scholarly journals Mucosal Microhernias in the Nonhuman Primate Colon: Their Role in the Pathogenesis of Colonic Disease

1982 ◽  
Vol 19 (7_suppl) ◽  
pp. 134-140 ◽  
Author(s):  
G. B. D. Scott

Microhernias of colonic mucosal glands through the muscularis mucosae are common in human and nonhuman primate colons, and are related to submucosal lymphoid nodules. In nonhuman primates they have been shown to play an important role in the spread of inflammatory diseases from the lamina propria to the submucosa by allowing the infective agents to pass through the muscularis mucosae. The lymphoid tissue of the alimentary tract is composed predominantly of B lymphocytes and produces humoral antibodies. This property of the lymphoid component of these microhernias may thus play a significant role in determining which infective colonic diseases penetrate into the submucosa and which remain largely confined to the lamina propria.

2020 ◽  
Vol 1 (1) ◽  
pp. 53-56
Author(s):  
Indu V.R. ◽  
Biju S. ◽  
Lucy K. M. ◽  
Maya S.

Histomorphological study was conducted on the oesophageal tonsils in six broiler Vigova Super-M ducks of six to eight weeks age. The location of the tonsil was at the junction between oesophagus and proventriculus. In histological sections six to eight isolated tonsillar units were seen in the lamina propria near the base of the oesophageal folds. Each tonsillar unit consisted of a crypt lined by lymphoepithelium and surrounded by dense lymphoid tissue. The tonsillar units were seen encapsulated by connective tissue and composed of many large lymphoid nodules separated by internodular areas. The secretory portion of the mucosal glands of the oesophagus were firmly associated with the lymphoid tissue and the cylindrical epithelium was transformed to lymphoepithelium. The oesophageal tonsils offered immunological protection at the entrance of stomach. Keywords: Oesophageal tonsils, Histomorphology, Ducks


1934 ◽  
Vol s2-77 (306) ◽  
pp. 243-253
Author(s):  
K. MANSOUR

1. Rhizopertha dominica, F., Sinoxylon ceratoniae, L., and Bostrychoplites Zickeli, Mars., possess paired mycetomes full of bacteria-like micro-organisms. 2. The transmission of the micro-organisms from one generation of the host to the next is carried out in the following way: (a) Micro-organisms from the mycetomes invade the testis lobes, multiply, and mix with the sperms. (b) These micro-organisms pass with the sperms during copulation into the bursa copulatrix of the female. (c) From this region they pass through the micropyle of the fully formed eggs during their passage to the outside, and thus the infection is accomplished. 3. The invasion of the testis lobes by micro-organisms causes abnormality in the process of spermatogenesis. 4. The micro-organisms in the developing egg are first seen near the micropylar region in the peripheral protoplasm. In a later stage these micro-organisms, which have multiplied greatly by then, are to be found in between the yolk globules towards the posterior pole of the egg. From this stage onwards the course these micro-organisms follow till they reach their final destination in the larva has not been followed. 5. The mycetomes throughout life remain quite isolated from the alimentary tract. 6. The biological relation between the micro-organisms and their host is also discussed.


2016 ◽  
Vol 18 (2(66)) ◽  
pp. 166-176
Author(s):  
Y.G. Storchak ◽  
Y.V. Kisera

There are results of the histological research of the immune system organs of rabbits after injection with a prophylactic drug «Pneumo-Pro», which includes two components: Streptococcus pneumoniae and 4% ethanol-water extract of propolis. Tentative reseaches on the development of preventive drug «Pneumo-Pro» showed enhancement of post-vaccination immunity in the application on the basis of propolis preparations. Histological reseaches of the diverticulum of the ileum and appendix found a significant amount of lymphoblasts, frequently visualized mitosis of lymphocytes in the center of submucosal lymphoid nodules is. Large, medium and small lymphocytes, macrophages are located in the dome of submucosal lymphoid nodules. The crown of the lymphoid nodules contains mainly lymphocytes of different maturity. Necrotic cells are rare. There is increase the amount of volume crowded lymphoid nodules in the lamina propria and submucosa in compare with the control group. Most of lymphoid nodules are located under the crypts, only a few of them are in contact with the intestinal lumen. Histological reseaches of the appendix of the experimental group of animals injected with «Pneumo-Pro» found B-lymphocytes, macrophages and interdigitive cells  are located in the periphery of the lymphoblasts. Quite often mitosis of lymphoid cells are visualized. Some lymphocytes are exposed with necrotic changes, resulting in small intervals are present between lymphoid elements. The peripheral part of the lymphoid nodules and interfollicular zone contain a significant number of T-lymphocytes. Crypts are placed above the top of many follicles. In the lamina propria and submucosa of the appendix there are numerous, voluminous accumulations of lymphoid tissue, which form the clusters of submucosal lymphoid nodules. The reseaches indicate an increase in the functional activity of nonspecific factors of resistance and immunobiological reactivity of organism of animals after injection with a prophylactic drug «Pneumo-Pro».


2012 ◽  
Vol 50 (4) ◽  
pp. 393-401
Author(s):  
L. De Coster ◽  
P. Eloy ◽  
L. Ferdinande ◽  
J. Taildeman ◽  
C.A. Cuvelier ◽  
...  

Background: Composition changes of extracellular matrix (ECM) can lead to functional disorders of the upper airways (UA). The aim of this study was to systematically measure both the association patterns and the correlation degree between tissue composition parameters in UA inflammatory diseases. Methodology: Nasal samples were obtained from patients with chronic rhinosinusitis with (CRS+NP), without nasal polyps (CRS), with post-operative adhesions (S) and normal nasal mucosa (NM). A reproducible semi-quantitative method, which takes epithelial and lamina propria damages into account was applied for haematoxylin and eosin, alpha-smooth muscle actin, reticulin, elastin, laminin and collagen type IV stainings. Results: The most severe cases of epithelial shedding have been found in a significant higher amount in CRS+NP when compared with NM. The most severe cases of inflammatory reaction were mainly found in CRS+NP. CRS+NP had significantly more severe cases of oedema than NM. Excluding elastin, networks in other ECM proteins were found modified in fibrotic fields but to a lesser extend in oedematous regions in all conditions. Conclusion: Although non specific, oedema in the lamina propria is a key-feature of CRS+NP, while fibrosis, massively present in CRS and S, affects profoundly the distribution of ECM proteins in these areas.


2019 ◽  
Vol 13 (2) ◽  
Author(s):  
Aliman Irfandi ◽  
Cut Dahlia Iskandar ◽  
Zainuddin Zainuddin ◽  
Dian Masyitha ◽  
Fitriani Fitriani ◽  
...  

Domestical catfish is grouped into omnivora, although the fish is tended into carnivora.  The aim of the present study was to investigate histology of alimentary tract of domestical catfish (Clarias batrachus). In order to determine alimentary tract of domestical catfish, oesophagus, gastric and intestines is investigated by Haematoxilin Eosin. Histology exploration was performed each layer of alimentary tract’s wall consist of lamina epithelia, propria, and muscularis mucosa. Collagen connective tissue was developed tunica submucosa. The muscle of tunica muscularis was performed circular and elongated. Dense connective tissue and blood vessels was located in the tunica serosa. Histology exploration revealed has stratified squamous epithelium, mucosit cells, eosinophilic club cells on the lamina epithelia, and taste buds on the lamina propria in oesophagus. Gastric was establised simple prismatic cells, and glands of gastric on the lamina propria. Furthermore intestine was showed villi and goblet cells. There were not showed Brunner and Liberkhun gland. In conclusion, histology of alimentary tract was revealed from tunica mucosa, submucosa, and serosa.


Author(s):  
Manisha Paneru ◽  
Ajit Nepal ◽  
Binam Ghimire

Foreign Body (FB) ingestion is common condition in pediatric population .Curious nature and tendency to put objects in mouth are the key factors for its higher prevalence among them. Most of the ingested FB pass through the entire alimentary tract uneventful, however some require surgical interventions for its removal.


2020 ◽  
Author(s):  
Varsha Gupta ◽  
Muneer Mohhamad Farooqui ◽  
Ajay Prakash Sharma ◽  
Archana Pathak

AbstractThe study was conducted on 36 developing reticulum from healthy and normal embryos/ foeti of Indian goat. Embryos/foeti were assigned into three groups. Histo-differentiation of reticulum of goat stomach took place at 38 days of gestation. The wall of foetal reticulum was made up of three strata i. e. epithelium, pleuripotent blastemic tissue and serosa up to 49 days of fetal age and definite four layers viz. epithelium, propria-submucosa, tunica muscularis and serosa were observed first at 51 days of gestation. Upto 100 days of gestation the reticulum was lined by undifferentiated stratified epithelium and thereafter gradually transformed into stratified squamous epithelium. Keratinization was noticed at term. Primary and secondary reticular crests made their appearance at 60 and 112 days of gestation, respectively. Corial papillae were detected in primary and secondary reticular crests at 121 and 145 days of gestation, respectively. Near term, the core of the reticular crest also contained muscularis mucosae in its proximal 1/3rd region while core of the corial papillae contained only lamina propria. Reticular, collagen and elastic fibers came into sight at 46, 100 and 134 days of gestation, respectively.Summary statementThe study was conducted on intrauterine reticulum of Indian goat. From this study it can be concluded that the histogenesis of reticulum was almost completed in prenatal life. However, to become functional it still required more time as the relative sizes of reticulum and process of keratinization were yet to be completed.


2018 ◽  
Vol 20 (83) ◽  
pp. 200-203
Author(s):  
N. Dyshlyuk

The morphology of the esophageal mucosa in long-eared owl (Asio otus) and Eurasian jay (Garrulus glandarius) has been studied. Samples with exception of the region of the esophageal tonsil were obtained from 3 adult birds of each species. They were studied by light microscopy using classical methods of morphological research. The tissue samples were fixed in 10% neutral buffered formalin and embedded in paraffin block and finally the section were cut at 5–10 µm thickness using sliding microtome and stained with hematoxylin and eosin, according to Van Gizon and Weigert and impregnated with silver nitrate according to Kelemen. The esophageal mucosa consisted of four layers: epithelium, lamina propria, muscularis mucosae, and submucosa. The epithelium was stratified squamous and better developed in the cranial part of the esophagus. The lamina propria was represented by a loose connective tissue with small amount of elastic fibers. In the long-eared owl tightly located numerous small secretory sections of the esophagus glands organised in 1–3, and in branches of large folds up to 6 layers, were found. Their short excretory ducts opened to the surface of the mucosa. The muscularis mucosae was represented by a smooth muscle tissue with bundles of cells directed longitudinally and in some areas appeared to be absent. The submucosa was well developed, and as well as lamina propria was formed by a loose connective tissue with a large number of elastic fibers. In the submucosa of the Eurasian jay secretory departments of large, not tightly located, esophageal mucous glands were found. The esophageal mucosa of this birds formed well-developed folds, which were composed of  all its layers. Their number in the long-eared owl was 20–25 and in the Eurasian jay – 5–9. The shape of folds on the transverse section is not the same: in the long-eared owl it was finger-shaped and leaf-shaped, but in the Eurasian jay it was wedge-shaped. Some large folds in the long-eared owl branched into the secondary mucosal folds. The height of folds in cranial part of the esophagus was larger than in caudal part. In both parts of the esophagus of long-eared owl  the height of the large and middle folds was larger than that in the Eurasian jay. The height of small folds in the Eurasian jay was greater than that in the long-eared owl. In both parts of the esophagus of this birds, the fold’s width at the base exceeded its width at the top. In the Eurasian jay the width of base and top of large, medium and small folds was larger than that in the long-eared owl. The esophageal mucosa was poor on immune formations. They were represented by single accumulations of diffuse lymphoid tissue, and in the Eurasian jay – even by secondary lymphoid nodules.


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