Self-poisonings with Psychopharmacological Agents in Zagreb

1991 ◽  
Vol 10 (5) ◽  
pp. 305-309 ◽  
Author(s):  
G. Miličević ◽  
H. Prpić

1 A 5-year retrospective study of 1743 episodes of self-poisoning in 1608 adult patients, was undertaken to determine the frequency of self-poisoning with psychopharmacological agents, the frequency of each toxic agent usage and the epidemiological characteristics of the poisoned population. 2 The annual incidence of self-poisoning in Zagreb was 38.7 per 100 000 adult inhabitants. The anxiolytic-antipsychotic-antidepressant usage ratio was 8.8:1.5:1.0 in total self-poisoning, whereas it was 4.9:1.5:1.0 in patients with a previous history of self-poisoning. The use of anxiolytics decreased and the use of antidepressants increased during the 5 years. 3 The female—male ratio was 3.8:1 and 77% of self-poisoned persons were aged 15-44 years. The incidence of self-poisoning was 74% higher in the urban than in the rural population. The proportion of self-poisoned persons was 204% higher among the unemployed than in the population as a whole. There were 76% more repetitors among highly educated and 43% fewer repetitors among students than in the general population. The use of antipsychotics was 120% higher in males than in females. The use of antidepressants was 107% higher in the highly educated. 4 The increased use of antidepressants in self-poisoning is an alarming signal and caution in their prescription seems to be indicated.

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 5055-5055
Author(s):  
A. Fortin ◽  
P. Morice ◽  
A. Thoury ◽  
C. Yazbeck ◽  
S. Camatte ◽  
...  

5055 Background: The use of infertility drugs (ID) in infertile patients treated conservatively for ovarian malignancies remains theoretically contraindicated. Few recent case reports seem to suggest that ID could be used in patients treated for a borderline ovarian tumors (BOT). The aim of this multicenter retrospective study was to report the outcomes of the largest series of patients with a previous history of a BOT who underwent the use of ID. Methods: A multicenter retrospective study was conducted among centers which participate in the French National Register on In Vitro Fertilization registry to evaluate the outcomes of patients with a previous history of a BOT treated with ID. Four criteria were defined to select cases: 1. Histologic confirmation of BOT, 2. The use of a conservative surgery, 3. The use of ID and 4. A follow-up ≥ 12 months after the end of infertility treatment. Results: Thirty cases fulfilled inclusion criteria. Infertility therapy began in November 1989. Disease stages were: I (n = 20), II /III with noninvasive implants (n = 8) and unknown in 2 cases. The mean number of cycles of ovarian induction per patient was 2.6 (range,1–10). After a median follow-up of 42 months after infertility treatment, 4 recurrences were observed (all of them were borderline tumors on a remaining ovary treated by surgery alone). All patients are currently disease-free. Thirteen patients have since become pregnant. The median interval between treatment of the BOT and the use of ID is shorter in patients who relapsed compared to patients who did not (5 versus 29 months; p=.07). Conclusions: These results suggest that infertility drugs could be safely used in patients who experience infertility after conservative management of an early-stage BOT. A minimal interval should be respected between treatment of the ovarian tumor and the use of infertility drugs in order to decrease the risk of recurrence. No significant financial relationships to disclose.


2011 ◽  
Vol 26 (S2) ◽  
pp. 2192-2192
Author(s):  
A. Omer

Introduction and objectiveIt's known worldwide that depression is becoming a major health problem and its prevalence is increasing. Unfortunately very few studies were done in our country to verify this. The main objective of this study is to find out the prevalence of depression among patients attending a general psychiatric clinic, and demonstrate their Sociodemographic and clinical features.Type of studyThis is a descriptive retrospective study carried in Khartoum, Sudan.MethodFiles of patients attending a private psychiatric clinical in Khartoum in the period June 2005- June 2010 was reviewed. Only those with diagnosis of depression were chosen, socio demographic date and clinical features were documented, results were shown below.Result and discussionTotal numbers of patients with depression were 137 (11.4%) those with schizophrenia are (13%), meaning that patients with schizophrenia are brought with relatives more than patients with depression. Females are more than males (56.2%), the majority are between ages 41---60 (40.9%), married (65%), (14.9%) has got family history of psychiatric disorders, (52%) has previous history of psychiatric treatment. Regarding clinical features, depressed mood is the commonest symptom (98.5%), loss of interest (91.9%), reduced energy (57%), guilt feelings (17.9%) and (35.8%) of our samples expressed suicidal ideations. The commonest type of somatic symptoms is generalized aches and pain (30.7%). (8%) presented with nihilistic delusions. The most common prescribed antidepressants are SSRI.


2021 ◽  
Vol 6 (4) ◽  
pp. 136-141
Author(s):  
Navneet Kour ◽  
Nadia Irshad Wani ◽  
Parul Sharma

Background: Previous history of periodontitis associated with smoking and poor oral hygiene are considered as one the risk factor for peri-implantitis which in-turn leads to implant failure. Periodontitis is regarded as the most prevalent infectious diseases with around 75% of adults being affected. A similarity between the pathogenesis of periodontitis and peri-implantitis is as a result of intra-oral translocation of periodontal pathogen from teeth showing periodontitis to the peri-implant niche. Aim: The main aim of the study is to evaluate the prevalence of peri-implantitis in patients suffering from periodontitis. Material and Methodology: A retrospective study was conducted in the department of periodontology on 30 patients suffering from periodontitis and with dental implant insertions. In all the patients, periodontal and bone conditions were evaluated. Probing depth, gingival recession, clinical attachment levels, and radiographic bone loss was calculated around the implants, adjacent teeth and contra- lateral teeth to evaluate correlation between periodontitis and implant failures. Results: On evaluation of results with 30 patients, periodontal depth, clinical attachment levels, and gingival recession showed statistically significant around implants when compared with the periodontal parameters around the adjacent teeth and contra-lateral teeth. Non significant results were obtained when radiographic bone loss was evaluated. Conclusion: Within the limitations of the study, it was concluded that dental implant therapy is strongly affected by the periodontal health and health of adjacent teeth plays an important role in determining the failure or success of the implant while contra-lateral teeth have no or minimal relationship between periodontitis and implant failure. Keywords: Implant, Oral Health, Peri-Implantitis, Periodontitis, Translocation.


Author(s):  
Archana Shukla ◽  
Sameer Ahmed

Background: Incisional hernia presents as herniation or protrusion occurring along a prior abdominal scar. It is a known complication of abdominal surgery. They are the second most common type of hernia after inguinal hernias. This study was undertaken to study the incidence and various risk factors leading to incisional hernia.Methods: It is a retrospective study done in Gandhi Medical College, Bhopal; Department of Surgery during January 2017 to January 2018. All the cases were analyzed in various aspects like age, sex, relative incidence, clinical presentation, nature of previous operation, site of previous scar, precipitating factors like obesity, wound infection, abdominal distension.Results: The incidence is around 18.5%. Patients in the age group of 30-50 years found to have highest incidence of incisional hernia. Females outnumbered the males with the ratio of 6:1. Incisional hernia was more common in patients with previous history of gynecological operation. Most of the patients presented with incisional hernia in the infra umbilical region.Conclusions: Incisional hernias can be prevented by avoidance of midline incisions, especially in the infra umbilical region. Mesh repair results in less post-operative complications provided drains are used.


Author(s):  
Anitha Aldur Manjappa ◽  
Maya Menon ◽  
Aruna Bholenath Patil

Background: Gestational diabetes mellitus (GDM) is associated with adverse maternal and fetal outcomes. Majority of the maternal complications associated with GDM have been decreasing nowadays, however the relative risk of development of perinatal complications remain higher in women with hyper glycaemia.Methods: This retrospective study was conducted among 286 delivered pregnant women. The pregnant women were diagnosed as GDM by DIPSI diagnostic criterion. The study was performed to find the association of various risk factors with GDM occurrence and to assess the obstetrical outcome in the GDM and normoglycaemic women.Results: Out of the 286 women, the proportion of women affected with GDM was 20.6%. The onset of GDM was more common among women between 25-30year (62.7%). GDM onset is increased when they had previous history of GDM and family history of diabetes.  The obstetric complications were less common among GDM women (23.72%). GDM women had increased rate of caesarean delivery (69.5%) and induction of labour (42.4%). The neonatal complications were more common among GDM neonates (57.62%). The proportion of occurrence of congenital anomalies and macrosomia (>3.5kg) was similar among both groups.Conclusions: Risk factors associated with GDM onset such as previous history of GDM and family history of diabetes are significant risk factors. Advanced age, increasing parity and occurrence of abortions were not associated with GDM onset.  With good glycaemic control the obstetrical complications and macrosomia are preventable. Rate of Induction of labour, caesarean delivery and neonatal morbidity remains higher among GDM women.


Neurosurgery ◽  
1985 ◽  
Vol 16 (3) ◽  
pp. 290-292 ◽  
Author(s):  
David J. Boarini ◽  
David W. Beck ◽  
John C. VanGilder

Abstract A retrospective study was performed to evaluate the efficacy of prophylactic anticonvulsants in preventing seizures in 68 patients with supratentorial astrocytomas who had been treated with operation and irradiation and who had no previous history of convulsions. Thirty-three patients received prophylactic anticonvulsants and 38 patients did not. The incidence of all types of seizures (generalized convulsions or partial) was lower in patients receiving anticonvulsants. No seizures with an impairment of consciousness occurred in the patients with documented therapeutic anticonvulsant blood levels. The overall incidence of seizures was 39% in untreated patients and 21% in treated patients. The incidence of major seizures including tonic/clonic or partial complex seizures with impairment of consciousness was zero in patients with therapeutic anticonvulsant levels and 18% in untreated patients. Regarding the overall incidence of seizures in both groups, there tend to be fewer seizures in older patients, females, patients with a higher grade of malignancy, and patients who had a more radical resection of the tumor. This study suggests that seizures are a frequent occurrence after operation and irradiation for supratentorial glioma and that anticonvulsants may be effective in reducing the incidence of those seizures.


2011 ◽  
Vol 44 (3) ◽  
pp. 269-273 ◽  
Author(s):  
Luciana da Silveira ◽  
Leonardo de Lucca Schiavon ◽  
Kerley Pereira da Silva ◽  
Thiago Barbieri Lopes ◽  
Marcos da Rocha Zaccaron ◽  
...  

INTRODUCTION: Positive serological tests for hepatitis viruses B and C at blood banks are an important reason for blood deferral. Additionally, high residual risk for transfusing hepatitis-contaminated blood has been estimated in southern Brazil. This study aimed to identify risk factors for positive serological tests for viral hepatitis (VH) in blood donors (BD). METHODS: A case-control study included consecutive BD with positive serology for VH, between 2008 and 2009. Cases and controls (BD with negative serology for VH) were paired 1:1 by sex and donation date. Assessment of clinical and epidemiological characteristics related to viral hepatitis was conducted. RESULTS: Among 1,282 blood donors (641 cases and 641 controls), those with positive serology for viral hepatitis had higher mean age (p<0.001); higher proportion of replacement donation (p<0.001); first donation (p<0.001); and interviewer deferment (p=0.037), compared to controls. Furthermore, donors with positive tests were less regular donors (p<0.001), had less previous history of rejection (p=0.003) and showed lower hematocrit median before donation (p=0.019). Multivariate analysis demonstrated that age (OR=1.056, 95%CI 1.042-1.069, p<0.001), replacement donation (OR=1.545, 95%CI 1.171-2.038, p=0.002) and first donation (OR=9.931, 95%CI 7.486-13.173, p<0.001) were independently associated with positivity of serological tests for viral hepatitis. CONCLUSIONS: Specific characteristics of blood donors were associated with positive serology for viral hepatitis. These peculiarities should be taken into account when assessing candidates for blood donation.


Author(s):  
Sharmila Kumar Gopalan ◽  
Kohila Kalimuthu

Background: Gestational diabetes mellitus (GDM) defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy contributes to about 90% of diabetes complicating pregnancy. GDM imposes risks for both mother and fetus, some of which continues throughout the life of mother and child. The objective of the present study was to determine the prevalence of gestational diabetes mellitus and the associated risk factors among those who delivered in Saveetha medical college and hospital.Methods: A retrospective study was conducted by analysing the medical records of the patients who were admitted in the Department of Obstetrics and Gynaecology over a period of 1 year at Saveetha medical college and hospital, Chennai, Tamil Nadu, India. The diagnosis of GDM was made mainly by 75gm one step oral glucose tolerance test (OGTT). The guideline endorses 2-hours 75-gm OGTT, irrespective of last meal timings with a cut off value of ≥140 mg/dl. All data was analysed by simple descriptive statistics and percentage method.Results: In the present study, the total number of deliveries for 1 year from April 2018 - March 2019 were 511 and among those the total number of antenatal mothers with GDM who delivered were 46. Therefore the prevalence of GDM was calculated to be 9% or 90 per thousand deliveries. In the present study, 37 (65.1%) pregnant women of GDM group were seen in the age group of above 25 years, 27 (58.59%) were multiparous, 25(54.25%) pregnant females with GDM were found to have overweight and obese out of 46 cases.Conclusions: Our current study concludes the Prevalence of GDM in Saveetha Medical College Hospital is 9% between April 2018-March 2019. We have identified the following risk factors for developing GDM: multiparity≥2; previous history of diabetes mellitus; age ≥ 25; BMI ≥25; and family history of diabetes.


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