scholarly journals Muscle Strength following Anaesthesia with Atracurium and Pancuronium

1988 ◽  
Vol 16 (3) ◽  
pp. 255-259 ◽  
Author(s):  
M. O'Connor ◽  
W. J. Russell
Keyword(s):  
Grip Strength ◽  
Muscle Weakness ◽  
Muscle Power ◽  
Handgrip Strength ◽  
Recovery Phase ◽  
Postoperative Recovery ◽  
Time Interval ◽  
General Anaesthetic ◽  
Elimination Kinetics ◽  
Significant Difference

Postoperative recovery from muscle weakness was investigated by handgrip strength after general anaesthesia using short- and long-acting muscle relaxants. Handgrip strength was measured on four occasions, preoperatively, before and after premedication, and postoperatively, both as soon as the patient could sustain a five-second headlift and one hour later. Twenty patients received either atracurium 0.6 mg/kg or pancuronium 0.1 mg/kg as part of a general anaesthetic technique with neostigmine reversal. Compared with their initial preoperative hand strengths, the two relaxant groups showed only an insignificant decrease in grip strength to 92% after premedication. Postoperatively when a five-second headlift was achieved, the patients in both groups were weak. The group given atracurium had a mean of 60% of their initial grip strength and those given pancuronium had a mean of 44%. This difference in strength was statistically significant from the initial level and from each other. However, there was no difference between the groups in the time interval from administering reversal to achieving a sustained headlift. One hour later in both groups grip strength was much better, within 80% of that seen after premedication in most patients, and no significant difference in grip strength was seen between the groups. This study demonstrates that patients who receive relaxant anaesthesia have substantial muscle weakness in the recovery phase. When neostigmine reversal is used, pancuronium appears to have a similar return of voluntary muscle power to that seen with atracurium. The marked difference in elimination kinetics of these two relaxants seems to be of little importance when neostigmine reversal is used.

The Association Between Handgrip Strength and Diabetes on Activities of Daily Living Disability in Older Mexican Americans

2017 ◽  
Vol 30 (8) ◽  
pp. 1305-1318 ◽  
Author(s):  
Ryan P. McGrath ◽  
Brenda M. Vincent ◽  
Soham Al Snih ◽  
Kyriakos S. Markides ◽  
Brad P. Dieter ◽  
...  
Keyword(s):  
Body Weight ◽  
Confidence Interval ◽  
Activities Of Daily Living ◽  
Grip Strength ◽  
Muscle Weakness ◽  
Mexican Americans ◽  
Daily Living ◽  
Handgrip Strength ◽  
Joint Effects ◽  
Adl Disability

Objective: The aim of this study is to determine the independent and joint effects of muscle weakness and diabetes on incident activities of daily living (ADL) disability in older Mexican Americans. Method: A subsample of 2,270 Mexican Americans aged at least 65 years at baseline were followed for 19 years. Handgrip strength was normalized to body weight (normalized grip strength [NGS]). Weakness was defined as NGS ≤0.46 in males and ≤0.30 in females. Diabetes and ADL disability were self-reported. Results: Compared with participants that were not weak and did not have diabetes, those that had diabetes only, were weak only, and were both weak and had diabetes experienced a 1.94 (95% confidence interval [CI] = [1.89, 1.98]), 1.17 (CI = [1.16, 1.19]), and 2.12 (CI = [2.08, 2.16]) higher rate for ADL disability, respectively. Discussion: Muscle weakness and diabetes were independently and jointly associated with higher rates for ADL disability in older Mexican Americans.

Female Judo Athletes’ Physical Test Performances Are Unrelated to Technical–Tactical Competition Skills

2018 ◽  
Vol 125 (4) ◽  
pp. 802-816 ◽  
Author(s):  
Rafael L. Kons ◽  
Juliano Dal Pupo ◽  
Jonathan Ache-Dias ◽  
Daniele Detanico
Keyword(s):  
Grip Strength ◽  
Power Output ◽  
Muscle Power ◽  
Handgrip Strength ◽  
Linear Regression Analysis ◽  
Peak Power Output ◽  
Countermovement Jump ◽  
Physical Test ◽  
Physical Tests ◽  
Judo Athletes

This study analyzed the relationship between generic and judo-specific physical test performances and technical–tactical competition performances among 19 female judo athletes. Participant data were gathered in two stages: (a) physical tests—countermovement jump (CMJ), handgrip strength, Special Judo Fitness Test and Judogi Grip Strength Test; and (b) match performances recorded for technical–tactical analysis. Pearson’s linear correlation and multiple linear regression analysis showed no significant correlations between any technical–tactical parameter and judo-specific physical tests. However, the number of attacks during matches was significantly positively correlated with countermovement jump height (CMJJH; r = 0.69, p = .002), peak power output (CMJPPO; r = 0.53, p = .002), and peak velocity (CMJPV; r = 0.62, p = .001). Effective time during matches was significantly correlated with all CMJ parameters (except maximum force; r = 0.65−0.76, p ≤ .01) and with right hand grip strength ( r = 0.48, p = .037). Match effectiveness was correlated with CMJPPO ( r = −0.67, p = .001), mean power output (CMJMPO; r = −0.54, p = .017), and CMJPV ( r = −0.54, p = .004). The explained power of variance was low for all variables at 45-54%. We conclude that judo-specific performance tests do not seem to be related to female judo athletes’ technical–tactical skills in official competition, though athletes with higher lower limb muscle power and higher handgrip strength showed higher time effectiveness during matches.

scholarly journals Relation between leg extension power and 30-s sit-to-stand muscle power in older adults: validation and translation to functional performance

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Julian Alcazar ◽  
Rikke S. Kamper ◽  
Per Aagaard ◽  
Bryan Haddock ◽  
Eva Prescott ◽  
...  
Keyword(s):  
Physical Performance ◽  
Lower Limb ◽  
Gait Speed ◽  
Muscle Power ◽  
Handgrip Strength ◽  
Community Dwelling ◽  
Leg Extension ◽  
Sit To Stand ◽  
Significant Difference ◽  
Leg Extension Power

Abstract This study aimed to assess the validity and functional relevance of a standardized procedure to assess lower limb muscle power by means of the 30-s sit-to-stand (STS) test when compared to leg extension power (LEP), traditional STS performance and handgrip strength. A total of 628 community-dwelling older subjects (60–93 years) from the Copenhagen Sarcopenia Study were included. Physical performance was assessed by the 30-s STS and 10-m maximal gait speed tests. Handgrip strength and LEP were recorded by a hand-held dynamometer and the Nottingham power rig, respectively. STS muscle power was calculated using the subjects’ body mass and height, chair height and the number of repetitions completed in the 30-s STS test. We found a small albeit significant difference between LEP and unilateral STS power in older men (245.5 ± 88.8 vs. 223.4 ± 81.4 W; ES = 0.26; p < 0.05), but not in older women (135.9 ± 51.9 vs. 138.5 ± 49.6 W; ES = 0.05; p > 0.05). Notably, a large positive correlation was observed between both measures (r = 0.75; p < 0.001). Relative STS power was more strongly related with maximal gait speed than handgrip strength, repetition-based STS performance and relative LEP after adjusting for age (r = 0.53 vs 0.35–0.45; p < 0.05). In conclusion, STS power obtained from the 30-s STS test appeared to provide a valid measure of bilateral lower limb power and was more strongly related with physical performance than maximal handgrip strength, repetition-based STS performance and LEP.

Influence of Cold Bath on Maximum Handgrip Strength

1977 ◽  
Vol 44 (1) ◽  
pp. 323-326 ◽  
Author(s):  
Dewayne J. Johnson ◽  
Fred E. Leider
Keyword(s):  
Grip Strength ◽  
Repeated Measures ◽  
Handgrip Strength ◽  
Experimental Treatment ◽  
Post Treatment ◽  
Control Treatment ◽  
Time Interval ◽  
Cold Bath ◽  
Treatment Measures ◽  
Pre Treatment

12 female college students participated in a repeated-measures experiment, receiving an experimental treatment and a control treatment. The former was a 30-min. cold bath to the forearm while the control was a similar 30-min. period without the cold bath. Subjects' maximum handgrip strength was measured 11 times, immediately prior to treatment, immediately following treatment, and then every 20 min. for 3 hr. The subjects were tested at the same time of the day, on the same day of the week, for two consecutive weeks. Grip strength was significantly decreased immediately following the experimental treatment below pre-treatment measures and post-treatment measures for the control session. Grip strength during the experimental session significantly increased at 80 min. post-treatment when compared to the strength measures for the control at the same time interval or when compared to pre-treatment measures for either treatment. The strength measures for the two treatments remained significantly different over the rest of the testing occasions.

scholarly journals Força muscular periférica e respiratória na doença pulmonar obstrutiva crônica

2018 ◽  
Vol 20 (2) ◽  
pp. 125-133
Author(s):  
Rudolfo Hummel Gurgel Vieira ◽  
Ivan Daniel Bezerra Nogueira ◽  
Natércia Ferreira Queiroz ◽  
Tamara Martins Cunha ◽  
Zênia Trindade de Souto Araújo ◽  
...  
Keyword(s):  
Muscle Power ◽  
Functional Performance ◽  
Handgrip Strength ◽  
Respiratory Muscles ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Significance Level ◽  
Neuromuscular Performance ◽  
Peripheral Muscle ◽  
Significant Difference

Chronic obstructive pulmonary disease (COPD) is a pulmonary pathology associated with numerous systemic manifestations, among them musculoskeletal dysfunction. The aim of the study was to evaluate and compare respiratory and peripheral muscle strength in patients with COPD and healthy individuals. This is a cross-sectional, analytical and observational study, in which 18 individuals were evaluated, nine of them with COPD and nine healthy. Femoral quadriceps neuromuscular performance (assessed by means of isokinetic dynamometry), handgrip strength (manual dynamometer) and maximum respiratory pressure (manovacuometry) were evaluated. Data were expressed by mean and standard deviation, analyzed in the SPSS 20.0 statistical package. Significance level of 5% and confidence interval of 95% for all measures were considered. Individuals with COPD had lower quadriceps femoral neuromuscular performance and lower respiratory pressures than healthy subjects; however, there was a statistically significant difference only for muscle power and MIP (p <0.05). Handgrip strength was higher in individuals with COPD (p <0.05). individuals with COPD have neuromuscular changes in peripheral and respiratory muscles that may possibly cause reduced functional performance.

scholarly journals Grip Strength-Endurance in Ambitious and Recreational Climbers: Does the Strength Decrement Index Serve as a Feasible Measure?

2020 ◽  
Vol 17 (24) ◽  
pp. 9530
Author(s):  
Berit Kristin Labott ◽  
Steffen Held ◽  
Lars Donath
Keyword(s):  
Grip Strength ◽  
Time Course ◽  
Perceived Exertion ◽  
Handgrip Strength ◽  
Body Height ◽  
Isometric Handgrip ◽  
Right Hand ◽  
Significant Difference ◽  
Left And Right ◽  
Metric Scale

The present study investigated the time course of repetitive maximal isometric grip strength, depending on the arm position, laterality (dominant vs. non-dominant side), and climbing level. The intervention aimed to provide a feasible indicator of maximal strength-endurance in climbing. Seventeen recreational (climbing level (CL): 6.8 (SD 0.5) on the Union Internationale des Associations d’Alpinisme (UIAA) metric scale) and eleven ambitious (CL: 8.7 (SD 0.6) UIAA metric scale) climbers (age: 27 (8) years; BMI: 21.6 (1.9) kg/m2; ape index (arm span divided by body height): 1.05 (0.18); training volume: 2.2 (1.0) h/week). Participants completed maximal isometric handgrip strength (Fmax) tests in four positions (left and right hand beside the trunk as well as left and right hand above the shoulder) plus twelve repetitive work-relief cycles, lasting 4 and 1 s where isometric strength, heart rate, and perceived exertion were recorded. Fmax differed between groups in nearly all positions. A large side × position × time × group interaction was observed for repetitive isometric grip strength (p = 0.009, ηp2 = 0.71). However, subsequent post-hoc tests did not reveal a significant difference between groups during each testing position. Additional correlation analysis between asymmetry and CL showed an inverse relationship for ambitious climbers (r = −0.71). In conclusion, the degree of grip strength decline did not relevantly differentiate between ambitious and recreational climbers. Thus, the time course of handgrip strength seems to mainly rely on maximal grip strength during the first contraction.

scholarly journals Somatostatin infusion withdrawal: studies in the acute and recovery phase of anorexia nervosa, and in obesity

2003 ◽  
pp. 237-243 ◽  
Author(s):  
AI Pincelli ◽  
AE Rigamonti ◽  
M Scacchi ◽  
SG Cella ◽  
M Cappa ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Statistical Significance ◽  
Indirect Evidence ◽  
Recovery Phase ◽  
Normal Weight ◽  
Time Interval ◽  
Free Triiodothyronine ◽  
Significant Difference ◽  
Igf I ◽  
Plasma Gh

OBJECTIVE: Changes in GH/IGF-I axis activity occur in both anorexia nervosa (AN) and obesity (OB). A GH hypersecretory state with very low plasma IGF-I levels is present in AN, whereas in morbid OB, GH secretion is dull and plasma IGF-I levels are generally preserved. Endogenous GHRH activity in AN and OB has never been directly studied, although indirect evidence would indicate that GHRH function is altered in either condition, possibly enhanced and reduced respectively. Somatostatin (SS) infusion withdrawal (SSIW) is followed by a rebound rise of plasma GH in animals and humans, an event which, allegedly, is mediated by endogenous GHRH release. METHODS: In the present study, 28 young women, eight with active AN (A-AN), six with AN in the recovery phase (R-AN), eight with morbid OB, and six healthy age-matched normal weight subjects (NW), were studied. All subjects underwent, on different occasions, the following two tests: (i) acute GHRH injection (1 microg/kg, i.v.); (ii) infusion of SS (9 microg/kg per h i.v. over 60 min), with blood samples drawn prior to and at different intervals after drug injections. Plasma GH levels were measured at each time interval in all sessions, and, in addition, baseline plasma estradiol, free triiodothyronine, TSH, IGF-I and insulin were measured at -30 min. RESULTS: Baseline plasma GH concentrations were significantly higher in A-AN than in NW (4.7+/-0.7 vs 2.1+/-0.6 microg/l, P<0.01). Baseline GH levels in R-AN were also higher than in NW, but the difference did not reach statistical significance (5.6+/-1.7 microg/l, not significant (NS)). Baseline plasma GH concentrations were significantly lower in OB than in NW (0.3+/-0.1 microg/l, P<0.01). GHRH-stimulated GH release was significantly higher in A-AN than in NW (mean change in area under the curve (DeltaAUC) 1904.9+/-626.1 vs 613.9+/-75.9 microg/l per min, P<0.01), whereas no statistically significant difference was present between R-AN and NW (mean DeltaAUC 638.2+/-293.0 microg/l per min, NS); in OB, GHRH failed to evoke a plasma GH rise (mean DeltaAUC 239.8+/-89.9 microg/l per min vs A-AN, R-AN, and NW, P<0.01). SS infusion markedly reduced plasma GH concentrations in both A-AN and R-AN and, to a lesser extent, in NW, but failed to do so in OB. In A-AN, SSIW was followed by a plasma GH rise markedly higher than that present in NW (mean DeltaAUC 193.0+/-42.3 vs 60.1+/-11.4 microg/l per min, P<0.01), whereas in R-AN the GH response after SSIW was nearly superimposable on that registered in NW (mean DeltaAUC 72.9+/-22.8 microg/l per min, NS). There were no changes in plasma GH levels after SSIW in OB (mean DeltaAUC 22.8+/-9.7 microg/l per min). In all groups, DeltaAUCs of the GH response to GHRH and after SSIW were highly positively correlated (r=0.7, P<0.01). CONCLUSIONS: These data support the view that a high endogenous GHRH tone, which subsides in the recovery phase of the disease, is present in AN, whereas GHRH hypofunction, possibly associated with pituitary impairment, might indicate OB.

scholarly journals EFFECTS OF MULLIGAN AND CYRIAX APPROACH IN PATIENTS WITH SUBACUTE LATERAL EPICONDYLITIS

2019 ◽  
Vol 3 (2) ◽  
pp. 107-115
Author(s):  
Sammar Abbas ◽  
◽  
Rabbiya Riaz ◽  
Aqeel Khan ◽  
Anam Javed ◽  
...  
Keyword(s):  
Grip Strength ◽  
Functional Ability ◽  
Tennis Elbow ◽  
Handgrip Strength ◽  
Group Analysis ◽  
Competent Authority ◽  
Lateral Epicondylitis ◽  
Hand Grip Strength ◽  
Hand Grip ◽  
Significant Difference

Objective: To determine and compare the effects of Deep Transverse Friction (DTF) Massage and Mill’s manipulation (Cyriax) with Mobilization with movement (MWM) and Taping (Mulligan) in lateral epicondylitis patients. Material & Methods: A Randomized Control Trial (NCT03848117) was conducted in Physiotherapy Department of DHQ Hospital Bahawalnagar after the approval from the competent authority. Non-probability convenient sampling technique was used to collect sample. The n=30 sample size was randomly allocated in two groups as Group A i.e. the Cyriax group (DTF Massage & Mill’s Manipulation) and Group B i.e. the Mulligan group (Taping & MWM), with 15 participants in each group having sub acute lateral epicondylitis. Data was collected in terms of age, gender, BMI and occupation. Patient related tennis elbow evaluation (PRTEE) questionnaire was used to determine the level of pain, functional disability and hand grip strength. Mann Whitney U statistics test was used for between the group analysis and Friedman with Wilcoxon signed ranks test was used for within the group analysis. The significance level was set at p<0.05. Results: The mean±SD age of subjects in Cyriax group was 33.60±6.864 years and in Mulligan group was 36.93±7.741 years. MWM with taping and Mill’s manipulation with DTF massage both showed significant improvement (p<0.001) in pain, function ability and handgrip strength throughout the treatment duration. When comparing the both group regarding pain, Cyriax approach showed significant improvement after 2nd week while mulligan’s approach showed more improvement than Cyriax approach (p<0.001) in functional ability from 2ndto 3rd week. Hand grip strength in both groups did not show any significant difference (p≥0.05). Conclusion: Mobilization with movement& taping (Mulligan) and mill’s manipulation with DTF massage (Cyriax), both are effective in improving pain, functional ability and handgrip strength in lateral epicondylitis. Cyriax approach is more effective in relieving pain in lateral epicondylitis as compare to Mulligan’s approach. On the other hand, functional ability, more improve with Mulligan’s approach. But both treatments are equally effective in improving hand grip strength in lateral epicondylitis. Keywords: Tennis elbow, mobilization with movement, hand grip strength, patient rated tennis elbow evaluation (PRTEE), Deep Transverse friction massage.

A Comparison of Colectomy Outcomes Utilizing Open, Laparoscopic, and Robotic Techniques

2020 ◽  
pp. 000313482097338
Author(s):  
Elizabeth McCarthy ◽  
Benjamin L. Gough ◽  
Michael S. Johns ◽  
Alexandra Hanlon ◽  
Sachin Vaid ◽  
...  
Keyword(s):  
Postoperative Recovery ◽  
Logistic Regression Models ◽  
Community Institution ◽  
Physical Status Classification ◽  
Estimated Blood Loss ◽  
Comparative Review ◽  
Significant Difference ◽  
American Society ◽  
The Individual ◽  
American Society Of Anesthesiologists

Introduction Robotic colectomy could reduce morbidity and postoperative recovery over laparoscopic and open procedures. This comparative review evaluates colectomy outcomes based on surgical approach at a single community institution. Methods A retrospective review of all patients who underwent colectomy by a fellowship-trained colon and rectal surgeon at a single institution from 2015 through 2019 was performed, and a cohort developed for each approach (open, laparoscopic, and robotic). 30-day outcomes were evaluated. For dichotomous outcomes, univariate logistic regression models were used to quantify the individual effect of each predictor of interest on the odds of each outcome. Continuous outcomes received a similar approach; however, linear and Poisson regression modeling were used, as appropriate. Results 115 patients were evaluated: 14% (n = 16) open, 44% (n = 51) laparoscopic, and 42% (n = 48) robotic. Among the cohorts, there was no statistically significant difference in operative time, rate of reoperation, readmission, or major complications. Robotic colectomies resulted in the shortest length of stay (LOS) (Kruskal-Wallis P < .0001) and decreased estimated blood loss (EBL) (Kruskal-Wallis P = .0012). Median age was 63 years (interquartile range [IQR] 53-72). 54% (n = 62) were female. Median American Society of Anesthesiologists physical status classification was 3 (IQR 2-3). Median body mass index was 28.67 (IQR 25.03-33.47). A malignant diagnosis was noted on final pathology in 44% (n = 51). Conclusion Among the 3 approaches, there was no statistically significant difference in 30-day morbidity or mortality. There was a statistically significant decreased LOS and EBL for robotic colectomies.

scholarly journals Significance of nucleic acid positive anal swab in COVID-19 patients

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 332-337
Author(s):  
Xiaoli Li ◽  
Lei Rong ◽  
Peiyan Zhang ◽  
Jian Xu ◽  
Yan Rong
Keyword(s):  
Platelet Count ◽  
Clinical Symptoms ◽  
Influence Factors ◽  
Recovery Phase ◽  
Negative Group ◽  
Pharyngeal Swab ◽  
Positive Group ◽  
Oral Transmission ◽  
Significant Difference ◽  
Anal Swab

Abstract Aim We compared the clinical characteristics of patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) positive and negative anal swabs during coronavirus disease 2019 (COVID-19) recovery and investigated the clinical significance and influence factors of anal swab detection. Methods This study retrospectively analyzed 23 moderate COVID-19 patients in the recovery phase. They were divided into anal swab positive group (n = 13) (negative for pharyngeal swabs but positive for anal swabs) and anal swab negative group (n = 10) (negative for pharyngeal and anal swabs). The epidemiology, clinical symptoms, time of pharyngeal swabs turning negative, and laboratory results were compared. Results The time of pharyngeal swabs turning negative in the anal swab positive group was 6 (5–8.5) days, significantly longer than that in the anal swab negative group (1 (1–4.25) days), P = 0.0002). The platelet count of the anal swab positive group was significantly lower than that of the anal swab negative group (198 (135–235) × 109/L vs 240.5 (227–264.75) × 109/L, P = 0.0248). No significant difference was observed between the two groups in other variables. Conclusions The time of pharyngeal swab turning negative in anal swab positive patients is longer than that in anal swab negative patients. The platelet count can be used as an indicator for viral infection evaluation. For patients with a longer time of pharyngeal swabs turning negative, the combined testing of the anal swab and platelet counts may help to avoid pharyngeal swab false negatives, premature discharge, and the possibility of fecal-oral transmission.

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