Cerebral Venous Thrombosis and Persistent Pulsatile Tinnitus After Sigmoid Sinus Resurfacing Surgery

2021 ◽  
pp. 014556132110382
Author(s):  
Jimin Yun ◽  
Taek Yoon Cheong ◽  
Keun-Woo Jung ◽  
Jeon Mi Lee
Keyword(s):  
Weight Loss ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Associated Factors ◽  
Rare Complication ◽  
Sigmoid Sinus ◽  
Pulsatile Tinnitus ◽  
Patient Factors ◽  
Tailored Treatment ◽  
Increased Blood Flow

We report a case with rare complication of cerebral venous thrombosis, as well as an incomplete response, after sigmoid sinus resurfacing surgery for pulsatile tinnitus (PT). A 24-year-old female patient with PT originating from the sigmoid sinus underwent sigmoid sinus resurfacing surgery. The tinnitus was immediately resolved, but it recurred with headache 5 days after surgery. A cerebral venous thrombosis was identified and treated, but PT persisted, although its frequency and loudness decreased. Sigmoid sinus resurfacing surgery is a safe and effective method to treat PT, but in some patients, it can cause serious complications and/or persistent tinnitus. In our patient, factors such as changes in blood viscosity due to warfarin intake or increased blood flow due to weight loss may have influenced the persistence of the tinnitus. It is important to identify the various associated factors and the weight of each of these factors to provide more tailored treatment of PT for individual patients in the future and to reduce complications and increase the effectiveness of sigmoid sinus resurfacing surgery.

Cerebral venous thrombosis associated with tuberculous meningitis: a rare complication of a common disease

2015 ◽  
Vol 157 (10) ◽  
pp. 1679-1680 ◽  
Author(s):  
Raghvendra Ramdasi ◽  
Amit Mahore ◽  
Juhi Kawale ◽  
Smita Thorve
Keyword(s):  
Venous Thrombosis ◽  
Tuberculous Meningitis ◽  
Cerebral Venous Thrombosis ◽  
Rare Complication ◽  
Common Disease

scholarly journals Cerebral venous thrombosis and Covid 19: Literature review

2021 ◽  
Vol 11 (2) ◽  
pp. 57-68
Author(s):  
Carlos Alexandre Martins Zicarelli ◽  
Jonathan Vinicius Martins ◽  
Wesley Vieira Doni ◽  
Rafael Rodrigues Pinheiro dos Santos ◽  
Ana Carla Mondek Rampazzo ◽  
...  
Keyword(s):  
Literature Review ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Clinical Manifestations ◽  
Risk Of Death ◽  
Cranial Sinus Thrombosis ◽  
Stent Retrievers ◽  
Low Incidence

Introduction: Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) was first detected in December 2019 in the city of Wuhan, China, and has since taken on worldwide proportions. It is known that individuals with Coronavirus disease-19 (COVID-19) have systemic clinical manifestations. Among the multisystemic effects, cerebral venous thrombosis (CVT) is responsible for high mortality rates. In this sense, understanding the association between CVT and SARS-CoV-2 infection directly impacts the disease's morbidity and mortality. Methodology: Literature review in the PubMed and Embase databases, with the following search terms: “COVID-19”, “SARS-CoV-2”, “Venous thromboembolism”, “Thrombosis”, “Cerebral Venous Thrombosis”, “Intracranial Sinus Thrombosis” and “Cranial Sinus Thrombosis”. The selected articles were written in English, which addressed the various aspects of COVID-19. Results and discussion: CVT are a rare complication of COVID-19, with an incidence between 0.02 to 1% of hospitalized patients. However, it can reach about 75% of mortality in affected individuals. Pathophysiology seems to be associated with the state of hypercoagulability and the systemic inflammatory process resulting from viral infection. Thus, recent studies show a consensus on the early anticoagulation of patients affected by the virus, to reduce mortality in these cases. However, the differences between the types of anticoagulation, Low Molecular Weight Heparin (LMWH), Unfractionated Heparin (UFH), Dabigatran have not yet been well established, although there is a predilection for the use of LMWH. Also, thrombectomy is a therapeutic intervention option that should be evaluated, due to the risk of additional endothelial injury from the use of stent retrievers. Conclusion: Although it has a relatively low incidence, CVT aggravates the condition and increases the risk of death for patients with COVID-19. Because of this, early diagnosis and evaluation of therapeutic options for CVT are essential for the development of clinical management.

Cerebral venous thrombosis: a rare complication of herpes simplex encephalitis

2019 ◽  
Vol 26 (1) ◽  
pp. 114-117
Author(s):  
M. Vedani ◽  
O. Toubas ◽  
M. Hentzien ◽  
A. Brunet ◽  
L. Andreoletti ◽  
...  
Keyword(s):  
Herpes Simplex ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Herpes Simplex Encephalitis ◽  
Rare Complication

scholarly journals A rare complication of cerebral venous thrombosis during simple percutaneous coronary intervention

Medicine ◽  
2021 ◽  
Vol 100 (4) ◽  
pp. e24008
Author(s):  
Ming Yuan Lo ◽  
Ming-Shiu Chen ◽  
Hsuan-Ming Jen ◽  
Chien-Cheng Chen ◽  
Thau-Yun Shen
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Rare Complication ◽  
Coronary Intervention ◽  
Percutaneous Coronary

scholarly journals Spontaneous occult intracranial hypotension precipitating life-threatening cerebral venous thrombosis: case report

2018 ◽  
Vol 28 (6) ◽  
pp. 669-678 ◽  
Author(s):  
Avital Perry ◽  
Christopher S. Graffeo ◽  
Waleed Brinjikji ◽  
William R. Copeland ◽  
Alejandro A. Rabinstein ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Intracranial Hypotension ◽  
Primary Repair ◽  
Rare Complication ◽  
External Ventricular Drain ◽  
Spontaneous Intracranial Hypotension ◽  
Mass Effect ◽  
Complete Recovery ◽  
Csf Leak

Spontaneous intracranial hypotension (SIH) is an uncommon headache etiology, typically attributable to an unprovoked occult spinal CSF leak. Although frequently benign, serious complications may occur, including cerebral venous thrombosis (CVT). The objective of this study was to examine a highly complicated case of CVT attributable to SIH as a lens for understanding the heterogeneous literature on this rare complication, and to provide useful, evidence-based, preliminary clinical recommendations. A 43-year-old man presented with 1 week of headache, dizziness, and nausea, which precipitously evolved to hemiplegia. CT venography confirmed CVT, and therapeutic heparin was initiated. He suffered a generalized seizure due to left parietal hemorrhage, which subsequently expanded. He developed signs of mass effect and herniation, heparin was discontinued, and he was taken to the operating room for clot evacuation and external ventricular drain placement. Intraoperatively, the dura was deflated, suggesting underlying SIH. Ventral T-1 CSF leak was identified, which failed multiple epidural blood patches and required primary repair. The patient ultimately made a complete recovery. Systematic review identified 29 publications describing 36 cases of SIH-associated CVT. Among 31 patients for whom long-term neurological outcome was reported, 25 (81%) recovered completely. Underlying coagulopathy/risk factors were identified in 11 patients (31%). CVT is a rare and potentially lethal sequela occurring in 2% of SIH cases. Awareness of the condition is poor, risking morbid complications. Evaluation and treatment should be directed toward identification and treatment of occult CSF leaks. Encouragingly, good neurological outcomes can be achieved through vigilant multidisciplinary neurosurgical and neurocritical care.

Abstract TP222: Characteristic Phenotype and Prognostic Factors in Magnetic Resonance Perfusion Weighted Image of Cerebral Venous Thrombosis

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Moo-seok Park ◽  
Woo-Keun Seo ◽  
Oh Young Bang ◽  
Chin-Sang Chung ◽  
Kwang Ho Lee ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Magnetic Resonance ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Sigmoid Sinus ◽  
Weighted Image ◽  
Magnetic Resonance Perfusion ◽  
Good Outcome ◽  
Univariate Analyses

Introduction: Cerebral venous thrombosis is a rare form disease. It can be difficult to diagnose and predict patient’s outcome. There are a few reports suggesting characteristic image phenotype and hypothesis of prognosis prediction but those are very rare and still controversial. We sought to identify image phenotype and prognostic factors associated with cerebral venous thrombosis using magnetic resonance perfusion weighted image. Methods: We retrospectively collected patients who had cerebral venous thrombosis from January 2000 to December 2015. Patients who had underwent magnetic resonance image with perfusion weighted image, non-contrast computerized tomography and magnetic resonance venography were enrolled. Perfusion weighted image was analyzed by visual assessment. We evaluated patient outcome by checking presence of recanalization and disappearance of symptom. Results: We collected 35 patients who had cerebral venous thrombosis. The mean age of these patients was 42.91 ± 15.47, and 57% were women. Perfusion abnormalities were observed in 25 cases. Cerebral blood volume abnormality was observed in 31 cases, cerebral blood flow abnormality in 31 cases, mean transit time abnormality in 18 cases, and time to peak abnormality in 22 cases. All perfusion abnormalities were localized in the areas adjacent to the occluded sinuses. In the univariate analyses, our study showed location of cerebral venous thrombosis was correlated with good outcome (transverse sinus: p = 0.042, sigmoid sinus: p = 0.026). Gradient echo sequences’ vessel sign ( p = 0.094) and cerebral blood flow on perfusion weighted image ( p = 0.055) was also related with good outcome. In the multivariate model with adjustment for variables with p<0.10 in the univariate analyses, sigmoid sinus thrombosis (Odd ratio 0.125, 95% confidence interval 0.014-0.756, p = 0.034) and increased cerebral blood flow on perfusion weighted image (Odd ratio 17.749, 95% confidence interval 1.427-544.176, p = 0.044) remained an independent predictor for good outcome. Conclusions: Our study suggest that cerebral blood flow is able to predict good outcome in cerebral venous thrombosis. It is similar to penumbra phenomenon in ischemic stroke.

Suspected adverse reaction to compounded preparations prescribed for weight loss: two cases of cerebral venous thrombosis

2020 ◽  
Vol 13 (3) ◽  
pp. e233746 ◽  
Author(s):  
Beatrice Mainoli ◽  
Mariana Carvalho Dias ◽  
Patricia Canhão ◽  
Mário Miguel Rosa
Keyword(s):  
Weight Loss ◽  
Adverse Reaction ◽  
Venous Thrombosis ◽  
Adverse Drug Reactions ◽  
Oral Contraceptives ◽  
Cerebral Venous Thrombosis ◽  
Drug Reactions ◽  
Suspected Adverse Reaction ◽  
Life Threatening ◽  
Active Substances

We report two cases of cerebral venous thrombosis associated with the use of compounded preparations containing several active substances prescribed for weight loss. In both cases there is suspicion of additive/synergic interaction with oral contraceptives. The adverse drug reactions were considered serious, being life-threatening and causing hospitalisation for days.

scholarly journals Bacterial meningitis complicated by cerebral venous thrombosis

2020 ◽  
Vol 5 (4) ◽  
pp. 394-401
Author(s):  
Shahrzad S Deliran ◽  
Matthijs C Brouwer ◽  
Jonathan M Coutinho ◽  
Diederik van de Beek
Keyword(s):  
Bacterial Meningitis ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Clinical Characteristics ◽  
Clinical Course ◽  
Rare Complication ◽  
Transverse Sinus ◽  
Causative Pathogen ◽  
Neurologic Deficits ◽  
Nose And Throat

Introduction Community-acquired bacterial meningitis may be complicated by cerebral venous thrombosis (CVT), but this has not systematically been studied. Methods We evaluated clinical characteristics and outcome of CVT in adults with community-acquired bacterial meningitis in a prospective nationwide cohort study of bacterial meningitis (2006–2018) in the Netherlands. Results CVT occurred in 26 of 2220 episodes with bacterial meningitis (1%). The diagnosis of CVT was made on the day of presentation in 15 patients (58%) and during hospital stay in 11 patients after a median of 6 days (IQR 2–7). Sinusitis or otitis was present in 16 of 24 patients (67%). Patients with CVT presented more often in a coma than those without CVT (53 vs. 18%; P = 0.001) and the clinical course was more often complicated by focal neurologic deficits (58 vs. 22%; P < 0.001). Twelve patients of 26 (46%) had parenchymal lesions on neuroimaging, of whom two (8%) were specific for CVT. The transverse sinus was most frequently thrombosed (18 of 26; 69%). Streptococcus pneumoniae was the most common causative pathogen, occurring in 17 of 26 patients (65%). Eleven patients (44%) received anticoagulant therapy with heparin and none of them developed intracerebral hemorrhage during admission. Unfavorable outcome, as defined as a score on the Glasgow Outcome Scale <5, occurred in 14 of 26 patients (54%) and 4 patients (15%) died. Discussion and conclusion CVT is a rare complication of bacterial meningitis and mainly occurs in patients with coma, ear, nose and throat infections, and focal neurologic deficits.

Sign in / Sign up

Export Citation Format

Share Document