Comparative Bioavailability of d-pseudoephedrine from a Conventional d-pseudoephedrine Sulfate Tablet and from a Repeat Action Tablet
1982 ◽
Vol 10
(2)
◽
pp. 126-128
Keyword(s):
The bioavailability of a single dose of d-pseudoephedrine sulfate administered to male volunteers in repeat action tablet* form (60 mg d-pseudoephedrine sulfate in the coat and 60 mg d-pseudoephedrine sulfate in the core) was compared with the bioavailability of an equivalent quantity of the drug given as two 60 mg conventional tablets, one given at 0 hour and the second 6 hours later. There was no significant difference (p > 0·10) between the conventional tablets and the repeat action tablet formulation in area under the plasma concentration-time curve and the maximum plasma concentration of d-pseudoephedrine. Based on the data, we conclude that the repeat action tablet formulation and the conventional tablet are bioequivalent.
1982 ◽
Vol 10
(2)
◽
pp. 122-125
1982 ◽
Vol 10
(4)
◽
pp. 274-277
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1996 ◽
Vol 30
(11)
◽
pp. 1223-1226
◽
Keyword(s):
2015 ◽
Vol 60
(1)
◽
pp. 105-114
◽
Keyword(s):
2010 ◽
Vol 54
(1)
◽
pp. 411-417
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1988 ◽
Vol 16
(1)
◽
pp. 50-60
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