AIDS in Africa: What Drugs do the Carers Want or Need?

1996 ◽  
Vol 26 (2) ◽  
pp. 72-76 ◽  
Author(s):  
A C Lamont ◽  
M Greiff ◽  
D S Rosenberg ◽  
T R Wiggin

Our objectives were: (1) to discover requirements for treatment of patients with AIDS (PWAs) for healthcare workers in eight English-speaking African countries; (2) to establish policies for supply of drugs, and develop a method for determining the contents of parcels (PWA-BOXes) for the relief of PWAs. Fifty-seven questionnaires were sent to non-government medical units treating PWAs, supplied by the charity Inter Care. Of these 37 units replied, two had no known PWAs, three were swamped by refugees; therefore, the total number analysed was 32. Only 24 units had access to HIV testing and the mean number of PWAs per unit was 58. The reported complications of AIDS were: diarrhoea 28 units; tuberculosis 27 units; pneumonia 28 units; sexually transmitted diseases 26; candidiasis 28 units; and herpes zoster 20. Lists of drug requirements were received. We present a protocol for calculation of contents of PWA-BOXes in the hope that this will provide guidelines for other workers in this field.

1994 ◽  
Vol 1 (5) ◽  
pp. 216-219
Author(s):  
Lisa N. Gittens ◽  
Rhonda R. Nichols ◽  
Joseph J. Apuzzio

Objective: The purpose of this study was to determine the epidemiology of sexually transmitted diseases (STDs) among pregnant adolescents.Methods: Charts of all patients (n = 735) who attended the Maternal and Infant Care Clinic at University Hospital, Newark, NJ, between July 1, 1991, and June 30, 1992, were reviewed for STDs which included gonorrhea, chlamydia, syphilis, and human immunodeficiency virus (HIV). At the first prenatal visit, each registrant had endocervical specimens obtained to detect gonorrhea and chlamydia. A serum sample was obtained for syphilis screening. HIV testing was made available to all patients and testing was done on a voluntary basis. The same STD screening that was done at the initial visit was repeated at 28 and 36 weeks.Results: Twenty-five percent of patients tested positive for one or more STDs. The mean patient age was 17.3 years. The mean gestational age at first visit was 19.5 weeks. The mean number of visits was 7.3. The following STDs were identified: 4.8% of patients tested positive for gonorrhea, 20.9% tested positive for chlamydia, and 1.7% tested positive for syphilis. Twenty-one percent of patients had a positive STD diagnosed at the initial visit. Another 4.8% of patients had an STD diagnosed at some time after the initial visit when the initial screen was negative for STDs. An additional 1% of patients who initially tested positive for an STD had subsequent screening which revealed another STD (different organism). Seven patients tested HIV positive. Sixty-one percent of patients with STDs agreed to HIV testing. One patient had HIV coexistent with another STD.Conclusions: Pregnant adolescents are at risk for multiple STDs. HIV testing should be offered. STD screening should be repeated in the third trimester in adolescent patients.


1996 ◽  
Vol 72 (5) ◽  
pp. 347-351
Author(s):  
S Madge ◽  
J Elford ◽  
M C Lipman ◽  
J Mintz ◽  
M A Johnson

BMJ ◽  
1987 ◽  
Vol 295 (6591) ◽  
pp. 191-193 ◽  
Author(s):  
E J Beck ◽  
D G Cunningham ◽  
V W Moss ◽  
J R Harris ◽  
A J Pinching ◽  
...  

2002 ◽  
Vol 6 (20) ◽  
Author(s):  
C McGarrigle

The United States (US) Centers for Disease Control and Prevention has published new guidelines for the treatment of sexually transmitted diseases (STDs) (1). The guidelines are for physicians and other healthcare providers who prevent and treat sexually transmitted diseases (STDs).


2019 ◽  
Vol 73 ◽  
pp. 294-302
Author(s):  
Kamila Wójcik-Cichy ◽  
Anna Piekarska ◽  
Elżbieta Jabłonowska

Early diagnosis increases life expectancy in HIV-infected patients. Aim: The aim of this study was to determine the reasons for HIV testing in newly-diagnosed patients with HIV registered in Lodz, Poland in years 2009-2017. The study examines also whether HIV testing was performed following the recommendation of physicians or at the request of patients. Results: The study group consisted of 401 (83.72%) males and 78 (16.28%) females. The median age at the moment of diagnosis was 33 years (LQ 27-UQ 40). In total, 285 (62.91%) patients were late presenters. Clinical indications constituted the main reason for undergoing HIV testing and were reported in 228 out of 479 patients (47.59%) including AIDS-defining diseases were a reason for HIV testing in 105 patients. Thirty-four patients underwent HIV testing following diagnosis of sexually-transmitted diseases (STDs); in 91.18% of these cases the STDs was syphilis. However, high-risk sexual contact was the main reason for HIV testing in asymptomatic patients (160 of 257 cases; 62.27%). Patients in the non-AIDS group were significantly more likely to take the initiative to order an HIV test than patients in the AIDS group (p<0.0001). Conclusions: In conclusion, in the Lodz region, patients with HIV infection are most commonly diagnosed at an advanced stage of infection. This may be associated with the low number of HIV tests performed following the doctors recommendation.


1988 ◽  
Vol 9 (5) ◽  
pp. 200-203 ◽  
Author(s):  
Philippe Lepage ◽  
Philippe Van de Perre

AbstractWe reviewed the published data on the possible impact of medical injections and blood transfusions on the spread of human immunodeficiency virus (HIV) in Africa. We also compared these results to our experience in Rwanda, central Africa. The importance of medical injections in the epidemic of HIV infection seems to differ from one area to another. The excess of injections experienced by HIV seropositive subjects in Zaire could be secondary to the parenteral treatment of early HIV-related illness or to the treatment of sexually transmitted diseases, rather than being the cause of HIV infection, as suggested by Rwandese studies. In contrast, blood transfusions have been shown to represent an important source of nosocomial HIV infection in many African countries. Effective and relatively inexpensive measures to diminish the iatrogenic spread of HIV infection in developing countries are summarized.


2021 ◽  
Vol 141 (5) ◽  
pp. 46-52
Author(s):  
Nguyen Hoai Bac ◽  
Hoang Long

Sexually transmitted diseases (STDs) have been a public health issue in many developing countries, especially in Vietnam. Unsafe sex is considered to be one of the main causes to increase infected person. Therefore, we conducted a study on 3005 men who presented to the Andrology and Sexual Medicine Units of Hanoi Medical University Hospital to analyze the correlation between sexual behaviors and sexually transmitted diseases in men. The result showed that the mean age at first sex (AFS) was 21 years old. The median number of stable sexual partners was 2, the overall rate of STDs was 9.95%, in particular, the proportion of STDs in single men was higher than the married group (11.8% and 7.5%, p < 0.001), men having first intercourse before 25 years old had the rate of STDs was higher compared with their counterpart (21.1% vs. 13.2%, p = 0.002). Subjects with multiple unstable sexual partners were 2.11 times more likely to be infected with STDs, and the risk of infecting STDs would rise 6% for each additional sex partner.


Afrika Focus ◽  
1990 ◽  
Vol 6 (1) ◽  
Author(s):  
Antoon De Schryver ◽  
André Meheus

Sexually transmitted diseases (STD) are defined as a group of communicable diseases which have in common that they are transmitted predominantly by sexual contact. The number of agents now known to be sexually transmitted include some 20 pathogens. Some of these agents (such as Chlamydia trachomatis, herpes simplex virus, human papilloma virus, hepatitis B. virus, human immunodeficiency virus) tend to replace the classical "venereal diseases" both in importance and frequency as these agents are often more difficult to detect, treat, and control. Sexually transmitted diseases are a major public health problem in most African countries on account of their frequency, their associated morbidity and mortality, their impact on maternal and infant health, as well as their economic costs in terms of health expenditure and lost productivity, and, last but not least, because of their social consequences. Recent epidemiological studies using sophisticated diagnostic technologies greatly extend our knowledge on the true spectrum of complications and sequelae associated with these infections. Nongonococcal urethritis - caused to 40% by Chlamydia trachomatis - and gonococcal infections are together the most frequent sexually transmitted diseases. The increasing importance of chlamydial infections, in contrast to a gradual decrease of gonococcal infections, is related to the fact that these infections Sexually transmitted diseases (STD) are defined as a group of communica- ble diseases which have in common that they are transmitted predominantly by sexual contact. The number of agents now known to be sexually trans- mitted include some 20 pathogens. Some of these agents (such as Chlamydia trachomatis, herpes simplex virus, human papilloma virus, hepatitis Br virus, human immunodeficiency virus) tend to replace the classical "vene- real diseases" both in importance and frequency as these agents are often more difficult to detect, treat, and control. Sexually transmitted diseases are a major public health problem in most African countries on account of their frequency, their associated morbidity and mortality, their impact on maternal and infant health, as well as their economic costs in terms of health expenditure and lost productivity, and, last but not least, because of their social consequences. Recent epidemio- logical studies using sophisticated diagnostic technologies greatly extend our knowledge on the true spectrum of complications and sequelae asso- ciated with these infections. Nongonococcal urethritis - caused to 40% by Chlamydia trachomatis - and gonococcal infections are together the most frequent sexually transmitted diseases. The increasing importance of chlamydial infections, in contrast to a gradual decrease of gonococcal infections, is related to thefact that these infections frequently cause asymptomatic or mild disease and do not motivate patients to seek medical care, resulting in an extended period of infectivity and high risk of developing complications. Untreated gonorrhoea and chlamydial infections are the most common causes of epididymitis in males under the age of 35 years and may lead to decreased fertility. In some parts of sub-saharan Africa where urethritis often goes untreated, epididymitis is the leading course of male infertility. Also urethral strictures still from a large part of urogenital practice in some African countries. An estimated 8-16% of women with untreated endocervical gonococcal or chlamydial infections will develop acute salpingitis following an ascending spread of these pathogens. After one episode of acute salpingitis approximately 10% of women may become infertile due to complete tubal occlusion. Similarly, the risk for women to develop an ectopic pregnancy after salpingitis is 6-10 times greater than in controls. Ectopic pregnancies in areas with insufficient health services carry a high mortality risk. Maternal infections with STD may not only have adverse effects on pregnancy outcome but may cause serious morbidity and mortality in the newborn (e.g. congenital syphilis, ophthalmia neonatorum, herpes simplex virus infection of the neonate, chlamydial pneumonia, congenital HIV infection). AIDS is an example "par excellence" of a sexually transmitted disease of public health importance requiring extensive clinical services and posing enormous financial and social problems for the individual and the society at large. AIDS and the other viral STD have greatly increased the interest in primary prevention strategies such as health education and behavioral modification, for the control of sexually transmitted diseases.KEYWORDS: chancroid, chlamydia, gonorrhoea, HIV, infertility, sexually transmitted diseases, surveillance 


2019 ◽  
Vol 73 ◽  
pp. 1-10
Author(s):  
Kamila Wójcik-Cichy ◽  
Anna Piekarska ◽  
Elżbieta Jabłonowska

Early diagnosis increases life expectancy in HIV-infected patients. Aims: The aim of this study was to determine the reasons for HIV testing in newly-diagnosed patients with HIV registered in Lodz, Poland in years 2009-2017. The study examines also whether HIV testing was performed following the recommendation of physicians or at the request of patients. Results: The study group consisted of 401 (83.72%) males and 78 (16.28%) females. The median age at the moment of diagnosis was 33 years (LQ 27-UQ 40). In total, 285 (62.91%) patients were late presenters. Clinical indications constituted the main reason for undergoing HIV testing and were reported in 228 out of 479 patients (47.59%) including AIDS-defining diseases were a reason for HIV testing in 105 patients. Thirty-four patients underwent HIV testing following diagnosis of sexually-transmitted diseases (STDs); in 91.18% of these cases the STDs was syphilis. However, high-risk sexual contact was the main reason for HIV testing in asymptomatic patients (160 of 257 cases; 62.27%). Patients in the non-AIDS group were significantly more likely to take the initiative to order an HIV test than patients in the AIDS group (p<0.0001). Conclusions: In conclusion, in the Lodz region, patients with HIV infection are most commonly diagnosed at an advanced stage of infection. This may be associated with the low number of HIV tests performed following the doctors recommendation.


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