Primary Anorectal Malignant Melanoma: Report of two Cases

2000 ◽  
Vol 86 (4) ◽  
pp. 356-358 ◽  
Author(s):  
Bruno Ceccopieri ◽  
Anna Rosa Marcomin ◽  
Feliciano Vitagliano ◽  
Paolo Fragapane

Primary anorectal malignant melanoma is a fairly uncommon but highly malignant disease. It is sometimes mistaken for benign conditions such as hemorrhoids or rectal polyps. Here we describe two cases of primary malignant melanoma of the rectum: in one patient a wide local excision (WLE) was performed and in the other an abdominoperineal resection (APR), both with curative intent. Both patients developed systemic recurrences and died of their disease at 24 and 10 months, respectively. In conclusion, the prognosis of anorectal melanoma is poor, irrespective of surgical treatment. WLE is the first choice for primary anorectal melanoma, while APR should be reserved for those cases where complete transrectal tumor resection is technically impossible.

2020 ◽  
Vol 7 (07) ◽  
pp. 4871-4874
Author(s):  
Amal Hajri ◽  
Abdessamad El Azhary ◽  
Driss Erguibi ◽  
Rachid Boufettal ◽  
Saad Rifki El Jai ◽  
...  

Primary anorectal malignant melanoma is an extremely rare condition. It appears at the third highest frequency after melanomas of the skin and retina. Its prognosis is dreadful because of the early onset of metastases. The treatment remains essentially surgical. We report an observation of primitive anorectal melanoma, collected at the department of surgery for digestive cancers and liver transplantation of the Ibn Rochd University Hospital of Casablanca, with a review of the literature. In order to analyse the clinical, paraclinical and therapeutic characteristics of primary anorectal melanoma.


2021 ◽  
Vol 5 (2) ◽  
pp. 192-196
Author(s):  
Tomoyuki Nagaoka ◽  
Toshiya Nagasaki ◽  
Takashi Akiyoshi ◽  
Toshiki Mukai ◽  
Tomohiro Yamaguchi ◽  
...  

2018 ◽  
Vol 9 (4) ◽  
pp. 519-523 ◽  
Author(s):  
Syed Nusrath ◽  
Subramanyeshwar Rao Thammineedi ◽  
Sujit Chyau Patnaik ◽  
K. V. V. N. Raju ◽  
Satish Pawar ◽  
...  

2008 ◽  
Vol 23 (12) ◽  
pp. 1257-1262 ◽  
Author(s):  
Satoshi Ishizone ◽  
Naohiko Koide ◽  
Fumitoshi Karasawa ◽  
Noriyuki Akita ◽  
Futoshi Muranaka ◽  
...  

1986 ◽  
Vol 73 (1) ◽  
pp. 68-69 ◽  
Author(s):  
M. W. N. Ward ◽  
G. Romano ◽  
R. J. Nicholls

1987 ◽  
Vol 79 (4) ◽  
pp. 681
Author(s):  
Richard W. Griffiths ◽  
M. W. N. Ward ◽  
G. Ramano ◽  
R. J. Nicholls

2018 ◽  
Vol 69 (7) ◽  
pp. 1915-1917
Author(s):  
Bogdan Mihai Marinescu ◽  
Cristian Dragos Stefanescu ◽  
Ioana Tuhar ◽  
Dragos Muraru ◽  
Ionut Guzganu ◽  
...  

There is no perfect method of nasal reconstruction. All reconstruction types have advantages and disadvantages equally. Perhaps, the personalized medicine can be best illustrated by this surgical pathology. The present paper describes our experience with locoregional fasciocutaneous flaps together with cartilage grafts as surgical treatment for patients with nasofacial cutaneous tumors. After describing the general conditions for the 12 patients included in the study we presented the surgical management of an old woman with a nasal tumor (basal cell carcinoma) of 50/40/35 mm. Favorable results (from aesthetic and functional point of view) were obtained for most patients included in the study. There was only one recurrence, at 1 year postoperatively to the patient diagnosed with malignant melanoma. Considering the etiopathogenetic mechanisms of nasofacial cutaneous tumors and the other nasal reconstruction procedures, more extensive and multicenter studies are needed.


2008 ◽  
Vol 108 (4) ◽  
pp. 692-697 ◽  
Author(s):  
Thomas M. Kinfe ◽  
Hans-Holger Capelle ◽  
Joachim K. Krauss

Object The object of this study was to investigate the impact of surgical treatment on tremor caused by posterior fossa tumors. Methods The authors performed a retrospective evaluation of 6 cases involving patients with tremors due to posterior fossa tumors. Patients who had been treated with neuroleptic medication or had a family history of movement disorders were excluded. All patients had postural or kinetic tremors. Tremor was mainly unilateral. The study group included 5 women and 1 man. Mean age at surgery was 59 years. Five patients underwent total or subtotal tumor resection, and 1 patient underwent stereotactic biopsy only. The histological diagnosis was epidermoid tumor in 2 patients, metastasis in 2 others, and vestibular schwannoma and low-grade glioma in 1 each. Results Two patients had no improvement of tremor, postoperatively. In both of these patients the tumor (low-grade glioma in 1, metastasis in the other) involved the dentate nucleus directly. In the other patients, a compressive effect on the dentate nucleus or the dentatothalamic pathways was present without invasion of the cerebellar structures, and immediate or gradual amelioration of the tremor was observed postoperatively. Conclusions The prognosis of tremor due to posterior fossa tumors appears to depend mainly on the involvement of tremor-generating structures. The prognosis appears to be favorable in those patients with compression of these substrates, whereas primary invasion by tumor has a poor prognosis. Caution must be used in generalizing the findings of this study because of the small number of cases in the series.


1999 ◽  
Vol 56 (6) ◽  
pp. 318-323
Author(s):  
Bösch ◽  
Banic

Die frühe Erkennung und vollständige Exzision ist entscheidend für den Krankheitsverlauf des malignen Melanoms der Haut. Der Sicherheitsabstand bei der chirurgischen Resektion ist heute geringer als vor Jahren und liegt abhängig von der Tumordicke zwischen 1 und 3 cm. Die elektive Lymphadenektomie, das heißt die prophylaktische Entfernung der regionalen Lymphknoten gleichzeitig mit der Nachexzision des Primärtumors, ist umstritten. Sie ist mit einer hohen Komplikationsrate behaftet und bringt nur für eine kleine Subgruppe eine Verbesserung der Überlebensrate. Ein neues Konzept, die Sentinellymphknotenexzision, gewinnt zunehmend an Bedeutung. Durch bestimmte Markierungsmethoden wird derjenige Lymphknoten ermittelt, welcher primär den Lymphabfluß aus dem vom Melanom betroffenen Hautbereich erhält. Dieser Lymphknoten ist repräsentativ für den Metastasenstatus seiner Station. Falls er bei der histologischen Untersuchung eine Metastase zeigt, wird eine vollständige Exzision der regionalen Lymphknotenstation vorgenommen. Diese Methode vermag weitere Hinweise auf die Biologie des Melanoms zu geben und dient als Grundlage für die Wahl von adjuvanten Therapien. Ob sie zu einer Verlängerung der Überlebenszeit führt, ist Gegenstand einer laufenden multizentrischen Studie. Systemische Melanommetastasen haben eine schlechte Prognose. Die chirurgische Resektion von solitären Fernmetastasen hat ihre Bedeutung in der palliativen Behandlung des Melanoms, in Kombination mit adjuvanten Therapien.


ORL ro ◽  
2016 ◽  
Vol 3 (1) ◽  
pp. 44-49
Author(s):  
Bogdan Mocanu ◽  
Daniel Mirea ◽  
Silviu Oprescu ◽  
Anca Vișan ◽  
Mihai Tușaliu ◽  
...  

Introduction. The primitive malignant melanoma of nasal mucosa and paranasal sinus is a rare tumor of uncertain etiology, with unpredictable biologic behavior and bad prognosis. Unlike skin melanomas, there are no risk factors and the disease is frequently manifested in older patients, whose clinical otorhinolaryngology complaints are normally non-specific and ranges from nasal obstruction to rhinorrhea and epistaxis. Unfortunately, this disease is diagnosed basically in advanced stages which makes the surgery difficult. Objective. To report a case of primitive malignant melanoma of nasal mucosa, ethmoid and frontal sinuses, that was diagnosed in 2015. It was performed a subtotal resection in another hospital in 24.08.2015, with a large local reccurence. Report. Our patient was a 78-year-old woman with bilateral nasal obstruction, light epistaxis and unilateral rhinorrhea. The ENT, CT and  MRI exams showed a tumour with important, invasion of the nasal cavity structures (billateral nasal bones, left frontal process of the maxilla, the superior midpoint of the nasal septum, bilateral middle and superior turbinates, left ethmoid and bilateral frontal sinuses). The patient was submited for surgery: total macroscopic resection in the combined endoscopic approach; transnasal and modified lateral rhinotomy with titaniul plates reconstruction of the external nose architecture. Conclusions. Malignant melanomas of nasal mucosa are, in general, diagnosed in advanced stages. Their histological characteristics in the mucosa makes difficult the surgical treatment, which is one of the most efficient options, because they are resistant to chemo and radiotherapy. The early diagnosis and a good surgical treatment plan are the best option for this tumor nowadays.  


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