scholarly journals Vestibular Function in Psoriasis Patients

2020 ◽  
pp. 014556132097068
Author(s):  
Abdullah Kınar ◽  
Abdulkadir Bucak ◽  
Şahin Ulu ◽  
Nilay Duman ◽  
Nur Betül Baştuğ
Keyword(s):  
Vestibular System ◽  
Inflammatory Disease ◽  
Vestibular Function ◽  
Control Group ◽  
Distortion Product Otoacoustic Emission ◽  
Duration Of Treatment ◽  
Vestibular Evoked Myogenic Potential ◽  
Cross Sectional ◽  
Distortion Product ◽  
Immune Mediated

Introduction: Psoriasis is an inflammatory skin disease that is characterized by T-cell-mediated hyperproliferation of the keratinocytes. It develops through immune-mediated mechanisms and is defined as an immune-mediated inflammatory disease. The inner ear is susceptible to inflammatory attacks, and vertigo and dizziness can occur as a complication. There is little information about psoriasis and the vestibular system. Objective: This study aimed to investigate the cervical vestibular-evoked myogenic potential (cVEMP) results of psoriasis patients and the effect of psoriasis on the vestibular system. Materials and Methods: Randomly selected and included in the study were patients who had been admitted to the Dermatology Outpatient Clinic of the Afyon Kocatepe University Medical Faculty, between November 15, 2017, and March 15, 2018, with the diagnosis of psoriasis, in addition to a healthy control group. This research was designed as cross-sectional study. Ethics committee permission was received. Both cVEMP and distortion product otoacoustic emission (DPOAE) tests were administered to all of the participants. Values were compared between the control group and psoriasis patients. Results: The study included 43 psoriasis patients and 40 controls. The duration of treatment of the patients and the drugs that they were using were noted. The psoriasis patients had lower p13–n23 amplitude differences in their cVEMP tests ( P < .05). These patients also had lower signal to noise ratio values, at 4 and 6 kHz, on their DPOAE tests ( P < .05). Conclusion: Psoriasis is an immune-mediated inflammatory disease that can be associated with vestibulocochlear dysfunction.

scholarly journals Cochlear And Vestibular Involvement In Children With Henoch Schönlein Vasculitis

2021 ◽  
Author(s):  
Abdulkadir Bucak ◽  
Ayşegül Bükülmez ◽  
Selcuk Kuzu ◽  
Çağlar Günebakan ◽  
Erkan Yıldız ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Otoacoustic Emissions ◽  
Vestibular Function ◽  
Tertiary Hospital ◽  
Control Group ◽  
Healthy Children ◽  
Vestibular Evoked Myogenic Potential ◽  
Distortion Product ◽  
Significant Difference ◽  
And Control

Abstract Purpose: In this study, our purpose is to evaluate cochlear and vestibular function in juveniles with HSV using audiometry, DPOAEs, and cVEMP tests.Methods: 40 children diagnosed with HSV from the pediatry clinic and 40 age and sex-matched healthy children were evaluated with distortion product otoacoustic emissions, audiometry, and cervical vestibular evoked myogenic potential (cVEMP) test in a tertiary hospital.Results: The audiometry average values ​​for both ears of HSV group and the control subjects were compared, and as a result, median 4.7 dB sensorineural hearing loss (SHL) was found for HSV group compared to control group at 250 Hz and it was statistically significant (p <0.001). An average of 6.4 dB SHL was detected at 8000 Hz (p <0.001). There was a statistically significant difference among HSV and control group regarding measurement results of average p1-n1 latency time of both ears (0.9 milliseconds (ms) increase, P = 0.035). In HSV patients, the median amplitude difference of both ears' average p1 n1 was found to be 5,6 millivolt, statistically significantly decreased compared to the control group (p = 0.003).Conclusion: This study, firstly in literature, demonstrated that HSV may cause hearing loss and vestibular dysfunction in children. We think this might be due to autoimmune mechanisms.

Wideband Absorbance in Young Infants (0–6 months): A Cross-Sectional Study

2014 ◽  
Vol 25 (05) ◽  
pp. 471-481 ◽  
Author(s):  
Sreedevi Aithal ◽  
Joseph Kei ◽  
Carlie Driscoll
Keyword(s):  
Mixed Model ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Distortion Product Otoacoustic Emission ◽  
Sectional Study ◽  
Cross Sectional ◽  
Distortion Product ◽  
Young Infants ◽  
Developmental Effects ◽  
Data Points

Background: Wideband acoustic immittance (WAI) studies on infants have shown changes in WAI measures with age. These changes are attributed, at least in part, to developmental effects. However, developmental effects in young infants (0–6 mo) on WAI have not been systematically investigated. Purpose: The objective of this study was to compare wideband absorbance (WBA) in healthy neonates and infants aged 1, 2, 4, and 6 mo. Research Design: This was a prospective cross-sectional study. All participants were assessed by using 1-kHz tympanometry, distortion product otoacoustic emission (DPOAE) tests, and WBA tests. Study Sample: Participants included 35 newborns (35 ears), 16 infants aged 1 mo (29 ears), 16 infants aged 2 mo (29 ears), 15 infants aged 4 mo (28 ears), and 14 infants aged 6 mo (27 ears). For each participant, the ears that passed both high-frequency (1-kHz) tympanometry and DPOAE tests were included for analysis. Data Collection and Analysis: WBA was recorded at ambient pressure conditions, and the response consisted of 16 data points at 1/3-octave frequencies from 0.25 to 8 kHz. A mixed-model analysis of variance (ANOVA) was applied to the data in each age group to evaluate the effects of sex, ear, and frequency on WBA. WBA was compared between various age groups. In addition, a separate mixed-model ANOVA was applied to WBA data, and post hoc analyses with the Bonferroni correction were performed at each of the 16 data points at 1/3-octave frequencies across age groups to examine the effect of age on WBA. Results: For all age groups, WBA was highest between 1.5 and 5 kHz and lowest at frequencies of less than 1.5 kHz and greater than 5 kHz. A developmental trend was evident, with both the 0- and 6-mo-old infants being significantly different from other age groups at most frequencies. The WBA results exhibited a multipeaked pattern for infants aged 0 to 2 mo, whereas a single broad peaked pattern for 4- and 6-mo-old infants was observed. The difference in WBA between 0- and 6-mo-old infants was statistically significant across most frequencies. In contrast, the WBA results for 1- and 2-mo-old infants were comparable. There were no significant sex or ear effects on WBA for all age groups. Conclusions: Developmental effects of WBA were evident for infants during the first 6 mo of life. The WBA data can be used as a reference for detecting disorders in the sound-conductive pathways (outer and middle ear) in young infants. Further development of age-specific normative WBA data in young infants is warranted.

Does Oral Monosodium Glutamate Have a Cochleotoxic Effect? An Experimental Study

2021 ◽  
pp. 1-13
Author(s):  
Selis Gulseven Guven ◽  
Onur Ersoy ◽  
Ruhan Deniz Topuz ◽  
Erdoğan Bulut ◽  
Gulnur Kizilay ◽  
...  
Keyword(s):  
Guinea Pigs ◽  
Outer Hair Cell ◽  
Monosodium Glutamate ◽  
Auditory Brainstem ◽  
Outer Hair Cells ◽  
Control Group ◽  
Distortion Product Otoacoustic Emission ◽  
Distortion Product ◽  
Significant Difference ◽  
Brainstem Response

<b><i>Introduction:</i></b> The effect of orally consumed monosodium glutamate (MSG), which is a common additive in the food industry, on the cochlea has not been investigated. The present study aimed to investigate the possible cochleotoxic effects of oral MSG in guinea pigs using electrophysiological, biochemical, and histopathological methods. <b><i>Methods:</i></b> Thirty guinea pigs were equally divided into control and intervention groups (MSG 100 mg/kg/day; MSG 300 mg/kg/day). At 1 month, 5 guinea pigs from each group were sacrificed; the rest were observed for another month. Electrophysiological measurements (distortion product otoacoustic emission [DPOAE] and auditory brainstem response [ABR]), glutamate levels in the perilymph and blood samples, and histopathological examinations were evaluated at 1 and 2 months. <b><i>Results:</i></b> Change in signal-to-noise ratio at 2 months was significantly different in the MSG 300 group at 0.75 kHz and 2 kHz (<i>p</i> = 0.013 and <i>p</i> = 0.044, respectively). There was no statistically significant difference in ABR wave latencies of the guinea pigs given MSG compared to the control group after 1 and 2 months; an increase was noted in ABR thresholds, although the difference was not statistically significant. In the MSG groups, moderate-to-severe degeneration and cell loss in outer hair cells, support cells, and spiral ganglia, lateral surface junction irregularities, adhesions in stereocilia, and partial loss of outer hair cell stereocilia were noted. <b><i>Conclusion:</i></b> MSG, administered in guinea pigs at a commonly utilized quantity and route of administration in humans, may be cochleotoxic.

Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

2019 ◽  
Vol 133 (11) ◽  
pp. 995-1004
Author(s):  
S I Kirubaharane ◽  
S Palani ◽  
A Alexander ◽  
A Sreenivasan
Keyword(s):  
Otitis Media ◽  
Otoacoustic Emissions ◽  
Otoacoustic Emission ◽  
Chronic Suppurative Otitis Media ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Clinical Group ◽  
Distortion Product Otoacoustic Emission ◽  
Suppurative Otitis Media ◽  
Distortion Product

AbstractBackgroundDetection and valid measurements of distortion product otoacoustic emissions are not influenced by cochlear status alone, but also by middle-ear status. There is a need to understand the use of ultra-high frequency distortion product otoacoustic emissions in cases of abnormal distortion product otoacoustic emission findings for conventional frequencies related to the middle-ear condition.MethodThe present study investigated distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies in: 37 adults with chronic suppurative otitis media (clinical group) and 37 adults with normal hearing sensitivity (control group).ResultsThere were significant reductions in distortion product otoacoustic emission amplitude and mean signal-to-noise ratio in the clinical group compared to the control group, especially for conventional frequencies.ConclusionThere was a significant reduction in the rate of ears with measurable distortion product otoacoustic emissions in the clinical group, especially for conventional frequencies. The effect of chronic suppurative otitis media was more pronounced in the conventional frequency range compared to the smaller effect seen in the ultra-high frequency range.

Thymoquinone treatment for inner-ear acoustic trauma in rats

2015 ◽  
Vol 129 (1) ◽  
pp. 38-45 ◽  
Author(s):  
F Aksoy ◽  
R Dogan ◽  
A Yenigun ◽  
B Veyseller ◽  
O Ozturan ◽  
...  
Keyword(s):  
Otoacoustic Emission ◽  
Auditory Brainstem ◽  
Acoustic Trauma ◽  
Control Group ◽  
Distortion Product Otoacoustic Emission ◽  
Distortion Product ◽  
Brainstem Response ◽  
Group 3 ◽  
Group 2 ◽  
Trauma Group

AbstractObjective:To investigate whether thymoquinone has any eliminative effects against inner-ear damage caused by acoustic trauma.Methods:Thirty-two male rats were divided into four groups. Group 1 was only exposed to acoustic trauma. Group 2 was given thymoquinone 24 hours before acoustic trauma and continued to receive it for 10 days after the trauma. Group 3 was only treated with thymoquinone, for 10 days. Group 4, the control group, suffered no trauma and received saline instead of thymoquinone. Groups 1 and 2 were exposed to acoustic trauma using 105 dB SPL white noise for 4 hours.Results:There was a significant decrease in distortion product otoacoustic emission values and an increase in auditory brainstem response thresholds in group 1 on days 1, 5 and 10, compared with baseline measurements. In group 2, a decrease in distortion product otoacoustic emission values and an increase in auditory brainstem response threshold were observed on day 1 after acoustic trauma, but measurements were comparable to baseline values on days 5 and 10. In group 3, thymoquinone had no detrimental effects on hearing. Similarly, the control group showed stable results.Conclusion:Thymoquinone was demonstrated to be a reparative rather than preventive treatment that could be used to relieve acoustic trauma.

Distortion product otoacoustic emissions following stapedectomy versus stapedotomy

2009 ◽  
Vol 124 (1) ◽  
pp. 16-18
Author(s):  
L Migirov ◽  
M Wolf
Keyword(s):  
Otoacoustic Emissions ◽  
Surgical Techniques ◽  
Otoacoustic Emission ◽  
Normal Hearing ◽  
Stapes Surgery ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Distortion Product Otoacoustic Emission ◽  
Distortion Product ◽  
Gap Closure

AbstractObjectives:To evaluate distortion product otoacoustic emissions following stapes surgery in patients with otosclerosis, and to compare in this respect two surgical techniques used in our department.Method:This retrospective study included 17 stapedectomy and 23 stapedotomy patients aged 16–68 years who had been followed up for at least 12 months. Distortion product otoacoustic emission results at 2, 3, 4 and 5 kHz (i.e. =f2, with 2f1 − f2 = 0.6f2) were obtained pre-operatively and four weeks post-operatively. The control group included 13 volunteers aged 18–50 years with normal hearing and normal otoscopic findings.Results:Distortion product otoacoustic emissions were detected pre-operatively in 34.8 per cent of stapedotomy patients and 29.4 per cent of stapedectomy patients, and post-operatively in 91.3 per cent of stapedotomy patients and 88.2 per cent of stapedectomy patients. The differences between the stapedotomy and stapedectomy groups were statistically insignificant for each tested frequency, both pre- and post-operatively. The patients' post-operative distortion product otoacoustic emission amplitudes were less than those of normal hearing individuals, even in patients with complete air–bone gap closure and a significant improvement in hearing.Conclusion:Distortion product otoacoustic emissions were detected in most of our patients following successful stapes surgery, and appeared to be unaffected by the surgical technique or prosthesis used.

scholarly journals The Immediate and Long-Term Impact of Military Aircraft Noise on Hearing: A Cross-Sectional Comparison of Fighter Pilots and Ground Staff

2021 ◽  
Vol 18 (6) ◽  
pp. 2982
Author(s):  
Chao-Yin Kuo ◽  
Chia-Lien Hung ◽  
Hsin-Chien Chen ◽  
Cheng-Ping Shih ◽  
Rou-Huei Lu ◽  
...  
Keyword(s):  
High Frequency ◽  
Noise Exposure ◽  
Pure Tone Audiometry ◽  
Aircraft Noise ◽  
Distortion Product Otoacoustic Emission ◽  
Military Aircraft ◽  
Cross Sectional ◽  
Distortion Product ◽  
Hearing Thresholds

We examined the immediate and long-term impacts of military aircraft noise exposure on noise-induced hearing loss (NIHL) in fighter pilots and ground staff. We recruited 40 pilots, 40 ground staff, and 136 age-matched controls; all participants underwent hearing tests, including conventional pure-tone audiometry (PTA) (0.25–8.0 kHz), extended high-frequency (EHF) audiometry (9.0–18.0 kHz), and distortion-product otoacoustic emission (DPOAE) as a recent reference. A subsequent hearing test immediately after flight-mission noise exposure was requested. The results revealed higher recent hearing thresholds in pilots and ground staff than in controls. Threshold shifts at many octave band frequencies were also significantly elevated in ground staff. The grouped frequency threshold was significantly elevated in the 4–8 kHz high-frequency range. After a single flight-mission noise exposure, both ground staff and pilots showed decreased signal-to-noise ratios for DPOAE (1–8 kHz), whereas only ground staff showed significantly elevated left-ear hearing thresholds at 3, 11.2, and 12.5 kHz by conventional and EHF PTA. Fighter pilots and ground staff serve in hazardous noise-exposed environments that cause hearing damage and subsequent NIHL, but ground staff may be more vulnerable. A comprehensive hearing conservation program should be implemented to protect high-risk service members, and especially ground staff, from high-intensity noise exposure.

Vestibular evaluation in children with otitis media with effusion

2015 ◽  
Vol 129 (4) ◽  
pp. 326-336 ◽  
Author(s):  
E A Kolkaila ◽  
A A Emara ◽  
T A Gabr
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Vestibular Function ◽  
Vestibular Evoked Myogenic Potentials ◽  
Control Group ◽  
Dizziness Handicap Inventory ◽  
Vestibular Evoked Myogenic Potential ◽  
Bedside Test ◽  
Bedside Tests ◽  
Serous Otitis Media

AbstractBackground:Fifty per cent of children with serous otitis media may have some balance disturbances.Objective:To evaluate vestibular function in children with otitis media with effusion.Methods:The control group comprised 25 children with bilateral normal hearing and middle-ear function. The study group consisted of 30 children with bilateral otitis media with effusion; these were divided into 2 subgroups according to air–bone gap size. Measures included the Arabic Dizziness Handicap Inventory, an imbalance evaluation sheet for children, vestibular bedside tests for children, and air- and bone-conducted vestibular-evoked myogenic potential testing.Results:Arabic Dizziness Handicap Inventory scores and some vestibular bedside test results were significantly abnormal, with normal video-nystagmography results, in children with otitis media with effusion. Air-conducted vestibular-evoked myogenic potentials were recorded in 73 per cent of children with otitis media with effusion, with significantly delayed latencies. Bone-conducted vestibular-evoked myogenic potentials were successfully detected in 100 per cent of children with otitis media with effusion with similar results to the control group.Conclusion:The Arabic Dizziness Handicap Inventory and vestibular bedside tests are valuable tools for detecting vestibular impairment in children. Bone-conducted vestibular-evoked myogenic potentials are useful for vestibular system evaluation.

scholarly journals Hypersensitivity of Vestibular System to Sound and Pseudoconductive Hearing Loss in Deaf Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Seyede Faranak Emami
Keyword(s):  
Vestibular System ◽  
Low Frequency ◽  
Vestibular Function ◽  
Multiple Comparisons ◽  
Vestibular Evoked Myogenic Potentials ◽  
Cross Sectional ◽  
Low Frequencies ◽  
Anova Test ◽  
Hearing Thresholds ◽  
One Way Anova

The objective of this cross-sectional study is to compare bone-conducted low-frequency hearing thresholds (BClf) to cervical vestibular evoked myogenic potentials (cVEMPs) findings in prelingual adult deaf patients. The fifty participants (100 ears) included twenty healthy controls and thirty other subjects selected from patients who presented with bilateral prelingual deafness to Department of Audiology of Hamadan University of Medical Sciences and Health Services (Hamadan, Iran). Assessments comprised of audiological evaluations, cVEMPs, and computerized tomography scans. Twenty deaf patients (forty affected ears) with bilateral decreased vestibular excitability as detected by abnormal cVEMPs revealed that BClf hearing thresholds were completely absent. Ten deaf patients (twenty unaffected ears) with normal cVEMPs reported a sensation of the sound at BClf hearing thresholds (the mean for 250 Hz=41 dBHL and for 500 Hz=57.75 dBHL). Multiple comparisons of mean p 13 latencies, mean n23 latencies and peak-to-peak amplitudes between three groups were significant (P = 0.01 for all, one-way ANOVA test). Multiple Comparisons of mean BClf between three groups were significant (P = 0.00, One-way ANOVA test). Conclusion. Hypersensitivity of vestibular system to sound augments BClf hearing thresholds in deaf patients. The sensation of the sound at low frequencies may be present in patients with total deafness and normal vestibular function (predominantly saccule). This improvement disappears when saccular function is lost.

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