique ◽  
Site Infection ◽  
Vac Therapy ◽  
Significant Difference ◽  
Care Surgery

Background Emergency open large bowel procedures have higher rates of intraoperative contamination and increased risk of surgical site infection (SSI) than elective colon surgeries. Several wound management strategies have been proposed, such as vacuum-assisted closure (VAC) therapy and delayed primary closure to improve results. The purpose of this study is to evaluate the relationship between wound management technique and SSI and other quality measures. Methods We performed a retrospective review of patients undergoing open emergency colon surgery from January 2017 to December 2018 by our acute care surgery service. The primary outcome measure was incidence of SSI. Secondary outcome measures included length of stay, reoperation, and 30-day readmission. Results A total of 118 patients were included in the study, with a mean age of 62.8 years and mean BMI of 28.8. Overall incidence of SSI was 19.5%. There was no significant difference in incidence of SSI, reoperation, or 30-day readmission when stratifying by wound management technique or procedure type after controlling for confounding variables. Notably, patients managed with VAC therapy had a statistically significant longer average length of stay and higher total postoperative antibiotic days (both P = .001) than other techniques. Discussion We conclude from our data that wound management technique does not seem to influence rate of SSI, but wound management may influence length of stay or antibiotic duration. These findings suggest that there may not be an advantage to alternative methods of wound management in this high-risk population. Further prospective evaluation should be performed to confirm these findings.

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