Pituitary Chromophobe Adenoma in a Cat

1973 ◽  
Vol 10 (3) ◽  
pp. 232-237 ◽  
Author(s):  
F. A. Zaki ◽  
S.-K. Liu

Chromophobe adenoma was diagnosed in the pituitary gland of an 11-year-old domestic shorthaired cat. Histologically, the tumor consisted of a mass of cells with scant sinusoidal arrangement and connective tissue stroma and few blood vessels. In areas the neoplastic cells contained large vacuoles that occupied the entire cytoplasm and pushed the nuclei aside.

Author(s):  
C. C. Capen ◽  
S. L. Martin

A syndrome of feminization associated with testicular neoplasms has been reported frequently in male dogs but occurs rarely in man and other species. Although an excessive secretion of estrogenic hormones has been suspected on the basis of clinical and pathologic findings, elevated circulating levels have not been demonstrated conclusively. The specific objective of this investigation was to evaluate ultrastructural1y functional Sertoli cell neoplasms from 5 male dogs with feminization and to correlate these findings with the results of estrogen assays.The affected testes were enlarged, irregularly lobulated, firm and were retained in the abdomen of all dogs (Fig. 1A). The neoplastic cells were spindle-shaped or polyhedral and formed distinct tubules separated by a delicate connective tissue stroma (Fig. 1B).


2017 ◽  
Vol 19 (77) ◽  
pp. 117-120
Author(s):  
Zh.H. Stegney

Tissue components, intraorganic blood vessels and indicators of correlation between the area of these structures in the thymus of 1, 5, 10 and 20 day-old calves were investigated. Newborns calves at birth had different morphofunctional status. Thymic blood vessels are represented as interlobular and intralobular blood vessels as confirmed by other authors. In the cortical portion blood vessels were branching radially, in the medullary portion they formed a polygonal plexus. In 1-day-old calves of average morphofunctional status the area of organ’s parenchyma was less and the area of connective tissue stroma was bigger than in the calves of high status. This indicates the delay of thymus formation as an organ and suppression of its functional activity in calves of average morphofunctional status. In this case, the area of thymic blood vessels of 1-day-old calves of high morphofunctional status was bigger than of average morphofunctional status calves. The area of thymic parenchyma in calves up to 5-days old was increasing, and the area of connective tissue stroma was reducing. Characteristically, the area of parenchyma and stroma in the calves of this age reached the values that calves of high morphofunctional status had. In older calves the area of parenchyma was slightly decreasing and the area of stroma was increasing. Our studies showed that the correlative relationships between the area of blood vessels and tissue components of thoracic part of thymus of calves with different morphofunctional status were variable in the firmness and character. In thoracic part of thymus of 1-day-old calves with high morphofunctional status of the body the correlative relationships between the area of blood vessels and tissue components were tight and reversible. Their firmness was slightly less in calves of medium status. With increasing of calves’ age the correlative relationships changed asynchronously in firmness and character: in 5- and 10-days-old calves they were tight, weak and reversible, and in 20-days-old calves they were tight, positive and reversible.


1974 ◽  
Vol 11 (2) ◽  
pp. 138-143 ◽  
Author(s):  
F. A. Zaki ◽  
S.-K. Liu

Adenocarcinomas of the olfactory glands were diagnosed in five dogs. The tumors had invaded the adjacent olfactory and prefrontal areas of the cerebral hemispheres. The masses consisted of large sheets of neoplastic epithelial cells separated by connective tissue stroma. In some areas there were hemorrhage and necrosis. The anterior parts of the cerebral hemispheres had been destroyed by the invasive neoplastic cells, and the white matter in the areas was very edematous. Review of the medical and veterinary literature yielded no description of tumors originating in the olfactory glands.


Author(s):  
S.M. Shakirova ◽  
◽  
D.M. Shakirova ◽  
◽  

As a result of the study, it was found that poisoning of rats with the herbicide 2,4 - DA for 4 weeks causes a decrease in the number of neurocytes in the celiac plexus, changes the protein synthesizing and energy systems of the cell, and accumulates residual structures in the form of lipofuscin. In the neuroplasm, the number of neurofilaments and neurotubules decreases, the organization of the myelin layer of fibers is disrupted. Changes affect the structure of the intima and media of blood vessels, leading to a violation of their transport function. When rats are treated with Taktivin, they show positive dynamics in the structure of the celiac plexus; the protein-synthesizing system is restored in the nuclei and neuroplasm of a number of cells. In the connective tissue stroma, the ultrastructure of collagen fibers improves, and the number of blood vessels increases.


Author(s):  
E. J. Kollar

The differentiation and maintenance of many specialized epithelial structures are dependent on the underlying connective tissue stroma and on an intact basal lamina. These requirements are especially stringent in the development and maintenance of the skin and oral mucosa. The keratinization patterns of thin or thick cornified layers as well as the appearance of specialized functional derivatives such as hair and teeth can be correlated with the specific source of stroma which supports these differentiated expressions.


2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Ramalingam Suganya ◽  
Narasimhan Malathi ◽  
Subramani Vijaya Nirmala ◽  
Chinnaswami Ravindran ◽  
Harikrishnan Thamizhchelvan

Choristomas are rare entities which are aggregates of microscopically normal cells or tissues in aberrant locations. They are a “heterotopic” rest of cells, as they appear as a tumor-like mass. Herein we report a case of cartilaginous choristoma in a 54-year-old male who presented with a swelling on right lower gingiva. The histopathological examination revealed features of a well circumscribed mass of mature cartilage in a dense fibrous connective tissue stroma.


1972 ◽  
Vol 22 (3) ◽  
pp. 200-207 ◽  
Author(s):  
Asao Hirano ◽  
Uwamie Tomiyasu ◽  
H. M. Zimmerman

1971 ◽  
Vol 34 (6) ◽  
pp. 726-729 ◽  
Author(s):  
Bronson S. Ray ◽  
Russell H. Patterson

✓ Between 1950 and 1969, 165 operations were performed on 146 patients for the treatment of chromophobe adenoma of the pituitary gland unassociated with either acromegaly or Cushing's syndrome. The over-all operative mortality was 1.2%, and no deaths occurred in 138 cases operated on for the first time. In 106 of the patients who had not received prior treatment, vision was improved in 80% of cases and returned to normal in 50%. In the group of patients whose initial treatment was surgery, postoperative radiation therapy was administered in one-half of the cases. The rate of recurrence was 8% in those who received radiation and 22% in those who did not. Recurrence of symptoms within less than 1 year often was due to a hemorrhagic cyst which could be treated better by reoperation than by radiation therapy.


In Vivo ◽  
2021 ◽  
Vol 35 (1) ◽  
pp. 313-317
Author(s):  
SATOSHI YOKOSE ◽  
YUKA KATO ◽  
KATSUTOSHI MATSUMOTO ◽  
PERRY R. KLOKKEVOLD ◽  
HENRY H. TAKEI ◽  
...  

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