scholarly journals The Effect of Nitrous Oxide on the Outcomes of Underlay Tympanoplasty: A Prospective Study

2019 ◽  
Vol 98 (10) ◽  
pp. 621-624
Author(s):  
Ufuk Düzenli ◽  
Nazım Bozan ◽  
Mahfuz Turan ◽  
Semra Ağırbaş ◽  
Arzu Esen Tekeli ◽  
...  
Keyword(s):  
Nitrous Oxide ◽  
Postoperative Pain ◽  
Prospective Study ◽  
Middle Ear ◽  
Anesthetic Agent ◽  
Success Rates ◽  
Middle Ear Pressure ◽  
The Difference ◽  
Graft Success ◽  
A Prospective Study

The main aims of tympanoplasty are eradication of chronic middle ear disease, repair of the tympanic membrane, and restoration of hearing. Nitrous oxide (N2O) is not a commonly preferred anesthetic agent for tympanoplasty because this agent may increase middle ear pressure and displace the graft. In this study, we researched the surgical outcomes of the underlay tympanoplasty performed with N2O anesthesia. Patients who underwent tympanoplasty were included in this prospective study. A type 1 tympanoplasty was performed in all patients using the underlay technique. Patients were randomized to groups that did and did not receive N2O. Preoperative and postoperative hearing thresholds were evaluated, postoperative pain scores were recorded, and the differences between the groups were statistically evaluated. There were 44 patients who received N2O and 44 who did not. The graft success rate was 93.2% in the N2O-receiving group and 84.1% in the nonreceiving group ( P > .05). Hearing levels improved significantly after surgery in each group ( P < .05), but the difference between the groups was not significant ( P > .05). The postoperative pain score was 3.72 ± 1.3 in the N2O-receiving group and 4.45 ± 2.3 in the nonreceiving group ( P > .05). Nitrous oxide is a cheap, safe, and readily available anesthetic agent that provides acceptable success rates in patients undergoing tympanoplasty.

scholarly journals Is Allergic Rhinitis a Factor That Affects Success of Tympanoplasty?

2016 ◽  
Vol 59 (1) ◽  
pp. 10-13
Author(s):  
Elif Ersoy Callioglu ◽  
A. Sami Bercin ◽  
Hayati Kale ◽  
Togay Muderris ◽  
Sule Demirci ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Success Rate ◽  
Middle Ear ◽  
Success Rates ◽  
Type 1 Tympanoplasty ◽  
Significant Difference ◽  
Patient Groups ◽  
The Difference ◽  
Graft Success

Objective: The aim of the present study was to investigate the effect of allergic rhinitis on the success of the operation in chronic otitis surgery by using score for allergic rhinitis (SFAR). Materials and Methods: In the present study; 121 patients, who underwent type 1 tympanoplasty were examined retrospectively. SFAR of all patients were recorded. The graft success rates of 26 patients with allergic rhinitis (AR) and 95 patients with no allergic rhinitis group (NAR) were compared. Results: While the graft success rate in NAR group was 89.5%, this rate was 80.8% in the AR group. However, the difference between groups was not statistically significant (p = 0.311). Conclusion: These findings suggest that allergic rhinitis decreases the graft success rate of the pathologies occurring in eustachian tube, middle ear and mastoid although statistically significant difference wasn’t found. Prospective studies with larger patient groups are required in order to evaluate this pathology.

“EFFECT OF ANTERIOR NASAL PACKING ON MIDDLE EAR FUNCTION AND HEARING: A PROSPECTIVE STUDY”

2020 ◽  
Vol VOLUME 8 (ISSUE 1) ◽  
pp. 9-14
Author(s):  
Sachin Jain
Keyword(s):  
Prospective Study ◽  
Key Words ◽  
Tympanic Membrane ◽  
Eustachian Tube ◽  
Middle Ear ◽  
Hearing Threshold ◽  
Nasal Packing ◽  
Middle Ear Pressure ◽  
A Prospective Study

Introduction- The Eustachian tube provides an anatomic communication between the middle ear and nasopharynx, and maintains pressure equality across the tympanic membrane. Objective- To see the effect of anterior nasal packing on Otological symptoms, middle ear pressure and hearing Materials and method- This prospective study was carried out during period of September 2018 till August 2019. 100 ears were taken in the study. Middle ear pressure and hearing threshold were evaluated by Tympanometry and Audiometry respectively. Results- Postoperatively two days after anterior nasal packing, there was increase in no. of patient ears with ear fullness, ear ache, tinnitus, hearing threshold and abnormal negative middle ear pressure. After removal of nasal packing up to twelve weeks, improvement in middle ear pressure and hearing threshold was seen. Conclusion- Anterior nasal packing causes decrease in middle ear pressure and increase in hearing threshold. Key words- Eustachian tube, Middle ear pressure, Hearing threshold

scholarly journals Differences in Total Score of Positive and Negative Syndrome Scale between Bataknese and Javanese Men with Schizophrenia Receiving Risperidone Treatment

2019 ◽  
Vol 7 (14) ◽  
pp. 2292-2297
Author(s):  
Manahap Verarius F. Pardosi ◽  
Bahagia Loebis ◽  
Muhammad Surya Husada ◽  
Nazli M. Nasution ◽  
Elmeida Effendy ◽  
...  
Keyword(s):  
Prospective Study ◽  
Difference Score ◽  
Social Classes ◽  
Average Score ◽  
Syndrome Scale ◽  
The Difference ◽  
The Individual ◽  
A Prospective Study ◽  
Negative Syndrome ◽  
Risperidone Treatment

BACKGROUND: Schizophrenia is a psychopathological syndrome clinic involving cognition, emotion, perception and other aspects from the individual which interferences. This interference is normally started before age 25, and it can affect all social classes. AIM: To find out the difference in total positive and negative syndrome scale (PANSS) scores in schizophrenia between Bataknese and Javanese who have received treatment with risperidone. METHODS: This study is a prospective study. This study used numeric comparative analytic two unpaired groups to observe the differences of PANSS score of the man with schizophrenia between Bataknese and Javanese who had received risperidone treatment. RESULTS: Our study found that the average score of PANSS for Bataknese was 49.76 ± 12.65 and Javanese was 42.43 ± 9.05. CONCLUSION: There was a difference score of PANSS for the man with schizophrenia between Bataknese and Javanese who had received risperidone treatment for 6 weeks (p = 0.037).

scholarly journals Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status – a prospective study

2020 ◽  
Vol 134 (8) ◽  
pp. 717-720 ◽  
Author(s):  
MH Hussain ◽  
M Mair ◽  
P Rea
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Prospective Study ◽  
Control Group ◽  
Study Group ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
The Mean ◽  
Polymerase Chain ◽  
The Difference ◽  
A Prospective Study

AbstractObjectiveTo evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.MethodsA prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.ResultsThe mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).ConclusionEpistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.

scholarly journals Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus

Viruses ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1392
Author(s):  
Ignacio Parrón ◽  
Irene Barrabeig ◽  
Miquel Alseda ◽  
Thais Cornejo-Sánchez ◽  
Susana Guix ◽  
...  
Keyword(s):  
Prospective Study ◽  
Confidence Intervals ◽  
Personal Hygiene ◽  
Occupational Category ◽  
Hygiene Measures ◽  
The Mean ◽  
The Difference ◽  
Rate Ratios ◽  
A Prospective Study ◽  
Mean Cycle

Norovirus outbreaks frequently occur in closed or semiclosed institutions. Recent studies in Catalonia and various countries indicate that, during outbreaks in these institutions, norovirus is detected in between 23% and 60% of workers, and the prevalence of infection in asymptomatic workers involved in outbreaks ranges from 17% to 40%. In this work, we carried out a prospective study to investigate the involvement of workers in closed and semiclosed institutions during outbreaks. The attack rates (ARs) and the rate ratios (RRs) were calculated according to the type of transmission and occupational category. The RRs and 95% confidence intervals (CIs) between workers and users were calculated. The mean cycle of quantification (Cq) values were compared according to the genogroup and the presence of symptoms. ARs were higher in person-to-person transmission than in common vehicle outbreaks, and 38.8% of workers were symptomatic. The RR between workers and users was 0.46 (95% CI 0.41–0.52). The ARs in workers were high, particularly in workers with closer contact with users. The mean Cq was lower in patients than in asymptomatic infected persons, although the difference was only significant for genogroup I (GI). The frequency of asymptomatic infected persons suggests that personal hygiene measures should be followed by all workers in the centers affected.

The acquisition of Mycobacterium tuberculosis infection in village doctors in China: a prospective study

2020 ◽  
Vol 24 (12) ◽  
pp. 1241-1246
Author(s):  
H. Zhang ◽  
X. Cao ◽  
D. Wang ◽  
H. Xin ◽  
Z. Liu ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Prospective Study ◽  
Mycobacterium Tuberculosis Infection ◽  
Pulmonary Tb ◽  
Village Doctors ◽  
Key Population ◽  
Related Risk ◽  
The Difference ◽  
A Prospective Study

BACKGROUND: Occupational exposure-related risk of Mycobacterium tuberculosis infection has been reported for village doctors in China. This prospective study aims to estimate the infection acquisition in this key population.METHODS: At baseline, all village doctors registered in Zhongmu County were tested by QuantiFERON®-TB Gold In-Tube (QFT) and QuantiFERON®-TB Gold Plus (QFT-Plus) in parallel. Those negatives for either of the tests were retested to identify conversions at the 2-year follow-up investigation.RESULTS: A total of 367 eligible participants completed the 2-year follow-up survey with frequency of conversion of 5.0% (18/361) for QFT and 6.1% (21/343) for QFT-Plus. The agreement of follow-up results between the tests was 93.2% with a κ coefficient of 0.43 (95%CI 0.20–0.65). Among QFT-Plus convertors, the difference between TB1 and TB2 tubes (TB2-TB1) was significantly increased as compared with baseline results (P = 0.039). Participants from the villages with occurrence of microbiologically confirmed pulmonary TB showed higher frequency of QFT conversions (11.0% vs. 3.2%, P = 0.011) and QFT-Plus conversions (12.3% vs. 4.4%, P = 0.027) than those from the villages without occurrence.CONCLUSION: Our results consistently suggest that capability on occupational protection and M. tuberculosis infection control should be improved in village doctors in China.

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